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Items: 1 to 50 of 195

1.

Turning off NADPH oxidase-2 by impeding p67phox activation in infected mouse macrophages reduced viral entry and inflammation.

Lejal N, Truchet S, Bechor E, Bouguyon E, Khedkar V, Bertho N, Vidic J, Adenot P, Solier S, Pick E, Slama-Schwok A.

Biochim Biophys Acta. 2018 Mar 8;1862(6):1263-1275. doi: 10.1016/j.bbagen.2018.03.004. [Epub ahead of print]

PMID:
29524539
2.

Immunodepletion and Immunopurification as Approaches for CSN Research.

Golan A, Wei N, Pick E.

Methods Mol Biol. 2016;1449:103-16. doi: 10.1007/978-1-4939-3756-1_4.

PMID:
27613030
3.

Yeast as a tool to select inhibitors of the cullin deneddylating enzyme Csn5.

Cirigliano A, Stirpe A, Menta S, Mori M, Dell'Edera D, Pick E, Negri R, Botta B, Rinaldi T.

J Enzyme Inhib Med Chem. 2016 Dec;31(6):1632-7. doi: 10.3109/14756366.2016.1160901. Epub 2016 Mar 30.

PMID:
27028668
4.

Absolute and Relative Activity Values in Assessing the Effect of NADPH Oxidase Inhibitors.

Pick E.

Antioxid Redox Signal. 2015 Nov 20;23(15):1250-1. doi: 10.1089/ars.2015.6470.

PMID:
26566924
5.

Aeromonas chitinase degrades chironomid egg masses.

Laviad S, Golan A, Shaked T, Vaizel-Ohayon D, Halpern M, Pick E.

Environ Microbiol Rep. 2016 Feb;8(1):30-7. doi: 10.1111/1758-2229.12347. Epub 2015 Dec 21.

PMID:
26472256
6.

Base-CP proteasome can serve as a platform for stepwise lid formation.

Yu Z, Livnat-Levanon N, Kleifeld O, Mansour W, Nakasone MA, Castaneda CA, Dixon EK, Fushman D, Reis N, Pick E, Glickman MH.

Biosci Rep. 2015 Jan 27;35(3). pii: e00194. doi: 10.1042/BSR20140173.

7.

A Cys-Gly-Cys triad in the dehydrogenase region of Nox2 plays a key role in the interaction with p67phox.

Dahan I, Smith SM, Pick E.

J Leukoc Biol. 2015 Nov;98(5):859-74. doi: 10.1189/jlb.4A0315-107R. Epub 2015 Jul 9.

PMID:
26160850
8.

Two CGD Families with a Hypomorphic Mutation in the Activation Domain of p67phox.

Roos D, van Buul JD, Tool AT, Matute JD, Marchal CM, Hayee B, Köker MY, de Boer M, van Leeuwen K, Segal AW, Pick E, Dinauer MC.

J Clin Cell Immunol. 2014 Jun 30;5(3). pii: 1000231.

9.

The dehydrogenase region of the NADPH oxidase component Nox2 acts as a protein disulfide isomerase (PDI) resembling PDIA3 with a role in the binding of the activator protein p67 (phox.).

Bechor E, Dahan I, Fradin T, Berdichevsky Y, Zahavi A, Federman Gross A, Rafalowski M, Pick E.

Front Chem. 2015 Feb 4;3:3. doi: 10.3389/fchem.2015.00003. eCollection 2015.

10.

Moonlighting and pleiotropy within two regulators of the degradation machinery: the proteasome lid and the CSN.

Pick E, Bramasole L.

Biochem Soc Trans. 2014 Dec;42(6):1786-91. doi: 10.1042/BST20140227. Review.

PMID:
25399607
11.

Cullin E3 ligases and their rewiring by viral factors.

Mahon C, Krogan NJ, Craik CS, Pick E.

Biomolecules. 2014 Oct 13;4(4):897-930. doi: 10.3390/biom4040897. Review.

12.

Role of the Rho GTPase Rac in the activation of the phagocyte NADPH oxidase: outsourcing a key task.

Pick E.

Small GTPases. 2014;5:e27952. doi: 10.4161/sgtp.27952. Epub 2014 Mar 5. Review.

13.

Targeted degradation of abscisic acid receptors is mediated by the ubiquitin ligase substrate adaptor DDA1 in Arabidopsis.

Irigoyen ML, Iniesto E, Rodriguez L, Puga MI, Yanagawa Y, Pick E, Strickland E, Paz-Ares J, Wei N, De Jaeger G, Rodriguez PL, Deng XW, Rubio V.

Plant Cell. 2014 Feb;26(2):712-28. doi: 10.1105/tpc.113.122234. Epub 2014 Feb 21.

14.

Cell-free NADPH oxidase activation assays: "in vitro veritas".

Pick E.

Methods Mol Biol. 2014;1124:339-403. doi: 10.1007/978-1-62703-845-4_22.

PMID:
24504963
15.

The COP9 signalosome is involved in the regulation of lipid metabolism and of transition metals uptake in Saccharomyces cerevisiae.

Licursi V, Salvi C, De Cesare V, Rinaldi T, Mattei B, Fabbri C, Serino G, Bramasole L, Zimbler JZ, Pick E, Barnes BM, Bard M, Negri R.

FEBS J. 2014 Jan;281(1):175-90. doi: 10.1111/febs.12584. Epub 2013 Nov 25.

16.

COP9 signalosome subunit Csn8 is involved in maintaining proper duration of the G1 phase.

Liu C, Guo LQ, Menon S, Jin D, Pick E, Wang X, Deng XW, Wei N.

J Biol Chem. 2013 Jul 12;288(28):20443-52. doi: 10.1074/jbc.M113.468959. Epub 2013 May 20.

17.

Duplication and familial promiscuity within the proteasome lid and COP9 signalosome kin complexes.

Serino G, Pick E.

Plant Sci. 2013 Apr;203-204:89-97. doi: 10.1016/j.plantsci.2012.12.018. Epub 2013 Jan 5. Review.

PMID:
23415332
18.

Formation of alternative proteasomes: same lady, different cap?

Pick E, Berman TS.

FEBS Lett. 2013 Mar 1;587(5):389-93. doi: 10.1016/j.febslet.2013.01.014. Epub 2013 Jan 17.

19.

The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain.

Pick E, Golan A, Zimbler JZ, Guo L, Sharaby Y, Tsuge T, Hofmann K, Wei N.

PLoS One. 2012;7(8):e43980. doi: 10.1371/journal.pone.0043980. Epub 2012 Aug 30.

20.

Strategies for identifying synthetic peptides to act as inhibitors of NADPH oxidases, or "all that you did and did not want to know about Nox inhibitory peptides".

Dahan I, Pick E.

Cell Mol Life Sci. 2012 Jul;69(14):2283-305. doi: 10.1007/s00018-012-1007-4. Epub 2012 May 6. Review.

PMID:
22562603
21.

Rational design of small molecule inhibitors targeting the Rac GTPase-p67(phox) signaling axis in inflammation.

Bosco EE, Kumar S, Marchioni F, Biesiada J, Kordos M, Szczur K, Meller J, Seibel W, Mizrahi A, Pick E, Filippi MD, Zheng Y.

Chem Biol. 2012 Feb 24;19(2):228-42. doi: 10.1016/j.chembiol.2011.12.017.

22.

Inhibition of NADPH oxidase activation by peptides mapping within the dehydrogenase region of Nox2-A "peptide walking" study.

Dahan I, Molshanski-Mor S, Pick E.

J Leukoc Biol. 2012 Mar;91(3):501-15. doi: 10.1189/jlb.1011507. Epub 2011 Dec 19.

PMID:
22184755
23.

Placental protein 13 and decidual zones of necrosis: an immunologic diversion that may be linked to preeclampsia.

Kliman HJ, Sammar M, Grimpel YI, Lynch SK, Milano KM, Pick E, Bejar J, Arad A, Lee JJ, Meiri H, Gonen R.

Reprod Sci. 2012 Jan;19(1):16-30. doi: 10.1177/1933719111424445. Epub 2011 Oct 11.

PMID:
21989657
24.

G6PC3 mutations are associated with a major defect of glycosylation: a novel mechanism for neutrophil dysfunction.

Hayee B, Antonopoulos A, Murphy EJ, Rahman FZ, Sewell G, Smith BN, McCartney S, Furman M, Hall G, Bloom SL, Haslam SM, Morris HR, Boztug K, Klein C, Winchester B, Pick E, Linch DC, Gale RE, Smith AM, Dell A, Segal AW.

Glycobiology. 2011 Jul;21(7):914-24. doi: 10.1093/glycob/cwr023. Epub 2011 Mar 8.

25.

Dual function of Rpn5 in two PCI complexes, the 26S proteasome and COP9 signalosome.

Yu Z, Kleifeld O, Lande-Atir A, Bsoul M, Kleiman M, Krutauz D, Book A, Vierstra RD, Hofmann K, Reis N, Glickman MH, Pick E.

Mol Biol Cell. 2011 Apr;22(7):911-20. doi: 10.1091/mbc.E10-08-0655. Epub 2011 Feb 2.

26.

Centrosomal Chk2 in DNA damage responses and cell cycle progression.

Golan A, Pick E, Tsvetkov L, Nadler Y, Kluger H, Stern DF.

Cell Cycle. 2010 Jul 1;9(13):2647-56.

27.

A prenylated p47phox-p67phox-Rac1 chimera is a Quintessential NADPH oxidase activator: membrane association and functional capacity.

Mizrahi A, Berdichevsky Y, Casey PJ, Pick E.

J Biol Chem. 2010 Aug 13;285(33):25485-99. doi: 10.1074/jbc.M110.113779. Epub 2010 Jun 7.

28.

Editorial: When charge is in charge--"Millikan" for leukocyte biologists.

Pick E.

J Leukoc Biol. 2010 Apr;87(4):537-40. doi: 10.1189/jlb.1109710. Review. No abstract available.

PMID:
20356903
29.

PCI complexes: Beyond the proteasome, CSN, and eIF3 Troika.

Pick E, Hofmann K, Glickman MH.

Mol Cell. 2009 Aug 14;35(3):260-4. doi: 10.1016/j.molcel.2009.07.009. Review.

30.

Phosphatidylinositol-3-kinase as a therapeutic target in melanoma.

Aziz SA, Davies M, Pick E, Zito C, Jilaveanu L, Camp RL, Rimm DL, Kluger Y, Kluger HM.

Clin Cancer Res. 2009 May 1;15(9):3029-36. doi: 10.1158/1078-0432.CCR-08-2768. Epub 2009 Apr 21.

31.

In the land of the rising sun with the COP9 signalosome and related Zomes. Symposium on the COP9 signalosome, Proteasome and eIF3.

Pick E, Pintard L.

EMBO Rep. 2009 Apr;10(4):343-8. doi: 10.1038/embor.2009.27. Epub 2009 Mar 13. Review. No abstract available.

32.

Dissociation of Rac1(GDP).RhoGDI complexes by the cooperative action of anionic liposomes containing phosphatidylinositol 3,4,5-trisphosphate, Rac guanine nucleotide exchange factor, and GTP.

Ugolev Y, Berdichevsky Y, Weinbaum C, Pick E.

J Biol Chem. 2008 Aug 8;283(32):22257-71. doi: 10.1074/jbc.M800734200. Epub 2008 May 27.

33.

Cell-free assays: the reductionist approach to the study of NADPH oxidase assembly, or "all you wanted to know about cell-free assays but did not dare to ask".

Molshanski-Mor S, Mizrahi A, Ugolev Y, Dahan I, Berdichevsky Y, Pick E.

Methods Mol Biol. 2007;412:385-428. doi: 10.1007/978-1-59745-467-4_25.

PMID:
18453125
34.

Assessing expression of apoptotic markers using large cohort tissue microarrays.

Pick E, McCarthy MM, Kluger HM.

Methods Mol Biol. 2008;414:83-93. Review.

PMID:
18175814
35.

HSP90 as a marker of progression in melanoma.

McCarthy MM, Pick E, Kluger Y, Gould-Rothberg B, Lazova R, Camp RL, Rimm DL, Kluger HM.

Ann Oncol. 2008 Mar;19(3):590-4. Epub 2007 Nov 23.

PMID:
18037622
36.

Characterization of surface structure and p47phox SH3 domain-mediated conformational changes for human neutrophil flavocytochrome b.

Taylor RM, Lord CI, Riesselman MH, Gripentrog JM, Leto TL, McPhail LC, Berdichevsky Y, Pick E, Jesaitis AJ.

Biochemistry. 2007 Dec 11;46(49):14291-304. Epub 2007 Nov 16.

PMID:
18004884
38.

Mammalian DET1 regulates Cul4A activity and forms stable complexes with E2 ubiquitin-conjugating enzymes.

Pick E, Lau OS, Tsuge T, Menon S, Tong Y, Dohmae N, Plafker SM, Deng XW, Wei N.

Mol Cell Biol. 2007 Jul;27(13):4708-19. Epub 2007 Apr 23.

39.

Opening the black box: lessons from cell-free systems on the phagocyte NADPH-oxidase.

Dagher MC, Pick E.

Biochimie. 2007 Sep;89(9):1123-32. Epub 2007 Mar 12. Review.

PMID:
17434657
40.

High HSP90 expression is associated with decreased survival in breast cancer.

Pick E, Kluger Y, Giltnane JM, Moeder C, Camp RL, Rimm DL, Kluger HM.

Cancer Res. 2007 Apr 1;67(7):2932-7.

41.

Bridging the divide or deepening it?

Pick E.

Science. 2006 Jul 14;313(5784):169-70. No abstract available.

PMID:
16840677
42.
43.

Assembly of the phagocyte NADPH oxidase complex: chimeric constructs derived from the cytosolic components as tools for exploring structure-function relationships.

Mizrahi A, Berdichevsky Y, Ugolev Y, Molshanski-Mor S, Nakash Y, Dahan I, Alloul N, Gorzalczany Y, Sarfstein R, Hirshberg M, Pick E.

J Leukoc Biol. 2006 May;79(5):881-95. Review. Erratum in: J Leukoc Biol. 2006 Aug;80(2):448-9.

PMID:
16641134
44.

Activation of the phagocyte NADPH oxidase by Rac Guanine nucleotide exchange factors in conjunction with ATP and nucleoside diphosphate kinase.

Mizrahi A, Molshanski-Mor S, Weinbaum C, Zheng Y, Hirshberg M, Pick E.

J Biol Chem. 2005 Feb 4;280(5):3802-11. Epub 2004 Nov 19. Erratum in: J Biol Chem. 2005 Mar 25;280(12):12064.

45.

Placental protein 13 (PP-13): effects on cultured trophoblasts, and its detection in human body fluids in normal and pathological pregnancies.

Burger O, Pick E, Zwickel J, Klayman M, Meiri H, Slotky R, Mandel S, Rabinovitch L, Paltieli Y, Admon A, Gonen R.

Placenta. 2004 Aug;25(7):608-22.

PMID:
15193867
46.

Participation of the proteasomal lid subunit Rpn11 in mitochondrial morphology and function is mapped to a distinct C-terminal domain.

Rinaldi T, Pick E, Gambadoro A, Zilli S, Maytal-Kivity V, Frontali L, Glickman MH.

Biochem J. 2004 Jul 1;381(Pt 1):275-85.

47.

Functional analyses of placental protein 13/galectin-13.

Than NG, Pick E, Bellyei S, Szigeti A, Burger O, Berente Z, Janaky T, Boronkai A, Kliman H, Meiri H, Bohn H, Than GN, Sumegi B.

Eur J Biochem. 2004 Mar;271(6):1065-78.

PMID:
15009185
48.

Dual role of Rac in the assembly of NADPH oxidase, tethering to the membrane and activation of p67phox: a study based on mutagenesis of p67phox-Rac1 chimeras.

Sarfstein R, Gorzalczany Y, Mizrahi A, Berdichevsky Y, Molshanski-Mor S, Weinbaum C, Hirshberg M, Dagher MC, Pick E.

J Biol Chem. 2004 Apr 16;279(16):16007-16. Epub 2004 Feb 3.

49.
50.

The COP9 signalosome-like complex in S. cerevisiae and links to other PCI complexes.

Maytal-Kivity V, Pick E, Piran R, Hofmann K, Glickman MH.

Int J Biochem Cell Biol. 2003 May;35(5):706-15.

PMID:
12672462

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