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Items: 8


Inhaled hexadecyl-treprostinil provides pulmonary vasodilator activity at significantly lower plasma concentrations than infused treprostinil.

Chapman RW, Li Z, Corboz MR, Gauani H, Plaunt AJ, Konicek DM, Leifer FG, Laurent CE, Yin H, Salvail D, Dziak C, Perkins WR, Malinin V.

Pulm Pharmacol Ther. 2018 Feb 5. pii: S1094-5539(17)30215-8. doi: 10.1016/j.pupt.2018.02.002. [Epub ahead of print]


Preclinical Pharmacology and Pharmacokinetics of Inhaled Hexadecyl-Treprostinil (C16TR), a Pulmonary Vasodilator Prodrug.

Corboz MR, Li Z, Malinin V, Plaunt AJ, Konicek DM, Leifer FG, Chen KJ, Laurent CE, Yin H, Biernat MC, Salvail D, Zhuang J, Xu F, Curran A, Perkins WR, Chapman RW.

J Pharmacol Exp Ther. 2017 Dec;363(3):348-357. doi: 10.1124/jpet.117.242099. Epub 2017 Sep 13.


Chemically triggered release of 5-aminolevulinic acid from liposomes.

Plaunt AJ, Harmatys KM, Hendrie KA, Musso AJ, Smith BD.

RSC Adv. 2014 Oct 29;4(101):57983-57990.


Evaluation of [¹¹¹In]-labeled zinc-dipicolylamine tracers for SPECT imaging of bacterial infection.

Rice DR, Plaunt AJ, Turkyilmaz S, Smith M, Wang Y, Rusckowski M, Smith BD.

Mol Imaging Biol. 2015 Apr;17(2):204-13. doi: 10.1007/s11307-014-0758-8.


¹⁹F NMR indicator displacement assay using a synthetic receptor with appended paramagnetic relaxation agent.

Plaunt AJ, Clear KJ, Smith BD.

Chem Commun (Camb). 2014 Sep 18;50(72):10499-501. doi: 10.1039/c4cc04159c.


Library synthesis, screening, and discovery of modified Zinc(II)-Bis(dipicolylamine) probe for enhanced molecular imaging of cell death.

Plaunt AJ, Harmatys KM, Wolter WR, Suckow MA, Smith BD.

Bioconjug Chem. 2014 Apr 16;25(4):724-37. doi: 10.1021/bc500003x. Epub 2014 Mar 13.


Enhanced cell death imaging using multivalent zinc(II)-bis(dipicolylamine) fluorescent probes.

Smith BA, Harmatys KM, Xiao S, Cole EL, Plaunt AJ, Wolter W, Suckow MA, Smith BD.

Mol Pharm. 2013 Sep 3;10(9):3296-303. doi: 10.1021/mp300720k. Epub 2013 Aug 5.


Selective non-covalent triggered release from liposomes.

Plaunt AJ, Courbanou MB, Cuison KD, Harmatys KM, Smith BD.

Chem Commun (Camb). 2012 Aug 21;48(65):8123-5. doi: 10.1039/c2cc32962j. Epub 2012 Jul 9.

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