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Items: 1 to 50 of 242

1.

Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand.

McWilliams TG, Prescott AR, Montava-Garriga L, Ball G, Singh F, Barini E, Muqit MMK, Brooks SP, Ganley IG.

Cell Metab. 2018 Feb 6;27(2):439-449.e5. doi: 10.1016/j.cmet.2017.12.008. Epub 2018 Jan 11.

2.

Radiotherapy of MRI-detected involved internal mammary lymph nodes in breast cancer.

Sachdev S, Goodman CR, Neuschler E, Kalakota K, Cutright D, Donnelly ED, Hayes JP, Prescott AE, Mirabelli G, Strauss JB.

Radiat Oncol. 2017 Dec 19;12(1):199. doi: 10.1186/s13014-017-0934-5.

3.

Rab-GTPase binding effector protein 2 (RABEP2) is a primed substrate for Glycogen Synthase kinase-3 (GSK3).

Logie L, Van Aalten L, Knebel A, Force T, Hastie CJ, MacLauchlan H, Campbell DG, Gourlay R, Prescott A, Davidson J, Fuller W, Sutherland C.

Sci Rep. 2017 Dec 15;7(1):17682. doi: 10.1038/s41598-017-17087-6.

4.

PAWS1 controls cytoskeletal dynamics and cell migration through association with the SH3 adaptor CD2AP.

Cummins TD, Wu KZL, Bozatzi P, Dingwell KS, Macartney TJ, Wood NT, Varghese J, Gourlay R, Campbell DG, Prescott A, Griffis E, Smith JC, Sapkota GP.

J Cell Sci. 2018 Jan 10;131(1). pii: jcs202390. doi: 10.1242/jcs.202390.

5.

Mechanism of activation of SGK3 by growth factors via the Class 1 and Class 3 PI3Ks.

Malik N, Macartney T, Hornberger A, Anderson KE, Tovell H, Prescott AR, Alessi DR.

Biochem J. 2018 Jan 2;475(1):117-135. doi: 10.1042/BCJ20170650.

6.

The role of a palliative care intervention in moderating the relationship between depression and survival among individuals with advanced cancer.

Prescott AT, Hull JG, Dionne-Odom JN, Tosteson TD, Lyons KD, Li Z, Li Z, Dragnev KH, Hegel MT, Steinhauser KE, Ahles TA, Bakitas MA.

Health Psychol. 2017 Dec;36(12):1140-1146. doi: 10.1037/hea0000544. Epub 2017 Oct 19.

PMID:
29048177
7.

Bifunctionality of a biofilm matrix protein controlled by redox state.

Arnaouteli S, Ferreira AS, Schor M, Morris RJ, Bromley KM, Jo J, Cortez KL, Sukhodub T, Prescott AR, Dietrich LEP, MacPhee CE, Stanley-Wall NR.

Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):E6184-E6191. doi: 10.1073/pnas.1707687114. Epub 2017 Jul 11.

8.

Brd4-Brd2 isoform switching coordinates pluripotent exit and Smad2-dependent lineage specification.

Fernandez-Alonso R, Davidson L, Hukelmann J, Zengerle M, Prescott AR, Lamond A, Ciulli A, Sapkota GP, Findlay GM.

EMBO Rep. 2017 Jul;18(7):1108-1122. doi: 10.15252/embr.201643534. Epub 2017 Jun 6.

9.

Total ankle arthroplasty versus ankle arthrodesis-a comparison of outcomes over the last decade.

Lawton CD, Butler BA, Dekker RG 2nd, Prescott A, Kadakia AR.

J Orthop Surg Res. 2017 May 18;12(1):76. doi: 10.1186/s13018-017-0576-1. Review.

10.

Esophagectomy for cancer in octogenarians: should we do it?

Paulus E, Ripat C, Koshenkov V, Prescott AT, Sethi K, Stuart H, Tiesi G, Livingstone AS, Yakoub D.

Langenbecks Arch Surg. 2017 May;402(3):539-545. doi: 10.1007/s00423-017-1573-x. Epub 2017 Mar 16.

PMID:
28303419
11.

Combining in silico evolution and nonlinear dimensionality reduction to redesign responses of signaling networks.

Prescott AM, Abel SM.

Phys Biol. 2017 Jan 13;13(6):066015. doi: 10.1088/1478-3975/13/6/066015.

PMID:
28085678
12.

Analysis of Network Topologies Underlying Ethylene Growth Response Kinetics.

Prescott AM, McCollough FW, Eldreth BL, Binder BM, Abel SM.

Front Plant Sci. 2016 Aug 30;7:1308. doi: 10.3389/fpls.2016.01308. eCollection 2016.

13.

mito-QC illuminates mitophagy and mitochondrial architecture in vivo.

McWilliams TG, Prescott AR, Allen GF, Tamjar J, Munson MJ, Thomson C, Muqit MM, Ganley IG.

J Cell Biol. 2016 Aug 1;214(3):333-45. doi: 10.1083/jcb.201603039. Epub 2016 Jul 25.

14.

Deep Intronic Sequence Variants in COL2A1 Affect the Alternative Splicing Efficiency of Exon 2, and May Confer a Risk for Rhegmatogenous Retinal Detachment.

Spickett C, Hysi P, Hammond CJ, Prescott A, Fincham GS, Poulson AV, McNinch AM, Richards AJ, Snead MP.

Hum Mutat. 2016 Oct;37(10):1085-96. doi: 10.1002/humu.23050. Epub 2016 Aug 21.

PMID:
27406592
15.

The effect of pelvic radiotherapy on vaginal brachytherapy cylinder diameter: Implications for optimal treatment order.

Rakhra SS, Weaver C, Donnelly ED, Helenowski I, Prescott AE, Strauss JB.

Brachytherapy. 2016 Sep-Oct;15(5):549-53. doi: 10.1016/j.brachy.2016.04.391. Epub 2016 Jun 14.

PMID:
27317190
16.

Family Caregiver Depressive Symptom and Grief Outcomes From the ENABLE III Randomized Controlled Trial.

Dionne-Odom JN, Azuero A, Lyons KD, Hull JG, Prescott AT, Tosteson T, Frost J, Dragnev KH, Bakitas MA.

J Pain Symptom Manage. 2016 Sep;52(3):378-85. doi: 10.1016/j.jpainsymman.2016.03.014. Epub 2016 Jun 3.

17.

The E3 ubiquitin ligase ZNRF2 is a substrate of mTORC1 and regulates its activation by amino acids.

Hoxhaj G, Caddye E, Najafov A, Houde VP, Johnson C, Dissanayake K, Toth R, Campbell DG, Prescott AR, MacKintosh C.

Elife. 2016 Apr 22;5. pii: e12278. doi: 10.7554/eLife.12278.

18.

Associations between advanced cancer patients' survival and family caregiver presence and burden.

Dionne-Odom JN, Hull JG, Martin MY, Lyons KD, Prescott AT, Tosteson T, Li Z, Akyar I, Raju D, Bakitas MA.

Cancer Med. 2016 May;5(5):853-62. doi: 10.1002/cam4.653. Epub 2016 Feb 10.

19.

The PDK1-Rsk Signaling Pathway Controls Langerhans Cell Proliferation and Patterning.

Zaru R, Matthews SP, Edgar AJ, Prescott AR, Gomez-Nicola D, Hanauer A, Watts C.

J Immunol. 2015 Nov 1;195(9):4264-72. doi: 10.4049/jimmunol.1501520. Epub 2015 Sep 23.

20.

GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling.

Stretton C, Hoffmann TM, Munson MJ, Prescott A, Taylor PM, Ganley IG, Hundal HS.

Biochem J. 2015 Sep 1;470(2):207-21. doi: 10.1042/BJ20150404. Epub 2015 Jul 9.

21.

A cost-effective technique for cardiac sparing with deep inspiration-breath hold (DIBH).

Macrie BD, Donnelly ED, Hayes JP, Gopalakrishnan M, Philip RT, Reczek J, Prescott A, Strauss JB.

Phys Med. 2015 Nov;31(7):733-7. doi: 10.1016/j.ejmp.2015.06.006. Epub 2015 Jun 24.

PMID:
26117242
22.

Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation.

Kazlauskaite A, Martínez-Torres RJ, Wilkie S, Kumar A, Peltier J, Gonzalez A, Johnson C, Zhang J, Hope AG, Peggie M, Trost M, van Aalten DM, Alessi DR, Prescott AR, Knebel A, Walden H, Muqit MM.

EMBO Rep. 2015 Aug;16(8):939-54. doi: 10.15252/embr.201540352. Epub 2015 Jun 25.

23.

A key role for PTP1B in dendritic cell maturation, migration, and T cell activation.

Martin-Granados C, Prescott AR, Le Sommer S, Klaska IP, Yu T, Muckersie E, Giuraniuc CV, Grant L, Delibegovic M, Forrester JV.

J Mol Cell Biol. 2015 Dec;7(6):517-28. doi: 10.1093/jmcb/mjv032. Epub 2015 Jun 10.

PMID:
26063615
24.

Suppression of interferon β gene transcription by inhibitors of bromodomain and extra-terminal (BET) family members.

Malik N, Vollmer S, Nanda SK, Lopez-Pelaez M, Prescott A, Gray N, Cohen P.

Biochem J. 2015 Jun 15;468(3):363-72. doi: 10.1042/BJ20141523. Epub 2015 Apr 20.

25.

Selection and molecular characterization of cellulolytic-xylanolytic fungi from surface soil-biomass mixtures from Black Belt sites.

Okeke BC, Hall RW, Nanjundaswamy A, Thomson MS, Deravi Y, Sawyer L, Prescott A.

Microbiol Res. 2015 Jun;175:24-33. doi: 10.1016/j.micres.2015.03.001. Epub 2015 Mar 10.

26.

High-resolution quantitative proteome analysis reveals substantial differences between phagosomes of RAW 264.7 and bone marrow derived macrophages.

Guo M, Härtlova A, Dill BD, Prescott AR, Gierliński M, Trost M.

Proteomics. 2015 Sep;15(18):3169-74. doi: 10.1002/pmic.201400431. Epub 2015 Feb 5.

27.

RAB1A promotes Vaccinia virus replication by facilitating the production of intracellular enveloped virions.

Pechenick Jowers T, Featherstone RJ, Reynolds DK, Brown HK, James J, Prescott A, Haga IR, Beard PM.

Virology. 2015 Jan 15;475:66-73. doi: 10.1016/j.virol.2014.11.007. Epub 2014 Nov 26.

28.
29.

Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase.

Bago R, Malik N, Munson MJ, Prescott AR, Davies P, Sommer E, Shpiro N, Ward R, Cross D, Ganley IG, Alessi DR.

Biochem J. 2014 Nov 1;463(3):413-27. doi: 10.1042/BJ20140889.

30.

A longitudinal study of risk-glorifying video games and behavioral deviance.

Hull JG, Brunelle TJ, Prescott AT, Sargent JD.

J Pers Soc Psychol. 2014 Aug;107(2):300-25. doi: 10.1037/a0036058.

31.

A crucial role for β2 integrins in podosome formation, dynamics and Toll-like-receptor-signaled disassembly in dendritic cells.

Gawden-Bone C, West MA, Morrison VL, Edgar AJ, McMillan SJ, Dill BD, Trost M, Prescott A, Fagerholm SC, Watts C.

J Cell Sci. 2014 Oct 1;127(Pt 19):4213-24. doi: 10.1242/jcs.151167. Epub 2014 Aug 1.

32.

High-confidence glycosome proteome for procyclic form Trypanosoma brucei by epitope-tag organelle enrichment and SILAC proteomics.

Güther ML, Urbaniak MD, Tavendale A, Prescott A, Ferguson MA.

J Proteome Res. 2014 Jun 6;13(6):2796-806. doi: 10.1021/pr401209w. Epub 2014 May 13.

33.

Interplay between Polo kinase, LKB1-activated NUAK1 kinase, PP1βMYPT1 phosphatase complex and the SCFβTrCP E3 ubiquitin ligase.

Banerjee S, Zagórska A, Deak M, Campbell DG, Prescott AR, Alessi DR.

Biochem J. 2014 Jul 15;461(2):233-45. doi: 10.1042/BJ20140408.

34.

Biochemical analysis of TssK, a core component of the bacterial Type VI secretion system, reveals distinct oligomeric states of TssK and identifies a TssK-TssFG subcomplex.

English G, Byron O, Cianfanelli FR, Prescott AR, Coulthurst SJ.

Biochem J. 2014 Jul 15;461(2):291-304. doi: 10.1042/BJ20131426.

35.

Time-resolved quantitative proteomics implicates the core snRNP protein SmB together with SMN in neural trafficking.

Prescott AR, Bales A, James J, Trinkle-Mulcahy L, Sleeman JE.

J Cell Sci. 2014 Feb 15;127(Pt 4):812-27. doi: 10.1242/jcs.137703. Epub 2013 Dec 19.

36.
37.

Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases.

Banerjee S, Buhrlage SJ, Huang HT, Deng X, Zhou W, Wang J, Traynor R, Prescott AR, Alessi DR, Gray NS.

Biochem J. 2014 Jan 1;457(1):215-25. doi: 10.1042/BJ20131152.

38.

p53 and cell cycle independent dysregulation of autophagy in chronic lymphocytic leukaemia.

Groves MJ, Johnson CE, James J, Prescott AR, Cunningham J, Haydock S, Pepper C, Fegan C, Pirrie L, Westwood NJ, Coates PJ, Ganley IG, Tauro S.

Br J Cancer. 2013 Oct 29;109(9):2434-44. doi: 10.1038/bjc.2013.601. Epub 2013 Oct 3.

39.

Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects.

Saunders SP, Goh CS, Brown SJ, Palmer CN, Porter RM, Cole C, Campbell LE, Gierlinski M, Barton GJ, Schneider G, Balmain A, Prescott AR, Weidinger S, Baurecht H, Kabesch M, Gieger C, Lee YA, Tavendale R, Mukhopadhyay S, Turner SW, Madhok VB, Sullivan FM, Relton C, Burn J, Meggitt S, Smith CH, Allen MA, Barker JN, Reynolds NJ, Cordell HJ, Irvine AD, McLean WH, Sandilands A, Fallon PG.

J Allergy Clin Immunol. 2013 Nov;132(5):1121-9. doi: 10.1016/j.jaci.2013.08.046. Epub 2013 Sep 29.

40.

A synthetic system for expression of components of a bacterial microcompartment.

Sargent F, Davidson FA, Kelly CL, Binny R, Christodoulides N, Gibson D, Johansson E, Kozyrska K, Lado LL, Maccallum J, Montague R, Ortmann B, Owen R, Coulthurst SJ, Dupuy L, Prescott AR, Palmer T.

Microbiology. 2013 Nov;159(Pt 11):2427-36. doi: 10.1099/mic.0.069922-0. Epub 2013 Sep 6.

41.

Rare complication after viral illness.

Allan BJ, Prescott AT, Greene JA, Campuzano-Zuluaga G, Marttos A.

JAMA Surg. 2013 Oct;148(10):983-4. doi: 10.1001/jamasurg.2013.313. No abstract available.

PMID:
23986336
42.

Protein phosphatase 4 is phosphorylated and inactivated by Cdk in response to spindle toxins and interacts with γ-tubulin.

Voss M, Campbell K, Saranzewa N, Campbell DG, Hastie CJ, Peggie MW, Martin-Granados C, Prescott AR, Cohen PT.

Cell Cycle. 2013 Sep 1;12(17):2876-87. doi: 10.4161/cc.25919. Epub 2013 Aug 2.

43.

BslA is a self-assembling bacterial hydrophobin that coats the Bacillus subtilis biofilm.

Hobley L, Ostrowski A, Rao FV, Bromley KM, Porter M, Prescott AR, MacPhee CE, van Aalten DM, Stanley-Wall NR.

Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13600-5. doi: 10.1073/pnas.1306390110. Epub 2013 Jul 31. Erratum in: Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):E5371-5.

44.

DEAF1 is a Pellino1-interacting protein required for interferon production by Sendai virus and double-stranded RNA.

Ordureau A, Enesa K, Nanda S, Le Francois B, Peggie M, Prescott A, Albert PR, Cohen P.

J Biol Chem. 2013 Aug 23;288(34):24569-80. doi: 10.1074/jbc.M113.479550. Epub 2013 Jul 11.

45.

The β2 integrin-kindlin-3 interaction is essential for T-cell homing but dispensable for T-cell activation in vivo.

Morrison VL, MacPherson M, Savinko T, Lek HS, Prescott A, Fagerholm SC.

Blood. 2013 Aug 22;122(8):1428-36. doi: 10.1182/blood-2013-02-484998. Epub 2013 Jul 3.

46.

Prefrontal mechanisms of behavioral flexibility, emotion regulation and value updating.

Rudebeck PH, Saunders RC, Prescott AT, Chau LS, Murray EA.

Nat Neurosci. 2013 Aug;16(8):1140-5. doi: 10.1038/nn.3440. Epub 2013 Jun 23.

47.

The spontaneously adhesive leukocyte function-associated antigen-1 (LFA-1) integrin in effector T cells mediates rapid actin- and calmodulin-dependent adhesion strengthening to ligand under shear flow.

Lek HS, Morrison VL, Conneely M, Campbell PA, McGloin D, Kliche S, Watts C, Prescott A, Fagerholm SC.

J Biol Chem. 2013 May 24;288(21):14698-708. doi: 10.1074/jbc.M112.430918. Epub 2013 Apr 12.

48.

The specificity of the interaction between αB-crystallin and desmin filaments and its impact on filament aggregation and cell viability.

Elliott JL, Der Perng M, Prescott AR, Jansen KA, Koenderink GH, Quinlan RA.

Philos Trans R Soc Lond B Biol Sci. 2013 Mar 25;368(1617):20120375. doi: 10.1098/rstb.2012.0375. Print 2013 May 5.

49.

Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6.

MacCallum SF, Groves MJ, James J, Murray K, Appleyard V, Prescott AR, Drbal AA, Nicolaou A, Cunningham J, Haydock S, Ganley IG, Westwood NJ, Coates PJ, Lain S, Tauro S.

Sci Rep. 2013;3:1275. doi: 10.1038/srep01275.

50.

Developing and pilot testing practical measures of preanalytic surgical specimen identification defects.

Bixenstine PJ, Zarbo RJ, Holzmueller CG, Yenokyan G, Robinson R, Hudson DW, Prescott AM, Hubble R, Murphy MM, George CT, D'Angelo R, Watson SR, Lubomski LH, Berenholtz SM.

Am J Med Qual. 2013 Jul-Aug;28(4):308-14. doi: 10.1177/1062860612469824. Epub 2013 Jan 15.

PMID:
23322909

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