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Items: 1 to 50 of 118


Effect of sludge features and extraction-esterification technology on the synthesis of biodiesel from secondary wastewater treatment sludges.

Patiño Y, Mantecón LG, Polo S, Faba L, Díaz E, Ordóñez S.

Bioresour Technol. 2018 Jan;247:209-216. doi: 10.1016/j.biortech.2017.09.058. Epub 2017 Sep 10.


Targeting HECT-type E3 ligases - insights from catalysis, regulation and inhibitors.

Fajner V, Maspero E, Polo S.

FEBS Lett. 2017 Sep;591(17):2636-2647. doi: 10.1002/1873-3468.12775. Epub 2017 Aug 20. Review.


Reticulon 3-dependent ER-PM contact sites control EGFR nonclathrin endocytosis.

Caldieri G, Barbieri E, Nappo G, Raimondi A, Bonora M, Conte A, Verhoef LGGC, Confalonieri S, Malabarba MG, Bianchi F, Cuomo A, Bonaldi T, Martini E, Mazza D, Pinton P, Tacchetti C, Polo S, Di Fiore PP, Sigismund S.

Science. 2017 May 12;356(6338):617-624. doi: 10.1126/science.aah6152.


Choreography of parental histones in damaged chromatin.

Dabin J, Polo SE.

Nucleus. 2017 May 4;8(3):255-260. doi: 10.1080/19491034.2017.1292192. Epub 2017 Feb 23. Review.


Genome and Epigenome Maintenance by Keeping Histone Turnover in Check.

Fortuny A, Polo SE.

Mol Cell. 2017 Apr 6;66(1):3-4. doi: 10.1016/j.molcel.2017.03.015.


Switching genes to silent mode near DNA double-strand breaks.

Polo SE.

EMBO Rep. 2017 May;18(5):659-660. doi: 10.15252/embr.201744052. Epub 2017 Mar 23. No abstract available.


HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation.

Myant KB, Cammareri P, Hodder MC, Wills J, Von Kriegsheim A, Győrffy B, Rashid M, Polo S, Maspero E, Vaughan L, Gurung B, Barry E, Malliri A, Camargo F, Adams DJ, Iavarone A, Lasorella A, Sansom OJ.

EMBO Mol Med. 2017 Feb;9(2):181-197. doi: 10.15252/emmm.201606684.


Real-Time Tracking of Parental Histones Reveals Their Contribution to Chromatin Integrity Following DNA Damage.

Adam S, Dabin J, Chevallier O, Leroy O, Baldeyron C, Corpet A, Lomonte P, Renaud O, Almouzni G, Polo SE.

Mol Cell. 2016 Oct 6;64(1):65-78. doi: 10.1016/j.molcel.2016.08.019. Epub 2016 Sep 15.


In Vitro Ubiquitination: Self-Ubiquitination, Chain Formation, and Substrate Ubiquitination Assays.

Maspero E, Polo S.

Methods Mol Biol. 2016;1449:153-60. doi: 10.1007/978-1-4939-3756-1_7.


Strategies to Detect Endogenous Ubiquitination of a Target Mammalian Protein.

Sigismund S, Polo S.

Methods Mol Biol. 2016;1449:143-51. doi: 10.1007/978-1-4939-3756-1_6. Review.


Epigenome Maintenance in Response to DNA Damage.

Dabin J, Fortuny A, Polo SE.

Mol Cell. 2016 Jun 2;62(5):712-27. doi: 10.1016/j.molcel.2016.04.006. Review.


Myosin VI Contains a Compact Structural Motif that Binds to Ubiquitin Chains.

He F, Wollscheid HP, Nowicka U, Biancospino M, Valentini E, Ehlinger A, Acconcia F, Magistrati E, Polo S, Walters KJ.

Cell Rep. 2016 Mar 22;14(11):2683-94. doi: 10.1016/j.celrep.2016.01.079. Epub 2016 Mar 10.


Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain.

Wollscheid HP, Biancospino M, He F, Magistrati E, Molteni E, Lupia M, Soffientini P, Rottner K, Cavallaro U, Pozzoli U, Mapelli M, Walters KJ, Polo S.

Nat Struct Mol Biol. 2016 Apr;23(4):300-308. doi: 10.1038/nsmb.3187. Epub 2016 Mar 7.


USP9X Controls EGFR Fate by Deubiquitinating the Endocytic Adaptor Eps15.

Savio MG, Wollscheid N, Cavallaro E, Algisi V, Di Fiore PP, Sigismund S, Maspero E, Polo S.

Curr Biol. 2016 Jan 25;26(2):173-83. doi: 10.1016/j.cub.2015.11.050. Epub 2015 Dec 31.


Chromatin dynamics after DNA damage: The legacy of the access-repair-restore model.

Polo SE, Almouzni G.

DNA Repair (Amst). 2015 Dec;36:114-21. doi: 10.1016/j.dnarep.2015.09.014. Epub 2015 Sep 15. Review.


Quantitative analysis reveals how EGFR activation and downregulation are coupled in normal but not in cancer cells.

Capuani F, Conte A, Argenzio E, Marchetti L, Priami C, Polo S, Di Fiore PP, Sigismund S, Ciliberto A.

Nat Commun. 2015 Aug 12;6:7999. doi: 10.1038/ncomms8999.


Clostridium amazonense sp. nov. an obliqately anaerobic bacterium isolated from a remote Amazonian community in Peru.

O'Neal L, Obregón-Tito AJ, Tito RY, Ozga AT, Polo SI, Lewis CM Jr, Lawson PA.

Anaerobe. 2015 Oct;35(Pt B):33-7. doi: 10.1016/j.anaerobe.2015.06.005. Epub 2015 Jun 26.


Genome Analysis of Latin American Cervical Cancer: Frequent Activation of the PIK3CA Pathway.

Lou H, Villagran G, Boland JF, Im KM, Polo S, Zhou W, Odey U, Juárez-Torres E, Medina-Martínez I, Roman-Basaure E, Mitchell J, Roberson D, Sawitzke J, Garland L, Rodríguez-Herrera M, Wells D, Troyer J, Pinto FC, Bass S, Zhang X, Castillo M, Gold B, Morales H, Yeager M, Berumen J, Alvirez E, Gharzouzi E, Dean M.

Clin Cancer Res. 2015 Dec 1;21(23):5360-70. doi: 10.1158/1078-0432.CCR-14-1837. Epub 2015 Jun 16.


Chromatin plasticity in response to DNA damage: The shape of things to come.

Adam S, Dabin J, Polo SE.

DNA Repair (Amst). 2015 Aug;32:120-126. doi: 10.1016/j.dnarep.2015.04.022. Epub 2015 May 1. Review.


Imaging local deposition of newly synthesized histones in UVC-damaged chromatin.

Adam S, Dabin J, Bai SK, Polo SE.

Methods Mol Biol. 2015;1288:337-47. doi: 10.1007/978-1-4939-2474-5_19.


Structural and functional framework for the autoinhibition of Nedd4-family ubiquitin ligases.

Mari S, Ruetalo N, Maspero E, Stoffregen MC, Pasqualato S, Polo S, Wiesner S.

Structure. 2014 Nov 4;22(11):1639-49. doi: 10.1016/j.str.2014.09.006. Epub 2014 Oct 30.


Tyrosine phosphorylation of NEDD4 activates its ubiquitin ligase activity.

Persaud A, Alberts P, Mari S, Tong J, Murchie R, Maspero E, Safi F, Moran MF, Polo S, Rotin D.

Sci Signal. 2014 Oct 7;7(346):ra95. doi: 10.1126/scisignal.2005290.


Blurring the line between the DNA damage response and transcription: the importance of chromatin dynamics.

Adam S, Polo SE.

Exp Cell Res. 2014 Nov 15;329(1):148-53. doi: 10.1016/j.yexcr.2014.07.017. Epub 2014 Jul 22. Review.


Membrane trafficking. Nucleoside diphosphate kinases fuel dynamin superfamily proteins with GTP for membrane remodeling.

Boissan M, Montagnac G, Shen Q, Griparic L, Guitton J, Romao M, Sauvonnet N, Lagache T, Lascu I, Raposo G, Desbourdes C, Schlattner U, Lacombe ML, Polo S, van der Bliek AM, Roux A, Chavrier P.

Science. 2014 Jun 27;344(6191):1510-5. doi: 10.1126/science.1253768.


Reshaping chromatin after DNA damage: the choreography of histone proteins.

Polo SE.

J Mol Biol. 2015 Feb 13;427(3):626-36. doi: 10.1016/j.jmb.2014.05.025. Epub 2014 Jun 2. Review.


Keeping EGFR signaling in check: ubiquitin is the guardian.

Polo S, Di Fiore PP, Sigismund S.

Cell Cycle. 2014;13(5):681-2. doi: 10.4161/cc.27855. Epub 2014 Jan 21. No abstract available.


Expression of c-erbB-2 in breast cancer cell lines as experimental receptor of magnetic nanoparticles.

Silva JG, Sánchez V, Polo SM, González CA.

Conf Proc IEEE Eng Med Biol Soc. 2013;2013:4498-501. doi: 10.1109/EMBC.2013.6610546.


Transcription recovery after DNA damage requires chromatin priming by the H3.3 histone chaperone HIRA.

Adam S, Polo SE, Almouzni G.

Cell. 2013 Sep 26;155(1):94-106. doi: 10.1016/j.cell.2013.08.029.


Threshold-controlled ubiquitination of the EGFR directs receptor fate.

Sigismund S, Algisi V, Nappo G, Conte A, Pascolutti R, Cuomo A, Bonaldi T, Argenzio E, Verhoef LG, Maspero E, Bianchi F, Capuani F, Ciliberto A, Polo S, Di Fiore PP.

EMBO J. 2013 Jul 31;32(15):2140-57. doi: 10.1038/emboj.2013.149. Epub 2013 Jun 25.


The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation.

Sorrentino V, Nelson JK, Maspero E, Marques AR, Scheer L, Polo S, Zelcer N.

J Lipid Res. 2013 Aug;54(8):2174-84. doi: 10.1194/jlr.M037713. Epub 2013 Jun 3.


Volumetric electromagnetic phase-shift spectroscopy of brain edema and hematoma.

Gonzalez CA, Valencia JA, Mora A, Gonzalez F, Velasco B, Porras MA, Salgado J, Polo SM, Hevia-Montiel N, Cordero S, Rubinsky B.

PLoS One. 2013 May 14;8(5):e63223. doi: 10.1371/journal.pone.0063223. Print 2013.


Structure of a ubiquitin-loaded HECT ligase reveals the molecular basis for catalytic priming.

Maspero E, Valentini E, Mari S, Cecatiello V, Soffientini P, Pasqualato S, Polo S.

Nat Struct Mol Biol. 2013 Jun;20(6):696-701. doi: 10.1038/nsmb.2566. Epub 2013 May 5.


Ubiquitination dynamics in the early-branching eukaryote Giardia intestinalis.

Niño CA, Chaparro J, Soffientini P, Polo S, Wasserman M.

Microbiologyopen. 2013 Jun;2(3):525-39. doi: 10.1002/mbo3.88. Epub 2013 Apr 23.


Fine-tuning the p53 response to DNA damage: a new piece in the puzzle.

Polo SE.

Cell Cycle. 2013 May 1;12(9):1337-8. doi: 10.4161/cc.24669. Epub 2013 Apr 15. No abstract available.


Chromatin dynamics during nucleotide excision repair: histones on the move.

Adam S, Polo SE.

Int J Mol Sci. 2012;13(9):11895-911. doi: 10.3390/ijms130911895. Epub 2012 Sep 19. Review.


Possible positive selection for an arsenic-protective haplotype in humans.

Schlebusch CM, Lewis CM Jr, Vahter M, Engström K, Tito RY, Obregón-Tito AJ, Huerta D, Polo SI, Medina ÁC, Brutsaert TD, Concha G, Jakobsson M, Broberg K.

Environ Health Perspect. 2013 Jan;121(1):53-8. doi: 10.1289/ehp.1205504. Epub 2012 Oct 16.


Prime, repair, restore: the active role of chromatin in the DNA damage response.

Soria G, Polo SE, Almouzni G.

Mol Cell. 2012 Jun 29;46(6):722-34. doi: 10.1016/j.molcel.2012.06.002. Review.


A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase.

Gatti M, Pinato S, Maspero E, Soffientini P, Polo S, Penengo L.

Cell Cycle. 2012 Jul 1;11(13):2538-44. doi: 10.4161/cc.20919. Epub 2012 Jul 1.


Signaling-mediated control of ubiquitin ligases in endocytosis.

Polo S.

BMC Biol. 2012 Mar 15;10:25. doi: 10.1186/1741-7007-10-25. Review.


Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair.

Polo SE, Blackford AN, Chapman JR, Baskcomb L, Gravel S, Rusch A, Thomas A, Blundred R, Smith P, Kzhyshkowska J, Dobner T, Taylor AM, Turnell AS, Stewart GS, Grand RJ, Jackson SP.

Mol Cell. 2012 Feb 24;45(4):505-16. doi: 10.1016/j.molcel.2011.12.035.


Endocytosis and signaling: cell logistics shape the eukaryotic cell plan.

Sigismund S, Confalonieri S, Ciliberto A, Polo S, Scita G, Di Fiore PP.

Physiol Rev. 2012 Jan;92(1):273-366. doi: 10.1152/physrev.00005.2011. Review.


USP15 is a deubiquitylating enzyme for receptor-activated SMADs.

Inui M, Manfrin A, Mamidi A, Martello G, Morsut L, Soligo S, Enzo E, Moro S, Polo S, Dupont S, Cordenonsi M, Piccolo S.

Nat Cell Biol. 2011 Sep 25;13(11):1368-75. doi: 10.1038/ncb2346.


Identification of cis-acting elements in the 3'-untranslated region of the dengue virus type 2 RNA that modulate translation and replication.

Manzano M, Reichert ED, Polo S, Falgout B, Kasprzak W, Shapiro BA, Padmanabhan R.

J Biol Chem. 2011 Jun 24;286(25):22521-34. doi: 10.1074/jbc.M111.234302. Epub 2011 Apr 22.


Evolution of attenuating mutations in dengue-2 strain S16803 PDK50 vaccine and comparison of growth kinetics with parent virus.

Kelly EP, Polo S, Sun W, Falgout B.

Virus Genes. 2011 Aug;43(1):18-26. doi: 10.1007/s11262-011-0602-z. Epub 2011 Apr 3.


Replication stress induces 53BP1-containing OPT domains in G1 cells.

Harrigan JA, Belotserkovskaya R, Coates J, Dimitrova DS, Polo SE, Bradshaw CR, Fraser P, Jackson SP.

J Cell Biol. 2011 Apr 4;193(1):97-108. doi: 10.1083/jcb.201011083. Epub 2011 Mar 28.


Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation.

Maspero E, Mari S, Valentini E, Musacchio A, Fish A, Pasqualato S, Polo S.

EMBO Rep. 2011 Apr;12(4):342-9. doi: 10.1038/embor.2011.21. Epub 2011 Mar 11.


Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications.

Polo SE, Jackson SP.

Genes Dev. 2011 Mar 1;25(5):409-33. doi: 10.1101/gad.2021311. Review.


Proteomic snapshot of the EGF-induced ubiquitin network.

Argenzio E, Bange T, Oldrini B, Bianchi F, Peesari R, Mari S, Di Fiore PP, Mann M, Polo S.

Mol Syst Biol. 2011 Jan 18;7:462. doi: 10.1038/msb.2010.118.


Clinical significance and prognostic value of chromatin assembly factor-1 overexpression in human solid tumours.

Polo SE, Theocharis SE, Grandin L, Gambotti L, Antoni G, Savignoni A, Asselain B, Patsouris E, Almouzni G.

Histopathology. 2010 Nov;57(5):716-24. doi: 10.1111/j.1365-2559.2010.03681.x.


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