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Items: 1 to 50 of 270

1.

Less immune activation following social stress in rural vs. urban participants raised with regular or no animal contact, respectively.

Böbel TS, Hackl SB, Langgartner D, Jarczok MN, Rohleder N, Rook GA, Lowry CA, Gündel H, Waller C, Reber SO.

Proc Natl Acad Sci U S A. 2018 May 15;115(20):5259-5264. doi: 10.1073/pnas.1719866115. Epub 2018 Apr 30.

2.

The Microbiome of the Built Environment and Human Behavior: Implications for Emotional Health and Well-Being in Postmodern Western Societies.

Stamper CE, Hoisington AJ, Gomez OM, Halweg-Edwards AL, Smith DG, Bates KL, Kinney KA, Postolache TT, Brenner LA, Rook GA, Lowry CA.

Int Rev Neurobiol. 2016;131:289-323. doi: 10.1016/bs.irn.2016.07.006. Epub 2016 Sep 6. Review.

PMID:
27793224
3.

The Microbiota, Immunoregulation, and Mental Health: Implications for Public Health.

Lowry CA, Smith DG, Siebler PH, Schmidt D, Stamper CE, Hassell JE Jr, Yamashita PS, Fox JH, Reber SO, Brenner LA, Hoisington AJ, Postolache TT, Kinney KA, Marciani D, Hernandez M, Hemmings SM, Malan-Muller S, Wright KP, Knight R, Raison CL, Rook GA.

Curr Environ Health Rep. 2016 Sep;3(3):270-86. doi: 10.1007/s40572-016-0100-5. Review.

4.

Time to abandon the hygiene hypothesis: new perspectives on allergic disease, the human microbiome, infectious disease prevention and the role of targeted hygiene.

Bloomfield SF, Rook GA, Scott EA, Shanahan F, Stanwell-Smith R, Turner P.

Perspect Public Health. 2016 Jul;136(4):213-24. doi: 10.1177/1757913916650225.

5.

Immunization with a heat-killed preparation of the environmental bacterium Mycobacterium vaccae promotes stress resilience in mice.

Reber SO, Siebler PH, Donner NC, Morton JT, Smith DG, Kopelman JM, Lowe KR, Wheeler KJ, Fox JH, Hassell JE Jr, Greenwood BN, Jansch C, Lechner A, Schmidt D, Uschold-Schmidt N, Füchsl AM, Langgartner D, Walker FR, Hale MW, Lopez Perez G, Van Treuren W, González A, Halweg-Edwards AL, Fleshner M, Raison CL, Rook GA, Peddada SD, Knight R, Lowry CA.

Proc Natl Acad Sci U S A. 2016 May 31;113(22):E3130-9. doi: 10.1073/pnas.1600324113. Epub 2016 May 16.

6.

Microbiota, immunoregulatory old friends and psychiatric disorders.

Rook GA, Raison CL, Lowry CA.

Adv Exp Med Biol. 2014;817:319-56. doi: 10.1007/978-1-4939-0897-4_15. Review.

PMID:
24997041
7.

Hygiene and other early childhood influences on the subsequent function of the immune system.

Rook GA, Lowry CA, Raison CL.

Brain Res. 2015 Aug 18;1617:47-62. doi: 10.1016/j.brainres.2014.04.004. Epub 2014 Apr 13. Review.

8.

Microbial 'Old Friends', immunoregulation and stress resilience.

Rook GA, Lowry CA, Raison CL.

Evol Med Public Health. 2013 Jan;2013(1):46-64. doi: 10.1093/emph/eot004. Epub 2013 Apr 9.

9.

Childhood microbial experience, immunoregulation, inflammation and adult susceptibility to psychosocial stressors and depression in rich and poor countries.

Rook GA, Raison CL, Lowry CA.

Evol Med Public Health. 2013 Jan;2013(1):14-7. doi: 10.1093/emph/eos005. Epub 2012 Nov 18. No abstract available.

10.

Microbial 'old friends', immunoregulation and socioeconomic status.

Rook GA, Raison CL, Lowry CA.

Clin Exp Immunol. 2014 Jul;177(1):1-12. doi: 10.1111/cei.12269. Review.

11.

Regulation of the immune system by biodiversity from the natural environment: an ecosystem service essential to health.

Rook GA.

Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18360-7. doi: 10.1073/pnas.1313731110. Epub 2013 Oct 23. Review.

12.

Regulation of inflammation by interleukin-4: a review of "alternatives".

Luzina IG, Keegan AD, Heller NM, Rook GA, Shea-Donohue T, Atamas SP.

J Leukoc Biol. 2012 Oct;92(4):753-64. doi: 10.1189/jlb.0412214. Epub 2012 Jul 10. Review.

13.

Pathways underlying afferent signaling of bronchopulmonary immune activation to the central nervous system.

Hale MW, Rook GA, Lowry CA.

Chem Immunol Allergy. 2012;98:118-41. doi: 10.1159/000336505. Epub 2012 Jun 26. Review.

PMID:
22767061
14.

Can we vaccinate against depression?

Rook GA, Raison CL, Lowry CA.

Drug Discov Today. 2012 May;17(9-10):451-8. doi: 10.1016/j.drudis.2012.03.018. Epub 2012 Apr 7. Review.

PMID:
22507593
15.

Hygiene hypothesis and autoimmune diseases.

Rook GA.

Clin Rev Allergy Immunol. 2012 Feb;42(1):5-15. doi: 10.1007/s12016-011-8285-8. Review.

PMID:
22090147
16.

Hygiene and other early childhood influences on the subsequent function of the immune system.

Rook GA.

Dig Dis. 2011;29(2):144-53. doi: 10.1159/000323877. Epub 2011 Jul 5. Review.

PMID:
21734378
17.

Infection, immunoregulation, and cancer.

Rook GA, Dalgleish A.

Immunol Rev. 2011 Mar;240(1):141-59. doi: 10.1111/j.1600-065X.2010.00987.x. Review.

PMID:
21349092
18.

CCL2, CCL18 and sIL-4R in renal, meningeal and pulmonary TB; a 2 year study of patients and contacts.

Mendez A, Hernandez-Pando R, Contreras S, Aguilar D, Rook GA.

Tuberculosis (Edinb). 2011 Mar;91(2):140-5. doi: 10.1016/j.tube.2010.12.008. Epub 2011 Jan 19.

PMID:
21251883
19.

Lymphocytes in neuroprotection, cognition and emotion: is intolerance really the answer?

Rook GA, Lowry CA, Raison CL.

Brain Behav Immun. 2011 May;25(4):591-601. doi: 10.1016/j.bbi.2010.12.005. Epub 2010 Dec 16. Review.

PMID:
21167931
20.

Inflammation, sanitation, and consternation: loss of contact with coevolved, tolerogenic microorganisms and the pathophysiology and treatment of major depression.

Raison CL, Lowry CA, Rook GA.

Arch Gen Psychiatry. 2010 Dec;67(12):1211-24. doi: 10.1001/archgenpsychiatry.2010.161. Review.

21.
22.

An assessment of air as a source of DNA contamination encountered when performing PCR.

Witt N, Rodger G, Vandesompele J, Benes V, Zumla A, Rook GA, Huggett JF.

J Biomol Tech. 2009 Dec;20(5):236-40.

23.

Advances in immunotherapy for tuberculosis treatment.

Churchyard GJ, Kaplan G, Fallows D, Wallis RS, Onyebujoh P, Rook GA.

Clin Chest Med. 2009 Dec;30(4):769-82, ix. doi: 10.1016/j.ccm.2009.08.009. Review.

PMID:
19925966
24.

Tuberculosis due to high-dose challenge in partially immune individuals: a problem for vaccination?

Rook GA, Hernández-Pando R, Zumla A.

J Infect Dis. 2009 Mar 1;199(5):613-8. doi: 10.1086/596654.

PMID:
19199549
25.
26.

Orally administered Mycobacterium vaccae modulates expression of immunoregulatory molecules in BALB/c mice with pulmonary tuberculosis.

Hernández-Pando R, Aguilar D, Orozco H, Cortez Y, Brunet LR, Rook GA.

Clin Vaccine Immunol. 2008 Nov;15(11):1730-6. doi: 10.1128/CVI.00286-08. Epub 2008 Sep 30.

27.

The changing microbial environment and chronic inflammatory disorders.

Rook GA.

Allergy Asthma Clin Immunol. 2008 Sep 15;4(3):117-24. doi: 10.1186/1710-1492-4-3-117. Epub 2008 Sep 15.

28.

Gene expression of IL17 and IL23 in the lungs of patients with active tuberculosis.

Dheda K, Chang JS, Lala S, Huggett JF, Zumla A, Rook GA.

Thorax. 2008 Jun;63(6):566-8. doi: 10.1136/thx.2007.092205. No abstract available.

PMID:
18511642
29.

The hygiene hypothesis and psychiatric disorders.

Rook GA, Lowry CA.

Trends Immunol. 2008 Apr;29(4):150-8. doi: 10.1016/j.it.2008.01.002. Epub 2008 Mar 6.

PMID:
18328783
30.

Steroid metabolism and immunity: therapeutic implications.

Rook GA, Baker R, Zumla A.

BioDrugs. 1997 Sep;8(3):157-63.

PMID:
18020506
31.

The pathogen recognition sensor, NOD2, is variably expressed in patients with pulmonary tuberculosis.

Lala S, Dheda K, Chang JS, Huggett JF, Kim LU, Johnson MA, Rook GA, Keshav S, Zumla A.

BMC Infect Dis. 2007 Aug 16;7:96.

32.

The hygiene hypothesis and the increasing prevalence of chronic inflammatory disorders.

Rook GA.

Trans R Soc Trop Med Hyg. 2007 Nov;101(11):1072-4. Epub 2007 Jul 9. Review.

PMID:
17619029
33.

Immunotherapeutics for tuberculosis in experimental animals: is there a common pathway activated by effective protocols?

Rook GA, Lowrie DB, Hernàndez-Pando R.

J Infect Dis. 2007 Jul 15;196(2):191-8. Epub 2007 Jun 5. Review.

PMID:
17570105
34.

Mycobacteria and allergies.

Rook GA, Hamelmann E, Brunet LR.

Immunobiology. 2007;212(6):461-73. Epub 2007 Apr 17. Review.

PMID:
17544831
35.

Th2 cytokines in susceptibility to tuberculosis.

Rook GA.

Curr Mol Med. 2007 May;7(3):327-37. Review.

PMID:
17504117
36.

FOXP3 gene expression in a tuberculosis case contact study.

Burl S, Hill PC, Jeffries DJ, Holland MJ, Fox A, Lugos MD, Adegbola RA, Rook GA, Zumla A, McAdam KP, Brookes RH.

Clin Exp Immunol. 2007 Jul;149(1):117-22. Epub 2007 Apr 26.

37.

Interpretation of Mycobacterium tuberculosis antigen-specific IFN-gamma release assays (T-SPOT.TB) and factors that may modulate test results.

Dheda K, Pooran A, Pai M, Miller RF, Lesley K, Booth HL, Scott GM, Akbar AN, Zumla A, Rook GA.

J Infect. 2007 Aug;55(2):169-73. Epub 2007 Apr 19.

PMID:
17448540
38.

Stop TB: a long way to go, but new twists & turns in the science.

Rook GA.

Indian J Med Res. 2007 Feb;125(2):109-11. No abstract available.

PMID:
17431278
39.

Identification of an immune-responsive mesolimbocortical serotonergic system: potential role in regulation of emotional behavior.

Lowry CA, Hollis JH, de Vries A, Pan B, Brunet LR, Hunt JR, Paton JF, van Kampen E, Knight DM, Evans AK, Rook GA, Lightman SL.

Neuroscience. 2007 May 11;146(2):756-72. Epub 2007 Mar 23.

40.

The stability of mRNA encoding IL-4 is increased in pulmonary tuberculosis, while stability of mRNA encoding the antagonistic splice variant, IL-4delta2, is not.

Dheda K, Chang JS, Huggett JF, Kim LU, Johnson MA, Zumla A, Rook GA.

Tuberculosis (Edinb). 2007 May;87(3):237-41. Epub 2006 Dec 29.

PMID:
17196882
41.

Endocrine and cytokine responses in humans with pulmonary tuberculosis.

Rook GA.

Brain Behav Immun. 2007 Feb;21(2):169-70. Epub 2006 Sep 20. No abstract available.

PMID:
16989979
42.

Killed Mycobacterium vaccae suspension in children with moderate-to-severe atopic dermatitis: a randomized, double-blind, placebo-controlled trial.

Berth-Jones J, Arkwright PD, Marasovic D, Savani N, Aldridge CR, Leech SN, Morgan C, Clark SM, Ogilvie S, Chopra S, Harper JI, Smith CH, Rook GA, Friedmann PS.

Clin Exp Allergy. 2006 Sep;36(9):1115-21.

PMID:
16961710
43.

Tryptophan metabolism in the central nervous system: medical implications.

Ruddick JP, Evans AK, Nutt DJ, Lightman SL, Rook GA, Lowry CA.

Expert Rev Mol Med. 2006 Aug 31;8(20):1-27. Review.

PMID:
16942634
44.

Expression of IL-4 mRNA in peripheral blood mononuclear cells from normal donors in relation to expression of TLR2.

Chang JS, Dheda K, Huggett JF, Kim LU, Zumla A, Rook GA.

Immunol Lett. 2006 Aug 15;106(2):194-7. Epub 2006 Jun 27.

PMID:
16919700
45.

Mechanisms of disease: the hygiene hypothesis revisited.

Guarner F, Bourdet-Sicard R, Brandtzaeg P, Gill HS, McGuirk P, van Eden W, Versalovic J, Weinstock JV, Rook GA.

Nat Clin Pract Gastroenterol Hepatol. 2006 May;3(5):275-84. Review.

PMID:
16673007
46.

Comments on the new analysis of the Chingleput BCG trial.

Rook GA, Kim LU.

Indian J Med Res. 2006 Feb;123(2):103-6. No abstract available.

PMID:
16575105
47.

Immune systems in developed and developing countries; implications for the design of vaccines that will work where BCG does not.

Rook GA, Dheda K, Zumla A.

Tuberculosis (Edinb). 2006 May-Jul;86(3-4):152-62. Epub 2006 Feb 28. Review.

PMID:
16510309
48.
49.

Smoking and tuberculosis: the epidemiological association and immunopathogenesis.

Davies PD, Yew WW, Ganguly D, Davidow AL, Reichman LB, Dheda K, Rook GA.

Trans R Soc Trop Med Hyg. 2006 Apr;100(4):291-8. Epub 2005 Dec 1. Review.

PMID:
16325875
50.

Performance of a T-cell-based diagnostic test for tuberculosis infection in HIV-infected individuals is independent of CD4 cell count.

Dheda K, Lalvani A, Miller RF, Scott G, Booth H, Johnson MA, Zumla A, Rook GA.

AIDS. 2005 Nov 18;19(17):2038-41.

PMID:
16260914

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