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Items: 1 to 50 of 52

1.

Young Human Cholinergic Neurons Respond to Physiological Regulators and Improve Cognitive Symptoms in an Animal Model of Alzheimer's Disease.

Morelli A, Sarchielli E, Guarnieri G, Coppi E, Pantano D, Comeglio P, Nardiello P, Pugliese AM, Ballerini L, Matucci R, Ambrosini S, Castronovo G, Valente R, Mazzanti B, Bucciantini S, Maggi M, Casamenti F, Gallina P, Vannelli GB.

Front Cell Neurosci. 2017 Oct 27;11:339. doi: 10.3389/fncel.2017.00339. eCollection 2017.

2.

Dexpramipexole improves bioenergetics and outcome in experimental stroke.

Muzzi M, Gerace E, Buonvicino D, Coppi E, Resta F, Formentini L, Zecchi R, Tigli L, Guasti D, Ferri M, Camaioni E, Masi A, Pellegrini-Giampietro DE, Mannaioni G, Bani D, Pugliese AM, Chiarugi A.

Br J Pharmacol. 2018 Jan;175(2):272-283. doi: 10.1111/bph.13790. Epub 2017 May 12.

PMID:
28320070
3.

Imidazo[1,2-a]pyrazin-8-amine core for the design of new adenosine receptor antagonists: Structural exploration to target the A3 and A2A subtypes.

Poli D, Falsini M, Varano F, Betti M, Varani K, Vincenzi F, Pugliese AM, Pedata F, Dal Ben D, Thomas A, Palchetti I, Bettazzi F, Catarzi D, Colotta V.

Eur J Med Chem. 2017 Jan 5;125:611-628. doi: 10.1016/j.ejmech.2016.09.076. Epub 2016 Sep 26.

PMID:
27721147
4.

Purinergic signalling in brain ischemia.

Pedata F, Dettori I, Coppi E, Melani A, Fusco I, Corradetti R, Pugliese AM.

Neuropharmacology. 2016 May;104:105-30. doi: 10.1016/j.neuropharm.2015.11.007. Epub 2015 Nov 12. Review.

PMID:
26581499
5.

Role of adenosine in oligodendrocyte precursor maturation.

Coppi E, Cellai L, Maraula G, Dettori I, Melani A, Pugliese AM, Pedata F.

Front Cell Neurosci. 2015 Apr 24;9:155. doi: 10.3389/fncel.2015.00155. eCollection 2015. Review.

6.

The selective antagonism of P2X7 and P2Y1 receptors prevents synaptic failure and affects cell proliferation induced by oxygen and glucose deprivation in rat dentate gyrus.

Maraula G, Lana D, Coppi E, Gentile F, Mello T, Melani A, Galli A, Giovannini MG, Pedata F, Pugliese AM.

PLoS One. 2014 Dec 19;9(12):e115273. doi: 10.1371/journal.pone.0115273. eCollection 2014.

7.

The neuron-astrocyte-microglia triad in a rat model of chronic cerebral hypoperfusion: protective effect of dipyridamole.

Lana D, Melani A, Pugliese AM, Cipriani S, Nosi D, Pedata F, Giovannini MG.

Front Aging Neurosci. 2014 Nov 27;6:322. doi: 10.3389/fnagi.2014.00322. eCollection 2014.

8.

Oleuropein aglycone protects against pyroglutamylated-3 amyloid-ß toxicity: biochemical, epigenetic and functional correlates.

Luccarini I, Grossi C, Rigacci S, Coppi E, Pugliese AM, Pantano D, la Marca G, Ed Dami T, Berti A, Stefani M, Casamenti F.

Neurobiol Aging. 2015 Feb;36(2):648-63. doi: 10.1016/j.neurobiolaging.2014.08.029. Epub 2014 Sep 6.

PMID:
25293421
9.

Adenosine receptors in cerebral ischemia.

Melani A, Pugliese AM, Pedata F.

Int Rev Neurobiol. 2014;119:309-48. doi: 10.1016/B978-0-12-801022-8.00013-1. Review.

PMID:
25175971
10.

Adenosine A2A receptors modulate acute injury and neuroinflammation in brain ischemia.

Pedata F, Pugliese AM, Coppi E, Dettori I, Maraula G, Cellai L, Melani A.

Mediators Inflamm. 2014;2014:805198. doi: 10.1155/2014/805198. Epub 2014 Aug 5. Review.

11.

Ear acupuncture and fMRI: a pilot study for assessing the specificity of auricular points.

Romoli M, Allais G, Airola G, Benedetto C, Mana O, Giacobbe M, Pugliese AM, Battistella G, Fornari E.

Neurol Sci. 2014 May;35 Suppl 1:189-93. doi: 10.1007/s10072-014-1768-7.

PMID:
24867864
12.

Hippocampal long term memory: effect of the cholinergic system on local protein synthesis.

Lana D, Cerbai F, Di Russo J, Boscaro F, Giannetti A, Petkova-Kirova P, Pugliese AM, Giovannini MG.

Neurobiol Learn Mem. 2013 Nov;106:246-57. doi: 10.1016/j.nlm.2013.09.013. Epub 2013 Sep 27.

PMID:
24076274
13.

Anticonvulsant effect of AMP by direct activation of adenosine A1 receptor.

Muzzi M, Coppi E, Pugliese AM, Chiarugi A.

Exp Neurol. 2013 Dec;250:189-93. doi: 10.1016/j.expneurol.2013.09.010. Epub 2013 Sep 19.

PMID:
24056265
14.

Adenosine A₂A receptors inhibit delayed rectifier potassium currents and cell differentiation in primary purified oligodendrocyte cultures.

Coppi E, Cellai L, Maraula G, Pugliese AM, Pedata F.

Neuropharmacology. 2013 Oct;73:301-10. doi: 10.1016/j.neuropharm.2013.05.035. Epub 2013 Jun 13.

PMID:
23770463
15.

UDP-glucose enhances outward K(+) currents necessary for cell differentiation and stimulates cell migration by activating the GPR17 receptor in oligodendrocyte precursors.

Coppi E, Maraula G, Fumagalli M, Failli P, Cellai L, Bonfanti E, Mazzoni L, Coppini R, Abbracchio MP, Pedata F, Pugliese AM.

Glia. 2013 Jul;61(7):1155-71. doi: 10.1002/glia.22506. Epub 2013 May 2.

PMID:
23640798
16.

Amyloid-β oligomer synaptotoxicity is mimicked by oligomers of the model protein HypF-N.

Tatini F, Pugliese AM, Traini C, Niccoli S, Maraula G, Ed Dami T, Mannini B, Scartabelli T, Pedata F, Casamenti F, Chiti F.

Neurobiol Aging. 2013 Sep;34(9):2100-9. doi: 10.1016/j.neurobiolaging.2013.03.020. Epub 2013 Apr 18.

PMID:
23601807
17.

Effects of oxygen and glucose deprivation on synaptic transmission in rat dentate gyrus: role of A2A adenosine receptors.

Maraula G, Traini C, Mello T, Coppi E, Galli A, Pedata F, Pugliese AM.

Neuropharmacology. 2013 Apr;67:511-20. doi: 10.1016/j.neuropharm.2012.12.002. Epub 2012 Dec 19.

PMID:
23261865
18.

Neurological basis of AMP-dependent thermoregulation and its relevance to central and peripheral hyperthermia.

Muzzi M, Blasi F, Masi A, Coppi E, Traini C, Felici R, Pittelli M, Cavone L, Pugliese AM, Moroni F, Chiarugi A.

J Cereb Blood Flow Metab. 2013 Feb;33(2):183-90. doi: 10.1038/jcbfm.2012.157. Epub 2012 Oct 24.

19.

3-Hydroxy-1H-quinazoline-2,4-dione derivatives as new antagonists at ionotropic glutamate receptors: molecular modeling and pharmacological studies.

Colotta V, Lenzi O, Catarzi D, Varano F, Squarcialupi L, Costagli C, Galli A, Ghelardini C, Pugliese AM, Maraula G, Coppi E, Pellegrini-Giampietro DE, Pedata F, Sabbadin D, Moro S.

Eur J Med Chem. 2012 Aug;54:470-82. doi: 10.1016/j.ejmech.2012.05.036. Epub 2012 Jun 4.

PMID:
22704999
20.

[Severe hypercholesterolemia in children. Presentation of two cases and update of the literature].

Araujo MB, Pacce MS, Bravo M, Pugliese AM, Mazza C.

Arch Argent Pediatr. 2011 Aug;109(4):e67-71. doi: 10.1590/S0325-00752011000400015. Review. Spanish.

21.

P2 receptor antagonists prevent synaptic failure and extracellular signal-regulated kinase 1/2 activation induced by oxygen and glucose deprivation in rat CA1 hippocampus in vitro.

Traini C, Pedata F, Cipriani S, Mello T, Galli A, Giovannini MG, Cerbai F, Volpini R, Cristalli G, Pugliese AM.

Eur J Neurosci. 2011 Jun;33(12):2203-15. doi: 10.1111/j.1460-9568.2011.07667.x. Epub 2011 Apr 1.

PMID:
21453436
22.

Functional characterization of two isoforms of the P2Y-like receptor GPR17: [35S]GTPgammaS binding and electrophysiological studies in 1321N1 cells.

Pugliese AM, Trincavelli ML, Lecca D, Coppi E, Fumagalli M, Ferrario S, Failli P, Daniele S, Martini C, Pedata F, Abbracchio MP.

Am J Physiol Cell Physiol. 2009 Oct;297(4):C1028-40. doi: 10.1152/ajpcell.00658.2008. Epub 2009 Jul 22.

23.

The adenosine A2A receptor antagonist ZM241385 enhances neuronal survival after oxygen-glucose deprivation in rat CA1 hippocampal slices.

Pugliese AM, Traini C, Cipriani S, Gianfriddo M, Mello T, Giovannini MG, Galli A, Pedata F.

Br J Pharmacol. 2009 Jul;157(5):818-30. doi: 10.1111/j.1476-5381.2009.00218.x. Epub 2009 May 5.

24.

Pyrido[2,3-e]-1,2,4-triazolo[4,3-a]pyrazin-1-one as a new scaffold to develop potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies.

Colotta V, Lenzi O, Catarzi D, Varano F, Filacchioni G, Martini C, Trincavelli L, Ciampi O, Pugliese AM, Traini C, Pedata F, Morizzo E, Moro S.

J Med Chem. 2009 Apr 23;52(8):2407-19. doi: 10.1021/jm8014876.

PMID:
19301821
25.

Synthesis, ligand-receptor modeling studies and pharmacological evaluation of novel 4-modified-2-aryl-1,2,4-triazolo[4,3-a]quinoxalin-1-one derivatives as potent and selective human A3 adenosine receptor antagonists.

Colotta V, Catarzi D, Varano F, Lenzi O, Filacchioni G, Martini C, Trincavelli L, Ciampi O, Traini C, Pugliese AM, Pedata F, Morizzo E, Moro S.

Bioorg Med Chem. 2008 Jun 1;16(11):6086-102. doi: 10.1016/j.bmc.2008.04.039. Epub 2008 Apr 24.

PMID:
18468446
26.

The role of ATP and adenosine in the brain under normoxic and ischemic conditions.

Pedata F, Melani A, Pugliese AM, Coppi E, Cipriani S, Traini C.

Purinergic Signal. 2007 Sep;3(4):299-310. doi: 10.1007/s11302-007-9085-8. Epub 2007 Oct 11.

27.

Role of P2 purinergic receptors in synaptic transmission under normoxic and ischaemic conditions in the CA1 region of rat hippocampal slices.

Coppi E, Pugliese AM, Stephan H, Müller CE, Pedata F.

Purinergic Signal. 2007 Jun;3(3):203-19. doi: 10.1007/s11302-006-9049-4. Epub 2007 Jan 3.

28.

New 2-arylpyrazolo[3,4-c]quinoline derivatives as potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies.

Colotta V, Catarzi D, Varano F, Capelli F, Lenzi O, Filacchioni G, Martini C, Trincavelli L, Ciampi O, Pugliese AM, Pedata F, Schiesaro A, Morizzo E, Moro S.

J Med Chem. 2007 Aug 23;50(17):4061-74. Epub 2007 Aug 1.

PMID:
17665891
29.

Role of adenosine A3 receptors on CA1 hippocampal neurotransmission during oxygen-glucose deprivation episodes of different duration.

Pugliese AM, Coppi E, Volpini R, Cristalli G, Corradetti R, Jeong LS, Jacobson KA, Pedata F.

Biochem Pharmacol. 2007 Sep 1;74(5):768-79. Epub 2007 Jun 7.

30.

ATP modulates cell proliferation and elicits two different electrophysiological responses in human mesenchymal stem cells.

Coppi E, Pugliese AM, Urbani S, Melani A, Cerbai E, Mazzanti B, Bosi A, Saccardi R, Pedata F.

Stem Cells. 2007 Jul;25(7):1840-9. Epub 2007 Apr 19.

31.

Neuronal control of the cardiac responses to osmotic stress in the gastropod limpet Patella caerulea.

Bini G, Pugliese AM, Pepeu G, Chelazzi G.

J Exp Zool A Comp Exp Biol. 2006 Jun 1;305(6):472-9.

PMID:
16646089
32.
33.

Tetrodotoxin prevents copper-induced bradycardia in gastropod limpets.

Bini G, Pugliese AM, Pepeu G, Chelazzi G.

Environ Pollut. 2006 Jan;139(1):79-85. Epub 2005 Jul 1.

PMID:
15993526
34.
35.

A2A receptors in neuroprotection of dopaminergic neurons.

Pedata F, Pugliese AM, Melani A, Gianfriddo M.

Neurology. 2003 Dec 9;61(11 Suppl 6):S49-50. No abstract available.

PMID:
14663010
36.

AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram).

Galeotti N, Ghelardini C, Pittaluga A, Pugliese AM, Bartolini A, Manetti D, Romanelli MN, Gualtieri F.

Naunyn Schmiedebergs Arch Pharmacol. 2003 Dec;368(6):538-45. Epub 2003 Nov 5.

PMID:
14600801
37.
39.

Local anaesthetic, antibacterial and antifungal properties of sesquiterpenes from myrrh.

Dolara P, Corte B, Ghelardini C, Pugliese AM, Cerbai E, Menichetti S, Lo Nostro A.

Planta Med. 2000 May;66(4):356-8.

PMID:
10865454
40.

Electrophysiological studies on oxindole, a neurodepressant tryptophan metabolite.

Mannaioni G, Carpenedo R, Pugliese AM, Corradetti R, Moroni F.

Br J Pharmacol. 1998 Dec;125(8):1751-60.

41.

Electrophysiological effects of felbamate.

Corradetti R, Pugliese AM.

Life Sci. 1998;63(13):1075-88. Review.

PMID:
9763203
43.

Felbamate decreases synaptic transmission in the CA1 region of rat hippocampal slices.

Pugliese AM, Passani MB, Pepeu G, Corradetti R.

J Pharmacol Exp Ther. 1996 Dec;279(3):1100-8.

PMID:
8968330
44.
45.

Electrophysiological effects of WAY 100635, a new 5-HT1A receptor antagonist, on dorsal raphe nucleus serotoninergic neurones and CA1 pyramidal cells in vitro.

Corradetti R, Pugliese AM, Le Poul E, Laaris N, Hamon M, Lanfumey L.

Acta Physiol Hung. 1996;84(4):407-9.

PMID:
9328615
46.

EPSP-spike potentiation during primed burst-induced long-term potentiation in the CA1 region of rat hippocampal slices.

Pugliese AM, Ballerini L, Passani MB, Corradetti R.

Neuroscience. 1994 Oct;62(4):1021-32.

PMID:
7845583
47.

Effects of DAU 6215, a novel 5-hydroxytryptamine3 (5-HT3) antagonist on electrophysiological properties of the rat hippocampus.

Passani MB, Pugliese AM, Azzurrini M, Corradetti R.

Br J Pharmacol. 1994 Jun;112(2):695-703.

48.

Electrophysiological interactions between 5-hydroxytryptamine and thyrotropin releasing hormone on rat hippocampal CA1 neurons.

Ballerini L, Corradetti R, Nistri A, Pugliese AM, Stocca G.

Eur J Neurosci. 1994 Jun 1;6(6):953-60.

PMID:
7952282
49.

Investigations into the adenosine outflow from hippocampal slices evoked by ischemia-like conditions.

Pedata F, Latini S, Pugliese AM, Pepeu G.

J Neurochem. 1993 Jul;61(1):284-9.

PMID:
8515275
50.

Serotonin blocks the long-term potentiation induced by primed burst stimulation in the CA1 region of rat hippocampal slices.

Corradetti R, Ballerini L, Pugliese AM, Pepeu G.

Neuroscience. 1992;46(3):511-8.

PMID:
1545909

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