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Items: 1 to 50 of 135

1.

Hedgehog Pathway Drives Fusion-Negative Rhabdomyosarcoma Initiated From Non-myogenic Endothelial Progenitors.

Drummond CJ, Hanna JA, Garcia MR, Devine DJ, Heyrana AJ, Finkelstein D, Rehg JE, Hatley ME.

Cancer Cell. 2018 Jan 8;33(1):108-124.e5. doi: 10.1016/j.ccell.2017.12.001.

PMID:
29316425
2.

Biallelic Dicer1 Loss Mediated by aP2-Cre Drives Angiosarcoma.

Hanna JA, Drummond CJ, Garcia MR, Go JC, Finkelstein D, Rehg JE, Hatley ME.

Cancer Res. 2017 Nov 15;77(22):6109-6118. doi: 10.1158/0008-5472.CAN-17-1262. Epub 2017 Sep 15.

PMID:
28916654
3.

ATM-deficiency increases genomic instability and metastatic potential in a mouse model of pancreatic cancer.

Drosos Y, Escobar D, Chiang MY, Roys K, Valentine V, Valentine MB, Rehg JE, Sahai V, Begley LA, Ye J, Paul L, McKinnon PJ, Sosa-Pineda B.

Sci Rep. 2017 Sep 11;7(1):11144. doi: 10.1038/s41598-017-11661-8.

4.

Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells.

Kawauchi D, Ogg RJ, Liu L, Shih DJH, Finkelstein D, Murphy BL, Rehg JE, Korshunov A, Calabrese C, Zindy F, Phoenix T, Kawaguchi Y, Gronych J, Gilbertson RJ, Lichter P, Gajjar A, Kool M, Northcott PA, Pfister SM, Roussel MF.

Oncogene. 2017 Sep 14;36(37):5231-5242. doi: 10.1038/onc.2017.110. Epub 2017 May 15.

5.

Globule Leukocytes and Other Mast Cells in the Mouse Intestine.

Vogel P, Janke L, Gravano DM, Lu M, Sawant DV, Bush D, Shuyu E, Vignali DAA, Pillai A, Rehg JE.

Vet Pathol. 2018 Jan;55(1):76-97. doi: 10.1177/0300985817705174. Epub 2017 May 11.

PMID:
28494703
6.

MYCN induces neuroblastoma in primary neural crest cells.

Olsen RR, Otero JH, García-López J, Wallace K, Finkelstein D, Rehg JE, Yin Z, Wang YD, Freeman KW.

Oncogene. 2017 Aug 31;36(35):5075-5082. doi: 10.1038/onc.2017.128. Epub 2017 May 1.

7.

Excess coenzyme A reduces skeletal muscle performance and strength in mice overexpressing human PANK2.

Corbin DR, Rehg JE, Shepherd DL, Stoilov P, Percifield RJ, Horner L, Frase S, Zhang YM, Rock CO, Hollander JM, Jackowski S, Leonardi R.

Mol Genet Metab. 2017 Apr;120(4):350-362. doi: 10.1016/j.ymgme.2017.02.001. Epub 2017 Feb 3.

PMID:
28189602
8.

Transgenic mouse model of IgM+ lymphoproliferative disease mimicking Waldenström macroglobulinemia.

Tompkins VS, Sompallae R, Rosean TR, Walsh S, Acevedo M, Kovalchuk AL, Han SS, Jing X, Holman C, Rehg JE, Herms S, Sunderland JS, Morse HC, Janz S.

Blood Cancer J. 2016 Nov 4;6(11):e488. doi: 10.1038/bcj.2016.95.

9.

Highly Pathogenic Reassortant Avian Influenza A(H5N1) Virus Clade 2.3.2.1a in Poultry, Bhutan.

Marinova-Petkova A, Franks J, Tenzin S, Dahal N, Dukpa K, Dorjee J, Feeroz MM, Rehg JE, Barman S, Krauss S, McKenzie P, Webby RJ, Webster RG.

Emerg Infect Dis. 2016 Dec;22(12):2137-2141. doi: 10.3201/eid2212.160611. Epub 2016 Dec 15.

10.

Recommendations from the INHAND Apoptosis/Necrosis Working Group.

Elmore SA, Dixon D, Hailey JR, Harada T, Herbert RA, Maronpot RR, Nolte T, Rehg JE, Rittinghausen S, Rosol TJ, Satoh H, Vidal JD, Willard-Mack CL, Creasy DM.

Toxicol Pathol. 2016 Feb;44(2):173-88. doi: 10.1177/0192623315625859. Epub 2016 Feb 14.

11.

Molecular requirements for a pandemic influenza virus: An acid-stable hemagglutinin protein.

Russier M, Yang G, Rehg JE, Wong SS, Mostafa HH, Fabrizio TP, Barman S, Krauss S, Webster RG, Webby RJ, Russell CJ.

Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):1636-41. doi: 10.1073/pnas.1524384113. Epub 2016 Jan 25.

12.

The Interaction of Myc with Miz1 Defines Medulloblastoma Subgroup Identity.

Vo BT, Wolf E, Kawauchi D, Gebhardt A, Rehg JE, Finkelstein D, Walz S, Murphy BL, Youn YH, Han YG, Eilers M, Roussel MF.

Cancer Cell. 2016 Jan 11;29(1):5-16. doi: 10.1016/j.ccell.2015.12.003.

13.

IL-21-driven neoplasms in SJL mice mimic some key features of human angioimmunoblastic T-cell lymphoma.

Jain S, Chen J, Nicolae A, Wang H, Shin DM, Adkins EB, Sproule TJ, Leeth CM, Sakai T, Kovalchuk AL, Raffeld M, Ward JM, Rehg JE, Waldmann TA, Jaffe ES, Roopenian DC, Morse HC 3rd.

Am J Pathol. 2015 Nov;185(11):3102-14. doi: 10.1016/j.ajpath.2015.07.021. Epub 2015 Sep 9.

14.

Immunophenotype of Spontaneous Hematolymphoid Tumors Occurring in Young and Aging Female CD-1 Mice. [Corrected].

Rehg JE, Rahija R, Bush D, Bradley A, Ward JM.

Toxicol Pathol. 2015 Oct;43(7):1025-34. doi: 10.1177/0192623315587922. Epub 2015 Jul 28. Erratum in: Toxicol Pathol. 2015 Dec;43(8):1172.

15.

Induction of Neuron-Specific Degradation of Coenzyme A Models Pantothenate Kinase-Associated Neurodegeneration by Reducing Motor Coordination in Mice.

Shumar SA, Fagone P, Alfonso-Pecchio A, Gray JT, Rehg JE, Jackowski S, Leonardi R.

PLoS One. 2015 Jun 8;10(6):e0130013. doi: 10.1371/journal.pone.0130013. eCollection 2015.

16.

LKB1 inhibition of NF-κB in B cells prevents T follicular helper cell differentiation and germinal center formation.

Walsh NC, Waters LR, Fowler JA, Lin M, Cunningham CR, Brooks DG, Rehg JE, Morse HC 3rd, Teitell MA.

EMBO Rep. 2015 Jun;16(6):753-68. doi: 10.15252/embr.201439505. Epub 2015 Apr 26.

17.

Mammalian adaptation of influenza A(H7N9) virus is limited by a narrow genetic bottleneck.

Zaraket H, Baranovich T, Kaplan BS, Carter R, Song MS, Paulson JC, Rehg JE, Bahl J, Crumpton JC, Seiler J, Edmonson M, Wu G, Karlsson E, Fabrizio T, Zhu H, Guan Y, Husain M, Schultz-Cherry S, Krauss S, McBride R, Webster RG, Govorkova EA, Zhang J, Russell CJ, Webby RJ.

Nat Commun. 2015 Apr 8;6:6553. doi: 10.1038/ncomms7553.

18.

Rodent immunohistochemistry: pitfalls and troubleshooting.

Ward JM, Rehg JE.

Vet Pathol. 2014 Jan;51(1):88-101. doi: 10.1177/0300985813503571. Epub 2013 Sep 27. Review.

PMID:
24078006
19.

Fecal influenza in mammals: selection of novel variants.

Koçer ZA, Obenauer J, Zaraket H, Zhang J, Rehg JE, Russell CJ, Webster RG.

J Virol. 2013 Nov;87(21):11476-86. doi: 10.1128/JVI.01544-13. Epub 2013 Aug 21.

20.

Requirement for antiapoptotic MCL-1 in the survival of BCR-ABL B-lineage acute lymphoblastic leukemia.

Koss B, Morrison J, Perciavalle RM, Singh H, Rehg JE, Williams RT, Opferman JT.

Blood. 2013 Aug 29;122(9):1587-98. doi: 10.1182/blood-2012-06-440230. Epub 2013 Jul 23.

21.

Deletion of MCL-1 causes lethal cardiac failure and mitochondrial dysfunction.

Wang X, Bathina M, Lynch J, Koss B, Calabrese C, Frase S, Schuetz JD, Rehg JE, Opferman JT.

Genes Dev. 2013 Jun 15;27(12):1351-64. doi: 10.1101/gad.215855.113.

22.

Th-MYCN mice with caspase-8 deficiency develop advanced neuroblastoma with bone marrow metastasis.

Teitz T, Inoue M, Valentine MB, Zhu K, Rehg JE, Zhao W, Finkelstein D, Wang YD, Johnson MD, Calabrese C, Rubinstein M, Hakem R, Weiss WA, Lahti JM.

Cancer Res. 2013 Jul 1;73(13):4086-97. doi: 10.1158/0008-5472.CAN-12-2681. Epub 2013 Mar 27.

23.

The potential of avian H1N1 influenza A viruses to replicate and cause disease in mammalian models.

Koçer ZA, Krauss S, Stallknecht DE, Rehg JE, Webster RG.

PLoS One. 2012;7(7):e41609. doi: 10.1371/journal.pone.0041609. Epub 2012 Jul 25.

24.

Pathogenicity and transmissibility of North American triple reassortant swine influenza A viruses in ferrets.

Barman S, Krylov PS, Fabrizio TP, Franks J, Turner JC, Seiler P, Wang D, Rehg JE, Erickson GA, Gramer M, Webster RG, Webby RJ.

PLoS Pathog. 2012;8(7):e1002791. doi: 10.1371/journal.ppat.1002791. Epub 2012 Jul 19.

25.

Germline deletion of pantothenate kinases 1 and 2 reveals the key roles for CoA in postnatal metabolism.

Garcia M, Leonardi R, Zhang YM, Rehg JE, Jackowski S.

PLoS One. 2012;7(7):e40871. doi: 10.1371/journal.pone.0040871. Epub 2012 Jul 17.

26.

Both influenza hemagglutinin and polymerase acidic genes are important for delayed pandemic 2009 H1N1 virus clearance in the ferret model.

Ducatez MF, Ilyushina NA, Fabrizio TP, Rehg JE, Bovin NV, Webster RG, Webby RJ.

Virology. 2012 Oct 25;432(2):389-93. doi: 10.1016/j.virol.2012.06.018. Epub 2012 Jul 17.

27.

Cryptogenic organizing pneumonia in Tomm5(-/-) mice.

Vogel P, Read RW, Rehg JE, Hansen GM.

Vet Pathol. 2013 Jan;50(1):65-75. doi: 10.1177/0300985812450723. Epub 2012 Jun 11.

PMID:
22688586
28.

Loss of epigenetic modification driven by the Foxp3 transcription factor leads to regulatory T cell insufficiency.

Bettini ML, Pan F, Bettini M, Finkelstein D, Rehg JE, Floess S, Bell BD, Ziegler SF, Huehn J, Pardoll DM, Vignali DA.

Immunity. 2012 May 25;36(5):717-30. doi: 10.1016/j.immuni.2012.03.020. Epub 2012 May 10.

29.

NIK prevents the development of hypereosinophilic syndrome-like disease in mice independent of IKKα activation.

Häcker H, Chi L, Rehg JE, Redecke V.

J Immunol. 2012 May 1;188(9):4602-10. doi: 10.4049/jimmunol.1200021. Epub 2012 Apr 2.

31.

ATP-dependent mitochondrial porphyrin importer ABCB6 protects against phenylhydrazine toxicity.

Ulrich DL, Lynch J, Wang Y, Fukuda Y, Nachagari D, Du G, Sun D, Fan Y, Tsurkan L, Potter PM, Rehg JE, Schuetz JD.

J Biol Chem. 2012 Apr 13;287(16):12679-90. doi: 10.1074/jbc.M111.336180. Epub 2012 Jan 31.

32.

Differentiation of rodent immune and hematopoietic system reactive lesions from neoplasias.

Ward JM, Rehg JE, Morse HC 3rd.

Toxicol Pathol. 2012 Apr;40(3):425-34. doi: 10.1177/0192623311431467. Epub 2012 Jan 3. Review.

33.

Morphological and immunohistochemical characterization of sarcomatous tumors in wild-type and genetically engineered mice.

Rehg JE, Ward JM.

Vet Pathol. 2012 Jan;49(1):206-17. doi: 10.1177/0300985811429813. Epub 2011 Dec 6.

PMID:
22146848
34.

Genetically defining the mechanism of Puma- and Bim-induced apoptosis.

Garrison SP, Phillips DC, Jeffers JR, Chipuk JE, Parsons MJ, Rehg JE, Opferman JT, Green DR, Zambetti GP.

Cell Death Differ. 2012 Apr;19(4):642-9. doi: 10.1038/cdd.2011.136. Epub 2011 Oct 21.

35.

The plasticity of regulatory T cell function.

Pillai MR, Collison LW, Wang X, Finkelstein D, Rehg JE, Boyd K, Szymczak-Workman AL, Doggett T, Griffith TS, Ferguson TA, Vignali DA.

J Immunol. 2011 Nov 15;187(10):4987-97. doi: 10.4049/jimmunol.1102173. Epub 2011 Oct 17.

36.

A20-binding inhibitor of NF-κB (ABIN1) controls Toll-like receptor-mediated CCAAT/enhancer-binding protein β activation and protects from inflammatory disease.

Zhou J, Wu R, High AA, Slaughter CA, Finkelstein D, Rehg JE, Redecke V, Häcker H.

Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):E998-1006. doi: 10.1073/pnas.1106232108. Epub 2011 Oct 19.

37.

Increased pathogenicity of a reassortant 2009 pandemic H1N1 influenza virus containing an H5N1 hemagglutinin.

Cline TD, Karlsson EA, Freiden P, Seufzer BJ, Rehg JE, Webby RJ, Schultz-Cherry S.

J Virol. 2011 Dec;85(23):12262-70. doi: 10.1128/JVI.05582-11. Epub 2011 Sep 14.

38.

Assessment of the efficacy of the neuraminidase inhibitor oseltamivir against 2009 pandemic H1N1 influenza virus in ferrets.

Govorkova EA, Marathe BM, Prevost A, Rehg JE, Webster RG.

Antiviral Res. 2011 Aug;91(2):81-8. doi: 10.1016/j.antiviral.2011.05.008. Epub 2011 May 27.

39.

Preclinical models for neuroblastoma: establishing a baseline for treatment.

Teitz T, Stanke JJ, Federico S, Bradley CL, Brennan R, Zhang J, Johnson MD, Sedlacik J, Inoue M, Zhang ZM, Frase S, Rehg JE, Hillenbrand CM, Finkelstein D, Calabrese C, Dyer MA, Lahti JM.

PLoS One. 2011 Apr 29;6(4):e19133. doi: 10.1371/journal.pone.0019133.

40.

Activity of the multikinase inhibitor sorafenib in combination with cytarabine in acute myeloid leukemia.

Hu S, Niu H, Inaba H, Orwick S, Rose C, Panetta JC, Yang S, Pounds S, Fan Y, Calabrese C, Rehg JE, Campana D, Rubnitz JE, Baker SD.

J Natl Cancer Inst. 2011 Jun 8;103(11):893-905. doi: 10.1093/jnci/djr107. Epub 2011 Apr 12.

41.

DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair.

Gao Y, Katyal S, Lee Y, Zhao J, Rehg JE, Russell HR, McKinnon PJ.

Nature. 2011 Mar 10;471(7337):240-4. doi: 10.1038/nature09773.

42.

In vivo Treg suppression assays.

Workman CJ, Collison LW, Bettini M, Pillai MR, Rehg JE, Vignali DA.

Methods Mol Biol. 2011;707:119-56. doi: 10.1007/978-1-61737-979-6_9.

43.

Chemotherapeutic agents circumvent emergence of dasatinib-resistant BCR-ABL kinase mutations in a precise mouse model of Philadelphia chromosome-positive acute lymphoblastic leukemia.

Boulos N, Mulder HL, Calabrese CR, Morrison JB, Rehg JE, Relling MV, Sherr CJ, Williams RT.

Blood. 2011 Mar 31;117(13):3585-95. doi: 10.1182/blood-2010-08-301267. Epub 2011 Jan 24.

44.

The p53-target gene puma drives neutrophil-mediated protection against lethal bacterial sepsis.

Garrison SP, Thornton JA, Häcker H, Webby R, Rehg JE, Parganas E, Zambetti GP, Tuomanen EI.

PLoS Pathog. 2010 Dec 23;6(12):e1001240. doi: 10.1371/journal.ppat.1001240.

45.

Does pandemic A/H1N1 virus have the potential to become more pathogenic?

Ilyushina NA, Ducatez MF, Rehg JE, Marathe BM, Marjuki H, Bovin NV, Webster RG, Webby RJ.

MBio. 2010 Nov 16;1(5). pii: e00249-10. doi: 10.1128/mBio.00249-10.

46.

IL-35-mediated induction of a potent regulatory T cell population.

Collison LW, Chaturvedi V, Henderson AL, Giacomin PR, Guy C, Bankoti J, Finkelstein D, Forbes K, Workman CJ, Brown SA, Rehg JE, Jones ML, Ni HT, Artis D, Turk MJ, Vignali DA.

Nat Immunol. 2010 Dec;11(12):1093-101. doi: 10.1038/ni.1952. Epub 2010 Oct 17.

47.

Pantothenate kinase 1 is required to support the metabolic transition from the fed to the fasted state.

Leonardi R, Rehg JE, Rock CO, Jackowski S.

PLoS One. 2010 Jun 14;5(6):e11107. doi: 10.1371/journal.pone.0011107.

48.

Effect of neuraminidase inhibitor-resistant mutations on pathogenicity of clade 2.2 A/Turkey/15/06 (H5N1) influenza virus in ferrets.

Ilyushina NA, Seiler JP, Rehg JE, Webster RG, Govorkova EA.

PLoS Pathog. 2010 May 27;6(5):e1000933. doi: 10.1371/journal.ppat.1000933.

49.

Emu-BCL10 mice exhibit constitutive activation of both canonical and noncanonical NF-kappaB pathways generating marginal zone (MZ) B-cell expansion as a precursor to splenic MZ lymphoma.

Li Z, Wang H, Xue L, Shin DM, Roopenian D, Xu W, Qi CF, Sangster MY, Orihuela CJ, Tuomanen E, Rehg JE, Cui X, Zhang Q, Morse HC 3rd, Morris SW.

Blood. 2009 Nov 5;114(19):4158-68. doi: 10.1182/blood-2008-12-192583. Epub 2009 Aug 20.

50.

The MDM2-a splice variant of MDM2 alters transformation in vitro and the tumor spectrum in both Arf- and p53-null models of tumorigenesis.

Volk EL, Fan L, Schuster K, Rehg JE, Harris LC.

Mol Cancer Res. 2009 Jun;7(6):863-9. doi: 10.1158/1541-7786.MCR-08-0418. Epub 2009 Jun 2.

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