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Items: 1 to 50 of 204

1.

Temporal Layering of Signaling Effectors Drives Chromatin Remodeling during Hair Follicle Stem Cell Lineage Progression.

Adam RC, Yang H, Ge Y, Lien WH, Wang P, Zhao Y, Polak L, Levorse J, Baksh SC, Zheng D, Fuchs E.

Cell Stem Cell. 2018 Mar 1;22(3):398-413.e7. doi: 10.1016/j.stem.2017.12.004. Epub 2018 Jan 11.

PMID:
29337183
2.

How much is too much medicine?

Polak L.

BMJ. 2017 Oct 20;359:j4863. doi: 10.1136/bmj.j4863. No abstract available.

PMID:
29054979
3.

Inflammatory memory sensitizes skin epithelial stem cells to tissue damage.

Naik S, Larsen SB, Gomez NC, Alaverdyan K, Sendoel A, Yuan S, Polak L, Kulukian A, Chai S, Fuchs E.

Nature. 2017 Oct 26;550(7677):475-480. doi: 10.1038/nature24271. Epub 2017 Oct 18.

4.

Stem Cell Lineage Infidelity Drives Wound Repair and Cancer.

Ge Y, Gomez NC, Adam RC, Nikolova M, Yang H, Verma A, Lu CP, Polak L, Yuan S, Elemento O, Fuchs E.

Cell. 2017 May 4;169(4):636-650.e14. doi: 10.1016/j.cell.2017.03.042. Epub 2017 Apr 20.

PMID:
28434617
5.

The Impact of a Brief Embedded Mindfulness-Based Program for Veterinary Students.

Correia HM, Smith AD, Murray S, Polak LS, Williams B, Cake MA.

J Vet Med Educ. Spring 2017;44(1):125-133. doi: 10.3138/jvme.0116-026R.

PMID:
28206840
6.

Spatiotemporal antagonism in mesenchymal-epithelial signaling in sweat versus hair fate decision.

Lu CP, Polak L, Keyes BE, Fuchs E.

Science. 2016 Dec 23;354(6319). pii: aah6102. doi: 10.1126/science.aah6102.

7.

Impaired Epidermal to Dendritic T Cell Signaling Slows Wound Repair in Aged Skin.

Keyes BE, Liu S, Asare A, Naik S, Levorse J, Polak L, Lu CP, Nikolova M, Pasolli HA, Fuchs E.

Cell. 2016 Nov 17;167(5):1323-1338.e14. doi: 10.1016/j.cell.2016.10.052.

8.

What is wrong with 'being a pill-taker'? The special case of statins.

Polak L.

Sociol Health Illn. 2017 May;39(4):599-613. doi: 10.1111/1467-9566.12509. Epub 2016 Nov 16.

PMID:
27862018
9.

Preventing probe induced topography correlated artifacts in Kelvin Probe Force Microscopy.

Polak L, Wijngaarden RJ.

Ultramicroscopy. 2016 Dec;171:158-165. doi: 10.1016/j.ultramic.2016.09.014. Epub 2016 Sep 20.

PMID:
27690346
10.

Oral bioaccessibility of inorganic contaminants in waste dusts generated by laterite Ni ore smelting.

Ettler V, Polák L, Mihaljevič M, Ratié G, Garnier J, Quantin C.

Environ Geochem Health. 2016 Sep 14. [Epub ahead of print]

PMID:
27629409
11.

Using Joint Interviews to Add Analytic Value.

Polak L, Green J.

Qual Health Res. 2016 Oct;26(12):1638-48. doi: 10.1177/1049732315580103. Epub 2015 Apr 7. Review.

PMID:
25850721
12.

Using quantitative risk information in decisions about statins: a qualitative study in a community setting.

Polak L, Green J.

Br J Gen Pract. 2015 Apr;65(633):e264-9. doi: 10.3399/bjgp15X684433.

13.

Pioneer factors govern super-enhancer dynamics in stem cell plasticity and lineage choice.

Adam RC, Yang H, Rockowitz S, Larsen SB, Nikolova M, Oristian DS, Polak L, Kadaja M, Asare A, Zheng D, Fuchs E.

Nature. 2015 May 21;521(7552):366-70. doi: 10.1038/nature14289. Epub 2015 Mar 18.

14.

Beware of medicalising the fear of uncertainty and death.

Polak L.

BMJ. 2014 Nov 25;349:g7077. doi: 10.1136/bmj.g7077. No abstract available.

PMID:
25425082
15.

The lectin BJcuL induces apoptosis through TRAIL expression, caspase cascade activation and mitochondrial membrane permeability in a human colon adenocarcinoma cell line.

Damasio Dde C, Nolte S, Polak LP, Brandt AP, Bonan NB, Zischler L, Stuelp-Campelo PM, Cadena SM, Noronha Ld, Elífio-Esposito SL, Moreno-Amaral AN.

Toxicon. 2014 Nov;90:299-307. doi: 10.1016/j.toxicon.2014.08.062. Epub 2014 Sep 3.

PMID:
25194746
16.

Communicating risk.

Polak L.

Br J Gen Pract. 2014 Jun;64(623):277. doi: 10.3399/bjgp14X680017. No abstract available.

17.

Amantadine augmentation therapy for obsessive compulsive patients resistant to SSRIs-an open-label study.

Stryjer R, Budnik D, Ebert T, Green T, Polak L, Weizman S, Spivak B.

Clin Neuropharmacol. 2014 May-Jun;37(3):79-81. doi: 10.1097/WNF.0000000000000029.

PMID:
24824662
18.

Note: switching crosstalk on and off in Kelvin Probe Force Microscopy.

Polak L, de Man S, Wijngaarden RJ.

Rev Sci Instrum. 2014 Apr;85(4):046111. doi: 10.1063/1.4873331.

PMID:
24784689
19.

SOX9: a stem cell transcriptional regulator of secreted niche signaling factors.

Kadaja M, Keyes BE, Lin M, Pasolli HA, Genander M, Polak L, Stokes N, Zheng D, Fuchs E.

Genes Dev. 2014 Feb 15;28(4):328-41. doi: 10.1101/gad.233247.113.

20.

In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators.

Lien WH, Polak L, Lin M, Lay K, Zheng D, Fuchs E.

Nat Cell Biol. 2014 Feb;16(2):179-90. doi: 10.1038/ncb2903. Epub 2014 Jan 26.

21.

Helping patients make the right decisions about treatment.

Polak L.

BMJ. 2013 Oct 9;347:f6025. doi: 10.1136/bmj.f6025. No abstract available.

PMID:
24108165
22.

Architectural niche organization by LHX2 is linked to hair follicle stem cell function.

Folgueras AR, Guo X, Pasolli HA, Stokes N, Polak L, Zheng D, Fuchs E.

Cell Stem Cell. 2013 Sep 5;13(3):314-27. doi: 10.1016/j.stem.2013.06.018.

23.

Making health habitual.

Polak L.

Br J Gen Pract. 2013 Feb;63(607):70-1. doi: 10.3399/bjgp13X662966. No abstract available.

24.

Identification of stem cell populations in sweat glands and ducts reveals roles in homeostasis and wound repair.

Lu CP, Polak L, Rocha AS, Pasolli HA, Chen SC, Sharma N, Blanpain C, Fuchs E.

Cell. 2012 Jul 6;150(1):136-50. doi: 10.1016/j.cell.2012.04.045.

25.

We can learn from disciplines outside medicine.

Polak L.

BMJ. 2012 Jun 25;344:e4293. doi: 10.1136/bmj.e4293. No abstract available.

PMID:
22734093
26.

Communicating risk to patients and the public.

Polak L.

Br J Gen Pract. 2012 May;62(598):240. doi: 10.3399/bjgp12X641410. No abstract available.

27.

Evidence supports the need to offer treatment as part of shared decision making.

Polak L.

BMJ. 2012 Jan 31;344:e727. doi: 10.1136/bmj.e727. No abstract available.

PMID:
22293378
28.

Are the serious problems in cancer survival partly rooted in gatekeeper principles?

Polak L.

Br J Gen Pract. 2011 Nov;61(592):661; author reply 661-2. doi: 10.3399/bjgp11X606500. No abstract available.

29.

Genome-wide maps of histone modifications unwind in vivo chromatin states of the hair follicle lineage.

Lien WH, Guo X, Polak L, Lawton LN, Young RA, Zheng D, Fuchs E.

Cell Stem Cell. 2011 Sep 2;9(3):219-32. doi: 10.1016/j.stem.2011.07.015.

30.

Specific microRNAs are preferentially expressed by skin stem cells to balance self-renewal and early lineage commitment.

Zhang L, Stokes N, Polak L, Fuchs E.

Cell Stem Cell. 2011 Mar 4;8(3):294-308. doi: 10.1016/j.stem.2011.01.014.

31.

Anomalous independence of multiple exciton generation on different group IV-VI quantum dot architectures.

Trinh MT, Polak L, Schins JM, Houtepen AJ, Vaxenburg R, Maikov GI, Grinbom G, Midgett AG, Luther JM, Beard MC, Nozik AJ, Bonn M, Lifshitz E, Siebbeles LD.

Nano Lett. 2011 Apr 13;11(4):1623-9. doi: 10.1021/nl200014g. Epub 2011 Feb 24.

PMID:
21348493
32.

Ventricular septal defect complicating acute myocardial infarction-still an unsolved problem in the invasive treatment era.

Ledakowicz-Polak A, Polak L, Zielińska M.

Cardiovasc Pathol. 2011 Mar-Apr;20(2):93-8. doi: 10.1016/j.carpath.2010.01.008. Epub 2010 Feb 25.

PMID:
20185340
33.

Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia.

Nguyen H, Merrill BJ, Polak L, Nikolova M, Rendl M, Shaver TM, Pasolli HA, Fuchs E.

Nat Genet. 2009 Oct;41(10):1068-75. doi: 10.1038/ng.431. Epub 2009 Aug 30.

34.

Prinzmetal's variant angina associated with severe heart rhythm disturbances and syncope: a therapeutic dilemma.

Ledakowicz-Polak A, Ptaszyński P, Polak Ł, Zielińska M.

Cardiol J. 2009;16(3):269-72.

35.

Trazodone for the treatment of sexual dysfunction induced by serotonin reuptake inhibitors: a preliminary open-label study.

Stryjer R, Spivak B, Strous RD, Shiloh R, Harary E, Polak L, Birgen M, Kotler M, Weizman A.

Clin Neuropharmacol. 2009 Mar-Apr;32(2):82-4. doi: 10.1097/WNF.0B013E31816D1CDC.

PMID:
18978492
36.

Hair follicle stem cells are specified and function in early skin morphogenesis.

Nowak JA, Polak L, Pasolli HA, Fuchs E.

Cell Stem Cell. 2008 Jul 3;3(1):33-43. doi: 10.1016/j.stem.2008.05.009.

37.

BMP signaling in dermal papilla cells is required for their hair follicle-inductive properties.

Rendl M, Polak L, Fuchs E.

Genes Dev. 2008 Feb 15;22(4):543-57. doi: 10.1101/gad.1614408.

38.

NFATc1 balances quiescence and proliferation of skin stem cells.

Horsley V, Aliprantis AO, Polak L, Glimcher LH, Fuchs E.

Cell. 2008 Jan 25;132(2):299-310. doi: 10.1016/j.cell.2007.11.047.

40.

Loss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia.

Guasch G, Schober M, Pasolli HA, Conn EB, Polak L, Fuchs E.

Cancer Cell. 2007 Oct;12(4):313-27.

41.

Loss of a quiescent niche but not follicle stem cells in the absence of bone morphogenetic protein signaling.

Kobielak K, Stokes N, de la Cruz J, Polak L, Fuchs E.

Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10063-8. Epub 2007 Jun 6.

42.

Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics.

Schober M, Raghavan S, Nikolova M, Polak L, Pasolli HA, Beggs HE, Reichardt LF, Fuchs E.

J Cell Biol. 2007 Feb 26;176(5):667-80.

43.

Lhx2 maintains stem cell character in hair follicles.

Rhee H, Polak L, Fuchs E.

Science. 2006 Jun 30;312(5782):1946-9.

44.

AP-2alpha: a regulator of EGF receptor signaling and proliferation in skin epidermis.

Wang X, Bolotin D, Chu DH, Polak L, Williams T, Fuchs E.

J Cell Biol. 2006 Jan 30;172(3):409-21.

45.

Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche.

Blanpain C, Lowry WE, Geoghegan A, Polak L, Fuchs E.

Cell. 2004 Sep 3;118(5):635-48.

46.

Tcf3: a transcriptional regulator of axis induction in the early embryo.

Merrill BJ, Pasolli HA, Polak L, Rendl M, García-García MJ, Anderson KV, Fuchs E.

Development. 2004 Jan;131(2):263-74. Epub 2003 Dec 10.

47.

Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA.

Kobielak K, Pasolli HA, Alonso L, Polak L, Fuchs E.

J Cell Biol. 2003 Nov 10;163(3):609-23.

48.

Amantadine as augmentation therapy in the management of treatment-resistant depression.

Stryjer R, Strous RD, Shaked G, Bar F, Feldman B, Kotler M, Polak L, Rosenzcwaig S, Weizman A.

Int Clin Psychopharmacol. 2003 Mar;18(2):93-6.

PMID:
12598820
49.

[A new surgical technic in Bartholin gland cysts].

Polák L, Stencl J.

Cesk Gynekol. 1990 Dec;55(10):757-8. Slovak. No abstract available.

PMID:
2285941
50.

Clonidine in hyperkinetic children.

Polák L, Molcan J.

Act Nerv Super (Praha). 1990 Mar;32(1):66-7. No abstract available.

PMID:
1973018

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