Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 124


Metaboloptics: Visualization of the tumor functional landscape via metabolic and vascular imaging.

Martinez AF, McCachren SS 3rd, Lee M, Murphy HA, Zhu C, Crouch BT, Martin HL, Erkanli A, Rajaram N, Ashcraft KA, Fontanella AN, Dewhirst MW, Ramanujam N.

Sci Rep. 2018 Mar 8;8(1):4171. doi: 10.1038/s41598-018-22480-w.


An integrated strategy for improving contrast, durability, and portability of a Pocket Colposcope for cervical cancer screening and diagnosis.

Lam CT, Mueller J, Asma B, Asiedu M, Krieger MS, Chitalia R, Dahl D, Taylor P, Schmitt JW, Ramanujam N.

PLoS One. 2018 Feb 9;13(2):e0192530. doi: 10.1371/journal.pone.0192530. eCollection 2018.


Serum apolipoprotein A1 and haptoglobin, in patients with suspected drug-induced liver injury (DILI) as biomarkers of recovery.

Peta V, Tse C, Perazzo H, Munteanu M, Ngo Y, Ngo A, Ramanujam N, Verglas L, Mallet M, Ratziu V, Thabut D, Rudler M, Thibault V, Schuppe-Koistinen I, Bonnefont-Rousselot D, Hainque B, Imbert-Bismut F, Merz M, Kullak-Ublick G, Andrade R, van Boemmel F, Schott E, Poynard T; Drug Induced Liver Injury- Groupe Hospitalier Pitié-Salpêtrière; Drug Induced Liver Group of the Injury Safer and Faster Evidence-based Translation consortium.

PLoS One. 2017 Dec 29;12(12):e0189436. doi: 10.1371/journal.pone.0189436. eCollection 2017.


Leveraging ectopic Hsp90 expression to assay the presence of tumor cells and aggressive tumor phenotypes in breast specimens.

Crouch B, Murphy H, Belonwu S, Martinez A, Gallagher J, Hall A, Soo MS, Lee M, Hughes P, Haystead T, Ramanujam N.

Sci Rep. 2017 Dec 13;7(1):17487. doi: 10.1038/s41598-017-17832-x.


Near-simultaneous intravital microscopy of glucose uptake and mitochondrial membrane potential, key endpoints that reflect major metabolic axes in cancer.

Zhu C, Martinez AF, Martin HL, Li M, Crouch BT, Carlson DA, Haystead TAJ, Ramanujam N.

Sci Rep. 2017 Oct 23;7(1):13772. doi: 10.1038/s41598-017-14226-x.


Distinct Angiogenic Changes during Carcinogenesis Defined by Novel Label-Free Dark-Field Imaging in a Hamster Cheek Pouch Model.

Hu F, Martin H, Martinez A, Everitt J, Erkanli A, Lee WT, Dewhirst M, Ramanujam N.

Cancer Res. 2017 Dec 15;77(24):7109-7119. doi: 10.1158/0008-5472.CAN-17-1058. Epub 2017 Oct 11.


Development of enhanced ethanol ablation as an alternative to surgery in treatment of superficial solid tumors.

Morhard R, Nief C, Barrero Castedo C, Hu F, Madonna M, Mueller JL, Dewhirst MW, Katz DF, Ramanujam N.

Sci Rep. 2017 Aug 18;7(1):8750. doi: 10.1038/s41598-017-09371-2.


Design and preliminary analysis of a vaginal inserter for speculum-free cervical cancer screening.

Asiedu MN, Agudogo J, Krieger MS, Miros R, Proeschold-Bell RJ, Schmitt JW, Ramanujam N.

PLoS One. 2017 May 31;12(5):e0177782. doi: 10.1371/journal.pone.0177782. eCollection 2017.


Fast and parallel determination of PCB 77 and PCB 180 in plasma using ultra performance liquid chromatography with diode array detection: A pharmacokinetic study in Swiss albino mouse.

Ramanujam N, Sivaselvakumar M, Ramalingam S.

Biomed Chromatogr. 2017 Nov;31(11). doi: 10.1002/bmc.4000. Epub 2017 Jun 5.


International Image Concordance Study to Compare a Point-of-Care Tampon Colposcope With a Standard-of-Care Colposcope.

Mueller JL, Asma E, Lam CT, Krieger MS, Gallagher JE, Erkanli A, Hariprasad R, Malliga JS, Muasher LC, Mchome B, Oneko O, Taylor P, Venegas G, Wanyoro A, Mehrotra R, Schmitt JW, Ramanujam N.

J Low Genit Tract Dis. 2017 Apr;21(2):112-119. doi: 10.1097/LGT.0000000000000306.


Miniature spectral imaging device for wide-field quantitative functional imaging of the morphological landscape of breast tumor margins.

Nichols BS, Llopis A, Palmer GM, McCachren SS 3rd, Senlik O, Miller D, Brooke MA, Jokerst NM, Geradts J, Greenup R, Ramanujam N.

J Biomed Opt. 2017 Feb 1;22(2):26007. doi: 10.1117/1.JBO.22.2.026007.


Algorithms for differentiating between images of heterogeneous tissue across fluorescence microscopes.

Chitalia R, Mueller J, Fu HL, Whitley MJ, Kirsch DG, Brown JQ, Willett R, Ramanujam N.

Biomed Opt Express. 2016 Aug 12;7(9):3412-3424. eCollection 2016 Sep 1.


Dark field optical imaging reveals vascular changes in an inducible hamster cheek pouch model during carcinogenesis.

Hu F, Morhard R, Murphy HA, Zhu C, Ramanujam N.

Biomed Opt Express. 2016 Aug 5;7(9):3247-3261. eCollection 2016 Sep 1.


Oxygen and Perfusion Kinetics in Response to Fractionated Radiation Therapy in FaDu Head and Neck Cancer Xenografts Are Related to Treatment Outcome.

Hu F, Vishwanath K, Salama JK, Erkanli A, Peterson B, Oleson JR, Lee WT, Brizel DM, Ramanujam N, Dewhirst MW.

Int J Radiat Oncol Biol Phys. 2016 Oct 1;96(2):462-469. doi: 10.1016/j.ijrobp.2016.06.007. Epub 2016 Jun 14.


Correlation of breast tissue histology and optical signatures to improve margin assessment techniques.

Kennedy S, Caldwell M, Bydlon T, Mulvey C, Mueller J, Wilke L, Barry W, Ramanujam N, Geradts J.

J Biomed Opt. 2016 Jun 1;21(6):66014. doi: 10.1117/1.JBO.21.6.066014. No abstract available.


The Lymphatic Endothelial mCLCA1 Antibody Induces Proliferation and Growth of Lymph Node Lymphatic Sinuses.

Jordan-Williams KL, Ramanujam N, Farr AG, Ruddell A.

PLoS One. 2016 May 25;11(5):e0156079. doi: 10.1371/journal.pone.0156079. eCollection 2016.


Rapid staining and imaging of subnuclear features to differentiate between malignant and benign breast tissues at a point-of-care setting.

Mueller JL, Gallagher JE, Chitalia R, Krieger M, Erkanli A, Willett RM, Geradts J, Ramanujam N.

J Cancer Res Clin Oncol. 2016 Jul;142(7):1475-86. doi: 10.1007/s00432-016-2165-9. Epub 2016 Apr 22.


An Automatic Multidocument Text Summarization Approach Based on Naïve Bayesian Classifier Using Timestamp Strategy.

Ramanujam N, Kaliappan M.

ScientificWorldJournal. 2016;2016:1784827. doi: 10.1155/2016/1784827. Epub 2016 Feb 29.


A Fluorescence-Guided Laser Ablation System for Removal of Residual Cancer in a Mouse Model of Soft Tissue Sarcoma.

Lazarides AL, Whitley MJ, Strasfeld DB, Cardona DM, Ferrer JM, Mueller JL, Fu HL, Bartholf DeWitt S, Brigman BE, Ramanujam N, Kirsch DG, Eward WC.

Theranostics. 2016 Jan 1;6(2):155-66. doi: 10.7150/thno.13536. eCollection 2016.


Structured Illumination Microscopy and a Quantitative Image Analysis for the Detection of Positive Margins in a Pre-Clinical Genetically Engineered Mouse Model of Sarcoma.

Fu HL, Mueller JL, Whitley MJ, Cardona DM, Willett RM, Kirsch DG, Brown JQ, Ramanujam N.

PLoS One. 2016 Jan 22;11(1):e0147006. doi: 10.1371/journal.pone.0147006. eCollection 2016.


Design of a Novel Low Cost Point of Care Tampon (POCkeT) Colposcope for Use in Resource Limited Settings.

Lam CT, Krieger MS, Gallagher JE, Asma B, Muasher LC, Schmitt JW, Ramanujam N.

PLoS One. 2015 Sep 2;10(9):e0135869. doi: 10.1371/journal.pone.0135869. eCollection 2015.


Micro-anatomical quantitative optical imaging: toward automated assessment of breast tissues.

Dobbs JL, Mueller JL, Krishnamurthy S, Shin D, Kuerer H, Yang W, Ramanujam N, Richards-Kortum R.

Breast Cancer Res. 2015 Aug 20;17:105. doi: 10.1186/s13058-015-0617-9.


A Quantitative Diffuse Reflectance Imaging (QDRI) System for Comprehensive Surveillance of the Morphological Landscape in Breast Tumor Margins.

Nichols BS, Schindler CE, Brown JQ, Wilke LG, Mulvey CS, Krieger MS, Gallagher J, Geradts J, Greenup RA, Von Windheim JA, Ramanujam N.

PLoS One. 2015 Jun 15;10(6):e0127525. doi: 10.1371/journal.pone.0127525. eCollection 2015.


Light for Life: International Year of Light 2015.

Leitgeb RA, Andersen PE, Popp J, Ramanujam N, Svanberg K.

J Biomed Opt. 2015 Jun;20(6):061101. doi: 10.1117/1.JBO.20.6.061101. No abstract available.


A quantitative microscopic approach to predict local recurrence based on in vivo intraoperative imaging of sarcoma tumor margins.

Mueller JL, Fu HL, Mito JK, Whitley MJ, Chitalia R, Erkanli A, Dodd L, Cardona DM, Geradts J, Willett RM, Kirsch DG, Ramanujam N.

Int J Cancer. 2015 Nov 15;137(10):2403-12. doi: 10.1002/ijc.29611. Epub 2015 Jun 3.


Non-invasive, simultaneous quantification of vascular oxygenation and glucose uptake in tissue.

Rajaram N, Reesor AF, Mulvey CS, Frees AE, Ramanujam N.

PLoS One. 2015 Jan 30;10(1):e0117132. doi: 10.1371/journal.pone.0117132. eCollection 2015.


Delivery-corrected imaging of fluorescently-labeled glucose reveals distinct metabolic phenotypes in murine breast cancer.

Frees AE, Rajaram N, McCachren SS 3rd, Fontanella AN, Dewhirst MW, Ramanujam N.

PLoS One. 2014 Dec 19;9(12):e115529. doi: 10.1371/journal.pone.0115529. eCollection 2014.


Assessment of the sensitivity and specificity of tissue-specific-based and anatomical-based optical biomarkers for rapid detection of human head and neck squamous cell carcinoma.

Hu F, Vishwanath K, Beumer HW, Puscas L, Afshari HR, Esclamado RM, Scher R, Fisher S, Lo J, Mulvey C, Ramanujam N, Lee WT.

Oral Oncol. 2014 Sep;50(9):848-856. doi: 10.1016/j.oraloncology.2014.06.015. Epub 2014 Jul 16.


Chromophore based analyses of steady-state diffuse reflectance spectroscopy: current status and perspectives for clinical adoption.

Bydlon TM, Nachabé R, Ramanujam N, Sterenborg HJ, Hendriks BH.

J Biophotonics. 2015 Jan;8(1-2):9-24. doi: 10.1002/jbio.201300198. Epub 2014 Apr 23. Review.


Rapid determination of oxygen saturation and vascularity for cancer detection.

Hu F, Vishwanath K, Lo J, Erkanli A, Mulvey C, Lee WT, Ramanujam N.

PLoS One. 2013 Dec 16;8(12):e82977. doi: 10.1371/journal.pone.0082977. eCollection 2013.


Delivery rate affects uptake of a fluorescent glucose analog in murine metastatic breast cancer.

Rajaram N, Frees AE, Fontanella AN, Zhong J, Hansen K, Dewhirst MW, Ramanujam N.

PLoS One. 2013 Oct 18;8(10):e76524. doi: 10.1371/journal.pone.0076524. eCollection 2013.


Optical and radioiodinated tethered Hsp90 inhibitors reveal selective internalization of ectopic Hsp90 in malignant breast tumor cells.

Barrott JJ, Hughes PF, Osada T, Yang XY, Hartman ZC, Loiselle DR, Spector NL, Neckers L, Rajaram N, Hu F, Ramanujam N, Vaidyanathan G, Zalutsky MR, Lyerly HK, Haystead TA.

Chem Biol. 2013 Sep 19;20(9):1187-97. doi: 10.1016/j.chembiol.2013.08.004. Epub 2013 Sep 12.


Optical spectral surveillance of breast tissue landscapes for detection of residual disease in breast tumor margins.

Brown JQ, Bydlon TM, Kennedy SA, Caldwell ML, Gallagher JE, Junker M, Wilke LG, Barry WT, Geradts J, Ramanujam N.

PLoS One. 2013 Jul 26;8(7):e69906. doi: 10.1371/journal.pone.0069906. Print 2013.


Optimization of a widefield structured illumination microscope for non-destructive assessment and quantification of nuclear features in tumor margins of a primary mouse model of sarcoma.

Fu HL, Mueller JL, Javid MP, Mito JK, Kirsch DG, Ramanujam N, Brown JQ.

PLoS One. 2013 Jul 23;8(7):e68868. doi: 10.1371/journal.pone.0068868. Print 2013.


Quantitative Segmentation of Fluorescence Microscopy Images of Heterogeneous Tissue: Application to the Detection of Residual Disease in Tumor Margins.

Mueller JL, Harmany ZT, Mito JK, Kennedy SA, Kim Y, Dodd L, Geradts J, Kirsch DG, Willett RM, Brown JQ, Ramanujam N.

PLoS One. 2013 Jun 18;8(6):e66198. doi: 10.1371/journal.pone.0066198. Print 2013.


Wavelength optimization for quantitative spectral imaging of breast tumor margins.

Lo JY, Brown JQ, Dhar S, Yu B, Palmer GM, Jokerst NM, Ramanujam N.

PLoS One. 2013 Apr 16;8(4):e61767. doi: 10.1371/journal.pone.0061767. Print 2013.


Radiation induces aerobic glycolysis through reactive oxygen species.

Zhong J, Rajaram N, Brizel DM, Frees AE, Ramanujam N, Batinic-Haberle I, Dewhirst MW.

Radiother Oncol. 2013 Mar;106(3):390-6. doi: 10.1016/j.radonc.2013.02.013. Epub 2013 Mar 28.


Advancing optical imaging for breast margin assessment: an analysis of excisional time, cautery, and patent blue dye on underlying sources of contrast.

Bydlon TM, Barry WT, Kennedy SA, Brown JQ, Gallagher JE, Wilke LG, Geradts J, Ramanujam N.

PLoS One. 2012;7(12):e51418. doi: 10.1371/journal.pone.0051418. Epub 2012 Dec 10.


A diffuse reflectance spectral imaging system for tumor margin assessment using custom annular photodiode arrays.

Dhar S, Lo JY, Palmer GM, Brooke MA, Nichols BS, Yu B, Ramanujam N, Jokerst NM.

Biomed Opt Express. 2012 Dec 1;3(12):3211-22. doi: 10.1364/BOE.3.003211. Epub 2012 Nov 8.


Measuring tumor cycling hypoxia and angiogenesis using a side-firing fiber optic probe.

Yu B, Shah A, Wang B, Rajaram N, Wang Q, Ramanujam N, Palmer GM, Dewhirst MW.

J Biophotonics. 2014 Jul;7(7):552-64. doi: 10.1002/jbio.201200187. Epub 2012 Dec 14.


Real time identification of drug-induced liver injury (DILI) through daily screening of ALT results: a prospective pilot cohort study.

M'Kada H, Perazzo H, Munteanu M, Ngo Y, Ramanujam N, Fautrel B, Imbert-Bismut F, Ratziu V, Schuppe-Koistinen I, Leblond V, Delattre JY, Samson Y, Caen OL, Bricaire F, Khayat D, Pierrot-Deseilligny C, Herson S, Amoura Z, Tilleul P, Deckmyn O, Coriat P, Delpech VN, Boulogne P, Bonnefont-Rousselot D, Poynard T; Drug Induced Liver Injury Groupe Hospitalier Pitié-Salpêtrière Group; Safer and Faster Evidence-based Translation Consortium.

PLoS One. 2012;7(8):e42418. Epub 2012 Aug 14.


Experimental validation of an inverse fluorescence Monte Carlo model to extract concentrations of metabolically relevant fluorophores from turbid phantoms and a murine tumor model.

Liu C, Rajaram N, Vishwanath K, Jiang T, Palmer GM, Ramanujam N.

J Biomed Opt. 2012 Jul;17(7):077012. doi: 10.1117/1.JBO.17.7.077012.


Towards a field-compatible optical spectroscopic device for cervical cancer screening in resource-limited settings: effects of calibration and pressure.

Chang VT, Merisier D, Yu B, Walmer DK, Ramanujam N.

Opt Express. 2011 Sep 12;19(19):17908-24. doi: 10.1364/OE.19.017908.


What are the best reference values for a normal serum alanine transaminase activity (ALT)? Impact on the presumed prevalence of drug induced liver injury (DILI).

M'Kada H, Munteanu M, Perazzo H, Ngo Y, Ramanujam N, Imbert-Bismut F, Ratziu V, Bonnefont-Rousselot D, Souberbielle B, Schuppe-Koistinen I, Poynard T; DILI group of the SAFE-T consortium.

Regul Toxicol Pharmacol. 2011 Aug;60(3):290-5. doi: 10.1016/j.yrtph.2011.04.002. Epub 2011 Apr 24.


Portable, Fiber-Based, Diffuse Reflection Spectroscopy (DRS) Systems for Estimating Tissue Optical Properties.

Vishwanath K, Chang K, Klein D, Deng YF, Chang V, Phelps JE, Ramanujam N.

Appl Spectrosc. 2011 Feb 1;62(2):206-215.


Detection of squamous cell carcinoma and corresponding biomarkers using optical spectroscopy.

Beumer HW, Vishwanath K, Puscas L, Afshari HR, Ramanujam N, Lee WT.

Otolaryngol Head Neck Surg. 2011 Mar;144(3):390-4. doi: 10.1177/0194599810394290. Epub 2011 Jan 28.


Instrument independent diffuse reflectance spectroscopy.

Yu B, Fu HL, Ramanujam N.

J Biomed Opt. 2011 Jan-Feb;16(1):011010. doi: 10.1117/1.3524303.


Optical breast cancer margin assessment: an observational study of the effects of tissue heterogeneity on optical contrast.

Kennedy S, Geradts J, Bydlon T, Brown JQ, Gallagher J, Junker M, Barry W, Ramanujam N, Wilke L.

Breast Cancer Res. 2010;12(6):R91. doi: 10.1186/bcr2770. Epub 2010 Nov 5.


Visible light optical spectroscopy is sensitive to neovascularization in the dysplastic cervix.

Chang VT, Bean SM, Cartwright PS, Ramanujam N.

J Biomed Opt. 2010 Sep-Oct;15(5):057006. doi: 10.1117/1.3495730.


Rapid ratiometric determination of hemoglobin concentration using UV-VIS diffuse reflectance at isosbestic wavelengths.

Phelps JE, Vishwanath K, Chang VT, Ramanujam N.

Opt Express. 2010 Aug 30;18(18):18779-92. doi: 10.1364/OE.18.018779.

Supplemental Content

Loading ...
Support Center