Sort by
Items per page

Send to

Choose Destination

Search results

Items: 44


Mitotic spindle association of TACC3 requires Aurora-A-dependent stabilization of a cryptic α-helix.

Burgess SG, Mukherjee M, Sabir S, Joseph N, Gutiérrez-Caballero C, Richards MW, Huguenin-Dezot N, Chin JW, Kennedy EJ, Pfuhl M, Royle SJ, Gergely F, Bayliss R.

EMBO J. 2018 Mar 6. pii: e97902. doi: 10.15252/embj.201797902. [Epub ahead of print]


New tools for "hot-wiring" clathrin-mediated endocytosis with temporal and spatial precision.

Wood LA, Larocque G, Clarke NI, Sarkar S, Royle SJ.

J Cell Biol. 2017 Dec 4;216(12):4351-4365. doi: 10.1083/jcb.201702188. Epub 2017 Sep 27.


FGFR3-TACC3 cancer gene fusions cause mitotic defects by removal of endogenous TACC3 from the mitotic spindle.

Sarkar S, Ryan EL, Royle SJ.

Open Biol. 2017 Aug;7(8). pii: 170080. doi: 10.1098/rsob.170080.


Congressing kinetochores progressively load Ska complexes to prevent force-dependent detachment.

Auckland P, Clarke NI, Royle SJ, McAinsh AD.

J Cell Biol. 2017 Jun 5;216(6):1623-1639. doi: 10.1083/jcb.201607096. Epub 2017 May 11.


Microtubule organization within mitotic spindles revealed by serial block face scanning electron microscopy and image analysis.

Nixon FM, Honnor TR, Clarke NI, Starling GP, Beckett AJ, Johansen AM, Brettschneider JA, Prior IA, Royle SJ.

J Cell Sci. 2017 May 15;130(10):1845-1855. doi: 10.1242/jcs.203877. Epub 2017 Apr 7.


The mesh is a network of microtubule connectors that stabilizes individual kinetochore fibers of the mitotic spindle.

Nixon FM, Gutiérrez-Caballero C, Hood FE, Booth DG, Prior IA, Royle SJ.

Elife. 2015 Jun 19;4. doi: 10.7554/eLife.07635.


A novel disorder reveals clathrin heavy chain-22 is essential for human pain and touch development.

Nahorski MS, Al-Gazali L, Hertecant J, Owen DJ, Borner GH, Chen YC, Benn CL, Carvalho OP, Shaikh SS, Phelan A, Robinson MS, Royle SJ, Woods CG.

Brain. 2015 Aug;138(Pt 8):2147-60. doi: 10.1093/brain/awv149. Epub 2015 Jun 11.


Hsp72 is targeted to the mitotic spindle by Nek6 to promote K-fiber assembly and mitotic progression.

O'Regan L, Sampson J, Richards MW, Knebel A, Roth D, Hood FE, Straube A, Royle SJ, Bayliss R, Fry AM.

J Cell Biol. 2015 May 11;209(3):349-58. doi: 10.1083/jcb.201409151. Epub 2015 May 4.


Zero tolerance: amphipathic helices in endocytosis.

Wood LA, Royle SJ.

Dev Cell. 2015 Apr 20;33(2):119-20. doi: 10.1016/j.devcel.2015.04.007.


TACC3-ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation.

Gutiérrez-Caballero C, Burgess SG, Bayliss R, Royle SJ.

Biol Open. 2015 Jan 16;4(2):170-9. doi: 10.1242/bio.201410843.


Super-duper resolution imaging of mitotic microtubules.

Royle SJ.

Nat Rev Mol Cell Biol. 2015 Feb;16(2):67. doi: 10.1038/nrm3937. Epub 2015 Jan 5. No abstract available.


Presynaptic clathrin levels are a limiting factor for synaptic transmission.

López-Murcia FJ, Royle SJ, Llobet A.

J Neurosci. 2014 Jun 18;34(25):8618-29. doi: 10.1523/JNEUROSCI.5081-13.2014.


Non-specificity of Pitstop 2 in clathrin-mediated endocytosis.

Willox AK, Sahraoui YM, Royle SJ.

Biol Open. 2014 Apr 4;3(5):326-31. doi: 10.1242/bio.20147955.


An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis.

Kaur S, Fielding AB, Gassner G, Carter NJ, Royle SJ.

Elife. 2014 Feb 18;3:e00829. doi: 10.7554/eLife.00829.


Studying kinetochore-fiber ultrastructure using correlative light-electron microscopy.

Booth DG, Cheeseman LP, Prior IA, Royle SJ.

Methods Cell Biol. 2013;115:327-342. doi: 10.1016/B978-0-12-407757-7.00020-7.


Protein adaptation: mitotic functions for membrane trafficking proteins.

Royle SJ.

Nat Rev Mol Cell Biol. 2013 Sep;14(9):592-9. doi: 10.1038/nrm3641. Epub 2013 Aug 14. Review.


Coordination of adjacent domains mediates TACC3-ch-TOG-clathrin assembly and mitotic spindle binding.

Hood FE, Williams SJ, Burgess SG, Richards MW, Roth D, Straube A, Pfuhl M, Bayliss R, Royle SJ.

J Cell Biol. 2013 Aug 5;202(3):463-78. doi: 10.1083/jcb.201211127.


Specific removal of TACC3-ch-TOG-clathrin at metaphase deregulates kinetochore fiber tension.

Cheeseman LP, Harry EF, McAinsh AD, Prior IA, Royle SJ.

J Cell Sci. 2013 May 1;126(Pt 9):2102-13. doi: 10.1242/jcs.124834. Epub 2013 Mar 26.


Mitotic inhibition of clathrin-mediated endocytosis.

Fielding AB, Royle SJ.

Cell Mol Life Sci. 2013 Sep;70(18):3423-33. doi: 10.1007/s00018-012-1250-8. Epub 2013 Jan 11. Review.


Stonin 2 is a major adaptor protein for clathrin-mediated synaptic vesicle retrieval.

Willox AK, Royle SJ.

Curr Biol. 2012 Aug 7;22(15):1435-9. doi: 10.1016/j.cub.2012.05.048. Epub 2012 Jun 21.


Clathrin-mediated endocytosis is inhibited during mitosis.

Fielding AB, Willox AK, Okeke E, Royle SJ.

Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6572-7. doi: 10.1073/pnas.1117401109. Epub 2012 Apr 9.


The role of clathrin in mitotic spindle organisation.

Royle SJ.

J Cell Sci. 2012 Jan 1;125(Pt 1):19-28. doi: 10.1242/jcs.094607. Review.


Constitutive clathrin-mediated endocytosis of CTLA-4 persists during T cell activation.

Qureshi OS, Kaur S, Hou TZ, Jeffery LE, Poulter NS, Briggs Z, Kenefeck R, Willox AK, Royle SJ, Rappoport JZ, Sansom DM.

J Biol Chem. 2012 Mar 16;287(12):9429-40. doi: 10.1074/jbc.M111.304329. Epub 2012 Jan 19.


Aurora A kinase activity is required for localization of TACC3/ch-TOG/clathrin inter-microtubule bridges.

Cheeseman LP, Booth DG, Hood FE, Prior IA, Royle SJ.

Commun Integr Biol. 2011 Jul;4(4):409-12. doi: 10.4161/cib.4.4.15250. Epub 2011 Jul 1.


Functional analysis of interaction sites on the N-terminal domain of clathrin heavy chain.

Willox AK, Royle SJ.

Traffic. 2012 Jan;13(1):70-81. doi: 10.1111/j.1600-0854.2011.01289.x. Epub 2011 Oct 20.


Pulling it together: The mitotic function of TACC3.

Hood FE, Royle SJ.

Bioarchitecture. 2011 May;1(3):105-109.


Mitotic moonlighting functions for membrane trafficking proteins.

Royle SJ.

Traffic. 2011 Jul;12(7):791-8. doi: 10.1111/j.1600-0854.2011.01184.x. Epub 2011 Mar 24. Review.


Clathrin heavy chain gene fusions expressed in human cancers: analysis of cellular functions.

Blixt MK, Royle SJ.

Traffic. 2011 Jun;12(6):754-61. doi: 10.1111/j.1600-0854.2011.01183.x. Epub 2011 Mar 24.


A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging.

Booth DG, Hood FE, Prior IA, Royle SJ.

EMBO J. 2011 Mar 2;30(5):906-19. doi: 10.1038/emboj.2011.15. Epub 2011 Feb 4.


Clathrin-mediated endocytosis at the synaptic terminal: bridging the gap between physiology and molecules.

Royle SJ, Lagnado L.

Traffic. 2010 Dec;11(12):1489-97. doi: 10.1111/j.1600-0854.2010.01104.x. Review.


Comment on "The dynamic control of kiss-and-run and vesicular reuse probed with single nanoparticles".

Granseth B, Odermatt B, Royle SJ, Lagnado L.

Science. 2009 Sep 18;325(5947):1499; author reply 1499. doi: 10.1126/science.1175790.


Functional equivalence of the clathrin heavy chains CHC17 and CHC22 in endocytosis and mitosis.

Hood FE, Royle SJ.

J Cell Sci. 2009 Jul 1;122(Pt 13):2185-90. doi: 10.1242/jcs.046177. Epub 2009 Jun 9.


Imaging phluorin-based probes at hippocampal synapses.

Royle SJ, Granseth B, Odermatt B, Derevier A, Lagnado L.

Methods Mol Biol. 2008;457:293-303.


Clathrin-mediated endocytosis: the physiological mechanism of vesicle retrieval at hippocampal synapses.

Granseth B, Odermatt B, Royle SJ, Lagnado L.

J Physiol. 2007 Dec 15;585(Pt 3):681-6. Epub 2007 Jun 28. Review.


Clathrin-mediated endocytosis is the dominant mechanism of vesicle retrieval at hippocampal synapses.

Granseth B, Odermatt B, Royle SJ, Lagnado L.

Neuron. 2006 Sep 21;51(6):773-86.


Trimerisation is important for the function of clathrin at the mitotic spindle.

Royle SJ, Lagnado L.

J Cell Sci. 2006 Oct 1;119(Pt 19):4071-8. Epub 2006 Sep 12.


The cellular functions of clathrin.

Royle SJ.

Cell Mol Life Sci. 2006 Aug;63(16):1823-32. Review.


Non-canonical YXXGPhi endocytic motifs: recognition by AP2 and preferential utilization in P2X4 receptors.

Royle SJ, Qureshi OS, Bobanović LK, Evans PR, Owen DJ, Murrell-Lagnado RD.

J Cell Sci. 2005 Jul 15;118(Pt 14):3073-80. Epub 2005 Jun 28.


Clathrin is required for the function of the mitotic spindle.

Royle SJ, Bright NA, Lagnado L.

Nature. 2005 Apr 28;434(7037):1152-7.


Endocytosis at the synaptic terminal.

Royle SJ, Lagnado L.

J Physiol. 2003 Dec 1;553(Pt 2):345-55. Epub 2003 Sep 8. Review.


Constitutive cycling: a general mechanism to regulate cell surface proteins.

Royle SJ, Murrell-Lagnado RD.

Bioessays. 2003 Jan;25(1):39-46. Review.


Identification of a non-canonical tyrosine-based endocytic motif in an ionotropic receptor.

Royle SJ, Bobanović LK, Murrell-Lagnado RD.

J Biol Chem. 2002 Sep 20;277(38):35378-85. Epub 2002 Jul 8.


P2X receptor trafficking in neurons is subunit specific.

Bobanovic LK, Royle SJ, Murrell-Lagnado RD.

J Neurosci. 2002 Jun 15;22(12):4814-24.


Behavioural analysis and susceptibility to CNS injury of four inbred strains of mice.

Royle SJ, Collins FC, Rupniak HT, Barnes JC, Anderson R.

Brain Res. 1999 Jan 23;816(2):337-49.


Supplemental Content

Loading ...
Support Center