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Pancreatoduodenectomy with or without prophylactic falciform ligament wrap around the gastroduodenal artery stump for prevention of pancreatectomy hemorrhage.

Müssle B, Zühlke L, Wierick A, Sturm D, Grählert X, Distler M, Rahbari NN, Weitz J, Welsch T.

Trials. 2018 Apr 12;19(1):222. doi: 10.1186/s13063-018-2580-0.


Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2.

Incio J, Ligibel JA, McManus DT, Suboj P, Jung K, Kawaguchi K, Pinter M, Babykutty S, Chin SM, Vardam TD, Huang Y, Rahbari NN, Roberge S, Wang D, Gomes-Santos IL, Puchner SB, Schlett CL, Hoffmman U, Ancukiewicz M, Tolaney SM, Krop IE, Duda DG, Boucher Y, Fukumura D, Jain RK.

Sci Transl Med. 2018 Mar 14;10(432). pii: eaag0945. doi: 10.1126/scitranslmed.aag0945.


Comparison of three classifications for lymph node evaluation in patients undergoing total mesorectal excision for rectal cancer.

Fritzmann J, Contin P, Reissfelder C, Büchler MW, Weitz J, Rahbari NN, Ulrich AB.

Langenbecks Arch Surg. 2018 Mar 9. doi: 10.1007/s00423-018-1662-5. [Epub ahead of print]


Management of clinically relevant postpancreatectomy hemorrhage (PPH) over two decades - A comparative study of 1 450 consecutive patients undergoing pancreatic resection.

Wolk S, Grützmann R, Rahbari NN, Hoffmann RT, Plodeck V, Weitz J, Welsch T, Distler M.

Pancreatology. 2017 Nov - Dec;17(6):943-950. doi: 10.1016/j.pan.2017.10.006. Epub 2017 Oct 25.


Postoperative course and prognostic value of circulating angiogenic cytokines after pancreatic cancer resection.

Yang C, Bork U, Schölch S, Kulu Y, Kaderali L, Bolstorff UL, Kahlert C, Weitz J, Rahbari NN, Reissfelder C.

Oncotarget. 2017 Aug 17;8(42):72315-72323. doi: 10.18632/oncotarget.20315. eCollection 2017 Sep 22.


Time of Metastasis and Outcome in Colorectal Cancer.

Rahbari NN, Carr PR, Jansen L, Chang-Claude J, Weitz J, Hoffmeister M, Brenner H.

Ann Surg. 2017 Oct 23. doi: 10.1097/SLA.0000000000002564. [Epub ahead of print]


Targeting CXCR4-dependent immunosuppressive Ly6Clow monocytes improves antiangiogenic therapy in colorectal cancer.

Jung K, Heishi T, Incio J, Huang Y, Beech EY, Pinter M, Ho WW, Kawaguchi K, Rahbari NN, Chung E, Kim JK, Clark JW, Willett CG, Yun SH, Luster AD, Padera TP, Jain RK, Fukumura D.

Proc Natl Acad Sci U S A. 2017 Sep 26;114(39):10455-10460. doi: 10.1073/pnas.1710754114. Epub 2017 Sep 12.


Surgical salvage of recurrence after resection of colorectal liver metastases: incidence and outcomes.

Rahbari NN, D'Angelica MI.

Hepat Oncol. 2017 Aug 3. doi: 10.2217/hep-2017-0002. [Epub ahead of print]


Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy.

Jung K, Heishi T, Khan OF, Kowalski PS, Incio J, Rahbari NN, Chung E, Clark JW, Willett CG, Luster AD, Yun SH, Langer R, Anderson DG, Padera TP, Jain RK, Fukumura D.

J Clin Invest. 2017 Aug 1;127(8):3039-3051. doi: 10.1172/JCI93182. Epub 2017 Jul 10.


Prognostic value of circulating endothelial cells in metastatic colorectal cancer.

Rahbari NN, Schölch S, Bork U, Kahlert C, Schneider M, Rahbari M, Büchler MW, Weitz J, Reissfelder C.

Oncotarget. 2017 Jun 6;8(23):37491-37501. doi: 10.18632/oncotarget.16397.


Inhibition of Six1 affects tumour invasion and the expression of cancer stem cell markers in pancreatic cancer.

Lerbs T, Bisht S, Schölch S, Pecqueux M, Kristiansen G, Schneider M, Hofmann BT, Welsch T, Reissfelder C, Rahbari NN, Fritzmann J, Brossart P, Weitz J, Feldmann G, Kahlert C.

BMC Cancer. 2017 Apr 7;17(1):249. doi: 10.1186/s12885-017-3225-5.


Use of activity tracking in major visceral surgery-the Enhanced Perioperative Mobilization (EPM) trial: study protocol for a randomized controlled trial.

Wolk S, Meißner T, Linke S, Müssle B, Wierick A, Bogner A, Sturm D, Rahbari NN, Distler M, Weitz J, Welsch T.

Trials. 2017 Feb 21;18(1):77. doi: 10.1186/s13063-017-1782-1.


Reply: What Is the Impact of Intraoperative Re-resection After a Positive Pancreatic Margin Frozen Section in the Era of Perioperative Therapies?

Nitschke P, Weitz J, Rahbari NN.

Ann Surg. 2018 Mar;267(3):e56. doi: 10.1097/SLA.0000000000002130. No abstract available.


Anti-VEGF therapy induces ECM remodeling and mechanical barriers to therapy in colorectal cancer liver metastases.

Rahbari NN, Kedrin D, Incio J, Liu H, Ho WW, Nia HT, Edrich CM, Jung K, Daubriac J, Chen I, Heishi T, Martin JD, Huang Y, Maimon N, Reissfelder C, Weitz J, Boucher Y, Clark JW, Grodzinsky AJ, Duda DG, Jain RK, Fukumura D.

Sci Transl Med. 2016 Oct 12;8(360):360ra135.


LDB1 overexpression is a negative prognostic factor in colorectal cancer.

García SA, Swiersy A, Radhakrishnan P, Branchi V, Kanth Nanduri L, Győrffy B, Betzler AM, Bork U, Kahlert C, Reißfelder C, Rahbari NN, Weitz J, Schölch S.

Oncotarget. 2016 Dec 20;7(51):84258-84270. doi: 10.18632/oncotarget.12481.


Impact of Intraoperative Re-resection to Achieve R0 Status on Survival in Patients With Pancreatic Cancer: A Single-center Experience With 483 Patients.

Nitschke P, Volk A, Welsch T, Hackl J, Reissfelder C, Rahbari M, Distler M, Saeger HD, Weitz J, Rahbari NN.

Ann Surg. 2017 Jun;265(6):1219-1225. doi: 10.1097/SLA.0000000000001808.


Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy.

Incio J, Liu H, Suboj P, Chin SM, Chen IX, Pinter M, Ng MR, Nia HT, Grahovac J, Kao S, Babykutty S, Huang Y, Jung K, Rahbari NN, Han X, Chauhan VP, Martin JD, Kahn J, Huang P, Desphande V, Michaelson J, Michelakos TP, Ferrone CR, Soares R, Boucher Y, Fukumura D, Jain RK.

Cancer Discov. 2016 Aug;6(8):852-69. doi: 10.1158/2159-8290.CD-15-1177. Epub 2016 May 31.


Circulating tumor cells exhibit stem cell characteristics in an orthotopic mouse model of colorectal cancer.

Schölch S, García SA, Iwata N, Niemietz T, Betzler AM, Nanduri LK, Bork U, Kahlert C, Thepkaysone ML, Swiersy A, Büchler MW, Reissfelder C, Weitz J, Rahbari NN.

Oncotarget. 2016 May 10;7(19):27232-42. doi: 10.18632/oncotarget.8373.


Impact of Bevacizumab on parenchymal damage and functional recovery of the liver in patients with colorectal liver metastases.

Volk AM, Fritzmann J, Reissfelder C, Weber GF, Weitz J, Rahbari NN.

BMC Cancer. 2016 Feb 10;16:84. doi: 10.1186/s12885-016-2095-6.


PlGF/VEGFR-1 Signaling Promotes Macrophage Polarization and Accelerated Tumor Progression in Obesity.

Incio J, Tam J, Rahbari NN, Suboj P, McManus DT, Chin SM, Vardam TD, Batista A, Babykutty S, Jung K, Khachatryan A, Hato T, Ligibel JA, Krop IE, Puchner SB, Schlett CL, Hoffmman U, Ancukiewicz M, Shibuya M, Carmeliet P, Soares R, Duda DG, Jain RK, Fukumura D.

Clin Cancer Res. 2016 Jun 15;22(12):2993-3004. doi: 10.1158/1078-0432.CCR-15-1839. Epub 2016 Feb 9.


Metastatic Spread Emerging From Liver Metastases of Colorectal Cancer: Does the Seed Leave the Soil Again?

Rahbari NN, Bork U, Schölch S, Reissfelder C, Thorlund K, Betzler A, Kahlert C, Schneider M, Ulrich AB, Büchler MW, Weitz J, Koch M.

Ann Surg. 2016 Feb;263(2):345-52. doi: 10.1097/SLA.0000000000001341.


Free intraperitoneal tumor cells and outcome in gastric cancer patients: a systematic review and meta-analysis.

Pecqueux M, Fritzmann J, Adamu M, Thorlund K, Kahlert C, Reißfelder C, Weitz J, Rahbari NN.

Oncotarget. 2015 Nov 3;6(34):35564-78. doi: 10.18632/oncotarget.5595. Review.


Staged resection of bilobar colorectal liver metastases: surgical strategies.

Yang C, Rahbari NN, Mees ST, Schaab F, Koch M, Weitz J, Reissfelder C.

Langenbecks Arch Surg. 2015 Aug;400(6):633-40. doi: 10.1007/s00423-015-1310-2. Epub 2015 Jun 8. Review.


Overexpression of SIX1 is an independent prognostic marker in stage I-III colorectal cancer.

Kahlert C, Lerbs T, Pecqueux M, Herpel E, Hoffmeister M, Jansen L, Brenner H, Chang-Claude J, Bläker H, Kloor M, Roth W, Pilarsky C, Rahbari NN, Schölch S, Bork U, Reissfelder C, Weitz J, Aust D, Koch M.

Int J Cancer. 2015 Nov 1;137(9):2104-13. doi: 10.1002/ijc.29596. Epub 2015 May 21.


Circulating tumour cells and outcome in non-metastatic colorectal cancer: a prospective study.

Bork U, Rahbari NN, Schölch S, Reissfelder C, Kahlert C, Büchler MW, Weitz J, Koch M.

Br J Cancer. 2015 Apr 14;112(8):1306-13. doi: 10.1038/bjc.2015.88. Epub 2015 Mar 31.


Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis.

Weber GF, Chousterman BG, He S, Fenn AM, Nairz M, Anzai A, Brenner T, Uhle F, Iwamoto Y, Robbins CS, Noiret L, Maier SL, Zönnchen T, Rahbari NN, Schölch S, Klotzsche-von Ameln A, Chavakis T, Weitz J, Hofer S, Weigand MA, Nahrendorf M, Weissleder R, Swirski FK.

Science. 2015 Mar 13;347(6227):1260-5. doi: 10.1126/science.aaa4268.


Corrigendum. Tumor-specific cytotoxic T lymphocyte activity determines colorectal cancer patient prognosis.

Reissfelder C, Stamova S, Gossmann C, Braun M, Bonertz A, Walliczek U, Grimm M, Rahbari NN, Koch M, Saadati M, Benner A, Büchler MW, Jäger D, Halama N, Khazaie K, Weitz J, Beckhove P.

J Clin Invest. 2015 Mar 2;125(3):1364. doi: 10.1172/JCI81442. Epub 2015 Mar 2. No abstract available.


Radiotherapy combined with TLR7/8 activation induces strong immune responses against gastrointestinal tumors.

Schölch S, Rauber C, Tietz A, Rahbari NN, Bork U, Schmidt T, Kahlert C, Haberkorn U, Tomai MA, Lipson KE, Carretero R, Weitz J, Koch M, Huber PE.

Oncotarget. 2015 Mar 10;6(7):4663-76.


Influence of age on resection of colorectal liver metastases.

Schmidt T, Strowitzki MJ, Reissfelder C, Rahbari NN, Nienhueser H, Bruckner T, Rahäuser C, Keppler U, Schneider M, Büchler MW, Ulrich A.

J Surg Oncol. 2015 May;111(6):729-39. doi: 10.1002/jso.23872. Epub 2015 Jan 16.


Tumor-specific cytotoxic T lymphocyte activity determines colorectal cancer patient prognosis.

Reissfelder C, Stamova S, Gossmann C, Braun M, Bonertz A, Walliczek U, Grimm M, Rahbari NN, Koch M, Saadati M, Benner A, Büchler MW, Jäger D, Halama N, Khazaie K, Weitz J, Beckhove P.

J Clin Invest. 2015 Feb;125(2):739-51. doi: 10.1172/JCI74894. Epub 2014 Dec 22. Erratum in: J Clin Invest. 2015 Mar 2;125(3):1364.


[Lichtenstein's hernia repair].

Volk A, Rahbari NN, Koch M, Weitz J.

Zentralbl Chir. 2014 Dec;139(6):581-2. doi: 10.1055/s-0034-1383346. Epub 2014 Dec 22. German.


Prognostic relevance of minimal residual disease in colorectal cancer.

Bork U, Grützmann R, Rahbari NN, Schölch S, Distler M, Reissfelder C, Koch M, Weitz J.

World J Gastroenterol. 2014 Aug 14;20(30):10296-304. doi: 10.3748/wjg.v20.i30.10296. Review.


A systematic review of localization, surgical treatment options, and outcome of insulinoma.

Mehrabi A, Fischer L, Hafezi M, Dirlewanger A, Grenacher L, Diener MK, Fonouni H, Golriz M, Garoussi C, Fard N, Rahbari NN, Werner J, Büchler MW.

Pancreas. 2014 Jul;43(5):675-86. doi: 10.1097/MPA.0000000000000110. Review.


Comparison of various surgical approaches for extensive bilateral colorectal liver metastases.

Reissfelder C, Rahbari NN, Bejarano LU, Schmidt T, Kortes N, Kauczor HU, Büchler MW, Weitz J, Koch M.

Langenbecks Arch Surg. 2014 Apr;399(4):481-91. doi: 10.1007/s00423-014-1177-7. Epub 2014 Mar 11.


Adjuvant therapy after resection of colorectal liver metastases: the predictive value of the MSKCC clinical risk score in the era of modern chemotherapy.

Rahbari NN, Reissfelder C, Schulze-Bergkamen H, Jäger D, Büchler MW, Weitz J, Koch M.

BMC Cancer. 2014 Mar 11;14:174. doi: 10.1186/1471-2407-14-174.


Immune escape and survival mechanisms in circulating tumor cells of colorectal cancer.

Steinert G, Schölch S, Niemietz T, Iwata N, García SA, Behrens B, Voigt A, Kloor M, Benner A, Bork U, Rahbari NN, Büchler MW, Stoecklein NH, Weitz J, Koch M.

Cancer Res. 2014 Mar 15;74(6):1694-704. doi: 10.1158/0008-5472.CAN-13-1885. Epub 2014 Mar 5.


Randomized clinical trial of stapler versus clamp-crushing transection in elective liver resection.

Rahbari NN, Elbers H, Koch M, Vogler P, Striebel F, Bruckner T, Mehrabi A, Schemmer P, Büchler MW, Weitz J.

Br J Surg. 2014 Feb;101(3):200-7. doi: 10.1002/bjs.9387. Epub 2014 Jan 8.


Impact of preoperative diabetes on long-term survival after curative resection of pancreatic adenocarcinoma: a systematic review and meta-analysis.

Walter U, Kohlert T, Rahbari NN, Weitz J, Welsch T.

Ann Surg Oncol. 2014 Apr;21(4):1082-9. doi: 10.1245/s10434-013-3415-6. Epub 2013 Dec 10. Review.


Chemotherapy-associated liver injury and its influence on outcome after resection of colorectal liver metastases.

Reissfelder C, Brand K, Sobiegalla J, Rahbari NN, Bork U, Schirmacher P, Büchler MW, Weitz J, Koch M.

Surgery. 2014 Feb;155(2):245-54. doi: 10.1016/j.surg.2013.07.022. Epub 2013 Dec 5.


Neoadjuvant radiotherapy for rectal cancer: meta-analysis of randomized controlled trials.

Rahbari NN, Elbers H, Askoxylakis V, Motschall E, Bork U, Büchler MW, Weitz J, Koch M.

Ann Surg Oncol. 2013 Dec;20(13):4169-82. doi: 10.1245/s10434-013-3198-9. Epub 2013 Sep 4.


Allogeneic blood transfusion does not affect outcome after curative resection for advanced cholangiocarcinoma.

Müller SA, Mehrabi A, Rahbari NN, Warschkow R, Elbers H, Leowardi C, Fonouni H, Tarantino I, Schemmer P, Schmied BM, Büchler MW.

Ann Surg Oncol. 2014 Jan;21(1):155-64. doi: 10.1245/s10434-013-3226-9. Epub 2013 Aug 28.


Validation of the International Study Group of Rectal Cancer definition and severity grading of anastomotic leakage.

Kulu Y, Ulrich A, Bruckner T, Contin P, Welsch T, Rahbari NN, Büchler MW, Weitz J; International Study Group of Rectal Cancer.

Surgery. 2013 Jun;153(6):753-61. doi: 10.1016/j.surg.2013.02.007. Epub 2013 Apr 25.


Hyaluronic acid as a marker of sinusoidal obstruction syndrome after oxaliplatin-based chemotherapy for colorectal liver metastases: don't forget the tumor.

Rahbari NN, Weitz J.

Ann Surg Oncol. 2013 May;20(5):1405-7. doi: 10.1245/s10434-013-2916-7. No abstract available.


Circulating tumor cells and prognosis of patients with resectable colorectal liver metastases or widespread metastatic colorectal cancer: a meta-analysis.

Groot Koerkamp B, Rahbari NN, Büchler MW, Koch M, Weitz J.

Ann Surg Oncol. 2013 Jul;20(7):2156-65. doi: 10.1245/s10434-013-2907-8. Epub 2013 Mar 2. Review.


Can postoperative coffee perk up recovery time after colon surgery?

Müller SA, Rahbari NN, Schmied BM, Büchler MW.

Expert Rev Gastroenterol Hepatol. 2013 Feb;7(2):91-3. doi: 10.1586/egh.12.78. No abstract available.


Binding of the phage display derived peptide CaIX-P1 on human colorectal carcinoma cells correlates with the expression of carbonic anhydrase IX.

Askoxylakis V, Ehemann V, Rana S, Krämer S, Rahbari NN, Debus J, Haberkorn U.

Int J Mol Sci. 2012 Oct 11;13(10):13030-48. doi: 10.3390/ijms131013030.


Randomized clinical trial on the effect of coffee on postoperative ileus following elective colectomy.

Müller SA, Rahbari NN, Schneider F, Warschkow R, Simon T, von Frankenberg M, Bork U, Weitz J, Schmied BM, Büchler MW.

Br J Surg. 2012 Nov;99(11):1530-8. doi: 10.1002/bjs.8885. Epub 2012 Sep 14.


AB0 blood group and prognosis in patients with pancreatic cancer.

Rahbari NN, Bork U, Hinz U, Leo A, Kirchberg J, Koch M, Büchler MW, Weitz J.

BMC Cancer. 2012 Jul 28;12:319. doi: 10.1186/1471-2407-12-319.


Hepatitis B vs. hepatitis C infection on viral hepatitis-associated hepatocellular carcinoma.

Hiotis SP, Rahbari NN, Villanueva GA, Klegar E, Luan W, Wang Q, Yee HT.

BMC Gastroenterol. 2012 Jun 8;12:64. doi: 10.1186/1471-230X-12-64.


Bilirubin level in the drainage fluid is an early and independent predictor of clinically relevant bile leakage after hepatic resection.

Rahbari NN, Elbers H, Koch M, Kirchberg J, Dutlu M, Mehrabi A, Büchler MW, Weitz J.

Surgery. 2012 Nov;152(5):821-31. doi: 10.1016/j.surg.2012.03.012. Epub 2012 May 30.


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