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Items: 27

1.

Interleukin-10 Directly Inhibits CD8+ T Cell Function by Enhancing N-Glycan Branching to Decrease Antigen Sensitivity.

Smith LK, Boukhaled GM, Condotta SA, Mazouz S, Guthmiller JJ, Vijay R, Butler NS, Bruneau J, Shoukry NH, Krawczyk CM, Richer MJ.

Immunity. 2018 Feb 20;48(2):299-312.e5. doi: 10.1016/j.immuni.2018.01.006. Epub 2018 Jan 23.

PMID:
29396160
2.

The immune battlefield: The impact of inflammatory cytokines on CD8+ T-cell immunity.

Condotta SA, Richer MJ.

PLoS Pathog. 2017 Oct 26;13(10):e1006618. doi: 10.1371/journal.ppat.1006618. eCollection 2017 Oct. Review. No abstract available.

3.

Protein Tyrosine Phosphatase Inhibition Prevents Experimental Cerebral Malaria by Precluding CXCR3 Expression on T Cells.

Van Den Ham KM, Smith LK, Richer MJ, Olivier M.

Sci Rep. 2017 Jul 14;7(1):5478. doi: 10.1038/s41598-017-05609-1.

4.

Analysis of the T Cell Response to Zika Virus and Identification of a Novel CD8+ T Cell Epitope in Immunocompetent Mice.

Pardy RD, Rajah MM, Condotta SA, Taylor NG, Sagan SM, Richer MJ.

PLoS Pathog. 2017 Feb 23;13(2):e1006184. doi: 10.1371/journal.ppat.1006184. eCollection 2017 Feb.

5.

Serine Is an Essential Metabolite for Effector T Cell Expansion.

Ma EH, Bantug G, Griss T, Condotta S, Johnson RM, Samborska B, Mainolfi N, Suri V, Guak H, Balmer ML, Verway MJ, Raissi TC, Tsui H, Boukhaled G, Henriques da Costa S, Frezza C, Krawczyk CM, Friedman A, Manfredi M, Richer MJ, Hess C, Jones RG.

Cell Metab. 2017 Feb 7;25(2):482. doi: 10.1016/j.cmet.2017.01.014. No abstract available.

6.

Serine Is an Essential Metabolite for Effector T Cell Expansion.

Ma EH, Bantug G, Griss T, Condotta S, Johnson RM, Samborska B, Mainolfi N, Suri V, Guak H, Balmer ML, Verway MJ, Raissi TC, Tsui H, Boukhaled G, Henriques da Costa S, Frezza C, Krawczyk CM, Friedman A, Manfredi M, Richer MJ, Hess C, Jones RG.

Cell Metab. 2017 Feb 7;25(2):345-357. doi: 10.1016/j.cmet.2016.12.011. Epub 2017 Jan 19. Erratum in: Cell Metab. 2017 Feb 7;25(2):482.

7.

Zika Virus: Emergence, Phylogenetics, Challenges, and Opportunities.

Rajah MM, Pardy RD, Condotta SA, Richer MJ, Sagan SM.

ACS Infect Dis. 2016 Nov 11;2(11):763-772. Epub 2016 Oct 12. Review.

PMID:
27704772
8.

T Cell Fates Zipped Up: How the Bach2 Basic Leucine Zipper Transcriptional Repressor Directs T Cell Differentiation and Function.

Richer MJ, Lang ML, Butler NS.

J Immunol. 2016 Aug 15;197(4):1009-15. doi: 10.4049/jimmunol.1600847. Review.

9.

Exposure of Human CD4 T Cells to IL-12 Results in Enhanced TCR-Induced Cytokine Production, Altered TCR Signaling, and Increased Oxidative Metabolism.

Vacaflores A, Chapman NM, Harty JT, Richer MJ, Houtman JC.

PLoS One. 2016 Jun 9;11(6):e0157175. doi: 10.1371/journal.pone.0157175. eCollection 2016.

10.

Regulation of effector and memory CD8(+) T cell function by inflammatory cytokines.

Valbon SF, Condotta SA, Richer MJ.

Cytokine. 2016 Jun;82:16-23. doi: 10.1016/j.cyto.2015.11.013. Epub 2015 Dec 10. Review.

PMID:
26688544
11.

Enhancing Dendritic Cell-based Immunotherapy with IL-2/Monoclonal Antibody Complexes for Control of Established Tumors.

Kim MT, Richer MJ, Gross BP, Norian LA, Badovinac VP, Harty JT.

J Immunol. 2015 Nov 1;195(9):4537-44. doi: 10.4049/jimmunol.1501071. Epub 2015 Sep 25.

12.

Inflammatory IL-15 is required for optimal memory T cell responses.

Richer MJ, Pewe LL, Hancox LS, Hartwig SM, Varga SM, Harty JT.

J Clin Invest. 2015 Sep;125(9):3477-90. doi: 10.1172/JCI81261. Epub 2015 Aug 4.

13.

Pathogen-specific inflammatory milieux tune the antigen sensitivity of CD8(+) T cells by enhancing T cell receptor signaling.

Richer MJ, Nolz JC, Harty JT.

Immunity. 2013 Jan 24;38(1):140-52. doi: 10.1016/j.immuni.2012.09.017. Epub 2012 Dec 20.

14.

Selective pharmacological inhibition of phosphoinositide 3-kinase p110delta opposes the progression of autoimmune diabetes in non-obese diabetic (NOD) mice.

Durand CA, Richer MJ, Brenker K, Graves M, Shanina I, Choi K, Horwitz MS, Puri KD, Gold MR.

Autoimmunity. 2013 Feb;46(1):62-73. doi: 10.3109/08916934.2012.732130.

PMID:
23039284
15.

Immunomodulation of antigen presenting cells promotes natural regulatory T cells that prevent autoimmune diabetes in NOD mice.

Richer MJ, Lavallée DJ, Shanina I, Horwitz MS.

PLoS One. 2012;7(2):e31153. doi: 10.1371/journal.pone.0031153. Epub 2012 Feb 15.

16.

Probing CD8 T cell responses with Listeria monocytogenes infection.

Condotta SA, Richer MJ, Badovinac VP, Harty JT.

Adv Immunol. 2012;113:51-80. doi: 10.1016/B978-0-12-394590-7.00005-1. Review.

PMID:
22244579
17.

Preventing viral-induced type 1 diabetes.

Richer MJ, Horwitz MS.

Ann N Y Acad Sci. 2009 Sep;1173:487-92. doi: 10.1111/j.1749-6632.2009.04662.x. Review.

PMID:
19758190
18.

Coxsackievirus infection as an environmental factor in the etiology of type 1 diabetes.

Richer MJ, Horwitz MS.

Autoimmun Rev. 2009 Jun;8(7):611-5. doi: 10.1016/j.autrev.2009.02.006. Epub 2009 Feb 11. Review.

PMID:
19393207
19.

Toll-like receptor 3 signaling on macrophages is required for survival following coxsackievirus B4 infection.

Richer MJ, Lavallée DJ, Shanina I, Horwitz MS.

PLoS One. 2009;4(1):e4127. doi: 10.1371/journal.pone.0004127. Epub 2009 Jan 5.

20.

The innate immune response: an important partner in shaping coxsackievirus-mediated autoimmunity.

Richer MJ, Horwitz MS.

J Innate Immun. 2009;1(5):421-34. doi: 10.1159/000226247. Epub 2009 Jun 24. Review.

21.

Viral infections in the pathogenesis of autoimmune diseases: focus on type 1 diabetes.

Richer MJ, Horwitz MS.

Front Biosci. 2008 May 1;13:4241-57. Review.

PMID:
18508508
22.

Regulatory T-cells protect from type 1 diabetes after induction by coxsackievirus infection in the context of transforming growth factor-beta.

Richer MJ, Straka N, Fang D, Shanina I, Horwitz MS.

Diabetes. 2008 May;57(5):1302-11. doi: 10.2337/db07-1460. Epub 2008 Feb 11.

23.

Toll-like receptor 4-induced cytokine production circumvents protection conferred by TGF-beta in coxsackievirus-mediated autoimmune myocarditis.

Richer MJ, Fang D, Shanina I, Horwitz MS.

Clin Immunol. 2006 Dec;121(3):339-49. Epub 2006 Sep 11.

PMID:
16963319
24.
25.

The Spn4 gene of Drosophila encodes a potent furin-directed secretory pathway serpin.

Richer MJ, Keays CA, Waterhouse J, Minhas J, Hashimoto C, Jean F.

Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10560-5. Epub 2004 Jul 9.

26.

Serpin mechanism of hepatitis C virus nonstructural 3 (NS3) protease inhibition: induced fit as a mechanism for narrow specificity.

Richer MJ, Juliano L, Hashimoto C, Jean F.

J Biol Chem. 2004 Mar 12;279(11):10222-7. Epub 2003 Dec 29.

27.

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