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Items: 1 to 50 of 75

1.

Analysis of Immunogenicity of Intracellular CTAR Fragments of Epstein-Barr Virus Latent Phase Protein LMP1.

Lomakin YA, Shmidt AA, Bobik TV, Chernov AS, Pyrkov AY, Aleksandrova NM, Okunola DO, Vaskina MI, Ponomarenko NA, Telegin GB, Dubina MV, Belogurov AA Jr.

Bull Exp Biol Med. 2017 Oct;163(6):766-771. doi: 10.1007/s10517-017-3899-3. Epub 2017 Oct 24.

PMID:
29063322
2.

Evolution of catalytic centers of antibodies by virtual screening of broad repertoire of mutants using supercomputer.

Golovin AV, Smirnov IV, Stepanova AV, Zalevskiy AO, Zlobin AS, Ponomarenko NA, Belogurov AA, Knorre VD, Hurs EN, Chatziefthimiou SD, Wilmanns M, Blackburn GM, Khomutov RM, Gabibov AG.

Dokl Biochem Biophys. 2017 Jul;475(1):245-249. doi: 10.1134/S1607672917040019. Epub 2017 Sep 2.

PMID:
28864894
3.

Genetic Engineering of Native Chain Combinations of B-Cell Repertoires on the Surface of Methylotrophic Yeasts Pichia pastoris.

Bobik TV, Shurdova EM, Smirnov IV, Ponomarenko NA, Khurs EN, Knorre VD, Gabibov AG.

Bull Exp Biol Med. 2017 Jun;163(2):263-267. doi: 10.1007/s10517-017-3780-4. Epub 2017 Jul 18.

PMID:
28726211
4.

Preparation of Recombinant Serpin from Red King Crab Paralithodes сamtschaticus for Biomedical Research Purposes.

Kostin NN, Ponomarenko NA, Isaev VA, Rudenskaya GN, Bobik TV, Gabibov AG, Smirnov IV.

Bull Exp Biol Med. 2017 Jun;163(2):210-213. doi: 10.1007/s10517-017-3768-0. Epub 2017 Jul 18.

PMID:
28726206
5.

Design of Chemical Conjugate for Targeted Therapy of Multiple Sclerosis Based of Constant Fragment of Human Antibody Heavy Chain and Peptoid Analog of Autoantigen MOG35-55.

Lomakin YA, Stepanov AV, Balabashin DS, Ponomarenko NA, Smirnov IV, Belogurov AA Jr.

Bull Exp Biol Med. 2017 Apr;162(6):777-780. doi: 10.1007/s10517-017-3711-4. Epub 2017 Apr 21.

PMID:
28429225
6.

Microfluidic droplet platform for ultrahigh-throughput single-cell screening of biodiversity.

Terekhov SS, Smirnov IV, Stepanova AV, Bobik TV, Mokrushina YA, Ponomarenko NA, Belogurov AA Jr, Rubtsova MP, Kartseva OV, Gomzikova MO, Moskovtsev AA, Bukatin AS, Dubina MV, Kostryukova ES, Babenko VV, Vakhitova MT, Manolov AI, Malakhova MV, Kornienko MA, Tyakht AV, Vanyushkina AA, Ilina EN, Masson P, Gabibov AG, Altman S.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2550-2555. doi: 10.1073/pnas.1621226114. Epub 2017 Feb 15.

7.

Robotic QM/MM-driven maturation of antibody combining sites.

Smirnov IV, Golovin AV, Chatziefthimiou SD, Stepanova AV, Peng Y, Zolotareva OI, Belogurov AA Jr, Kurkova IN, Ponomarenko NA, Wilmanns M, Blackburn GM, Gabibov AG, Lerner RA.

Sci Adv. 2016 Oct 19;2(10):e1501695. eCollection 2016 Oct.

8.

Erratum to: Heterodimer HLA-DM Fused with Constant Fragment of the Heavy Chain of the Human Immunoglobulin Accelerates Influenza Hemagglutinin Peptide HA306-318 Loading to HLA-DR1.

Mamedov AE, Ponomarenko NA, Belogurov AA Jr, Gabibov AG.

Bull Exp Biol Med. 2016 Jul;161(3):442-446. No abstract available.

PMID:
27520960
9.

[Expression Of DNA-Encoded Antidote to Organophosphorus Toxins in the Methylotrophic Yeast Pichia Pastoris].

Terekhov SS, Bobik TV, Mokrushina YA, Stepanova AV, Aleksandrova NM, Smirnov IV, Belogurov AA, Ponomarenko NA, Gabibov AG.

Prikl Biokhim Mikrobiol. 2016 Mar-Apr;52(2):184-92. Russian.

PMID:
27266247
10.

Heterodimer HLA-DM Fused with Constant Fragment of the Heavy Chain of the Human Immunoglobulin Accelerates Influenza Hemagglutinin HA306-318 Loading to HLA-DR1.

Mamedov AE, Ponomarenko NA, Belogurov AA Jr, Gabibov AG.

Bull Exp Biol Med. 2016 May;161(1):92-5. doi: 10.1007/s10517-016-3353-y. Epub 2016 Jun 6. Erratum in: Bull Exp Biol Med. 2016 Jul;161(3):442-6.

PMID:
27265131
11.

Chemical Polysialylation and In Vivo Tetramerization Improve Pharmacokinetic Characteristics of Recombinant Human Butyrylcholinesterase-Based Bioscavengers.

Terekhov SS, Smirnov IV, Shamborant OG, Bobik TV, Ilyushin DG, Murashev AN, Dyachenko IA, Palikov VA, Knorre VD, Belogurov AA, Ponomarenko NA, Kuzina ES, Genkin DD, Masson P, Gabibov AG.

Acta Naturae. 2015 Oct-Dec;7(4):136-41.

12.

Specific Depletion of Myelin-Reactive B Cells via BCR-Targeting.

Stepanov AV, Belogurov AA Jr, Kothapalli P, Shamborant OG, Knorre VD, Telegin GB, Ovsepyan AA, Ponomarenko NA, Deyev SM, Kaveri SV, Gabibov AG.

Acta Naturae. 2015 Apr-Jun;7(2):74-9.

13.

Excessive Labeling Technique Provides a Highly Sensitive Fluorescent Probe for Real-time Monitoring of Biodegradation of Biopolymer Pharmaceuticals in vivo.

Terekhov SS, Smirnov IV, Shamborant OG, Zenkova MA, Chernolovskaya EL, Gladkikh DV, Murashev AN, Dyachenko IA, Knorre VD, Belogurov AA, Ponomarenko NA, Deyev SM, Vlasov VV, Gabibov AG.

Acta Naturae. 2014 Oct;6(4):54-9.

14.

Heavy-light chain interrelations of MS-associated immunoglobulins probed by deep sequencing and rational variation.

Lomakin YA, Zakharova MY, Stepanov AV, Dronina MA, Smirnov IV, Bobik TV, Pyrkov AY, Tikunova NV, Sharanova SN, Boitsov VM, Vyazmin SY, Kabilov MR, Tupikin AE, Krasnov AN, Bykova NA, Medvedeva YA, Fridman MV, Favorov AV, Ponomarenko NA, Dubina MV, Boyko AN, Vlassov VV, Belogurov AA Jr, Gabibov AG.

Mol Immunol. 2014 Dec;62(2):305-14. doi: 10.1016/j.molimm.2014.01.013. Epub 2014 Feb 16.

15.

Polyreactive monoclonal autoantibodies in multiple sclerosis: functional selection from phage display library and characterization by deep sequencing analysis.

Lomakin YA, Zakharova MY, Belogurov AA, Bykova NA, Dronina MA, Tupikin AE, Knorre VD, Boyko AN, Favorov AV, Kabilov MR, Ponomarenko NA, Gabibov G.

Acta Naturae. 2013 Oct;5(4):94-104.

16.

Immunoproteasome enhances intracellular proteolysis of myelin basic protein.

Kuzina ES, Chernolovskaya EL, Kudriaeva AA, Zenkova MA, Knorre VD, Surina EA, Ponomarenko NA, Bobik TV, Smirnov IV, Bacheva AV, Belogurov AA, Gabibov AG, Vlasov VV.

Dokl Biochem Biophys. 2013 Nov;453:300-3. doi: 10.1134/S1607672913060070. Epub 2014 Jan 3. No abstract available.

PMID:
24385101
17.

Heterogeneous catalysis on the phage surface: Display of active human enteropeptidase.

Gasparian ME, Bobik TV, Kim YV, Ponomarenko NA, Dolgikh DA, Gabibov AG, Kirpichnikov MP.

Biochimie. 2013 Nov;95(11):2076-81. doi: 10.1016/j.biochi.2013.07.020. Epub 2013 Aug 3.

PMID:
23917033
18.

Recombinant human butyrylcholinesterase as a new-age bioscavenger drug: development of the expression system.

Ilyushin DG, Haertley OM, Bobik TV, Shamborant OG, Surina EA, Knorre VD, Masson P, Smirnov IV, Gabibov AG, Ponomarenko NA.

Acta Naturae. 2013 Jan;5(1):73-84.

19.

Chemical polysialylation of human recombinant butyrylcholinesterase delivers a long-acting bioscavenger for nerve agents in vivo.

Ilyushin DG, Smirnov IV, Belogurov AA Jr, Dyachenko IA, Zharmukhamedova TIu, Novozhilova TI, Bychikhin EA, Serebryakova MV, Kharybin ON, Murashev AN, Anikienko KA, Nikolaev EN, Ponomarenko NA, Genkin DD, Blackburn GM, Masson P, Gabibov AG.

Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1243-8. doi: 10.1073/pnas.1211118110. Epub 2013 Jan 7.

20.

Creation of catalytic antibodies metabolizing organophosphate compounds.

Kurkova IN, Smirnov IV, Belogurov AA Jr, Ponomarenko NA, Gabibov AG.

Biochemistry (Mosc). 2012 Oct;77(10):1139-46. doi: 10.1134/S0006297912100069. Review.

21.

Liposome-encapsulated peptides protect against experimental allergic encephalitis.

Belogurov AA Jr, Stepanov AV, Smirnov IV, Melamed D, Bacon A, Mamedov AE, Boitsov VM, Sashchenko LP, Ponomarenko NA, Sharanova SN, Boyko AN, Dubina MV, Friboulet A, Genkin DD, Gabibov AG.

FASEB J. 2013 Jan;27(1):222-31. doi: 10.1096/fj.12-213975. Epub 2012 Oct 9.

22.

[Therapeutic effect of encapsulated into the nanocontainers MBP immunodominant peptides on EAE development in DA rats].

Stepanov AV, Belogurov AA, Mamedov AÉ, Melamed D, Smirnov IV, Kuzina ES, Genkin DD, Boĭko AN, Sharanova SN, Bacon A, Ponomarenko NA, Gabibov AG.

Bioorg Khim. 2012 May-Jun;38(3):306-14. Russian.

PMID:
22997702
23.

Combinatorial antibody library from multiple sclerosis patients reveals antibodies that cross-react with myelin basic protein and EBV antigen.

Gabibov AG, Belogurov AA Jr, Lomakin YA, Zakharova MY, Avakyan ME, Dubrovskaya VV, Smirnov IV, Ivanov AS, Molnar AA, Gurtsevitch VE, Diduk SV, Smirnova KV, Avalle B, Sharanova SN, Tramontano A, Friboulet A, Boyko AN, Ponomarenko NA, Tikunova NV.

FASEB J. 2011 Dec;25(12):4211-21. doi: 10.1096/fj.11-190769. Epub 2011 Aug 22.

PMID:
21859892
24.

Design of targeted B cell killing agents.

Stepanov AV, Belogurov AA Jr, Ponomarenko NA, Stremovskiy OA, Kozlov LV, Bichucher AM, Dmitriev SE, Smirnov IV, Shamborant OG, Balabashin DS, Sashchenko LP, Tonevitsky AG, Friboulet A, Gabibov AG, Deyev SM.

PLoS One. 2011;6(6):e20991. doi: 10.1371/journal.pone.0020991. Epub 2011 Jun 6.

25.

[Expression of the catalytic antibodies in eukaryotic systems].

Zakharov AV, Smirnov IV, Serebriakova MV, Dronina MA, Kaznacheeva AV, Kurkova IN, Belogurov AA, Friboulet A, Ponomarenko NA, Gabibov AG, Bobik TV.

Mol Biol (Mosk). 2011 Jan-Feb;45(1):86-95. Russian.

PMID:
21485500
26.

[Functional degradation of myelin basic protein. Proteomic approach].

Bacheva AV, Belogurov AA, Kuzina ES, Serebriakova MV, Ponomarenko NA, Knorre VD, Govorun VM, Gabibov AG.

Bioorg Khim. 2011 Jan-Feb;37(1):45-54. Russian.

PMID:
21460880
27.

[Diagnostic and pathogenetic implications of the site specificity of antibody proteases in multiple sclerosis].

Salafet OV, Ruzina ND, Ponomarenko NA, Friboulet A, Kimova MV, Shmidt TE, Gabibov AG, Morse HK, Pal'tsev MA, Suchkov SV.

Vestn Ross Akad Med Nauk. 2010;(4):8-15. Review. Russian.

PMID:
20540348
28.

RNA-hydrolyzing activity of human serum albumin and its recombinant analogue.

Gerasimova YV, Bobik TV, Ponomarenko NA, Shakirov MM, Zenkova MA, Tamkovich NV, Popova TV, Knorre DG, Godovikova TS.

Bioorg Med Chem Lett. 2010 Feb 15;20(4):1427-31. doi: 10.1016/j.bmcl.2009.12.095. Epub 2010 Jan 4.

PMID:
20079637
29.

Suppression of ongoing experimental allergic encephalomyelitis in DA rats by novel peptide drug, structural part of human myelin basic protein 46-62.

Belogurov AA Jr, Zargarova TA, Turobov VI, Novikova NI, Favorova OO, Ponomarenko NA, Gabibov AG.

Autoimmunity. 2009 May;42(4):362-4.

PMID:
19811302
30.

Antibodies-antidotes against organophosphorus compounds.

Kurkova IN, Reshetnyak AV, Durova OM, Knorre VD, Tramontano A, Friboulet A, Ponomarenko NA, Gabibov AG, Smirnov IV.

Dokl Biochem Biophys. 2009 Mar-Apr;425:94-7. No abstract available.

PMID:
19496331
31.

Site-specific degradation of myelin basic protein by the proteasome.

Belogurov AA Jr, Ponomarenko NA, Govorun VM, Gabibov AG, Bacheva AV.

Dokl Biochem Biophys. 2009 Mar-Apr;425:68-72. No abstract available.

PMID:
19496324
32.

Analysis of myelin basic protein fragmentation by proteasome.

Bacheva AV, Belogurov AA, Ponomarenko NA, Knorre VD, Govorun VM, Serebryakova MV, Gabibov AG.

Acta Naturae. 2009 Apr;1(1):84-7.

33.

Strategies for induction of catalytic antibodies toward HIV-1 glycoprotein gp120 in autoimmune prone mice.

Durova OM, Vorobiev II, Smirnov IV, Reshetnyak AV, Telegin GB, Shamborant OG, Orlova NA, Genkin DD, Bacon A, Ponomarenko NA, Friboulet A, Gabibov AG.

Mol Immunol. 2009 Nov;47(1):87-95. doi: 10.1016/j.molimm.2008.12.020. Epub 2009 Feb 6.

PMID:
19201029
34.

The antiidiotypic approach to obtaining a proteolytic antibody.

Smirnov IV, Vorobiev II, Friboulet A, Avalle B, Thomas D, Knorre VD, Gabibov AG, Ponomarenko NA.

Dokl Biochem Biophys. 2008 May-Jun;420:105-7. No abstract available.

PMID:
18680902
35.

[Expression of human serum albumin in metylotrophic yeast Pichia pastoris and its structural and functional analysis].

Bobik TV, Vorob'ev II, Ponomarenko NA, Gabibov AG, Miroshnikov AI.

Bioorg Khim. 2008 Jan-Feb;34(1):56-62. Russian.

PMID:
18365738
36.

Recognition and degradation of myelin basic protein peptides by serum autoantibodies: novel biomarker for multiple sclerosis.

Belogurov AA Jr, Kurkova IN, Friboulet A, Thomas D, Misikov VK, Zakharova MY, Suchkov SV, Kotov SV, Alehin AI, Avalle B, Souslova EA, Morse HC 3rd, Gabibov AG, Ponomarenko NA.

J Immunol. 2008 Jan 15;180(2):1258-67.

37.

Routes to covalent catalysis by reactive selection for nascent protein nucleophiles.

Reshetnyak AV, Armentano MF, Ponomarenko NA, Vizzuso D, Durova OM, Ziganshin R, Serebryakova M, Govorun V, Gololobov G, Morse HC 3rd, Friboulet A, Makker SP, Gabibov AG, Tramontano A.

J Am Chem Soc. 2007 Dec 26;129(51):16175-82. Epub 2007 Nov 29.

38.

Anti-idiotypic antibody mimics proteolytic function of parent antigen.

Ponomarenko NA, Pillet D, Paon M, Vorobiev II, Smirnov IV, Adenier H, Avalle B, Kolesnikov AV, Kozyr AV, Thomas D, Gabibov AG, Friboulet A.

Biochemistry. 2007 Dec 18;46(50):14598-609. Epub 2007 Nov 20.

PMID:
18020454
39.

Mechanism-dependent selection of immunoglobulin gene library for obtaining covalent biocatalysts.

Reshetnyak AV, Armentano MF, Morse HC, Friboulet A, Makker SP, Tramontano A, Knorre VD, Gabibov AG, Ponomarenko NA.

Dokl Biochem Biophys. 2007 Jul-Aug;415:179-82. No abstract available.

PMID:
17933329
40.

[Antibody-mediated proteolysis of myelin-associated proteins as a new mechanism of control over demyelinization processes in multiple sclerosis].

Suchkov SV, Vvedenskaia OIu, Vostrikova IL, Gabibov AG, Kimova MV, Burdakova IuA, Ponomarenko NA, Pal'tsev MA.

Vestn Ross Akad Med Nauk. 2007;(7):32-6. Review. Russian.

PMID:
17722295
41.

Substrate specificity of catalytic autoantibodies in neurodegenerative processes.

Belogurov AA, Kurkova IN, Misikov VK, Suchkov SV, Telegin GB, Alekhine AI, Goncharov NG, Knorre VD, Gabibov AG, Ponomarenko NA.

Dokl Biochem Biophys. 2007 Mar-Apr;413:61-4. No abstract available.

PMID:
17546954
42.

[Catalytic autoantibodies--a new molecular instrument in cardiology and ophthalmology].

Mal'tsev KA, Khitrov AN, Vvedenskaia OIu, Ponomarenko NA, Isaeva MA, Klimova MV, Tret'iak EB, Shogenov ZS, Alekberova ZS, Gabibov SV, Suchkov SV.

Ter Arkh. 2006;78(11):70-6. Russian.

PMID:
17195532
43.

[Catalytic autoantibodies as a new molecular instrument in rheumatological practice].

Khitrov AN, Mal'tsev KA, Vvedenskaia OIu, Ponomarenko NA, Isaeva MA, Kimova MV, Tret'iak EB, Shogenov ZS, Alekberova ZS, Gabibov AG, Suchkov SV.

Ter Arkh. 2006;78(6):59-66. Russian.

PMID:
16881365
44.

Catalytic autoantibodies in clinical autoimmunity and modern medicine.

Gabibov AG, Ponomarenko NA, Tretyak EB, Paltsev MA, Suchkov SV.

Autoimmun Rev. 2006 May;5(5):324-30. Epub 2006 Feb 28. Review.

PMID:
16782557
45.

[DNA-abzymes in rheumatoid arthritis: pathogenetic and clinical significance].

Khitrov AN, Romadanova NB, Ogneva EA, Naumova TE, Alekberova ZS, Vorob'ev II, Gabibov AG, Ponomarenko NA, Suchkov SV.

Ter Arkh. 2005;77(11):75-80. Russian.

PMID:
16404867
46.

Induction of a protein-targeted catalytic response in autoimmune prone mice: antibody-mediated cleavage of HIV-1 glycoprotein GP120.

Ponomarenko NA, Vorobiev II, Alexandrova ES, Reshetnyak AV, Telegin GB, Khaidukov SV, Avalle B, Karavanov A, Morse HC 3rd, Thomas D, Friboulet A, Gabibov AG.

Biochemistry. 2006 Jan 10;45(1):324-30.

PMID:
16388609
47.

Autoantibodies to myelin basic protein catalyze site-specific degradation of their antigen.

Ponomarenko NA, Durova OM, Vorobiev II, Belogurov AA Jr, Kurkova IN, Petrenko AG, Telegin GB, Suchkov SV, Kiselev SL, Lagarkova MA, Govorun VM, Serebryakova MV, Avalle B, Tornatore P, Karavanov A, Morse HC 3rd, Thomas D, Friboulet A, Gabibov AG.

Proc Natl Acad Sci U S A. 2006 Jan 10;103(2):281-6. Epub 2005 Dec 30.

48.

Catalytic activity of autoantibodies toward myelin basic protein correlates with the scores on the multiple sclerosis expanded disability status scale.

Ponomarenko NA, Durova OM, Vorobiev II, Belogurov AA, Telegin GB, Suchkov SV, Misikov VK, Morse HC 3rd, Gabibov AG.

Immunol Lett. 2006 Feb 28;103(1):45-50. Epub 2005 Nov 4.

PMID:
16297986
49.

[Catalytic autoantibodies in autoimmune myocarditis: clinical and pathogenetic implications].

Kalinina EV, Ponomarenko NA, Durova OM, Paleev FN, Vorob'ev II, Kekenadze NN, Shogenov ZS, Zemtsova ME, Gnuchev NV, Gabibov AG.

Ter Arkh. 2005;77(9):65-70. Russian.

PMID:
16281493
50.

[Achievements and prospects of clinical abzymology].

Suchkov SV, Alekberova ZS, Paleev FN, Naumova TE, Misikov VK, Kriazheva ES, Ponomarenko NA, Gabivov AG.

Vestn Ross Akad Med Nauk. 2005;(9):38-43. Review. Russian.

PMID:
16250330

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