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Items: 8


Intracellular immunization against HIV infection with an intracellular antibody that mimics HIV integrase binding to the cellular LEDGF protein.

Bao L, Hannon C, Cruz-Mignoni A, Ptchelkine D, Sun MY, Miller A, Bunjobpol W, Quevedo CE, Derveni M, Chambers J, Simmons A, Phillips SEV, Rabbitts TH.

Sci Rep. 2017 Dec 4;7(1):16869. doi: 10.1038/s41598-017-16742-2.


Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging.

Ptchelkine D, Gillum A, Mochizuki T, Lucas-Staat S, Liu Y, Krupovic M, Phillips SEV, Prangishvili D, Huiskonen JT.

Nat Commun. 2017 Nov 10;8(1):1436. doi: 10.1038/s41467-017-01668-0.


RPA activates the XPF-ERCC1 endonuclease to initiate processing of DNA interstrand crosslinks.

Abdullah UB, McGouran JF, Brolih S, Ptchelkine D, El-Sagheer AH, Brown T, McHugh PJ.

EMBO J. 2017 Jul 14;36(14):2047-2060. doi: 10.15252/embj.201796664. Epub 2017 Jun 12.


5-Formylcytosine does not change the global structure of DNA.

Hardwick JS, Ptchelkine D, El-Sagheer AH, Tear I, Singleton D, Phillips SEV, Lane AN, Brown T.

Nat Struct Mol Biol. 2017 Jun;24(6):544-552. doi: 10.1038/nsmb.3411. Epub 2017 May 15.


Structural framework for covalent inhibition of Clostridium botulinum neurotoxin A by targeting Cys165.

Stura EA, Le Roux L, Guitot K, Garcia S, Bregant S, Beau F, Vera L, Collet G, Ptchelkine D, Bakirci H, Dive V.

J Biol Chem. 2012 Sep 28;287(40):33607-14. Epub 2012 Aug 6.


Mass spectrometry reveals stable modules in holo and apo RNA polymerases I and III.

Lane LA, Fernández-Tornero C, Zhou M, Morgner N, Ptchelkine D, Steuerwald U, Politis A, Lindner D, Gvozdenovic J, Gavin AC, Müller CW, Robinson CV.

Structure. 2011 Jan 12;19(1):90-100. doi: 10.1016/j.str.2010.11.009.


Structural basis of TBX5-DNA recognition: the T-box domain in its DNA-bound and -unbound form.

Stirnimann CU, Ptchelkine D, Grimm C, Müller CW.

J Mol Biol. 2010 Jul 2;400(1):71-81. doi: 10.1016/j.jmb.2010.04.052. Epub 2010 May 5.


Structural basis for LEAFY floral switch function and similarity with helix-turn-helix proteins.

Hamès C, Ptchelkine D, Grimm C, Thevenon E, Moyroud E, Gérard F, Martiel JL, Benlloch R, Parcy F, Müller CW.

EMBO J. 2008 Oct 8;27(19):2628-37. doi: 10.1038/emboj.2008.184. Epub 2008 Sep 11.

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