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Establishment of Community-Based Reference Intervals for Fructosamine, Glycated Albumin, and 1,5-Anhydroglucitol.

Selvin E, Warren B, He X, Sacks DB, Saenger AK.

Clin Chem. 2018 Feb 7. pii: clinchem.2017.285742. doi: 10.1373/clinchem.2017.285742. [Epub ahead of print]


Unraveling the molecular mechanism of interactions of the Rho GTPases Cdc42 and Rac1 with the scaffolding protein IQGAP2.

Ozdemir ES, Jang H, Gursoy A, Keskin O, Li Z, Sacks DB, Nussinov R.

J Biol Chem. 2018 Mar 9;293(10):3685-3699. doi: 10.1074/jbc.RA117.001596. Epub 2018 Jan 22.


Gestational Diabetes Mellitus: Why the Controversy?

Sacks DB, Coustan DR, Cundy T, Donovan L, Hod M.

Clin Chem. 2018 Mar;64(3):431-438. doi: 10.1373/clinchem.2016.266577. Epub 2017 Oct 11. No abstract available.


Refining Measurement of Hemoglobin A1c.

Sacks DB, Bebu I, Lachin JM.

Clin Chem. 2017 Sep;63(9):1433-1435. doi: 10.1373/clinchem.2016.268573. Epub 2017 Jun 20. No abstract available.


Variability in the Relationship of Hemoglobin A1c and Average Glucose Concentrations: How Much Does Race Matter?

Selvin E, Sacks DB.

Ann Intern Med. 2017 Jul 18;167(2):131-132. doi: 10.7326/M17-1231. Epub 2017 Jun 13. No abstract available.


Cross-sectional Analysis of AGE-CML, sRAGE, and esRAGE with Diabetes and Cardiometabolic Risk Factors in a Community-Based Cohort.

Loomis SJ, Chen Y, Sacks DB, Christenson ES, Christenson RH, Rebholz CM, Selvin E.

Clin Chem. 2017 May;63(5):980-989. doi: 10.1373/clinchem.2016.264135. Epub 2017 Mar 9.


Calmodulin Lobes Facilitate Dimerization and Activation of Estrogen Receptor-α.

Li Z, Zhang Y, Hedman AC, Ames JB, Sacks DB.

J Biol Chem. 2017 Mar 17;292(11):4614-4622. doi: 10.1074/jbc.M116.754804. Epub 2017 Feb 7.


Association of Sickle Cell Trait With Hemoglobin A1c in African Americans.

Lacy ME, Wellenius GA, Sumner AE, Correa A, Carnethon MR, Liem RI, Wilson JG, Sacks DB, Jacobs DR Jr, Carson AP, Luo X, Gjelsvik A, Reiner AP, Naik RP, Liu S, Musani SK, Eaton CB, Wu WC.

JAMA. 2017 Feb 7;317(5):507-515. doi: 10.1001/jama.2016.21035.


Absence of IQGAP1 Protein Leads to Insulin Resistance.

Chawla B, Hedman AC, Sayedyahossein S, Erdemir HH, Li Z, Sacks DB.

J Biol Chem. 2017 Feb 24;292(8):3273-3289. doi: 10.1074/jbc.M116.752642. Epub 2017 Jan 12.


Monitoring Glycemic Control in End-Stage Renal Disease: What Should Be Measured?

Selvin E, Sacks DB.

Clin Chem. 2017 Feb;63(2):447-449. doi: 10.1373/clinchem.2016.265744. Epub 2016 Dec 14. No abstract available.


Agonist-stimulated phosphatidylinositol-3,4,5-trisphosphate generation by scaffolded phosphoinositide kinases.

Choi S, Hedman AC, Sayedyahossein S, Thapa N, Sacks DB, Anderson RA.

Nat Cell Biol. 2016 Dec;18(12):1324-1335. doi: 10.1038/ncb3441. Epub 2016 Nov 21.


Glycated Albumin Identifies Prediabetes Not Detected by Hemoglobin A1c: The Africans in America Study.

Sumner AE, Duong MT, Bingham BA, Aldana PC, Ricks M, Mabundo LS, Tulloch-Reid MK, Chung ST, Sacks DB.

Clin Chem. 2016 Nov;62(11):1524-1532. Epub 2016 Sep 13.


Deletion of IQGAP1 promotes Helicobacter pylori-induced gastric dysplasia in mice and acquisition of cancer stem cell properties in vitro.

Bessède E, Molina S, Acuña-Amador L, Dubus P, Staedel C, Chambonnier L, Buissonnière A, Sifré E, Giese A, Bénéjat L, Rousseau B, Costet P, Sacks DB, Mégraud F, Varon C.

Oncotarget. 2016 Dec 6;7(49):80688-80699. doi: 10.18632/oncotarget.12486.


Role of IQGAP1 in endothelial barrier enhancement caused by OxPAPC.

Tian Y, Tian X, Gawlak G, Sarich N, Sacks DB, Birukova AA, Birukov KG.

Am J Physiol Lung Cell Mol Physiol. 2016 Aug 26:ajplung.00095.2016. doi: 10.1152/ajplung.00095.2016. [Epub ahead of print]


The Structural Basis for Cdc42-Induced Dimerization of IQGAPs.

LeCour L Jr, Boyapati VK, Liu J, Li Z, Sacks DB, Worthylake DK.

Structure. 2016 Sep 6;24(9):1499-508. doi: 10.1016/j.str.2016.06.016. Epub 2016 Aug 11.


Role of Glycated Proteins in the Diagnosis and Management of Diabetes: Research Gaps and Future Directions.

Welsh KJ, Kirkman MS, Sacks DB.

Diabetes Care. 2016 Aug;39(8):1299-306. doi: 10.2337/dc15-2727. No abstract available.


IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity.

Sayedyahossein S, Li Z, Hedman AC, Morgan CJ, Sacks DB.

J Biol Chem. 2016 Sep 9;291(37):19261-73. doi: 10.1074/jbc.M116.732529. Epub 2016 Jul 20.


Hemoglobin A1c and Race: Should Therapeutic Targets and Diagnostic Cutoffs Differ among Racial Groups?

Sacks DB.

Clin Chem. 2016 Sep;62(9):1199-201. doi: 10.1373/clinchem.2016.255166. Epub 2016 Jul 7. No abstract available.


Higher degree of glycation of hemoglobin S compared to hemoglobin A measured by mass spectrometry: Potential impact on HbA1c testing.

Kabytaev K, Connolly S, Rohlfing CL, Sacks DB, Stoyanov AV, Little RR.

Clin Chim Acta. 2016 Jul 1;458:40-3. doi: 10.1016/j.cca.2016.04.027. Epub 2016 Apr 22.


Increased Pleiotrophin Concentrations in Papillary Thyroid Cancer.

Jee YH, Sadowski SM, Celi FS, Xi L, Raffeld M, Sacks DB, Remaley AT, Wellstein A, Kebebew E, Baron J.

PLoS One. 2016 Feb 25;11(2):e0149383. doi: 10.1371/journal.pone.0149383. eCollection 2016.


A1C Combined With Glycated Albumin Improves Detection of Prediabetes in Africans: The Africans in America Study.

Sumner AE, Duong MT, Aldana PC, Ricks M, Tulloch-Reid MK, Lozier JN, Chung ST, Sacks DB.

Diabetes Care. 2016 Feb;39(2):271-7. doi: 10.2337/dc15-1699. Epub 2015 Dec 17.


Detrimental Effects of Not Using International Reference Materials to Calibrate Cystatin C Assays.

Zhao Z, Sacks DB.

Clin Chem. 2016 Feb;62(2):410-1. doi: 10.1373/clinchem.2015.244988. Epub 2015 Nov 9. No abstract available.


Identification of Microorganisms by High Resolution Tandem Mass Spectrometry with Accurate Statistical Significance.

Alves G, Wang G, Ogurtsov AY, Drake SK, Gucek M, Suffredini AF, Sacks DB, Yu YK.

J Am Soc Mass Spectrom. 2016 Feb;27(2):194-210. doi: 10.1007/s13361-015-1271-2. Epub 2015 Oct 28.


Development of the Diabetes Technology Society Blood Glucose Monitor System Surveillance Protocol.

Klonoff DC, Lias C, Beck S, Parkes JL, Kovatchev B, Vigersky RA, Arreaza-Rubin G, Burk RD, Kowalski A, Little R, Nichols J, Petersen M, Rawlings K, Sacks DB, Sampson E, Scott S, Seley JJ, Slingerland R, Vesper HW.

J Diabetes Sci Technol. 2016 May 3;10(3):697-707. doi: 10.1177/1932296815614587. Print 2016 May.


Shigella Effector OspB Activates mTORC1 in a Manner That Depends on IQGAP1 and Promotes Cell Proliferation.

Lu R, Herrera BB, Eshleman HD, Fu Y, Bloom A, Li Z, Sacks DB, Goldberg MB.

PLoS Pathog. 2015 Oct 16;11(10):e1005200. doi: 10.1371/journal.ppat.1005200. eCollection 2015 Oct.


Evaluation of hemoglobin A1c measurement by Capillarys 2 electrophoresis for detection of abnormal glucose tolerance in African immigrants to the United States.

Zhao Z, Basilio J, Hanson S, Little RR, Sumner AE, Sacks DB.

Clin Chim Acta. 2015 Jun 15;446:54-60. doi: 10.1016/j.cca.2015.03.025. Epub 2015 Apr 8.


Investigation of 2 models to set and evaluate quality targets for hb a1c: biological variation and sigma-metrics.

Weykamp C, John G, Gillery P, English E, Ji L, Lenters-Westra E, Little RR, Roglic G, Sacks DB, Takei I; IFCC Task Force on Implementation of HbA1c Standardization.

Clin Chem. 2015 May;61(5):752-9. doi: 10.1373/clinchem.2014.235333. Epub 2015 Mar 3.


The biology of IQGAP proteins: beyond the cytoskeleton.

Hedman AC, Smith JM, Sacks DB.

EMBO Rep. 2015 Apr;16(4):427-46. doi: 10.15252/embr.201439834. Epub 2015 Feb 26. Review.


Plasmonic chip tackles type 1 diabetes diagnosis.

Sacks DB, Kricka LJ.

Clin Chem. 2015 Jun;61(6):794-6. doi: 10.1373/clinchem.2014.233346. Epub 2015 Feb 5. No abstract available.


IQGAPs choreograph cellular signaling from the membrane to the nucleus.

Smith JM, Hedman AC, Sacks DB.

Trends Cell Biol. 2015 Mar;25(3):171-84. doi: 10.1016/j.tcb.2014.12.005. Epub 2015 Jan 21. Review.


IQGAP1 controls tight junction formation through differential regulation of claudin recruitment.

Tanos BE, Perez Bay AE, Salvarezza S, Vivanco I, Mellinghoff I, Osman M, Sacks DB, Rodriguez-Boulan E.

J Cell Sci. 2015 Mar 1;128(5):853-62. doi: 10.1242/jcs.118703. Epub 2015 Jan 14.


The surveillance error grid.

Klonoff DC, Lias C, Vigersky R, Clarke W, Parkes JL, Sacks DB, Kirkman MS, Kovatchev B; Error Grid Panel.

J Diabetes Sci Technol. 2014 Jul;8(4):658-72. doi: 10.1177/1932296814539589. Epub 2014 Jun 13.


Hepatocyte growth factor-induced Asef-IQGAP1 complex controls cytoskeletal remodeling and endothelial barrier.

Tian Y, Gawlak G, Shah AS, Higginbotham K, Tian X, Kawasaki Y, Akiyama T, Sacks DB, Birukova AA.

J Biol Chem. 2015 Feb 13;290(7):4097-109. doi: 10.1074/jbc.M114.620377. Epub 2014 Dec 9.


Interference of cerebrospinal fluid total protein measurement by povidone-iodine contamination.

Gounden V, Sacks DB, Zhao Z.

Clin Chim Acta. 2015 Feb 2;440:3-5. doi: 10.1016/j.cca.2014.10.008. Epub 2014 Oct 16.


Midkine concentrations in fine-needle aspiration of benign and malignant thyroid nodules.

Jee YH, Celi FS, Sampson M, Sacks DB, Remaley AT, Kebebew E, Baron J.

Clin Endocrinol (Oxf). 2015 Dec;83(6):977-84. doi: 10.1111/cen.12676. Epub 2015 Jan 15.


Detection of abnormal glucose tolerance in Africans is improved by combining A1C with fasting glucose: the Africans in America Study.

Sumner AE, Thoreson CK, O'Connor MY, Ricks M, Chung ST, Tulloch-Reid MK, Lozier JN, Sacks DB.

Diabetes Care. 2015 Feb;38(2):213-9. doi: 10.2337/dc14-1179. Epub 2014 Oct 22.


Multicentre evaluation of the Premier Hb9210 HbA1c analyser.

John WG, Little R, Sacks DB, Weykamp C, Lenters-Westra E, Hornsby T, Zhao Z, Siebelder C, Tennill A, English E.

Clin Chem Lab Med. 2015 Feb;53(2):319-27. doi: 10.1515/cclm-2014-0589.



Sacks DB.

Clin Chem. 2014 Oct;60(10):1271-2. doi: 10.1373/clinchem.2014.221408. No abstract available.


IQGAP1 regulates endothelial barrier function via EB1-cortactin cross talk.

Tian Y, Tian X, Gawlak G, O'Donnell JJ 3rd, Sacks DB, Birukova AA.

Mol Cell Biol. 2014 Sep 15;34(18):3546-58. doi: 10.1128/MCB.00248-14. Epub 2014 Jul 14.


Interpretation of hemoglobin A1c values.

Sacks DB, John WG.

JAMA. 2014 Jun 11;311(22):2271-2. doi: 10.1001/jama.2014.6342. No abstract available.


Trends in prevalence and control of diabetes in the United States, 1988-1994 and 1999-2010.

Selvin E, Parrinello CM, Sacks DB, Coresh J.

Ann Intern Med. 2014 Apr 15;160(8):517-25. doi: 10.7326/M13-2411.


Comparing analytic performance criteria: evaluation of HbA1c certification criteria as an example.

Rohlfing CL, Parvin CA, Sacks DB, Little RR; NGSP Steering Committee.

Clin Chim Acta. 2014 Jun 10;433:259-63. doi: 10.1016/j.cca.2014.03.034. Epub 2014 Apr 8.


IQGAP1 binds to estrogen receptor-α and modulates its function.

Erdemir HH, Li Z, Sacks DB.

J Biol Chem. 2014 Mar 28;289(13):9100-12. doi: 10.1074/jbc.M114.553511. Epub 2014 Feb 18.


Islet autoantibodies and type 1 diabetes: does the evidence support screening?

Calderon B, Sacks DB.

Clin Chem. 2014 Mar;60(3):438-40. doi: 10.1373/clinchem.2013.212381. Epub 2013 Dec 20. No abstract available.


A PAK6-IQGAP1 complex promotes disassembly of cell-cell adhesions.

Fram S, King H, Sacks DB, Wells CM.

Cell Mol Life Sci. 2014 Jul;71(14):2759-73. doi: 10.1007/s00018-013-1528-5. Epub 2013 Dec 19.


Wnt5a directs polarized calcium gradients by recruiting cortical endoplasmic reticulum to the cell trailing edge.

Witze ES, Connacher MK, Houel S, Schwartz MP, Morphew MK, Reid L, Sacks DB, Anseth KS, Ahn NG.

Dev Cell. 2013 Sep 30;26(6):645-57. doi: 10.1016/j.devcel.2013.08.019.


Diagnosis of gestational diabetes mellitus: it is time for international consensus.

Sacks DB.

Clin Chem. 2014 Jan;60(1):141-3. doi: 10.1373/clinchem.2013.206920. Epub 2013 Sep 23. No abstract available.


IQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration.

Choi S, Thapa N, Hedman AC, Li Z, Sacks DB, Anderson RA.

EMBO J. 2013 Oct 2;32(19):2617-30. doi: 10.1038/emboj.2013.191. Epub 2013 Aug 27.


Reporting hemoglobin A1c: do the units matter?

Sacks DB.

Clin Chem. 2013 Oct;59(10):1427-9. doi: 10.1373/clinchem.2013.211227. Epub 2013 Jul 22. No abstract available.


The Ras GTPase-activating-like protein IQGAP1 mediates Nrf2 protein activation via the mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK)-ERK pathway.

Cheung KL, Lee JH, Shu L, Kim JH, Sacks DB, Kong AN.

J Biol Chem. 2013 Aug 2;288(31):22378-86. doi: 10.1074/jbc.M112.444182. Epub 2013 Jun 20.

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