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Items: 30


Developmental mechanisms and adult stem cells for therapeutic lung regeneration.

Lee JH, Rawlins EL.

Dev Biol. 2018 Jan 15;433(2):166-176. doi: 10.1016/j.ydbio.2017.09.016. Epub 2017 Dec 25. Review.


Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids.

Nikolić MZ, Caritg O, Jeng Q, Johnson JA, Sun D, Howell KJ, Brady JL, Laresgoiti U, Allen G, Butler R, Zilbauer M, Giangreco A, Rawlins EL.

Elife. 2017 Jun 30;6. pii: e26575. doi: 10.7554/eLife.26575.


Lung Organoids and Their Use To Study Cell-Cell Interaction.

Nikolić MZ, Rawlins EL.

Curr Pathobiol Rep. 2017;5(2):223-231. doi: 10.1007/s40139-017-0137-7. Epub 2017 Apr 24. Review.


Cancer: Tumours build their niche.

Huch M, Rawlins EL.

Nature. 2017 May 18;545(7654):292-293. doi: 10.1038/nature22494. Epub 2017 May 10. No abstract available.


FGFR2 is required for airway basal cell self-renewal and terminal differentiation.

Balasooriya GI, Goschorska M, Piddini E, Rawlins EL.

Development. 2017 May 1;144(9):1600-1606. doi: 10.1242/dev.135681. Epub 2017 Mar 27.


SOX2 Drives Bronchial Dysplasia in a Novel Organotypic Model of Early Human Squamous Lung Cancer.

Correia LL, Johnson JA, McErlean P, Bauer J, Farah H, Rassl DM, Rintoul RC, Sethi T, Lavender P, Rawlins EL, Littlewood TD, Evan GI, McCaughan FM.

Am J Respir Crit Care Med. 2017 Jun 1;195(11):1494-1508. doi: 10.1164/rccm.201510-2084OC.


Synthetic scaffolds help airway cells reach maturity.

Nikolić MZ, Rawlins EL.

Elife. 2016 Nov 1;5. pii: e21786. doi: 10.7554/eLife.21786.


Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate.

Laresgoiti U, Nikolić MZ, Rao C, Brady JL, Richardson RV, Batchen EJ, Chapman KE, Rawlins EL.

Development. 2016 Oct 15;143(20):3686-3699. Epub 2016 Aug 30.


Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing.

Rognoni E, Gomez C, Pisco AO, Rawlins EL, Simons BD, Watt FM, Driskell RR.

Development. 2016 Jul 15;143(14):2522-35. doi: 10.1242/dev.131797. Epub 2016 Jun 10.


Mechanical cell competition kills cells via induction of lethal p53 levels.

Wagstaff L, Goschorska M, Kozyrska K, Duclos G, Kucinski I, Chessel A, Hampton-O'Neil L, Bradshaw CR, Allen GE, Rawlins EL, Silberzan P, Carazo Salas RE, Piddini E.

Nat Commun. 2016 Apr 25;7:11373. doi: 10.1038/ncomms11373.


An FGFR1-SPRY2 Signaling Axis Limits Basal Cell Proliferation in the Steady-State Airway Epithelium.

Balasooriya GI, Johnson JA, Basson MA, Rawlins EL.

Dev Cell. 2016 Apr 4;37(1):85-97. doi: 10.1016/j.devcel.2016.03.001.


Clonal Dynamics Reveal Two Distinct Populations of Basal Cells in Slow-Turnover Airway Epithelium.

Watson JK, Rulands S, Wilkinson AC, Wuidart A, Ousset M, Van Keymeulen A, Göttgens B, Blanpain C, Simons BD, Rawlins EL.

Cell Rep. 2015 Jul 7;12(1):90-101. doi: 10.1016/j.celrep.2015.06.011. Epub 2015 Jun 25.


Stem cells: Emergency back-up for lung repair.

Rawlins EL.

Nature. 2015 Jan 29;517(7536):556-7. doi: 10.1038/517556a. No abstract available.


The best laid schemes of airway repair.

Rawlins EL, Giangreco A.

Eur Respir J. 2014 Aug;44(2):299-301. doi: 10.1183/09031936.00088014. No abstract available.


The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells.

Hoyler T, Klose CS, Souabni A, Turqueti-Neves A, Pfeifer D, Rawlins EL, Voehringer D, Busslinger M, Diefenbach A.

Immunity. 2012 Oct 19;37(4):634-48. doi: 10.1016/j.immuni.2012.06.020. Epub 2012 Oct 11.


The a"MAZE"ing world of lung-specific transgenic mice.

Rawlins EL, Perl AK.

Am J Respir Cell Mol Biol. 2012 Mar;46(3):269-82. doi: 10.1165/rcmb.2011-0372PS. Epub 2011 Dec 28. Review.


A 10-gene progenitor cell signature predicts poor prognosis in lung adenocarcinoma.

Onaitis M, D'Amico TA, Clark CP, Guinney J, Harpole DH, Rawlins EL.

Ann Thorac Surg. 2011 Apr;91(4):1046-50; discussion 1050. doi: 10.1016/j.athoracsur.2010.12.054. Epub 2011 Feb 25.


The building blocks of mammalian lung development.

Rawlins EL.

Dev Dyn. 2011 Mar;240(3):463-76. doi: 10.1002/dvdy.22482. Epub 2010 Nov 18. Review.


The Id2+ distal tip lung epithelium contains individual multipotent embryonic progenitor cells.

Rawlins EL, Clark CP, Xue Y, Hogan BL.

Development. 2009 Nov;136(22):3741-5. doi: 10.1242/dev.037317.


Basal cells as stem cells of the mouse trachea and human airway epithelium.

Rock JR, Onaitis MW, Rawlins EL, Lu Y, Clark CP, Xue Y, Randell SH, Hogan BL.

Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12771-5. doi: 10.1073/pnas.0906850106. Epub 2009 Jul 22.


The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium.

Rawlins EL, Okubo T, Xue Y, Brass DM, Auten RL, Hasegawa H, Wang F, Hogan BL.

Cell Stem Cell. 2009 Jun 5;4(6):525-34. doi: 10.1016/j.stem.2009.04.002.


Epithelial stem/progenitor cells in lung postnatal growth, maintenance, and repair.

Rawlins EL, Okubo T, Que J, Xue Y, Clark C, Luo X, Hogan BL.

Cold Spring Harb Symp Quant Biol. 2008;73:291-5. doi: 10.1101/sqb.2008.73.037. Epub 2008 Nov 21. Review.


Lung epithelial progenitor cells: lessons from development.

Rawlins EL.

Proc Am Thorac Soc. 2008 Aug 15;5(6):675-81. doi: 10.1513/pats.200801-006AW. Review.


Ciliated epithelial cell lifespan in the mouse trachea and lung.

Rawlins EL, Hogan BL.

Am J Physiol Lung Cell Mol Physiol. 2008 Jul;295(1):L231-4. doi: 10.1152/ajplung.90209.2008. Epub 2008 May 16.


Lung development and repair: contribution of the ciliated lineage.

Rawlins EL, Ostrowski LE, Randell SH, Hogan BL.

Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):410-7. Epub 2006 Dec 28.


Epithelial stem cells of the lung: privileged few or opportunities for many?

Rawlins EL, Hogan BL.

Development. 2006 Jul;133(13):2455-65. Epub 2006 May 30. Review.


Echinoid facilitates Notch pathway signalling during Drosophila neurogenesis through functional interaction with Delta.

Rawlins EL, Lovegrove B, Jarman AP.

Development. 2003 Dec;130(26):6475-84. Epub 2003 Nov 19.


Mitogens match cell numbers to local demand.

Rawlins EL, Jarman AP.

Trends Cell Biol. 2001 Jul;11(7):277-8.


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