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Inducible Genome Editing with Conditional CRISPR/Cas9 Mice.

Katigbak A, Robert F, Paquet M, Pelletier J.

G3 (Bethesda). 2018 Mar 8. pii: g3.300327.2017. doi: 10.1534/g3.117.300327. [Epub ahead of print]


Archean kerogen as a new tracer of atmospheric evolution: Implications for dating the widespread nature of early life.

Bekaert DV, Broadley MW, Delarue F, Avice G, Robert F, Marty B.

Sci Adv. 2018 Feb 28;4(2):eaar2091. doi: 10.1126/sciadv.aar2091. eCollection 2018 Feb.


Osmoregulatory adaptations during lactation: Thirst, arginine vasopressin and plasma osmolality responses.

Amabebe E, Robert FO, Obika LFO.

Niger J Physiol Sci. 2017 Dec 30;32(2):109-116.


Percutaneous endoscopic gastrostomy (PEG) versus radiologically inserted gastrostomy (RIG): A comparison of outcomes at an Australian teaching hospital.

Vidhya C, Phoebe D, Dhina C, Jayne S, Robert F.

Clin Nutr ESPEN. 2018 Feb;23:136-140. doi: 10.1016/j.clnesp.2017.10.014. Epub 2017 Nov 27.


CRISPR/Cas9 Editing to Facilitate and Expand Drug Discovery.

Robert F, Huang S, Pelletier J.

Curr Gene Ther. 2017;17(4):275-285. doi: 10.2174/1566523217666171121164615.


Investigation of the Geochemical Preservation of ca. 3.0 Ga Permineralized and Encapsulated Microfossils by Nanoscale Secondary Ion Mass Spectrometry.

Delarue F, Robert F, Sugitani K, Tartèse R, Duhamel R, Derenne S.

Astrobiology. 2017 Dec;17(12):1192-1202. doi: 10.1089/ast.2016.1531. Epub 2017 Oct 23.


Spt6 Gets in the Way of Polycomb to Promote ESC Pluripotency.

Robert F.

Mol Cell. 2017 Oct 19;68(2):263-264. doi: 10.1016/j.molcel.2017.10.005.


TC-PTP regulates the IL-7 transcriptional response during murine early T cell development.

Pike KA, Hatzihristidis T, Bussières-Marmen S, Robert F, Desai N, Miranda-Saavedra D, Pelletier J, Tremblay ML.

Sci Rep. 2017 Oct 16;7(1):13275. doi: 10.1038/s41598-017-13673-w.


Bidirectional terminators: an underestimated aspect of gene regulation.

Robert F.

Curr Genet. 2018 Apr;64(2):389-391. doi: 10.1007/s00294-017-0763-y. Epub 2017 Oct 10. Review.


Erratum: Molecular preservation of 1.88 Ga Gunflint organic microfossils as a function of temperature and mineralogy.

Alleon J, Bernard S, Le Guillou C, Marin-Carbonne J, Pont S, Beyssac O, McKeegan KD, Robert F.

Nat Commun. 2017 Aug 14;8:16147. doi: 10.1038/ncomms16147.


Successful Electroconvulsive Therapy for a Patient With McArdle Disease.

Robert FX, Modica P, Lagrange G, Delahaye D, Prima F, Vilcoq P, Albanese J, Lançon C, Richieri R.

J ECT. 2017 Dec;33(4):e36-e37. doi: 10.1097/YCT.0000000000000440. No abstract available.


The Mediator Complex: At the Nexus of RNA Polymerase II Transcription.

Jeronimo C, Robert F.

Trends Cell Biol. 2017 Oct;27(10):765-783. doi: 10.1016/j.tcb.2017.07.001. Epub 2017 Aug 1. Review.


Analysis of the Optimum Gain of a High-Pass L-Matching Network for Rectennas.

Gasulla M, Jordana J, Robert FJ, Berenguer J.

Sensors (Basel). 2017 Jul 25;17(8). pii: E1712. doi: 10.3390/s17081712.


Visible-Light-Mediated Addition of Phenacyl Bromides onto Cyclopropenes.

Dange NS, Hussain Jatoi A, Robert F, Landais Y.

Org Lett. 2017 Jul 7;19(13):3652-3655. doi: 10.1021/acs.orglett.7b01651. Epub 2017 Jun 28.


A pilot study of zoledronic acid in the treatment of patients with advanced malignant pleural mesothelioma.

Jamil MO, Jerome MS, Miley D, Selander KS, Robert F.

Lung Cancer (Auckl). 2017 Jun 12;8:39-44. doi: 10.2147/LCTT.S135802. eCollection 2017.


Organic molecular heterogeneities can withstand diagenesis.

Alleon J, Bernard S, Le Guillou C, Daval D, Skouri-Panet F, Kuga M, Robert F.

Sci Rep. 2017 May 4;7(1):1508. doi: 10.1038/s41598-017-01612-8.


Places and social contexts associated with simultaneous use of alcohol, tobacco and marijuana among young adults.

Lipperman-Kreda S, Paschall MJ, Robert F S, Morrison CN.

Drug Alcohol Rev. 2018 Feb;37(2):188-195. doi: 10.1111/dar.12537. Epub 2017 Apr 19.


Bidirectional terminators in Saccharomyces cerevisiae prevent cryptic transcription from invading neighboring genes.

Uwimana N, Collin P, Jeronimo C, Haibe-Kains B, Robert F.

Nucleic Acids Res. 2017 Jun 20;45(11):6417-6426. doi: 10.1093/nar/gkx242.


Pilot phase II study of metronomic chemotherapy in combination with bevacizumab in patients with advanced non-squamous non-small cell lung cancer.

Jones BS, Jerome MS, Miley D, Jackson BE, DeShazo MR, Reddy VV, Singh KP, Brown OC, Robert F.

Lung Cancer. 2017 Apr;106:125-130. doi: 10.1016/j.lungcan.2017.02.004. Epub 2017 Feb 9.


Risk factors associated with the different categories of piglet perinatal mortality in French farms.

Pandolfi F, Edwards SA, Robert F, Kyriazakis I.

Prev Vet Med. 2017 Feb 1;137(Pt A):1-12. doi: 10.1016/j.prevetmed.2016.12.005. Epub 2016 Dec 7.


Hydrogen isotope fractionation in methane plasma.

Robert F, Derenne S, Lombardi G, Hassouni K, Michau A, Reinhardt P, Duhamel R, Gonzalez A, Biron K.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):870-874. doi: 10.1073/pnas.1615767114. Epub 2017 Jan 17.


Free-Radical Carbocyanation of Olefins.

Hassan H, Pirenne V, Wissing M, Khiar C, Hussain A, Robert F, Landais Y.

Chemistry. 2017 Apr 3;23(19):4651-4658. doi: 10.1002/chem.201605946. Epub 2017 Mar 15.


A CRISPR/Cas9 Functional Screen Identifies Rare Tumor Suppressors.

Katigbak A, Cencic R, Robert F, Sénécha P, Scuoppo C, Pelletier J.

Sci Rep. 2016 Dec 16;6:38968. doi: 10.1038/srep38968.


ORAL02.01: Safety and Efficacy of Single-Agent Rovalpituzumab Tesirine, a DLL3-Targeted ADC, in Recurrent or Refractory SCLC: Topic: Medical Oncology.

Bauer TM, Spigel D, Ready N, Morgensztern D, Glisson BS, Byers LA, Burris H, Robert F, Strickland DK, Pietanza MC, Govindan R, Dylla SJ, Peng S, Rudin C.

J Thorac Oncol. 2016 Nov;11(11S):S252-S253. doi: 10.1016/j.jtho.2016.09.010. Epub 2016 Oct 28. No abstract available.


Free-Radical Carbo-Alkenylation of Olefins: Scope, Limitations and Mechanistic Insights.

Beniazza R, Liautard V, Poittevin C, Ovadia B, Mohammed S, Robert F, Landais Y.

Chemistry. 2017 Feb 16;23(10):2439-2447. doi: 10.1002/chem.201605043. Epub 2017 Jan 23.


Free-Radical Carbocyanation of Cyclopropenes: Stereocontrolled Access to All-Carbon Quaternary Stereocenters in Acyclic Systems.

Dange NS, Robert F, Landais Y.

Org Lett. 2016 Dec 2;18(23):6156-6159. Epub 2016 Nov 21.


Rovalpituzumab tesirine, a DLL3-targeted antibody-drug conjugate, in recurrent small-cell lung cancer: a first-in-human, first-in-class, open-label, phase 1 study.

Rudin CM, Pietanza MC, Bauer TM, Ready N, Morgensztern D, Glisson BS, Byers LA, Johnson ML, Burris HA 3rd, Robert F, Han TH, Bheddah S, Theiss N, Watson S, Mathur D, Vennapusa B, Zayed H, Lally S, Strickland DK, Govindan R, Dylla SJ, Peng SL, Spigel DR; SCRX16-001 investigators.

Lancet Oncol. 2017 Jan;18(1):42-51. doi: 10.1016/S1470-2045(16)30565-4. Epub 2016 Dec 5.


A Spiking Strategy for ChIP-chip Data Normalization in S. cerevisiae.

Jeronimo C, Robert F.

Methods Mol Biol. 2017;1528:211-227.


Combined Action of Histone Reader Modules Regulates NuA4 Local Acetyltransferase Function but Not Its Recruitment on the Genome.

Steunou AL, Cramet M, Rossetto D, Aristizabal MJ, Lacoste N, Drouin S, Côté V, Paquet E, Utley RT, Krogan N, Robert F, Kobor MS, Côté J.

Mol Cell Biol. 2016 Oct 28;36(22):2768-2781. Print 2016 Nov 15.


Tail and Kinase Modules Differently Regulate Core Mediator Recruitment and Function In Vivo.

Jeronimo C, Langelier MF, Bataille AR, Pascal JM, Pugh BF, Robert F.

Mol Cell. 2016 Nov 3;64(3):455-466. doi: 10.1016/j.molcel.2016.09.002. Epub 2016 Oct 20.


Phase I Results from a Study of Crizotinib in Combination with Erlotinib in Patients with Advanced Nonsquamous Non-Small Cell Lung Cancer.

Ou SI, Govindan R, Eaton KD, Otterson GA, Gutierrez ME, Mita AC, Argiris A, Brega NM, Usari T, Tan W, Ho SN, Robert F.

J Thorac Oncol. 2017 Jan;12(1):145-151. doi: 10.1016/j.jtho.2016.09.131. Epub 2016 Sep 30.


Threshold Levels of Gfi1 Maintain E2A Activity for B Cell Commitment via Repression of Id1.

Fraszczak J, Helness A, Chen R, Vadnais C, Robert F, Khandanpour C, Möröy T.

PLoS One. 2016 Jul 28;11(7):e0160344. doi: 10.1371/journal.pone.0160344. eCollection 2016.


Phase II study of a novel taxane (Cabazitaxel-XRP 6258) in previously treated advanced non-small cell lung cancer (NSCLC) patients.

Madan A, Jones BS, Bordoni R, Saleh MN, Jerome MS, Miley DK, Jackson BE, Robert F.

Cancer Chemother Pharmacol. 2016 Sep;78(3):509-15. doi: 10.1007/s00280-016-3088-5. Epub 2016 Jul 14.


Molecular preservation of 1.88 Ga Gunflint organic microfossils as a function of temperature and mineralogy.

Alleon J, Bernard S, Le Guillou C, Marin-Carbonne J, Pont S, Beyssac O, McKeegan KD, Robert F.

Nat Commun. 2016 Jun 17;7:11977. doi: 10.1038/ncomms11977. Erratum in: Nat Commun. 2017 Aug 14;8:16147.


Heterogeneous Nuclear Ribonucleoprotein L is required for the survival and functional integrity of murine hematopoietic stem cells.

Gaudreau MC, Grapton D, Helness A, Vadnais C, Fraszczak J, Shooshtarizadeh P, Wilhelm B, Robert F, Heyd F, Möröy T.

Sci Rep. 2016 Jun 7;6:27379. doi: 10.1038/srep27379.


Epigenetic therapy as a novel approach for GFI136N-associated murine/human AML.

Botezatu L, Michel LC, Helness A, Vadnais C, Makishima H, Hönes JM, Robert F, Vassen L, Thivakaran A, Al-Matary Y, Lams RF, Schütte J, Giebel B, Görgens A, Heuser M, Medyouf H, Maciejewski J, Dührsen U, Möröy T, Khandanpour C.

Exp Hematol. 2016 Aug;44(8):713-726.e14. doi: 10.1016/j.exphem.2016.05.004. Epub 2016 May 20.


Haploinsufficiency of the ESCRT Component HD-PTP Predisposes to Cancer.

Manteghi S, Gingras MC, Kharitidi D, Galarneau L, Marques M, Yan M, Cencic R, Robert F, Paquet M, Witcher M, Pelletier J, Pause A.

Cell Rep. 2016 May 31;15(9):1893-900. doi: 10.1016/j.celrep.2016.04.076. Epub 2016 May 19.


The Raman-Derived Carbonization Continuum: A Tool to Select the Best Preserved Molecular Structures in Archean Kerogens.

Delarue F, Rouzaud JN, Derenne S, Bourbin M, Westall F, Kremer B, Sugitani K, Deldicque D, Robert F.

Astrobiology. 2016 Jun;16(6):407-17. doi: 10.1089/ast.2015.1392. Epub 2016 May 17.


Histone chaperones FACT and Spt6 prevent histone variants from turning into histone deviants.

Jeronimo C, Robert F.

Bioessays. 2016 May;38(5):420-6. doi: 10.1002/bies.201500122. Epub 2016 Mar 15.


Free-radical Carbo-functionalization of Olefins Using Sulfonyl Derivatives.

Ovadia B, Robert F, Landais Y.

Chimia (Aarau). 2016;70(1-2):34-42. doi: 10.2533/chimia.2016.34.


The RNA Polymerase II CTD: The Increasing Complexity of a Low-Complexity Protein Domain.

Jeronimo C, Collin P, Robert F.

J Mol Biol. 2016 Jun 19;428(12):2607-2622. doi: 10.1016/j.jmb.2016.02.006. Epub 2016 Feb 12. Review.


Nocturnal oxygen therapy in patients with chronic heart failure and sleep apnea: a systematic review.

Bordier P, Lataste A, Hofmann P, Robert F, Bourenane G.

Sleep Med. 2016 Jan;17:149-57. doi: 10.1016/j.sleep.2015.10.017. Epub 2015 Dec 2. Review.


GFI1 as a novel prognostic and therapeutic factor for AML/MDS.

Hönes JM, Botezatu L, Helness A, Vadnais C, Vassen L, Robert F, Hergenhan SM, Thivakaran A, Schütte J, Al-Matary YS, Lams RF, Fraszscak J, Makishima H, Radivoyevitch T, Przychodzen B, da Conceição Castro SV, Görgens A, Giebel B, Klein-Hitpass L, Lennartz K, Heuser M, Thiede C, Ehninger G, Dührsen U, Maciejewski JP, Möröy T, Khandanpour C.

Leukemia. 2016 Jun;30(6):1237-45. doi: 10.1038/leu.2016.11. Epub 2016 Feb 5.


ASGPR-Mediated Uptake of Multivalent Glycoconjugates for Drug Delivery in Hepatocytes.

Monestier M, Charbonnier P, Gateau C, Cuillel M, Robert F, Lebrun C, Mintz E, Renaudet O, Delangle P.

Chembiochem. 2016 Apr 1;17(7):590-4. doi: 10.1002/cbic.201600023. Epub 2016 Mar 2.


Repression of p53-target gene Bbc3/PUMA by MYSM1 is essential for the survival of hematopoietic multipotent progenitors and contributes to stem cell maintenance.

Belle JI, Petrov JC, Langlais D, Robert F, Cencic R, Shen S, Pelletier J, Gros P, Nijnik A.

Cell Death Differ. 2016 May;23(5):759-75. doi: 10.1038/cdd.2015.140. Epub 2016 Jan 15.


PAM multiplicity marks genomic target sites as inhibitory to CRISPR-Cas9 editing.

Malina A, Cameron CJ, Robert F, Blanchette M, Dostie J, Pelletier J.

Nat Commun. 2015 Dec 8;6:10124. doi: 10.1038/ncomms10124.


Revisiting Plant Plasma Membrane Lipids in Tobacco: A Focus on Sphingolipids.

Cacas JL, Buré C, Grosjean K, Gerbeau-Pissot P, Lherminier J, Rombouts Y, Maes E, Bossard C, Gronnier J, Furt F, Fouillen L, Germain V, Bayer E, Cluzet S, Robert F, Schmitter JM, Deleu M, Lins L, Simon-Plas F, Mongrand S.

Plant Physiol. 2016 Jan;170(1):367-84. doi: 10.1104/pp.15.00564. Epub 2015 Oct 30.


The deuterium/hydrogen distribution in chondritic organic matter attests to early ionizing irradiation.

Laurent B, Roskosz M, Remusat L, Robert F, Leroux H, Vezin H, Depecker C, Nuns N, Lefebvre JM.

Nat Commun. 2015 Oct 13;6:8567. doi: 10.1038/ncomms9567.


Aggregate and Heatmap Representations of Genome-Wide Localization Data Using VAP, a Versatile Aggregate Profiler.

Brunelle M, Coulombe C, Poitras C, Robert MA, Markovits AN, Robert F, Jacques PÉ.

Methods Mol Biol. 2015;1334:273-98. doi: 10.1007/978-1-4939-2877-4_18.


Phase I/IIa study of sequential chemotherapy regimen of bendamustine/irinotecan followed by etoposide/carboplatin in untreated patients with extensive disease small cell lung cancer (EDSCLC).

Allendorf DJ, Bordoni RE, Grant SC, Saleh MN, Reddy VB, Jerome ML, Dixon PM, Miley DK, Singh KP, Robert F.

Cancer Chemother Pharmacol. 2015 Nov;76(5):949-55. doi: 10.1007/s00280-015-2869-6. Epub 2015 Sep 22.


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