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Causes of death in rheumatoid arthritis: How do they compare to the general population?

Widdifield J, Paterson JM, Huang A, Bernatsky S.

Arthritis Care Res (Hoboken). 2018 Mar 7. doi: 10.1002/acr.23548. [Epub ahead of print]


Risk of Hip Arthroplasty After Open Reduction Internal Fixation of a Fracture of the Acetabulum: A Matched Cohort Study.

Henry PDG, Si-Hyeong Park S, Paterson JM, Kreder HJ, Jenkinson R, Wasserstein D.

J Orthop Trauma. 2018 Mar;32(3):134-140. doi: 10.1097/BOT.0000000000001048.


Trends and uptake of new formulations of controlled-release oxycodone in Canada.

Gomes T, Jain S, Paterson JM, Sketris I, Caetano P, Henry D; Canadian Network for Observational Drug Effect Studies (CNODES) Investigators.

Pharmacoepidemiol Drug Saf. 2018 Jan 23. doi: 10.1002/pds.4390. [Epub ahead of print]


Utilization and Short-Term Outcomes of Primary Total Hip and Knee Arthroplasty in the United States and Canada: An Analysis of New York and Ontario Administrative Data.

Cram P, Landon BE, Matelski J, Ling V, Stukel TA, Paterson JM, Gandhi R, Hawker GA, Ravi B.

Arthritis Rheumatol. 2017 Dec 29. doi: 10.1002/art.40407. [Epub ahead of print]


Senior high-cost healthcare users' resource utilization and outcomes: a protocol of a retrospective matched cohort study in Canada.

Muratov S, Lee J, Holbrook A, Paterson JM, Guertin JR, Mbuagbaw L, Gomes T, Khuu W, Pequeno P, Costa AP, Tarride JE.

BMJ Open. 2017 Dec 26;7(12):e018488. doi: 10.1136/bmjopen-2017-018488.


Prior Authorization and Canadian Public Utilization of Direct-Acting Oral Anticoagulants.

Gao L, Tadrous M, Knowles S, Mamdani M, Paterson JM, Juurlink D, Gomes T.

Healthc Policy. 2017 Nov;13(2):68-78.


Association of Overlapping Surgery With Increased Risk for Complications Following Hip Surgery: A Population-Based, Matched Cohort Study.

Ravi B, Pincus D, Wasserstein D, Govindarajan A, Huang A, Austin PC, Jenkinson R, Henry PDG, Paterson JM, Kreder HJ.

JAMA Intern Med. 2018 Jan 1;178(1):75-83. doi: 10.1001/jamainternmed.2017.6835.


Association Between Wait Time and 30-Day Mortality in Adults Undergoing Hip Fracture Surgery.

Pincus D, Ravi B, Wasserstein D, Huang A, Paterson JM, Nathens AB, Kreder HJ, Jenkinson RJ, Wodchis WP.

JAMA. 2017 Nov 28;318(20):1994-2003. doi: 10.1001/jama.2017.17606.


Changes in the dispensing of opioid medications in Canada following the introduction of a tamper-deterrent formulation of long-acting oxycodone: a time series analysis.

Gomes T, Mastorakos A, Paterson JM, Sketris I, Caetano P, Greaves S, Henry D; Canadian Network for Observational Drug Effect Studies Investigators.

CMAJ Open. 2017 Nov 22;5(4):E800-E807. doi: 10.9778/cmajo.20170104.


Comparative safety of direct oral anticoagulants and warfarin in venous thromboembolism: multicentre, population based, observational study.

Jun M, Lix LM, Durand M, Dahl M, Paterson JM, Dormuth CR, Ernst P, Yao S, Renoux C, Tamim H, Wu C, Mahmud SM, Hemmelgarn BR; Canadian Network for Observational Drug Effect Studies (CNODES) Investigators.

BMJ. 2017 Oct 17;359:j4323. doi: 10.1136/bmj.j4323.


Real-world health care utilization and effectiveness of omalizumab for the treatment of severe asthma.

Tadrous M, Khuu W, Lebovic G, Stanbrook MB, Martins D, Paterson JM, Mamdani MM, Juurlink DN, Gomes T.

Ann Allergy Asthma Immunol. 2018 Jan;120(1):59-65.e2. doi: 10.1016/j.anai.2017.08.016. Epub 2017 Oct 3.


Gabapentin, opioids, and the risk of opioid-related death: A population-based nested case-control study.

Gomes T, Juurlink DN, Antoniou T, Mamdani MM, Paterson JM, van den Brink W.

PLoS Med. 2017 Oct 3;14(10):e1002396. doi: 10.1371/journal.pmed.1002396. eCollection 2017 Oct.


Prevalence and characteristics of opioid-related deaths involving alcohol in Ontario, Canada.

Gomes T, Juurlink DN, Mamdani MM, Paterson JM, van den Brink W.

Drug Alcohol Depend. 2017 Oct 1;179:416-423. doi: 10.1016/j.drugalcdep.2017.07.008. Epub 2017 Aug 5.


Outcomes of After-Hours Hip Fracture Surgery.

Pincus D, Desai SJ, Wasserstein D, Ravi B, Paterson JM, Henry P, Kreder HJ, Jenkinson R.

J Bone Joint Surg Am. 2017 Jun 7;99(11):914-922. doi: 10.2106/JBJS.16.00788.


Lipophilic β-Blockers and Suicide in the Elderly.

Zipursky JS, Macdonald EM, Luo J, Gomes T, Mamdani MM, Paterson JM, Juurlink DN; Canadian Drug Safety and Effectiveness Research Network.

J Clin Psychopharmacol. 2017 Jun;37(3):381-384. doi: 10.1097/JCP.0000000000000695. No abstract available.


Primary Care Screening and Comorbidity Management in Rheumatoid Arthritis in Ontario, Canada.

Widdifield J, Ivers NM, Bernatsky S, Jaakkimainen L, Bombardier C, Thorne JC, Ahluwalia V, Paterson JM, Young J, Wing L, Tu K.

Arthritis Care Res (Hoboken). 2017 Oct;69(10):1495-1503. doi: 10.1002/acr.23178. Epub 2017 Aug 22.


Self-Monitoring of Blood Glucose: Impact of Quantity Limits in Public Drug Formularies on Provincial Costs Across Canada.

Knowles SR, Lee K, Paterson JM, Shah BR, Mamdani MM, Juurlink DN, Gomes T.

Can J Diabetes. 2017 Apr;41(2):138-142. doi: 10.1016/j.jcjd.2016.08.225. Epub 2016 Dec 15.


High-Dose Opioid Prescribing and Opioid-Related Hospitalization: A Population-Based Study.

Fernandes K, Martins D, Juurlink D, Mamdani M, Paterson JM, Spooner L, Singh S, Gomes T.

PLoS One. 2016 Dec 14;11(12):e0167479. doi: 10.1371/journal.pone.0167479. eCollection 2016. Erratum in: PLoS One. 2017 Jan 20;12 (1):e0170834.


The Cardiovascular Safety of Dutasteride.

Skeldon SC, Macdonald EM, Law MR, Huang A, Paterson JM, Mamdani MM, Juurlink D.

J Urol. 2017 May;197(5):1309-1314. doi: 10.1016/j.juro.2016.11.082. Epub 2016 Nov 16.


Association of a Blood Glucose Test Strip Quantity-Limit Policy With Patient Outcomes: A Population-Based Study.

Gomes T, Martins D, Tadrous M, Paterson JM, Shah BR, Tu JV, Juurlink DN, Chu A, Mamdani MM.

JAMA Intern Med. 2017 Jan 1;177(1):61-66. doi: 10.1001/jamainternmed.2016.6851.


Printed educational messages fail to increase use of thiazides as first-line medication for hypertension in primary care: a cluster randomized controlled trial [ISRCTN72772651].

Zwarenstein M, Grimshaw JM, Presseau J, Francis JJ, Godin G, Johnston M, Eccles MP, Tetroe J, Shiller SK, Croxford R, Kelsall D, Paterson JM, Austin PC, Tu K, Yun L, Hux JE.

Implement Sci. 2016 Sep 17;11(1):124. doi: 10.1186/s13012-016-0486-3.


Cardiovascular Risk in Hypertension in Relation to Achieved Blood Pressure Using Automated Office Blood Pressure Measurement.

Myers MG, Kaczorowski J, Dolovich L, Tu K, Paterson JM.

Hypertension. 2016 Oct;68(4):866-72. doi: 10.1161/HYPERTENSIONAHA.116.07721. Epub 2016 Aug 15.


Association Between Incretin-Based Drugs and the Risk of Acute Pancreatitis.

Azoulay L, Filion KB, Platt RW, Dahl M, Dormuth CR, Clemens KK, Durand M, Hu N, Juurlink DN, Paterson JM, Targownik LE, Turin TC, Ernst P; and the Canadian Network for Observational Drug Effect Studies (CNODES) Investigators, Suissa S, Dormuth CR, Hemmelgarn BR, Teare GF, Caetano P, Chateau D, Henry DA, Paterson JM, LeLorier J, Levy AR, Ernst P, Platt RW, Sketris IS.

JAMA Intern Med. 2016 Oct 1;176(10):1464-1473. doi: 10.1001/jamainternmed.2016.1522.


Hospitalization Rates for Patients on Assisted Peritoneal Dialysis Compared with In-Center Hemodialysis.

Oliver MJ, Al-Jaishi AA, Dixon SN, Perl J, Jain AK, Lavoie SD, Nash DM, Paterson JM, Lok CE, Quinn RR.

Clin J Am Soc Nephrol. 2016 Sep 7;11(9):1606-14. doi: 10.2215/CJN.10130915. Epub 2016 Jul 27.


Trends in the use and cost of antipsychotics among older adults from 2007 to 2013: a repeated cross-sectional study.

Foster PD, Camacho X, Vigod S, Yao Z, Juurlink DN, Paterson JM, Mamdani MM, Martins D, Gomes T.

CMAJ Open. 2016 Jun 10;4(2):E292-7. doi: 10.9778/cmajo.20150095. eCollection 2016 Apr-Jun.


Wait times to rheumatology care for patients with rheumatic diseases: a data linkage study of primary care electronic medical records and administrative data.

Widdifield J, Bernatsky S, Thorne JC, Bombardier C, Jaakkimainen RL, Wing L, Paterson JM, Ivers N, Butt D, Lyddiatt A, Hofstetter C, Ahluwalia V, Tu K.

CMAJ Open. 2016 May 11;4(2):E205-12. doi: 10.9778/cmajo.20150116. eCollection 2016 Apr-Jun.


Self-Monitoring of Blood Glucose Levels: Evaluating the Impact of a Policy of Quantity Limits on Test-Strip Use and Costs.

Gomes T, Martins D, Tadrous M, Paterson JM, Shah BR, Juurlink DN, Singh S, Mamdani MM.

Can J Diabetes. 2016 Oct;40(5):431-435. doi: 10.1016/j.jcjd.2016.03.003. Epub 2016 May 17.


Off-label use of inhaled tobramycin in Ontario, Canada.

Tadrous M, Khuu W, Paterson JM, Mamdani MM, Juurlink DN, Gomes T.

Thorax. 2016 Sep;71(9):862-4. doi: 10.1136/thoraxjnl-2015-208145. Epub 2016 May 10.


Occurrence of pregnancy and pregnancy outcomes during isotretinoin therapy.

Henry D, Dormuth C, Winquist B, Carney G, Bugden S, Teare G, Lévesque LE, Bérard A, Paterson JM, Platt RW; CNODES (Canadian Network for Observational Drug Effect Studies) Investigators.

CMAJ. 2016 Jul 12;188(10):723-30. doi: 10.1503/cmaj.151243. Epub 2016 Apr 25.


A Multicenter Observational Study of Incretin-based Drugs and Heart Failure.

Filion KB, Azoulay L, Platt RW, Dahl M, Dormuth CR, Clemens KK, Hu N, Paterson JM, Targownik L, Turin TC, Udell JA, Ernst P; CNODES Investigators.

N Engl J Med. 2016 Mar 24;374(12):1145-54. doi: 10.1056/NEJMoa1506115.


Incretin based drugs and the risk of pancreatic cancer: international multicentre cohort study.

Azoulay L, Filion KB, Platt RW, Dahl M, Dormuth CR, Clemens KK, Durand M, Juurlink DN, Targownik LE, Turin TC, Paterson JM, Ernst P; Canadian Network for Observational Drug Effect Studies Investigators.

BMJ. 2016 Feb 17;352:i581. doi: 10.1136/bmj.i581.


The Longterm Effect of Early Intensive Treatment of Seniors with Rheumatoid Arthritis: A Comparison of 2 Population-based Cohort Studies on Time to Joint Replacement Surgery.

Widdifield J, Moura CS, Wang Y, Abrahamowicz M, Paterson JM, Huang A, Beauchamp ME, Boire G, Fortin PR, Bessette L, Bombardier C, Hanly JG, Feldman D, Bernatsky S; CAnadian Network for Advanced Interdisciplinary Methods for comparative effectiveness research (CAN-AIM).

J Rheumatol. 2016 May;43(5):861-8. doi: 10.3899/jrheum.151156. Epub 2016 Feb 15.


Trends in the coprescription of proton pump inhibitors with clopidogrel: an ecological analysis.

Juurlink DN, Gomes T, Paterson JM, Hellings C, Mamdani MM.

CMAJ Open. 2015 Nov 26;3(4):E428-31. doi: 10.9778/cmajo.20140078. eCollection 2015 Oct-Dec.


Professional Pharmacy Services and Patient Complexity: An Observational Study.

Ignacy TA, Camacho X, Mamdani MM, Juurlink DN, Paterson JM, Gomes T.

J Pharm Pharm Sci. 2015;18(5):863-70.


Retrospective analysis of trends in dispensing long-acting non-tamper-resistant oxycodone near the Canada-United States border.

Gomes T, Paterson JM, Mukati M, Henry D; Canadian Network for Observational Drug Effect Studies investigators.

CMAJ Open. 2015 Apr 2;3(2):E231-5. doi: 10.9778/cmajo.20140103. eCollection 2015 Apr-Jun.


Proton pump inhibitors and the risk of acute kidney injury in older patients: a population-based cohort study.

Antoniou T, Macdonald EM, Hollands S, Gomes T, Mamdani MM, Garg AX, Paterson JM, Juurlink DN.

CMAJ Open. 2015 Apr 2;3(2):E166-71. doi: 10.9778/cmajo.20140074. eCollection 2015 Apr-Jun.


The impact of policies to reduce blood glucose test strip utilization and costs in Canada.

Gomes T, Martins D, Cheng L, Kratzer J, Juurlink DN, Shah BR, Mamdani MM, Paterson JM, Law MR.

Can J Public Health. 2015 Apr 30;106(4):e210-6. doi: 10.17269/cjph.106.4788.


Thresholds for Diagnosing Hypertension Based on Automated Office Blood Pressure Measurements and Cardiovascular Risk.

Myers MG, Kaczorowski J, Paterson JM, Dolovich L, Tu K.

Hypertension. 2015 Sep;66(3):489-95. doi: 10.1161/HYPERTENSIONAHA.115.05782. Epub 2015 Jul 27.


Patients With Ankylosing Spondylitis Have Increased Cardiovascular and Cerebrovascular Mortality: A Population-Based Study.

Haroon NN, Paterson JM, Li P, Inman RD, Haroon N.

Ann Intern Med. 2015 Sep 15;163(6):409-16. doi: 10.7326/M14-2470.


Serotonin-Norepinephrine Reuptake Inhibitors and the Risk of AKI: A Cohort Study of Eight Administrative Databases and Meta-Analysis.

Renoux C, Lix LM, Patenaude V, Bresee LC, Paterson JM, Lafrance JP, Tamim H, Mahmud SM, Alsabbagh MW, Hemmelgarn B, Dormuth CR, Ernst P; Canadian Network of Observational Drug Effect Studies (CNODES) Investigators.

Clin J Am Soc Nephrol. 2015 Oct 7;10(10):1716-22. doi: 10.2215/CJN.11271114. Epub 2015 Jul 31.


Rates of Anomalous Bupropion Prescriptions in Ontario, Canada.

Steele LS, Macdonald EM, Gomes T, Hollands S, Paterson JM, Mamdani MM, Juurlink DN; Canadian Drug Safety and Effectiveness Research Network.

Ann Fam Med. 2015 Jul-Aug;13(4):343-6. doi: 10.1370/afm.1818.


Socioeconomic status and risk of hemorrhage during warfarin therapy for atrial fibrillation: A population-based study.

Cressman AM, Macdonald EM, Yao Z, Austin PC, Gomes T, Paterson JM, Kapral MK, Mamdani MM, Juurlink DN; Canadian Drug Safety and Effectiveness Research Network (CDSERN).

Am Heart J. 2015 Jul;170(1):133-40, 140.e1-3. doi: 10.1016/j.ahj.2015.03.014. Epub 2015 Mar 31.


A population-based study of the drug interaction between clopidogrel and angiotensin converting enzyme inhibitors.

Cressman AM, Macdonald EM, Fernandes KA, Gomes T, Paterson JM, Mamdani MM, Juurlink DN; Canadian Drug Safety Effectiveness Research Network (CDSERN).

Br J Clin Pharmacol. 2015 Oct;80(4):662-9. doi: 10.1111/bcp.12682. Epub 2015 Jul 2.


Increased risk of mycobacterial infections associated with anti-rheumatic medications.

Brode SK, Jamieson FB, Ng R, Campitelli MA, Kwong JC, Paterson JM, Li P, Marchand-Austin A, Bombardier C, Marras TK.

Thorax. 2015 Jul;70(7):677-82. doi: 10.1136/thoraxjnl-2014-206470. Epub 2015 Apr 24.


Public Drug Coverage and Its Impact on Triptan Use Across Canada: A Population-Based Study.

Amadio A, Lee K, Yao Z, Camacho X, Knowles S, Lay C, Paterson JM, Hunt J, Gomes T; Ontario Drug Policy Research Network.

Headache. 2015 Jul-Aug;55 Suppl 4:212-20. doi: 10.1111/head.12508. Epub 2015 Mar 7.


Rates of ischemic stroke during warfarin treatment for atrial fibrillation.

Tung JM, Mamdani MM, Juurlink DN, Paterson JM, Kapral MK, Gomes T.

Stroke. 2015 Apr;46(4):1120-2. doi: 10.1161/STROKEAHA.114.007852. Epub 2015 Feb 19. Erratum in: Stroke. 2015 Apr;46(4):e97.


Trends in Excess Mortality Among Patients With Rheumatoid Arthritis in Ontario, Canada.

Widdifield J, Bernatsky S, Paterson JM, Tomlinson G, Tu K, Kuriya B, Thorne JC, Pope JE, Hollands S, Bombardier C.

Arthritis Care Res (Hoboken). 2015 Aug;67(8):1047-53. doi: 10.1002/acr.22553.


Combined general and neuraxial anesthesia versus general anesthesia: a population-based cohort study.

Nash DM, Mustafa RA, McArthur E, Wijeysundera DN, Paterson JM, Sharan S, Vinden C, Wald R, Welk B, Sessler DI, Devereaux PJ, Walsh M, Garg AX.

Can J Anaesth. 2015 Apr;62(4):356-68. doi: 10.1007/s12630-015-0315-1. Epub 2015 Jan 27.


Increasing proportion of female patients with ankylosing spondylitis: a population-based study of trends in the incidence and prevalence of AS.

Haroon NN, Paterson JM, Li P, Haroon N.

BMJ Open. 2014 Dec 15;4(12):e006634. doi: 10.1136/bmjopen-2014-006634.


Impact of legislation and a prescription monitoring program on the prevalence of potentially inappropriate prescriptions for monitored drugs in Ontario: a time series analysis.

Gomes T, Juurlink D, Yao Z, Camacho X, Paterson JM, Singh S, Dhalla I, Sproule B, Mamdani M.

CMAJ Open. 2014 Oct 1;2(4):E256-61. doi: 10.9778/cmajo.20140027. eCollection 2014 Oct.

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