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Items: 13


Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children.

Stein MM, Hrusch CL, Gozdz J, Igartua C, Pivniouk V, Murray SE, Ledford JG, Marques Dos Santos M, Anderson RL, Metwali N, Neilson JW, Maier RM, Gilbert JA, Holbreich M, Thorne PS, Martinez FD, von Mutius E, Vercelli D, Ober C, Sperling AI.

N Engl J Med. 2016 Aug 4;375(5):411-421. doi: 10.1056/NEJMoa1508749.


In utero and postnatal exposure to arsenic alters pulmonary structure and function.

Lantz RC, Chau B, Sarihan P, Witten ML, Pivniouk VI, Chen GJ.

Toxicol Appl Pharmacol. 2009 Feb 15;235(1):105-13. doi: 10.1016/j.taap.2008.11.012. Epub 2008 Nov 27.


WIP regulates signaling via the high affinity receptor for immunoglobulin E in mast cells.

Kettner A, Kumar L, Antón IM, Sasahara Y, de la Fuente M, Pivniouk VI, Falet H, Hartwig JH, Geha RS.

J Exp Med. 2004 Feb 2;199(3):357-68.


Impaired signaling via the high-affinity IgE receptor in Wiskott-Aldrich syndrome protein-deficient mast cells.

Pivniouk VI, Snapper SB, Kettner A, Alenius H, Laouini D, Falet H, Hartwig J, Alt FW, Geha RS.

Int Immunol. 2003 Dec;15(12):1431-40.


Structural requirements of SLP-76 in signaling via the high-affinity immunoglobulin E receptor (Fc epsilon RI) in mast cells.

Kettner A, Pivniouk V, Kumar L, Falet H, Lee JS, Mulligan R, Geha RS.

Mol Cell Biol. 2003 Apr;23(7):2395-406.


The binding site for TRAF2 and TRAF3 but not for TRAF6 is essential for CD40-mediated immunoglobulin class switching.

Jabara H, Laouini D, Tsitsikov E, Mizoguchi E, Bhan A, Castigli E, Dedeoglu F, Pivniouk V, Brodeur S, Geha R.

Immunity. 2002 Sep;17(3):265-76.


Differential role of SLP-76 domains in T cell development and function.

Kumar L, Pivniouk V, de la Fuente MA, Laouini D, Geha RS.

Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):884-9. Epub 2002 Jan 15.


The role of SLP-76 and LAT in lymphocyte development.

Pivniouk VI, Geha RS.

Curr Opin Immunol. 2000 Apr;12(2):173-8. Review.


Adapter proteins SLP-76 and BLNK both are expressed by murine macrophages and are linked to signaling via Fcgamma receptors I and II/III.

Bonilla FA, Fujita RM, Pivniouk VI, Chan AC, Geha RS.

Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1725-30.


Allelic exclusion of the T cell receptor beta locus requires the SH2 domain-containing leukocyte protein (SLP)-76 adaptor protein.

Aifantis I, Pivniouk VI, Gärtner F, Feinberg J, Swat W, Alt FW, von Boehmer H, Geha RS.

J Exp Med. 1999 Oct 18;190(8):1093-102.


SLP-76 deficiency impairs signaling via the high-affinity IgE receptor in mast cells.

Pivniouk VI, Martin TR, Lu-Kuo JM, Katz HR, Oettgen HC, Geha RS.

J Clin Invest. 1999 Jun;103(12):1737-43.


Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76.

Pivniouk V, Tsitsikov E, Swinton P, Rathbun G, Alt FW, Geha RS.

Cell. 1998 Jul 24;94(2):229-38.

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