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The prognostic impact of cancer stem-like cell biomarker aldehyde dehydrogenase-1 (ALDH1) in ovarian cancer: A meta-analysis.

Ruscito I, Darb-Esfahani S, Kulbe H, Bellati F, Zizzari IG, Rahimi Koshkaki H, Napoletano C, Caserta D, Rughetti A, Kessler M, Sehouli J, Nuti M, Braicu EI.

Gynecol Oncol. 2018 May 10. pii: S0090-8258(18)30892-8. doi: 10.1016/j.ygyno.2018.05.006. [Epub ahead of print]


TK Inhibitor Pazopanib Primes DCs by Downregulation of the β-Catenin Pathway.

Zizzari IG, Napoletano C, Botticelli A, Caponnetto S, Calabrò F, Gelibter A, Rughetti A, Ruscito I, Rahimi H, Rossi E, Schinzari G, Marchetti P, Nuti M.

Cancer Immunol Res. 2018 Apr 26. doi: 10.1158/2326-6066.CIR-17-0594. [Epub ahead of print]


Anisakis pegreffii impacts differentiation and function of human dendritic cells.

Napoletano C, Mattiucci S, Colantoni A, Battisti F, Zizzari IG, Rahimi H, Nuti M, Rughetti A.

Parasite Immunol. 2018 May;40(5):e12527. doi: 10.1111/pim.12527.


Leukocyte depletion does not affect the in vitro healing ability of platelet rich plasma.

Giusti I, Di Francesco M, D'Ascenzo S, Palumbo P, Rughetti A, Dell'Orso L, Varasano PA, Pressanti GL, Dolo V.

Exp Ther Med. 2018 Apr;15(4):4029-4038. doi: 10.3892/etm.2018.5887. Epub 2018 Feb 22.


Tumor-Derived Microvesicles Modulate Antigen Cross-Processing via Reactive Oxygen Species-Mediated Alkalinization of Phagosomal Compartment in Dendritic Cells.

Battisti F, Napoletano C, Rahimi Koshkaki H, Belleudi F, Zizzari IG, Ruscito I, Palchetti S, Bellati F, Benedetti Panici P, Torrisi MR, Caracciolo G, Altieri F, Nuti M, Rughetti A.

Front Immunol. 2017 Sep 25;8:1179. doi: 10.3389/fimmu.2017.01179. eCollection 2017.


Microfracture versus microfracture and platelet-rich plasma: arthroscopic treatment of knee chondral lesions. A two-year follow-up study.

Mancò A, Goderecci R, Rughetti A, DE Giorgi S, Necozione S, Bernardi A, Calvisi V.

Joints. 2016 Sep 21;4(3):142-147. eCollection 2016 Jul-Sep.


Immunological and Clinical Impact of Cancer Stem Cells in Vulvar Cancer: Role of CD133/CD24/ABCG2-Expressing Cells.

Napoletano C, Bellati F, Ruscito I, Pernice M, Zizzari IG, Caponnetto S, Tomao F, Frigerio L, Liberati M, Rughetti A, Caserta D, Panici PB, Nuti M.

Anticancer Res. 2016 Oct;36(10):5109-5116.


In normal aging ventricular system never attains pathological values of Evans' index.

Missori P, Rughetti A, Peschillo S, Gualdi G, Di Biasi C, Nofroni I, Marinelli L, Fattapposta F, Currà A.

Oncotarget. 2016 Mar 15;7(11):11860-3. doi: 10.18632/oncotarget.7644.


Triple peptide vaccination as consolidation treatment in women affected by ovarian and breast cancer: Clinical and immunological data of a phase I/II clinical trial.

Antonilli M, Rahimi H, Visconti V, Napoletano C, Ruscito I, Zizzari IG, Caponnetto S, Barchiesi G, Iadarola R, Pierelli L, Rughetti A, Bellati F, Panici PB, Nuti M.

Int J Oncol. 2016 Apr;48(4):1369-78. doi: 10.3892/ijo.2016.3386. Epub 2016 Feb 8.


MGL Receptor and Immunity: When the Ligand Can Make the Difference.

Zizzari IG, Napoletano C, Battisti F, Rahimi H, Caponnetto S, Pierelli L, Nuti M, Rughetti A.

J Immunol Res. 2015;2015:450695. doi: 10.1155/2015/450695. Epub 2015 Dec 29. Review.


The Macrophage Galactose-Type C-Type Lectin (MGL) Modulates Regulatory T Cell Functions.

Zizzari IG, Martufi P, Battisti F, Rahimi H, Caponnetto S, Bellati F, Nuti M, Rughetti A, Napoletano C.

PLoS One. 2015 Jul 6;10(7):e0132617. doi: 10.1371/journal.pone.0132617. eCollection 2015.


Infected Nonhealing Wound in a Kidney Transplant Recipient: Successful Treatment With Topical Homologous Platelet-Rich Gel.

Iesari S, Lai Q, Rughetti A, Dell'Orso L, Clemente K, Famulari A, Pisani F, Favi E.

Exp Clin Transplant. 2017 Apr;15(2):222-225. doi: 10.6002/ect.2014.0236. Epub 2015 Jun 15.


Oral Platelet Gel Supernatant Plus Supportive Medical Treatment Versus Supportive Medical Treatment in the Management of Radiation-induced Oral Mucositis: A Matched Explorative Active Control Trial by Propensity Analysis.

Bonfili P, Gravina GL, Marampon F, Rughetti A, Di Staso M, Dell'Orso L, Vittorini F, Moro R, La Verghetta ME, Parente S, Reale M, Ruggieri V, Franzese P, Tombolini V, Masciocchi C, Di Cesare E.

Am J Clin Oncol. 2017 Aug;40(4):336-341. doi: 10.1097/COC.0000000000000177.


Platelet concentration in platelet-rich plasma affects tenocyte behavior in vitro.

Giusti I, D'Ascenzo S, Mancò A, Di Stefano G, Di Francesco M, Rughetti A, Dal Mas A, Properzi G, Calvisi V, Dolo V.

Biomed Res Int. 2014;2014:630870. doi: 10.1155/2014/630870. Epub 2014 Jul 23.


Rapid resolution of refractory chemotherapy-induced oral mucositis with platelet gel-released supernatant in a pediatric cancer patient: a case report.

Aielli F, Giusti R, Rughetti A, dell'Orso L, Ficorella C, Porzio G.

J Pain Symptom Manage. 2014 Nov;48(5):e2-4. doi: 10.1016/j.jpainsymman.2014.06.015. Epub 2014 Aug 15. No abstract available.


Microvesicle cargo of tumor-associated MUC1 to dendritic cells allows cross-presentation and specific carbohydrate processing.

Rughetti A, Rahimi H, Belleudi F, Napoletano C, Battisti F, Zizzari IG, Antonilli M, Bellati F, Wandall HH, Benedetti Panici P, Burchell JM, Torrisi MR, Nuti M.

Cancer Immunol Res. 2014 Feb;2(2):177-86. doi: 10.1158/2326-6066.CIR-13-0112-T. Epub 2013 Oct 28.


Topical application of platelet supernatant gel in the management of radiotherapy-induced mucositis: a case report.

Di Staso M, Rughetti A, Dell'Orso L, Marampon F, La Verghetta ME, Parente S, Gravina GL, Aielli F, Dolo V, Ruggieri V, Franzese P, Bonfili P, Tombolini V, Di Cesare E.

Blood Transfus. 2014 Jan;12(1):107-10. doi: 10.2450/2013.0104-13. Epub 2013 Oct 22. No abstract available.


The effects of platelet gel-released supernatant on human fibroblasts.

Giusti I, Rughetti A, D'Ascenzo S, Di Stefano G, Nanni MR, Millimaggi D, Dell'orso L, Dolo V.

Wound Repair Regen. 2013 Mar-Apr;21(2):300-8. doi: 10.1111/wrr.12025. Epub 2013 Feb 25.


Past, present and future strategies of immunotherapy in gynecological malignancies.

Bellati F, Napoletano C, Ruscito I, Visconti V, Antonilli M, Gasparri ML, Zizzari IG, Rahimi H, Palaia I, Rughetti A, Benedetti Panici P, Nuti M.

Curr Mol Med. 2013 May;13(4):648-69.


Targeting of macrophage galactose-type C-type lectin (MGL) induces DC signaling and activation.

Napoletano C, Zizzari IG, Rughetti A, Rahimi H, Irimura T, Clausen H, Wandall HH, Belleudi F, Bellati F, Pierelli L, Frati L, Nuti M.

Eur J Immunol. 2012 Apr;42(4):936-45. doi: 10.1002/eji.201142086.


Monoclonal antibodies in gynecological cancer: a critical point of view.

Bellati F, Napoletano C, Gasparri ML, Visconti V, Zizzari IG, Ruscito I, Caccetta J, Rughetti A, Benedetti-Panici P, Nuti M.

Clin Dev Immunol. 2011;2011:890758. doi: 10.1155/2011/890758. Epub 2011 Dec 26. Review.


HER2-based recombinant immunogen to target DCs through FcγRs for cancer immunotherapy.

Zizzari IG, Veglia F, Taurino F, Rahimi H, Quaglino E, Belleudi F, Riccardo F, Antonilli M, Napoletano C, Bellati F, Benedetti-Panici P, Torrisi MR, Frati L, Nuti M, Rughetti A.

J Mol Med (Berl). 2011 Dec;89(12):1231-40. doi: 10.1007/s00109-011-0794-7. Epub 2011 Aug 16.


Immune effects of trastuzumab.

Nuti M, Bellati F, Visconti V, Napoletano C, Domenici L, Caccetta J, Zizzari IG, Ruscito I, Rahimi H, Benedetti-Panici P, Rughetti A.

J Cancer. 2011;2:317-23. Epub 2011 May 25.


Immunogenicity of allo-vesicle carrying ERBB2 tumor antigen for dendritic cell-based anti-tumor immunotherapy.

Napoletano C, Rughetti A, Landi R, Pinto D, Bellati F, Rahimi H, Spinelli GP, Pauselli S, Sale P, Dolo V, De Lorenzo F, Tomao F, Benedetti-Panici P, Frati L, Nuti M.

Int J Immunopathol Pharmacol. 2009 Jul-Sep;22(3):647-58.


Ovarian cancer cytoreduction induces changes in T cell population subsets reducing immunosuppression.

Napoletano C, Bellati F, Landi R, Pauselli S, Marchetti C, Visconti V, Sale P, Liberati M, Rughetti A, Frati L, Panici PB, Nuti M.

J Cell Mol Med. 2010 Dec;14(12):2748-59. doi: 10.1111/j.1582-4934.2009.00911.x.


Identification of an optimal concentration of platelet gel for promoting angiogenesis in human endothelial cells.

Giusti I, Rughetti A, D'Ascenzo S, Millimaggi D, Pavan A, Dell'Orso L, Dolo V.

Transfusion. 2009 Apr;49(4):771-8. doi: 10.1111/j.1537-2995.2008.02033.x. Epub 2008 Dec 23.


Platelet gel-released supernatant modulates the angiogenic capability of human endothelial cells.

Rughetti A, Giusti I, D'Ascenzo S, Leocata P, Carta G, Pavan A, Dell'Orso L, Dolo V.

Blood Transfus. 2008 Jan;6(1):12-7.


RFA strongly modulates the immune system and anti-tumor immune responses in metastatic liver patients.

Napoletano C, Taurino F, Biffoni M, De Majo A, Coscarella G, Bellati F, Rahimi H, Pauselli S, Pellicciotta I, Burchell JM, Gaspari LA, Ercoli L, Rossi P, Rughetti A.

Int J Oncol. 2008 Feb;32(2):481-90.


MAGE-A and NY-ESO-1 expression in cervical cancer: prognostic factors and effects of chemotherapy.

Napoletano C, Bellati F, Tarquini E, Tomao F, Taurino F, Spagnoli G, Rughetti A, Muzii L, Nuti M, Benedetti Panici P.

Am J Obstet Gynecol. 2008 Jan;198(1):99.e1-7. doi: 10.1016/j.ajog.2007.05.019.


Cancer testis antigen expression in primary and recurrent vulvar cancer: association with prognostic factors.

Bellati F, Napoletano C, Tarquini E, Palaia I, Landi R, Manci N, Spagnoli G, Rughetti A, Panici PB, Nuti M.

Eur J Cancer. 2007 Nov;43(17):2621-7. Epub 2007 Oct 22.


Tumor-associated Tn-MUC1 glycoform is internalized through the macrophage galactose-type C-type lectin and delivered to the HLA class I and II compartments in dendritic cells.

Napoletano C, Rughetti A, Agervig Tarp MP, Coleman J, Bennett EP, Picco G, Sale P, Denda-Nagai K, Irimura T, Mandel U, Clausen H, Frati L, Taylor-Papadimitriou J, Burchell J, Nuti M.

Cancer Res. 2007 Sep 1;67(17):8358-67.


A comparative analysis of serum and serum-free media for generation of clinical grade DCs.

Napoletano C, Pinto D, Bellati F, Taurino F, Rahimi H, Tomao F, Panici PB, Rughetti A, Frati L, Nuti M.

J Immunother. 2007 Jul-Aug;30(5):567-76.


Modulation of blood circulating immune cells by radiofrequency tumor ablation.

Rughetti A, Rahimi H, Rossi P, Frati L, Nuti M, Gaspari A, Danza FM, Ercoli L.

J Exp Clin Cancer Res. 2003 Dec;22(4 Suppl):247-50.


Recombinant tumor-associated MUC1 glycoprotein impairs the differentiation and function of dendritic cells.

Rughetti A, Pellicciotta I, Biffoni M, Bäckström M, Link T, Bennet EP, Clausen H, Noll T, Hansson GC, Burchell JM, Frati L, Taylor-Papadimitriou J, Nuti M.

J Immunol. 2005 Jun 15;174(12):7764-72.


Sialylated core 1 based O-linked glycans enhance the growth rate of mammary carcinoma cells in MUC1 transgenic mice.

Mungul A, Cooper L, Brockhausen I, Ryder K, Mandel U, Clausen H, Rughetti A, Miles DW, Taylor-Papadimitriou J, Burchell JM.

Int J Oncol. 2004 Oct;25(4):937-43.


Regulated expression of MUC1 epithelial antigen in erythropoiesis.

Rughetti A, Biffoni M, Pierelli L, Rahimi H, Bonanno G, Barachini S, Pellicciotta I, Napoletano C, Pescarmona E, Del Nero A, Pignoloni P, Frati L, Nuti M.

Br J Haematol. 2003 Jan;120(2):344-52.


The role of growth factor administration and T-cell recovery after peripheral blood progenitor cell transplantation in the treatment of solid tumors: results from a randomized comparison of G-CSF and GM-CSF.

Pierelli L, Perillo A, Ferrandina G, Salerno G, Rutella S, Fattorossi A, Battaglia A, Rughetti A, Nuti M, Cortesi E, Leone G, Mancuso S, Scambia G.

Transfusion. 2001 Dec;41(12):1577-85.


Effects of granulocyte-colony-stimulating factor and granulocyte/macrophage-colony-stimulating factor administration on T cell proliferation and phagocyte cell-surface molecules during hematopoietic reconstitution after autologous peripheral blood progenitor cell transplantation.

Fattorossi A, Battaglia A, Pierelli L, Malinconico P, Andreocci L, Perillo A, Ferrandina G, Martelli O, Rughetti A, Nuti M, Cortesi E, Scambia G.

Cancer Immunol Immunother. 2001 Feb;49(12):641-8.


Transfected human dendritic cells to induce antitumor immunity.

Rughetti A, Biffoni M, Sabbatucci M, Rahimi H, Pellicciotta I, Fattorossi A, Pierelli L, Scambia G, Lavitrano M, Frati L, Nuti M.

Gene Ther. 2000 Sep;7(17):1458-66.


Human decay accelerating factor transgenic pigs for xenotransplantation obtained by sperm-mediated gene transfer.

Lavitrano M, Stoppacciaro A, Bacci ML, Forni M, Fioretti D, Pucci L, Di Stefano C, Lazzereschi D, Rughetti A, Ceretta S, Zannoni A, Rahimi H, Moioli B, Rossi M, Nuti M, Rossi G, Seren E, Alfani D, Cortesini R, Frati L.

Transplant Proc. 1999 Feb-Mar;31(1-2):972-4. No abstract available.


Isolation of MUC1-primed B lymphocytes from tumour-draining lymph nodes by immunomagnetic beads.

Petrarca C, Casalino B, von Mensdorff-Pouilly S, Rughetti A, Rahimi H, Scambia G, Hilgers J, Frati L, Nuti M.

Cancer Immunol Immunother. 1999 Jan;47(5):272-7.


Human antibodies against the polymorphic epithelial mucin in ovarian cancer patients recognise a novel sequence in the tandem repeat region.

Petrarca C, Rughetti A, Rahimi H, D'Agostini F, Turchi V, Apollonj Ghetti C, Scambia G, Frati L, Nuti M.

Eur J Cancer. 1996 Nov;32A(12):2155-63.


The epithelial mucin MUC1 contains at least two discrete signals specifying membrane localization in cells.

Pemberton LF, Rughetti A, Taylor-Papadimitriou J, Gendler SJ.

J Biol Chem. 1996 Jan 26;271(4):2332-40.


bcl-2 overexpression inhibits cell death and promotes the morphogenesis, but not tumorigenesis of human mammary epithelial cells.

Lu PJ, Lu QL, Rughetti A, Taylor-Papadimitriou J.

J Cell Biol. 1995 Jun;129(5):1363-78. Erratum in: J Cell Biol 1995 Nov;131(4):following 1121.


Human B cell immune response to selected epitopes of the polymorphic epithelial mucin (PEM) in cancer patients.

Nuti M, Rughetti A, Turchi V, Apollonj-Ghetti C, Scambia G, Frati L.

In Vivo. 1993 Nov-Dec;7(6B):645-7.


Human B-cell immune response to the polymorphic epithelial mucin.

Rughetti A, Turchi V, Ghetti CA, Scambia G, Panici PB, Roncucci G, Mancuso S, Frati L, Nuti M.

Cancer Res. 1993 Jun 1;53(11):2457-9.


Immunohistochemical analysis of the distribution of a breast tumor associated antigen recognized by a monoclonal antibody.

Castagna M, Viacava P, Turchi V, Rughetti A, Nuti M, Squartini F.

Pathol Res Pract. 1992 Dec;188(8):1002-8.


Characterization of monoclonal antibody 436 recognizing the Arg-Pro-Ala-Pro sequence of the polymorphic epithelial mucin (PEM) protein core in breast carcinoma cells.

Nuti M, Turchi V, Rughetti A, Viacava P, Masci AM, Castagna M, Frati L.

Int J Biol Markers. 1992 Apr-Jun;7(2):71-9.


[Concentration test for determination of low-level HBsAg in donors with anti-HBc].

Maschio C, Varrassi S, Barnabei R, Rughetti A, Fonzi D, Capulli M, Genise S.

Riv Emoter Immunoematol. 1985;32(1):69-73. Italian. No abstract available.


[Laboratory results in the evaluation of anti HTLV-III in subjects at risk].

Maschio C, Colangeli S, Rughetti A, Fonzi D, Barnabei R, Ciccarella A.

Riv Emoter Immunoematol. 1985;32(3):302-6. Italian. No abstract available.


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