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Items: 1 to 50 of 217

1.

Caloric restriction lowers endocannabinoid tonus and improves cardiac function in type 2 diabetes.

van Eyk HJ, van Schinkel LD, Kantae V, Dronkers CEA, Westenberg JJM, de Roos A, Lamb HJ, Jukema JW, Harms AC, Hankemeier T, van der Stelt M, Jazet IM, Rensen PCN, Smit JWA.

Nutr Diabetes. 2018 Jan 17;8(1):6. doi: 10.1038/s41387-017-0016-7.

PMID:
29343706
2.

The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat.

Schilperoort M, van Dam AD, Hoeke G, Shabalina IG, Okolo A, Hanyaloglu AC, Dib LH, Mol IM, Caengprasath N, Chan YW, Damak S, Miller AR, Coskun T, Shimpukade B, Ulven T, Kooijman S, Rensen PC, Christian M.

EMBO Mol Med. 2018 Jan 17. pii: e8047. doi: 10.15252/emmm.201708047. [Epub ahead of print]

3.

Postprandial metabolite profiles associated with type 2 diabetes clearly stratify individuals with impaired fasting glucose.

Li-Gao R, de Mutsert R, Rensen PCN, van Klinken JB, Prehn C, Adamski J, van Hylckama Vlieg A, den Heijer M, le Cessie S, Rosendaal FR, Willems van Dijk K, Mook-Kanamori DO.

Metabolomics. 2018;14(1):13. doi: 10.1007/s11306-017-1307-7. Epub 2017 Dec 12.

4.

Chronic infusion of taurolithocholate into the brain increases fat oxidation in mice.

Eggink HM, Tambyrajah LL, van den Berg R, Mol IM, van den Heuvel JK, Koehorst M, Groen AK, Boelen A, Kalsbeek A, Romijn JA, Rensen PCN, Kooijman S, Soeters MR.

J Endocrinol. 2018 Feb;236(2):85-97. doi: 10.1530/JOE-17-0503. Epub 2017 Dec 12.

PMID:
29233934
5.

Short-term cooling increases serum angiopoietin-like 4 levels in healthy lean men.

Nahon KJ, Hoeke G, Bakker LEH, Jazet IM, Berbée JFP, Kersten S, Rensen PCN, Boon MR.

J Clin Lipidol. 2018 Jan - Feb;12(1):56-61. doi: 10.1016/j.jacl.2017.10.016. Epub 2017 Nov 1.

PMID:
29191670
6.

Mendelian randomization analysis of cholesteryl ester transfer protein and subclinical atherosclerosis: A population-based study.

Christen T, Trompet S, Noordam R, Blauw LL, Gast KB, Rensen PCN, Willems van Dijk K, Rosendaal FR, de Mutsert R, Jukema JW; NEO study.

J Clin Lipidol. 2018 Jan - Feb;12(1):137-144.e1. doi: 10.1016/j.jacl.2017.10.023. Epub 2017 Nov 2.

PMID:
29174438
7.

A New Personalized Cooling Protocol to Activate Brown Adipose Tissue in Young Adults.

Martinez-Tellez B, Sanchez-Delgado G, Garcia-Rivero Y, Alcantara JMA, Martinez-Avila WD, Muñoz-Hernandez MV, Olza J, Boon MR, Rensen PCN, Llamas-Elvira JM, Ruiz JR.

Front Physiol. 2017 Nov 2;8:863. doi: 10.3389/fphys.2017.00863. eCollection 2017.

8.

Atorvastatin accelerates clearance of lipoprotein remnants generated by activated brown fat to further reduce hypercholesterolemia and atherosclerosis.

Hoeke G, Wang Y, van Dam AD, Mol IM, Gart E, Klop HG, van den Berg SM, Pieterman EH, Princen HMG, Groen AK, Rensen PCN, Berbée JFP, Boon MR.

Atherosclerosis. 2017 Dec;267:116-126. doi: 10.1016/j.atherosclerosis.2017.10.030. Epub 2017 Oct 26.

PMID:
29121499
9.

Butyrate reduces appetite and activates brown adipose tissue via the gut-brain neural circuit.

Li Z, Yi CX, Katiraei S, Kooijman S, Zhou E, Chung CK, Gao Y, van den Heuvel JK, Meijer OC, Berbée JFP, Heijink M, Giera M, Willems van Dijk K, Groen AK, Rensen PCN, Wang Y.

Gut. 2017 Nov 3. pii: gutjnl-2017-314050. doi: 10.1136/gutjnl-2017-314050. [Epub ahead of print]

PMID:
29101261
10.

Male apoE*3-Leiden.CETP mice on high-fat high-cholesterol diet exhibit a biphasic dyslipidemic response, mimicking the changes in plasma lipids observed through life in men.

Paalvast Y, Gerding A, Wang Y, Bloks VW, van Dijk TH, Havinga R, Willems van Dijk K, Rensen PCN, Bakker BM, Kuivenhoven JA, Groen AK.

Physiol Rep. 2017 Oct;5(19). pii: e13376. doi: 10.14814/phy2.13376. Epub 2017 Oct 16.

11.

Lower critical temperature and cold-induced thermogenesis of lean and overweight humans are inversely related to body mass and basal metabolic rate.

Nahon KJ, Boon MR, Doornink F, Jazet IM, Rensen PCN, Abreu-Vieira G.

J Therm Biol. 2017 Oct;69:238-248. doi: 10.1016/j.jtherbio.2017.08.006. Epub 2017 Aug 12.

PMID:
29037389
12.

Metabolic imaging of fatty kidney in diabesity: validation and dietary intervention.

Jonker JT, de Heer P, Engelse MA, van Rossenberg EH, Klessens CQF, Baelde HJ, Bajema IM, Koopmans SJ, Coelho PG, Streefland TCM, Webb AG, Dekkers IA, Rabelink TJ, Rensen PCN, Lamb HJ, de Vries APJ.

Nephrol Dial Transplant. 2018 Feb 1;33(2):224-230. doi: 10.1093/ndt/gfx243.

PMID:
28992141
13.

Selective Glucocorticoid Receptor Antagonist CORT125281 Activates Brown Adipose Tissue and Alters Lipid Distribution in Male Mice.

Kroon J, Koorneef LL, van den Heuvel JK, Verzijl CRC, van de Velde NM, Mol IM, Sips HCM, Hunt H, Rensen PCN, Meijer OC.

Endocrinology. 2018 Jan 1;159(1):535-546. doi: 10.1210/en.2017-00512.

PMID:
28938459
14.

Acute and chronic effects of treatment with mesenchymal stromal cells on LPS-induced pulmonary inflammation, emphysema and atherosclerosis development.

Khedoe PPSJ, de Kleijn S, van Oeveren-Rietdijk AM, Plomp JJ, de Boer HC, van Pel M, Rensen PCN, Berbée JFP, Hiemstra PS.

PLoS One. 2017 Sep 14;12(9):e0183741. doi: 10.1371/journal.pone.0183741. eCollection 2017.

15.

South Asian men have lower expression of IFN signalling genes in white adipose tissue and skeletal muscle compared with white men.

van Dam AD, Hanssen MJW, van Eenige R, Quinten E, Sips HC, Hülsman CJM, Jazet IM, van Marken Lichtenbelt WD, Ottenhoff THM, Haks MC, Rensen PCN, Boon MR.

Diabetologia. 2017 Dec;60(12):2525-2528. doi: 10.1007/s00125-017-4427-8. Epub 2017 Sep 8. No abstract available.

PMID:
28887664
16.

Differences between the most used equations in BAT-human studies to estimate parameters of skin temperature in young lean men.

Martinez-Tellez B, Sanchez-Delgado G, Acosta FM, Alcantara JMA, Boon MR, Rensen PCN, Ruiz JR.

Sci Rep. 2017 Sep 5;7(1):10530. doi: 10.1038/s41598-017-10444-5.

17.

IgG is elevated in obese white adipose tissue but does not induce glucose intolerance via Fcγ-receptor or complement.

van Dam AD, van Beek L, Pronk ACM, van den Berg SM, Van den Bossche J, de Winther MPJ, Koning F, van Kooten C, Rensen PCN, Boon MR, Verbeek JS, van Dijk KW, van Harmelen V.

Int J Obes (Lond). 2018 Feb;42(2):260-269. doi: 10.1038/ijo.2017.209. Epub 2017 Aug 30.

PMID:
28852207
18.

The Effects of Selective Hematopoietic Expression of Human IL-37 on Systemic Inflammation and Atherosclerosis in LDLr-Deficient Mice.

Hoeke G, Khedoe PPSJ, van Diepen JA, Pike-Overzet K, van de Ven B, Vazirpanah N, Mol I, Hiemstra PS, Staal FJT, Stienstra R, Netea MG, Dinarello CA, Rensen PCN, Berbée JFP.

Int J Mol Sci. 2017 Aug 9;18(8). pii: E1672. doi: 10.3390/ijms18081672.

19.

Endocannabinoid tone is higher in healthy lean South Asian than white Caucasian men.

Kantae V, Nahon KJ, Straat ME, Bakker LEH, Harms AC, van der Stelt M, Hankemeier T, Jazet IM, Boon MR, Rensen PCN.

Sci Rep. 2017 Aug 8;7(1):7558. doi: 10.1038/s41598-017-07980-5.

20.

Helminth antigens counteract a rapid high-fat diet-induced decrease in adipose tissue eosinophils.

van den Berg SM, van Dam AD, Kusters PJH, Beckers L, den Toom M, van der Velden S, Van den Bossche J, van Die I, Boon MR, Rensen PCN, Lutgens E, de Winther MPJ.

J Mol Endocrinol. 2017 Oct;59(3):245-255. doi: 10.1530/JME-17-0112. Epub 2017 Jul 10.

PMID:
28694301
21.

Deuterium-reinforced polyunsaturated fatty acids protect against atherosclerosis by lowering lipid peroxidation and hypercholesterolemia.

Berbée JFP, Mol IM, Milne GL, Pollock E, Hoeke G, Lütjohann D, Monaco C, Rensen PCN, van der Ploeg LHT, Shchepinov MS.

Atherosclerosis. 2017 Sep;264:100-107. doi: 10.1016/j.atherosclerosis.2017.06.916. Epub 2017 Jun 21.

PMID:
28655430
22.

Genetic variation in the obesity gene FTO is not associated with decreased fat oxidation: the NEO study.

Blauw LL, Noordam R, Trompet S, Berbée JFP, Rosendaal FR, van Heemst D, van Dijk KW, Mook-Kanamori DO, de Mutsert R, Rensen PCN.

Int J Obes (Lond). 2017 Oct;41(10):1594-1600. doi: 10.1038/ijo.2017.146. Epub 2017 Jun 19.

PMID:
28626215
23.

Short-term cooling increases serum triglycerides and small high-density lipoprotein levels in humans.

Hoeke G, Nahon KJ, Bakker LEH, Norkauer SSC, Dinnes DLM, Kockx M, Lichtenstein L, Drettwan D, Reifel-Miller A, Coskun T, Pagel P, Romijn FPHTM, Cobbaert CM, Jazet IM, Martinez LO, Kritharides L, Berbée JFP, Boon MR, Rensen PCN.

J Clin Lipidol. 2017 Jul - Aug;11(4):920-928.e2. doi: 10.1016/j.jacl.2017.04.117. Epub 2017 May 3.

PMID:
28625343
24.

Association of fasting triglyceride concentration and postprandial triglyceride response with the carotid intima-media thickness in the middle aged: The Netherlands Epidemiology of Obesity study.

Christen T, de Mutsert R, Gast KB, Rensen PCN, de Koning E, Rosendaal FR, Trompet S, Jukema JW.

J Clin Lipidol. 2017 Mar - Apr;11(2):377-385.e1. doi: 10.1016/j.jacl.2016.12.016. Epub 2017 Jan 23.

PMID:
28502494
25.

BMT decreases HFD-induced weight gain associated with decreased preadipocyte number and insulin secretion.

Katiraei S, Hoving LR, van Beek L, Mohamedhoesein S, Carlotti F, van Diepen JA, Rensen PCN, Netea MG, Willems van Dijk K, Berbée JFP, van Harmelen V.

PLoS One. 2017 Apr 26;12(4):e0175524. doi: 10.1371/journal.pone.0175524. eCollection 2017.

26.

Familial longevity is characterized by high circadian rhythmicity of serum cholesterol in healthy elderly individuals.

van den Berg R, Noordam R, Kooijman S, Jansen SWM, Akintola AA, Slagboom PE, Pijl H, Rensen PCN, Biermasz NR, van Heemst D.

Aging Cell. 2017 Apr;16(2):237-243. doi: 10.1111/acel.12547. Epub 2016 Nov 19.

27.

Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport.

Bartelt A, John C, Schaltenberg N, Berbée JFP, Worthmann A, Cherradi ML, Schlein C, Piepenburg J, Boon MR, Rinninger F, Heine M, Toedter K, Niemeier A, Nilsson SK, Fischer M, Wijers SL, van Marken Lichtenbelt W, Scheja L, Rensen PCN, Heeren J.

Nat Commun. 2017 Apr 19;8:15010. doi: 10.1038/ncomms15010.

28.

Diabetes incidence and glucose intolerance prevalence increase with higher outdoor temperature.

Blauw LL, Aziz NA, Tannemaat MR, Blauw CA, de Craen AJ, Pijl H, Rensen PC.

BMJ Open Diabetes Res Care. 2017 Feb 20;5(1):e000317. doi: 10.1136/bmjdrc-2016-000317. eCollection 2017.

29.

Targeting white, brown and perivascular adipose tissue in atherosclerosis development.

van Dam AD, Boon MR, Berbée JFP, Rensen PCN, van Harmelen V.

Eur J Pharmacol. 2017 Dec 5;816:82-92. doi: 10.1016/j.ejphar.2017.03.051. Epub 2017 Mar 24.

30.

LysoPC-acyl C16:0 is associated with brown adipose tissue activity in men.

Boon MR, Bakker LEH, Prehn C, Adamski J, Vosselman MJ, Jazet IM, Arias-Bouda LMP, van Lichtenbelt WDM, van Dijk KW, Rensen PCN, Mook-Kanamori DO.

Metabolomics. 2017;13(5):48. doi: 10.1007/s11306-017-1185-z. Epub 2017 Mar 3.

31.

Activation and quantification of human brown adipose tissue: Methodological considerations for between studies comparisons: Comment on: Hot heads & cool bodies: The conundrums of human BAT activity research.

Martinez-Tellez B, Sanchez-Delgado G, Boon MR, Rensen PCN, Ruiz JR.

Eur J Intern Med. 2017 May;40:e19-e21. doi: 10.1016/j.ejim.2017.02.006. Epub 2017 Feb 16. No abstract available.

PMID:
28215976
32.

Human Neutrophil Peptide 1 Limits Hypercholesterolemia-induced Atherosclerosis by Increasing Hepatic LDL Clearance.

Paulin N, Döring Y, Kooijman S, Blanchet X, Viola JR, de Jong R, Mandl M, Hendrikse J, Schiener M, von Hundelshausen P, Vogt A, Weber C, Bdeir K, Hofmann SM, Rensen PCN, Drechsler M, Soehnlein O.

EBioMedicine. 2017 Feb;16:204-211. doi: 10.1016/j.ebiom.2017.01.006. Epub 2017 Jan 7.

33.

Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding.

Deng H, Kooijman S, van den Nieuwendijk AM, Ogasawara D, van der Wel T, van Dalen F, Baggelaar MP, Janssen FJ, van den Berg RJ, den Dulk H, Cravatt BF, Overkleeft HS, Rensen PC, van der Stelt M.

J Med Chem. 2017 Jan 12;60(1):428-440. doi: 10.1021/acs.jmedchem.6b01482. Epub 2016 Dec 19.

PMID:
27992221
34.

Apolipoprotein C-I plays a role in the pathogenesis of glomerulosclerosis.

Bus P, Pierneef L, Bor R, Wolterbeek R, van Es LA, Rensen PC, de Heer E, Havekes LM, Bruijn JA, Berbée JF, Baelde HJ.

J Pathol. 2017 Apr;241(5):589-599. doi: 10.1002/path.4859. Epub 2017 Feb 2.

PMID:
27976371
35.

Immune Modulation of Brown(ing) Adipose Tissue in Obesity.

van den Berg SM, van Dam AD, Rensen PC, de Winther MP, Lutgens E.

Endocr Rev. 2017 Feb 1;38(1):46-68. doi: 10.1210/er.2016-1066. Review.

PMID:
27849358
36.

Abca1 deficiency protects the heart against myocardial infarction-induced injury.

Louwe MC, Lammers B, Frias MA, Foks AC, de Leeuw LR, Hildebrand RB, Kuiper J, Smit JWA, Van Berkel TJC, James RW, Geerling JJ, Rensen PCN, Van Eck M.

Atherosclerosis. 2016 Aug;251:159-163. doi: 10.1016/j.atherosclerosis.2016.06.023. Epub 2016 Jun 11.

37.

BCG lowers plasma cholesterol levels and delays atherosclerotic lesion progression in mice.

van Dam AD, Bekkering S, Crasborn M, van Beek L, van den Berg SM, Vrieling F, Joosten SA, van Harmelen V, de Winther MPJ, Lütjohann D, Lutgens E, Boon MR, Riksen NP, Rensen PCN, Berbée JFP.

Atherosclerosis. 2016 Aug;251:6-14. doi: 10.1016/j.atherosclerosis.2016.05.031. Epub 2016 May 19.

38.

Low-Density Lipoprotein Receptor-Dependent and Low-Density Lipoprotein Receptor-Independent Mechanisms of Cyclosporin A-Induced Dyslipidemia.

Kockx M, Glaros E, Leung B, Ng TW, Berbée JF, Deswaerte V, Nawara D, Quinn C, Rye KA, Jessup W, Rensen PC, Meikle PJ, Kritharides L.

Arterioscler Thromb Vasc Biol. 2016 Jul;36(7):1338-49. doi: 10.1161/ATVBAHA.115.307030. Epub 2016 May 5.

39.

Deficiency of the oxygen sensor prolyl hydroxylase 1 attenuates hypercholesterolaemia, atherosclerosis, and hyperglycaemia.

Marsch E, Demandt JA, Theelen TL, Tullemans BM, Wouters K, Boon MR, van Dijk TH, Gijbels MJ, Dubois LJ, Meex SJ, Mazzone M, Hung G, Fisher EA, Biessen EA, Daemen MJ, Rensen PC, Carmeliet P, Groen AK, Sluimer JC.

Eur Heart J. 2016 Oct 14;37(39):2993-2997. Epub 2016 Apr 28.

40.

HDL functionality in South Asians as compared to white Caucasians.

Bakker LE, Boon MR, Annema W, Dikkers A, van Eyk HJ, Verhoeven A, Mayboroda OA, Jukema JW, Havekes LM, Meinders AE, Willems van Dijk K, Jazet IM, Tietge UJ, Rensen PC.

Nutr Metab Cardiovasc Dis. 2016 Aug;26(8):697-705. doi: 10.1016/j.numecd.2016.02.010. Epub 2016 Feb 19.

PMID:
27052926
41.

Relevance of lipid metabolism for brown fat visualization and quantification.

Schilperoort M, Hoeke G, Kooijman S, Rensen PC.

Curr Opin Lipidol. 2016 Jun;27(3):242-8. doi: 10.1097/MOL.0000000000000296. Review.

PMID:
27023630
42.

Murine models of cardiovascular comorbidity in chronic obstructive pulmonary disease.

Khedoe PP, Rensen PC, Berbée JF, Hiemstra PS.

Am J Physiol Lung Cell Mol Physiol. 2016 Jun 1;310(11):L1011-27. doi: 10.1152/ajplung.00013.2016. Epub 2016 Mar 18. Review.

43.

Identification of a selective glucocorticoid receptor modulator that prevents both diet-induced obesity and inflammation.

van den Heuvel JK, Boon MR, van Hengel I, Peschier-van der Put E, van Beek L, van Harmelen V, van Dijk KW, Pereira AM, Hunt H, Belanoff JK, Rensen PC, Meijer OC.

Br J Pharmacol. 2016 Jun;173(11):1793-804. doi: 10.1111/bph.13477. Epub 2016 Apr 24.

44.

Role of Brown Fat in Lipoprotein Metabolism and Atherosclerosis.

Hoeke G, Kooijman S, Boon MR, Rensen PC, Berbée JF.

Circ Res. 2016 Jan 8;118(1):173-82. doi: 10.1161/CIRCRESAHA.115.306647. Review.

45.

Serum CETP concentration is not associated with measures of body fat: The NEO study.

Blauw LL, de Mutsert R, Lamb HJ, de Roos A, Rosendaal FR, Jukema JW, Wang Y, van Dijk KW, Rensen PC.

Atherosclerosis. 2016 Mar;246:267-73. doi: 10.1016/j.atherosclerosis.2016.01.031. Epub 2016 Jan 19.

46.

USF1 deficiency activates brown adipose tissue and improves cardiometabolic health.

Laurila PP, Soronen J, Kooijman S, Forsström S, Boon MR, Surakka I, Kaiharju E, Coomans CP, Van Den Berg SA, Autio A, Sarin AP, Kettunen J, Tikkanen E, Manninen T, Metso J, Silvennoinen R, Merikanto K, Ruuth M, Perttilä J, Mäkelä A, Isomi A, Tuomainen AM, Tikka A, Ramadan UA, Seppälä I, Lehtimäki T, Eriksson J, Havulinna A, Jula A, Karhunen PJ, Salomaa V, Perola M, Ehnholm C, Lee-Rueckert M, Van Eck M, Roivainen A, Taskinen MR, Peltonen L, Mervaala E, Jalanko A, Hohtola E, Olkkonen VM, Ripatti S, Kovanen PT, Rensen PC, Suomalainen A, Jauhiainen M.

Sci Transl Med. 2016 Jan 27;8(323):323ra13. doi: 10.1126/scitranslmed.aad0015.

PMID:
26819196
47.

Reply to "Letter to the editor: Parasympathetic innervation of the rodent spleen?".

Kooijman S, de Jonge WJ, Rensen PC.

Am J Physiol Heart Circ Physiol. 2015 Dec 15;309(12):H2159. doi: 10.1152/ajpheart.00805.2015. No abstract available.

48.

FcRγ-chain deficiency reduces the development of diet-induced obesity.

van Beek L, Vroegrijk IO, Katiraei S, Heemskerk MM, van Dam AD, Kooijman S, Rensen PC, Koning F, Verbeek JS, Willems van Dijk K, van Harmelen V.

Obesity (Silver Spring). 2015 Dec;23(12):2435-44. doi: 10.1002/oby.21309. Epub 2015 Nov 2.

49.

Neuronal Control of Brown Fat Activity.

Kooijman S, van den Heuvel JK, Rensen PC.

Trends Endocrinol Metab. 2015 Nov;26(11):657-68. doi: 10.1016/j.tem.2015.09.008. Epub 2015 Oct 17. Review.

PMID:
26482876
50.

ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure.

Dijk W, Heine M, Vergnes L, Boon MR, Schaart G, Hesselink MK, Reue K, van Marken Lichtenbelt WD, Olivecrona G, Rensen PC, Heeren J, Kersten S.

Elife. 2015 Oct 17;4. pii: e08428. doi: 10.7554/eLife.08428.

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