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Items: 18

1.

CRISPR-Cas9-based treatment of myocilin-associated glaucoma.

Jain A, Zode G, Kasetti RB, Ran FA, Yan W, Sharma TP, Bugge K, Searby CC, Fingert JH, Zhang F, Clark AF, Sheffield VC.

Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):11199-11204. doi: 10.1073/pnas.1706193114. Epub 2017 Oct 2.

2.

Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems.

Yamada M, Watanabe Y, Gootenberg JS, Hirano H, Ran FA, Nakane T, Ishitani R, Zhang F, Nishimasu H, Nureki O.

Mol Cell. 2017 Mar 16;65(6):1109-1121.e3. doi: 10.1016/j.molcel.2017.02.007.

3.

Adaptation of CRISPR nucleases for eukaryotic applications.

Ran FA.

Anal Biochem. 2017 Sep 1;532:90-94. doi: 10.1016/j.ab.2016.10.018. Epub 2016 Oct 27. Review. No abstract available.

PMID:
27984015
4.

In vivo gene editing in dystrophic mouse muscle and muscle stem cells.

Tabebordbar M, Zhu K, Cheng JKW, Chew WL, Widrick JJ, Yan WX, Maesner C, Wu EY, Xiao R, Ran FA, Cong L, Zhang F, Vandenberghe LH, Church GM, Wagers AJ.

Science. 2016 Jan 22;351(6271):407-411. doi: 10.1126/science.aad5177. Epub 2015 Dec 31.

5.

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.

Nelson CE, Hakim CH, Ousterout DG, Thakore PI, Moreb EA, Castellanos Rivera RM, Madhavan S, Pan X, Ran FA, Yan WX, Asokan A, Zhang F, Duan D, Gersbach CA.

Science. 2016 Jan 22;351(6271):403-7. doi: 10.1126/science.aad5143. Epub 2015 Dec 31.

6.

Crystal Structure of Staphylococcus aureus Cas9.

Nishimasu H, Cong L, Yan WX, Ran FA, Zetsche B, Li Y, Kurabayashi A, Ishitani R, Zhang F, Nureki O.

Cell. 2015 Aug 27;162(5):1113-26. doi: 10.1016/j.cell.2015.08.007.

7.

In vivo genome editing using Staphylococcus aureus Cas9.

Ran FA, Cong L, Yan WX, Scott DA, Gootenberg JS, Kriz AJ, Zetsche B, Shalem O, Wu X, Makarova KS, Koonin EV, Sharp PA, Zhang F.

Nature. 2015 Apr 9;520(7546):186-91. doi: 10.1038/nature14299. Epub 2015 Apr 1.

8.

Age- and pregnancy-associated DNA methylation changes in mammary epithelial cells.

Huh SJ, Clement K, Jee D, Merlini A, Choudhury S, Maruyama R, Yoo R, Chytil A, Boyle P, Ran FA, Moses HL, Barcellos-Hoff MH, Jackson-Grusby L, Meissner A, Polyak K.

Stem Cell Reports. 2015 Feb 10;4(2):297-311. doi: 10.1016/j.stemcr.2014.12.009. Epub 2015 Jan 22.

9.

Common genetic variants modulate pathogen-sensing responses in human dendritic cells.

Lee MN, Ye C, Villani AC, Raj T, Li W, Eisenhaure TM, Imboywa SH, Chipendo PI, Ran FA, Slowikowski K, Ward LD, Raddassi K, McCabe C, Lee MH, Frohlich IY, Hafler DA, Kellis M, Raychaudhuri S, Zhang F, Stranger BE, Benoist CO, De Jager PL, Regev A, Hacohen N.

Science. 2014 Mar 7;343(6175):1246980. doi: 10.1126/science.1246980.

10.

RNA-guided genome editing of mammalian cells.

Pyzocha NK, Ran FA, Hsu PD, Zhang F.

Methods Mol Biol. 2014;1114:269-77. doi: 10.1007/978-1-62703-761-7_17.

PMID:
24557909
11.

Crystal structure of Cas9 in complex with guide RNA and target DNA.

Nishimasu H, Ran FA, Hsu PD, Konermann S, Shehata SI, Dohmae N, Ishitani R, Zhang F, Nureki O.

Cell. 2014 Feb 27;156(5):935-49. doi: 10.1016/j.cell.2014.02.001. Epub 2014 Feb 13.

12.

Genome engineering using the CRISPR-Cas9 system.

Ran FA, Hsu PD, Wright J, Agarwala V, Scott DA, Zhang F.

Nat Protoc. 2013 Nov;8(11):2281-2308. doi: 10.1038/nprot.2013.143. Epub 2013 Oct 24.

13.

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity.

Ran FA, Hsu PD, Lin CY, Gootenberg JS, Konermann S, Trevino AE, Scott DA, Inoue A, Matoba S, Zhang Y, Zhang F.

Cell. 2013 Sep 12;154(6):1380-9. doi: 10.1016/j.cell.2013.08.021. Epub 2013 Aug 29. Erratum in: Cell. 2013 Oct 10;155(2):479-80.

14.

DNA targeting specificity of RNA-guided Cas9 nucleases.

Hsu PD, Scott DA, Weinstein JA, Ran FA, Konermann S, Agarwala V, Li Y, Fine EJ, Wu X, Shalem O, Cradick TJ, Marraffini LA, Bao G, Zhang F.

Nat Biotechnol. 2013 Sep;31(9):827-32. doi: 10.1038/nbt.2647. Epub 2013 Jul 21.

15.

Multiplex genome engineering using CRISPR/Cas systems.

Cong L, Ran FA, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA, Zhang F.

Science. 2013 Feb 15;339(6121):819-23. doi: 10.1126/science.1231143. Epub 2013 Jan 3.

16.

Physiological and transcriptomic characterization of a fliA mutant of Pseudomonas putida KT2440.

Rodríguez-Herva JJ, Duque E, Molina-Henares MA, Navarro-Avilés G, Van Dillewijn P, De La Torre J, Molina-Henares AJ, La Campa AS, Ran FA, Segura A, Shingler V, Ramos JL.

Environ Microbiol Rep. 2010 Jun;2(3):373-80. doi: 10.1111/j.1758-2229.2009.00084.x. Epub 2009 Oct 7.

PMID:
23766109
17.

Deletion mutations caused by DNA strand slippage in Acinetobacter baylyi.

Gore JM, Ran FA, Ornston LN.

Appl Environ Microbiol. 2006 Aug;72(8):5239-45.

18.

Miniature protein inhibitors of the p53-hDM2 interaction.

Kritzer JA, Zutshi R, Cheah M, Ran FA, Webman R, Wongjirad TM, Schepartz A.

Chembiochem. 2006 Jan;7(1):29-31. No abstract available.

PMID:
16397877

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