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Items: 19

1.

Human liver methionine cycle: MAT1A and GNMT gene resequencing, functional genomics, and hepatic genotype-phenotype correlation.

Ji Y, Nordgren KK, Chai Y, Hebbring SJ, Jenkins GD, Abo RP, Peng Y, Pelleymounter LL, Moon I, Eckloff BW, Chai X, Zhang J, Fridley BL, Yee VC, Wieben ED, Weinshilboum RM.

Drug Metab Dispos. 2012 Oct;40(10):1984-92. doi: 10.1124/dmd.112.046953. Epub 2012 Jul 17.

2.

A novel application of pattern recognition for accurate SNP and indel discovery from high-throughput data: targeted resequencing of the glucocorticoid receptor co-chaperone FKBP5 in a Caucasian population.

Pelleymounter LL, Moon I, Johnson JA, Laederach A, Halvorsen M, Eckloff B, Abo R, Rossetti S.

Mol Genet Metab. 2011 Dec;104(4):457-69. doi: 10.1016/j.ymgme.2011.08.019. Epub 2011 Aug 24.

3.

Methionine adenosyltransferase 2A/2B and methylation: gene sequence variation and functional genomics.

Nordgren KK, Peng Y, Pelleymounter LL, Moon I, Abo R, Feng Q, Eckloff B, Yee VC, Wieben E, Weinshilboum RM.

Drug Metab Dispos. 2011 Nov;39(11):2135-47. doi: 10.1124/dmd.111.040857. Epub 2011 Aug 3.

4.

Acetaminophen-NAPQI hepatotoxicity: a cell line model system genome-wide association study.

Moyer AM, Fridley BL, Jenkins GD, Batzler AJ, Pelleymounter LL, Kalari KR, Ji Y, Chai Y, Nordgren KK, Weinshilboum RM.

Toxicol Sci. 2011 Mar;120(1):33-41. doi: 10.1093/toxsci/kfq375. Epub 2010 Dec 22.

5.

Catechol O-methyltransferase pharmacogenomics and selective serotonin reuptake inhibitor response.

Ji Y, Biernacka J, Snyder K, Drews M, Pelleymounter LL, Colby C, Wang L, Mrazek DA, Weinshilboum RM.

Pharmacogenomics J. 2012 Feb;12(1):78-85. doi: 10.1038/tpj.2010.69. Epub 2010 Sep 28.

6.

Pharmacogenetics of the mycophenolic acid targets inosine monophosphate dehydrogenases IMPDH1 and IMPDH2: gene sequence variation and functional genomics.

Wu TY, Peng Y, Pelleymounter LL, Moon I, Eckloff BW, Wieben ED, Yee VC, Weinshilboum RM.

Br J Pharmacol. 2010 Dec;161(7):1584-98. doi: 10.1111/j.1476-5381.2010.00987.x.

7.

CD38 expression, function, and gene resequencing in a human lymphoblastoid cell line-based model system.

Hartman WR, Pelleymounter LL, Moon I, Kalari K, Liu M, Wu TY, Escande C, Nin V, Chini EN, Weinshilboum RM.

Leuk Lymphoma. 2010 Jul;51(7):1315-25. doi: 10.3109/10428194.2010.483299.

8.

Functional genetic polymorphisms in the aromatase gene CYP19 vary the response of breast cancer patients to neoadjuvant therapy with aromatase inhibitors.

Wang L, Ellsworth KA, Moon I, Pelleymounter LL, Eckloff BW, Martin YN, Fridley BL, Jenkins GD, Batzler A, Suman VJ, Ravi S, Dixon JM, Miller WR, Wieben ED, Buzdar A, Weinshilboum RM, Ingle JN.

Cancer Res. 2010 Jan 1;70(1):319-28. doi: 10.1158/0008-5472.CAN-09-3224.

9.

Catechol O-methyltransferase pharmacogenomics: human liver genotype-phenotype correlation and proximal promoter studies.

Zhang J, Ji Y, Moon I, Pelleymounter LL, Ezequel Salavaggione O, Wu Y, Jenkins GD, Batzler AJ, Schaid DJ, Weinshilboum RM.

Pharmacogenet Genomics. 2009 Aug;19(8):577-87. doi: 10.1097/FPC.0b013e32832c15c6.

10.

Cytosolic 5'-nucleotidase III (NT5C3): gene sequence variation and functional genomics.

Aksoy P, Zhu MJ, Kalari KR, Moon I, Pelleymounter LL, Eckloff BW, Wieben ED, Yee VC, Weinshilboum RM, Wang L.

Pharmacogenet Genomics. 2009 Aug;19(8):567-76. doi: 10.1097/FPC.0b013e32832c14b8.

11.

Human S-adenosylhomocysteine hydrolase: common gene sequence variation and functional genomic characterization.

Feng Q, Keshtgarpour M, Pelleymounter LL, Moon I, Kalari KR, Eckloff BW, Wieben ED, Weinshilboum RM.

J Neurochem. 2009 Sep;110(6):1806-17. doi: 10.1111/j.1471-4159.2009.06276.x. Epub 2009 Jul 8.

12.

Human glucocorticoid receptor alpha gene (NR3C1) pharmacogenomics: gene resequencing and functional genomics.

Niu N, Manickam V, Kalari KR, Moon I, Pelleymounter LL, Eckloff BW, Wieben ED, Schaid DJ, Wang L.

J Clin Endocrinol Metab. 2009 Aug;94(8):3072-84. doi: 10.1210/jc.2008-2109. Epub 2009 May 12.

13.

Gemcitabine pharmacogenomics: deoxycytidine kinase and cytidylate kinase gene resequencing and functional genomics.

Kocabas NA, Aksoy P, Pelleymounter LL, Moon I, Ryu JS, Gilbert JA, Salavaggione OE, Eckloff BW, Wieben ED, Yee V, Weinshilboum RM, Ames MM.

Drug Metab Dispos. 2008 Sep;36(9):1951-9. doi: 10.1124/dmd.108.020925. Epub 2008 Jun 12.

14.

Proteasome beta subunit pharmacogenomics: gene resequencing and functional genomics.

Wang L, Kumar S, Fridley BL, Kalari KR, Moon I, Pelleymounter LL, Hildebrandt MA, Batzler A, Eckloff BW, Wieben ED, Greipp PR.

Clin Cancer Res. 2008 Jun 1;14(11):3503-13. doi: 10.1158/1078-0432.CCR-07-5150.

15.

Human betaine-homocysteine methyltransferase (BHMT) and BHMT2: common gene sequence variation and functional characterization.

Li F, Feng Q, Lee C, Wang S, Pelleymounter LL, Moon I, Eckloff BW, Wieben ED, Schaid DJ, Yee V, Weinshilboum RM.

Mol Genet Metab. 2008 Jul;94(3):326-35. doi: 10.1016/j.ymgme.2008.03.013. Epub 2008 May 23.

16.

A comprehensive examination of CYP19 variation and breast density.

Olson JE, Ma CX, Pelleymounter LL, Schaid DJ, Pankratz VS, Vierkant RA, Fredericksen ZS, Ingle JN, Wu Y, Couch F, Sellers TA, Weinshilboum RM, Vachon CM.

Cancer Epidemiol Biomarkers Prev. 2007 Mar;16(3):623-5. No abstract available.

17.

A comprehensive examination of CYP19 variation and risk of breast cancer using two haplotype-tagging approaches.

Olson JE, Ingle JN, Ma CX, Pelleymounter LL, Schaid DJ, Pankratz VS, Vierkant RA, Fredericksen ZS, Wu Y, Couch FJ, Vachon CM, Sellers TA, Weinshilboum RM.

Breast Cancer Res Treat. 2007 Apr;102(2):237-47. Epub 2006 Sep 27.

18.

Glutathione S-transferase omega 1 and omega 2 pharmacogenomics.

Mukherjee B, Salavaggione OE, Pelleymounter LL, Moon I, Eckloff BW, Schaid DJ, Wieben ED, Weinshilboum RM.

Drug Metab Dispos. 2006 Jul;34(7):1237-46. Epub 2006 Apr 25. Erratum in: Drug Metab Dispos. 2006 Sep;34(9):1666.

19.

Gemcitabine pharmacogenomics: cytidine deaminase and deoxycytidylate deaminase gene resequencing and functional genomics.

Gilbert JA, Salavaggione OE, Ji Y, Pelleymounter LL, Eckloff BW, Wieben ED, Ames MM, Weinshilboum RM.

Clin Cancer Res. 2006 Mar 15;12(6):1794-803.

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