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Items: 1 to 50 of 223

1.

The novel CXCR4 antagonist, PRX177561, reduces tumor cell proliferation and accelerates cancer stem cell differentiation in glioblastoma preclinical models.

Gravina GL, Mancini A, Colapietro A, Vitale F, Vetuschi A, Pompili S, Rossi G, Marampon F, Richardson PJ, Patient L, Patient L, Burbidge S, Festuccia C.

Tumour Biol. 2017 Jun;39(6):1010428317695528. doi: 10.1177/1010428317695528.

PMID:
28639900
2.

The brain-penetrating CXCR4 antagonist, PRX177561, increases the antitumor effects of bevacizumab and sunitinib in preclinical models of human glioblastoma.

Gravina GL, Mancini A, Marampon F, Colapietro A, Delle Monache S, Sferra R, Vitale F, Richardson PJ, Patient L, Burbidge S, Festuccia C.

J Hematol Oncol. 2017 Jan 5;10(1):5. doi: 10.1186/s13045-016-0377-8.

3.

CXCR4 and Glioblastoma.

Richardson PJ.

Anticancer Agents Med Chem. 2016;16(1):59-74. Review.

PMID:
26299663
4.

Using a rhabdomyosarcoma patient-derived xenograft to examine precision medicine approaches and model acquired resistance.

Monsma DJ, Cherba DM, Richardson PJ, Vance S, Rangarajan S, Dylewski D, Eugster E, Scott SB, Beuschel NL, Davidson PJ, Axtell R, Mitchell D, Lester EP, Junewick JJ, Webb CP, Monks NR.

Pediatr Blood Cancer. 2014 Sep;61(9):1570-7. doi: 10.1002/pbc.25039. Epub 2014 Mar 31.

PMID:
24687871
5.

The reflective statement: a new tool to assess resident learning.

Monaghan SF, Blakely AM, Richardson PJ, Miner TJ, Cioffi WG, Harrington DT.

J Surg Res. 2012 Dec;178(2):618-22. doi: 10.1016/j.jss.2012.07.034. Epub 2012 Aug 3.

6.

Inversion of plant dominance-diversity relationships along a latitudinal stress gradient.

Richardson PJ, MacDougall AS, Stanley AG, Kaye TN, Dunwiddie PW.

Ecology. 2012 Jun;93(6):1431-8.

PMID:
22834383
7.

Genomic characterization of explant tumorgraft models derived from fresh patient tumor tissue.

Monsma DJ, Monks NR, Cherba DM, Dylewski D, Eugster E, Jahn H, Srikanth S, Scott SB, Richardson PJ, Everts RE, Ishkin A, Nikolsky Y, Resau JH, Sigler R, Nickoloff BJ, Webb CP.

J Transl Med. 2012 Jun 18;10:125. doi: 10.1186/1479-5876-10-125.

8.

Piezochromism in nickel salicylaldoximato complexes: tuning crystal-field splitting with high pressure.

Byrne PJ, Richardson PJ, Chang J, Kusmartseva AF, Allan DR, Jones AC, Kamenev KV, Tasker PA, Parsons S.

Chemistry. 2012 Jun 18;18(25):7738-48. doi: 10.1002/chem.201200213. Epub 2012 May 21.

PMID:
22615125
9.

Phase II trial to evaluate gemcitabine and etoposide for locally advanced or metastatic pancreatic cancer.

Melnik MK, Webb CP, Richardson PJ, Luttenton CR, Campbell AD, Monroe TJ, O'Rourke TJ, Yost KJ, Szczepanek CM, Bassett MR, Truszkowski KJ, Stein P, Van Brocklin MW, Davis AT, Bedolla G, Vande Woude GF, Koo HM.

Mol Cancer Ther. 2010 Aug;9(8):2423-9. doi: 10.1158/1535-7163.MCT-09-0854. Epub 2010 Aug 3.

10.

Natural analogues of degraded ecosystems enhance conservation and reconstruction in extreme environments.

Richardson PJ, Lundholm JT, Larson DW.

Ecol Appl. 2010 Apr;20(3):728-40.

PMID:
20437959
11.

Leptin-mediated inhibition of the insulin-stimulated increase in fatty acid uptake in differentiated 3T3-L1 adipocytes.

Ho M, Foxall S, Higginbottom M, Donofrio DM, Liao J, Richardson PJ, Maneuf YP.

Metabolism. 2006 Jan;55(1):8-12.

PMID:
16324913
12.
13.

Making sense of asthma.

Richardson PJ.

Expert Opin Investig Drugs. 1997 Sep;6(9):1143-7.

PMID:
15991888
14.

Adenosine A1 and A2A receptors are co-expressed in pyramidal neurons and co-localized in glutamatergic nerve terminals of the rat hippocampus.

Rebola N, Rodrigues RJ, Lopes LV, Richardson PJ, Oliveira CR, Cunha RA.

Neuroscience. 2005;133(1):79-83.

PMID:
15893632
15.

Progress in pursuit of therapeutic A2A antagonists: the adenosine A2A receptor selective antagonist KW6002: research and development toward a novel nondopaminergic therapy for Parkinson's disease.

Kase H, Aoyama S, Ichimura M, Ikeda K, Ishii A, Kanda T, Koga K, Koike N, Kurokawa M, Kuwana Y, Mori A, Nakamura J, Nonaka H, Ochi M, Saki M, Shimada J, Shindou T, Shiozaki S, Suzuki F, Takeda M, Yanagawa K, Richardson PJ, Jenner P, Bedard P, Borrelli E, Hauser RA, Chase TN; KW-6002 US-001 Study Group.

Neurology. 2003 Dec 9;61(11 Suppl 6):S97-100. Review.

PMID:
14663020
16.

Detection of enterovirus capsid protein VP1 in myocardium from cases of myocarditis or dilated cardiomyopathy by immunohistochemistry: further evidence of enterovirus persistence in myocytes.

Zhang H, Li Y, McClean DR, Richardson PJ, Florio R, Sheppard M, Morrison K, Latif N, Dunn MJ, Archard LC.

Med Microbiol Immunol. 2004 May;193(2-3):109-14. Epub 2003 Nov 22.

PMID:
14634804
17.

Adenosine modulates the striatal GABAergic inputs to the globus pallidus via adenosine A2A receptors in rats.

Shindou T, Richardson PJ, Mori A, Kase H, Ichimura M.

Neurosci Lett. 2003 Dec 11;352(3):167-70.

PMID:
14625011
18.

Adenosine A3 receptors are located in neurons of the rat hippocampus.

Lopes LV, Rebola N, Pinheiro PC, Richardson PJ, Oliveira CR, Cunha RA.

Neuroreport. 2003 Aug 26;14(12):1645-8.

PMID:
14502093
19.

Orexins induce increased excitability and synchronisation of rat sympathetic preganglionic neurones.

van den Top M, Nolan MF, Lee K, Richardson PJ, Buijs RM, Davies CH, Spanswick D.

J Physiol. 2003 Jun 15;549(Pt 3):809-21. Epub 2003 Apr 17.

20.

Single cell expression analysis--pharmacogenomic potential.

Dixon AK, Lee K, Richardson PJ, Bell MI, Skynner MJ.

Pharmacogenomics. 2002 Nov;3(6):809-22. Review.

PMID:
12437482
22.

Presynaptic adenosine A2A receptors enhance GABAergic synaptic transmission via a cyclic AMP dependent mechanism in the rat globus pallidus.

Shindou T, Nonaka H, Richardson PJ, Mori A, Kase H, Ichimura M.

Br J Pharmacol. 2002 May;136(2):296-302.

23.

Acute dosage with dexrazoxane, but not doxorubicin, is associated with increased rates of hepatic protein synthesis in vivo.

Zima T, Tesar V, Sherwood R, Sood A, Au LC, Richardson PJ, Preedy VR.

Toxicol Pathol. 2001 Nov-Dec;29(6):591-9.

PMID:
11794374
24.

Effects of nitric oxide synthase inhibition on Basal function and the force-frequency relationship in the normal and failing human heart in vivo.

Cotton JM, Kearney MT, MacCarthy PA, Grocott-Mason RM, McClean DR, Heymes C, Richardson PJ, Shah AM.

Circulation. 2001 Nov 6;104(19):2318-23.

25.

Cardioprotective effect of propranolol from alcohol-induced heart muscle damage as assessed by plasma cardiac troponin-t.

Patel VB, Ajmal R, Sherwood RA, Sullivan A, Richardson PJ, Preedy VR.

Alcohol Clin Exp Res. 2001 Jun;25(6):882-9.

PMID:
11410725
26.

Diarrhea reduces the rates of cardiac protein synthesis in myofibrillar protein fractions in rats in vivo.

Hunter RJ, Patel VB, Miell JP, Wong HJ, Marway JS, Richardson PJ, Preedy VR.

J Nutr. 2001 May;131(5):1513-9.

PMID:
11340109
27.

The adenosine A(2A) receptor of the basal ganglia.

Richardson PJ.

J Physiol. 2001 Apr 15;532(Pt 2):284. No abstract available.

28.

Acute doxorubicin (adriamycin) dosage does not reduce cardiac protein synthesis in vivo, but decreases diaminopeptidase I and proline endopeptidase activities.

Zima T, Tesar V, Mantle D, Koll M, Patel V, Richardson PJ, Preedy VR.

Exp Mol Pathol. 2001 Apr;70(2):154-61.

PMID:
11263958
29.

Effects of Doxorubicin (Adriamycin) and [(+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)]propane (ICRF-187) on skeletal muscle protease activities.

Zima T, Tesar V, Richardson PJ, Mantle D, Preedy VR.

Toxicol Appl Pharmacol. 2001 Mar 15;171(3):135-40.

PMID:
11243912
30.

Tissue distribution and functional expression of the human voltage-gated sodium channel beta3 subunit.

Stevens EB, Cox PJ, Shah BS, Dixon AK, Richardson PJ, Pinnock RD, Lee K.

Pflugers Arch. 2001 Jan;441(4):481-8.

PMID:
11212211
31.
32.

Viral myocarditis and dilated cardiomyopathy: mechanisms, manifestations, and management.

Kearney MT, Cotton JM, Richardson PJ, Shah AM.

Postgrad Med J. 2001 Jan;77(903):4-10. Review.

33.
34.
35.

Poor regression of myocardial hypertrophy following concomitant chronic alcohol ingestion and angiotensin converting enzyme (ACE) inhibition.

Patel VB, Sandhu G, Dunn MJ, Mantle D, Rodrigues LM, Griffiths JR, Wassif W, Richardson PJ, Preedy VR.

Life Sci. 2000 Aug 11;67(12):1409-21.

PMID:
10983838
36.

Inability of propranolol to prevent alcohol-induced reductions in cardiac protein synthesis in vivo.

Patel VB, Richardson PJ, Preedy VR.

Clin Chim Acta. 2000 Oct;300(1-2):1-12.

PMID:
10958858
37.

A comparative investigation into the effect of chronic alcohol feeding on the myocardium of normotensive and hypertensive rats: an electrophoretic and biochemical study.

Patel VB, Sandhu G, Corbett JM, Dunn MJ, Rodrigues LM, Griffiths JR, Wassif W, Sherwood RA, Richardson PJ, Preedy VR.

Electrophoresis. 2000 Jul;21(12):2454-62.

PMID:
10939459
38.

Effects of lisinopril and amlodipine on antioxidant status in experimental hypertension.

Mantle D, Patel VB, Why HJ, Ahmed S, Rahman I, MacNee W, Wassif WS, Richardson PJ, Preedy VR.

Clin Chim Acta. 2000 Sep;299(1-2):1-10.

PMID:
10900288
39.

Adenosine receptor expression and function in rat striatal cholinergic interneurons.

Preston Z, Lee K, Widdowson L, Freeman TC, Dixon AK, Richardson PJ.

Br J Pharmacol. 2000 Jun;130(4):886-90.

40.
41.
42.
43.

beta 3: an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics.

Morgan K, Stevens EB, Shah B, Cox PJ, Dixon AK, Lee K, Pinnock RD, Hughes J, Richardson PJ, Mizuguchi K, Jackson AP.

Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2308-13.

44.

Gene-expression analysis at the single-cell level.

Dixon AK, Richardson PJ, Pinnock RD, Lee K.

Trends Pharmacol Sci. 2000 Feb;21(2):65-70. Review.

PMID:
10664611
45.

Tachykinins increase [3H]acetylcholine release in mouse striatum through multiple receptor subtypes.

Preston Z, Lee K, Widdowson L, Richardson PJ, Pinnock RD.

Neuroscience. 2000;95(2):367-76.

PMID:
10658616
46.

Correlating physiology with gene expression in striatal cholinergic neurones.

Richardson PJ, Dixon AK, Lee K, Bell MI, Cox PJ, Williams R, Pinnock RD, Freeman TC.

J Neurochem. 2000 Feb;74(2):839-46.

47.

Analysis of gene expression in single cells.

Freeman TC, Lee K, Richardson PJ.

Curr Opin Biotechnol. 1999 Dec;10(6):579-82. Review.

PMID:
10600693
48.

Oxidants, antioxidants and alcohol: implications for skeletal and cardiac muscle.

Preedy VR, Patel VB, Reilly ME, Richardson PJ, Falkous G, Mantle D.

Front Biosci. 1999 Aug 1;4:e58-66. Review.

PMID:
10430553
49.

Protein metabolism in alcoholism: effects on specific tissues and the whole body.

Preedy VR, Reilly ME, Patel VB, Richardson PJ, Peters TJ.

Nutrition. 1999 Jul-Aug;15(7-8):604-8. Review.

PMID:
10422097
50.

Bombesin-like peptides depolarize rat hippocampal interneurones through interaction with subtype 2 bombesin receptors.

Lee K, Dixon AK, Gonzalez I, Stevens EB, McNulty S, Oles R, Richardson PJ, Pinnock RD, Singh L.

J Physiol. 1999 Aug 1;518 ( Pt 3):791-802.

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