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Items: 17

1.

Sampling the conformational space of the catalytic subunit of human γ-secretase.

Bai XC, Rajendra E, Yang G, Shi Y, Scheres SH.

Elife. 2015 Dec 1;4. pii: e11182. doi: 10.7554/eLife.11182.

2.

Ubiquitin-SUMO circuitry controls activated fanconi anemia ID complex dosage in response to DNA damage.

Gibbs-Seymour I, Oka Y, Rajendra E, Weinert BT, Passmore LA, Patel KJ, Olsen JV, Choudhary C, Bekker-Jensen S, Mailand N.

Mol Cell. 2015 Jan 8;57(1):150-64. doi: 10.1016/j.molcel.2014.12.001. Epub 2014 Dec 31.

3.

Abundance of the Fanconi anaemia core complex is regulated by the RuvBL1 and RuvBL2 AAA+ ATPases.

Rajendra E, Garaycoechea JI, Patel KJ, Passmore LA.

Nucleic Acids Res. 2014 Dec 16;42(22):13736-48. doi: 10.1093/nar/gku1230. Epub 2014 Nov 26.

4.

The genetic and biochemical basis of FANCD2 monoubiquitination.

Rajendra E, Oestergaard VH, Langevin F, Wang M, Dornan GL, Patel KJ, Passmore LA.

Mol Cell. 2014 Jun 5;54(5):858-69. doi: 10.1016/j.molcel.2014.05.001.

5.

Supporting the drive to thrive in cleft lip and palate infant- a case report.

S TR, M M, N S, E RR, A R.

J Clin Diagn Res. 2013 Dec;7(12):3102-4. doi: 10.7860/JCDR/2013/7562.3870. Epub 2013 Dec 15.

6.

Human inositol polyphosphate multikinase regulates transcript-selective nuclear mRNA export to preserve genome integrity.

Wickramasinghe VO, Savill JM, Chavali S, Jonsdottir AB, Rajendra E, Grüner T, Laskey RA, Babu MM, Venkitaraman AR.

Mol Cell. 2013 Sep 26;51(6):737-50. doi: 10.1016/j.molcel.2013.08.031.

7.

A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization.

Jeyasekharan AD, Liu Y, Hattori H, Pisupati V, Jonsdottir AB, Rajendra E, Lee M, Sundaramoorthy E, Schlachter S, Kaminski CF, Ofir-Rosenfeld Y, Sato K, Savill J, Ayoub N, Venkitaraman AR.

Nat Struct Mol Biol. 2013 Oct;20(10):1191-8. doi: 10.1038/nsmb.2666. Epub 2013 Sep 8.

8.

A DNA-damage selective role for BRCA1 E3 ligase in claspin ubiquitylation, CHK1 activation, and DNA repair.

Sato K, Sundaramoorthy E, Rajendra E, Hattori H, Jeyasekharan AD, Ayoub N, Schiess R, Aebersold R, Nishikawa H, Sedukhina AS, Wada H, Ohta T, Venkitaraman AR.

Curr Biol. 2012 Sep 25;22(18):1659-66. doi: 10.1016/j.cub.2012.07.034. Epub 2012 Aug 2.

9.

Interrogation of the protein-protein interactions between human BRCA2 BRC repeats and RAD51 reveals atomistic determinants of affinity.

Cole DJ, Rajendra E, Roberts-Thomson M, Hardwick B, McKenzie GJ, Payne MC, Venkitaraman AR, Skylaris CK.

PLoS Comput Biol. 2011 Jul;7(7):e1002096. doi: 10.1371/journal.pcbi.1002096. Epub 2011 Jul 14.

10.

DNA damage regulates the mobility of Brca2 within the nucleoplasm of living cells.

Jeyasekharan AD, Ayoub N, Mahen R, Ries J, Esposito A, Rajendra E, Hattori H, Kulkarni RP, Venkitaraman AR.

Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21937-42. doi: 10.1073/pnas.1009577107. Epub 2010 Nov 22.

11.

Two modules in the BRC repeats of BRCA2 mediate structural and functional interactions with the RAD51 recombinase.

Rajendra E, Venkitaraman AR.

Nucleic Acids Res. 2010 Jan;38(1):82-96. doi: 10.1093/nar/gkp873. Epub 2009 Oct 29.

12.

1H, 13C and 15N resonance assignments for Binder of Arl2, BART.

Bailey LK, Campbell LJ, Evetts KA, Littlefield K, Rajendra E, Nietlispach D, Owen D, Mott HR.

Biomol NMR Assign. 2009 Jun;3(1):33-6. doi: 10.1007/s12104-008-9135-3. Epub 2008 Dec 16.

PMID:
19636941
13.

The BRC repeats of human BRCA2 differentially regulate RAD51 binding on single- versus double-stranded DNA to stimulate strand exchange.

Shivji MK, Mukund SR, Rajendra E, Chen S, Short JM, Savill J, Klenerman D, Venkitaraman AR.

Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13254-9. doi: 10.1073/pnas.0906208106. Epub 2009 Jul 23.

14.

The carboxyl terminus of Brca2 links the disassembly of Rad51 complexes to mitotic entry.

Ayoub N, Rajendra E, Su X, Jeyasekharan AD, Mahen R, Venkitaraman AR.

Curr Biol. 2009 Jul 14;19(13):1075-85. doi: 10.1016/j.cub.2009.05.057. Epub 2009 Jun 18.

15.

The UPS: a promising target for breast cancer treatment.

Sato K, Rajendra E, Ohta T.

BMC Biochem. 2008 Oct 21;9 Suppl 1:S2. doi: 10.1186/1471-2091-9-S1-S2. Review.

16.

The structure of binder of Arl2 (BART) reveals a novel G protein binding domain: implications for function.

Bailey LK, Campbell LJ, Evetts KA, Littlefield K, Rajendra E, Nietlispach D, Owen D, Mott HR.

J Biol Chem. 2009 Jan 9;284(2):992-9. doi: 10.1074/jbc.M806167200. Epub 2008 Nov 3.

17.

An essential role for Cdk1 in S phase control is revealed via chemical genetics in vertebrate cells.

Hochegger H, Dejsuphong D, Sonoda E, Saberi A, Rajendra E, Kirk J, Hunt T, Takeda S.

J Cell Biol. 2007 Jul 16;178(2):257-68.

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