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Items: 26


The long noncoding RNA lncR492 inhibits neural differentiation of murine embryonic stem cells.

Winzi M, Casas Vila N, Paszkowski-Rogacz M, Ding L, Noack S, Theis M, Butter F, Buchholz F.

PLoS One. 2018 Jan 24;13(1):e0191682. doi: 10.1371/journal.pone.0191682. eCollection 2018.


lncRNA Panct1 Maintains Mouse Embryonic Stem Cell Identity by Regulating TOBF1 Recruitment to Oct-Sox Sequences in Early G1.

Chakraborty D, Paszkowski-Rogacz M, Berger N, Ding L, Mircetic J, Fu J, Iesmantavicius V, Choudhary C, Anastassiadis K, Stewart AF, Buchholz F.

Cell Rep. 2017 Dec 12;21(11):3012-3021. doi: 10.1016/j.celrep.2017.11.045.


Development of a genetic sensor that eliminates p53 deficient cells.

Mircetic J, Dietrich A, Paszkowski-Rogacz M, Krause M, Buchholz F.

Nat Commun. 2017 Nov 13;8(1):1463. doi: 10.1038/s41467-017-01688-w.


ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator.

Jahn A, Rane G, Paszkowski-Rogacz M, Sayols S, Bluhm A, Han CT, Draškovič I, Londoño-Vallejo JA, Kumar AP, Buchholz F, Butter F, Kappei D.

EMBO Rep. 2017 Jun;18(6):929-946. doi: 10.15252/embr.201744095. Epub 2017 May 12.


Phylointeractomics reconstructs functional evolution of protein binding.

Kappei D, Scheibe M, Paszkowski-Rogacz M, Bluhm A, Gossmann TI, Dietz S, Dejung M, Herlyn H, Buchholz F, Mann M, Butter F.

Nat Commun. 2017 Feb 8;8:14334. doi: 10.1038/ncomms14334.


Inactivation of Cancer Mutations Utilizing CRISPR/Cas9.

Gebler C, Lohoff T, Paszkowski-Rogacz M, Mircetic J, Chakraborty D, Camgoz A, Hamann MV, Theis M, Thiede C, Buchholz F.

J Natl Cancer Inst. 2016 Aug 30;109(1). pii: djw183. doi: 10.1093/jnci/djw183. Print 2017 Jan.


Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells.

Ding L, Paszkowski-Rogacz M, Winzi M, Chakraborty D, Theis M, Singh S, Ciotta G, Poser I, Roguev A, Chu WK, Choudhary C, Mann M, Stewart AF, Krogan N, Buchholz F.

Cell Syst. 2015 Aug 26;1(2):141-51. doi: 10.1016/j.cels.2015.08.002. Epub 2015 Aug 26.


Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity.

Karpinski J, Hauber I, Chemnitz J, Schäfer C, Paszkowski-Rogacz M, Chakraborty D, Beschorner N, Hofmann-Sieber H, Lange UC, Grundhoff A, Hackmann K, Schrock E, Abi-Ghanem J, Pisabarro MT, Surendranath V, Schambach A, Lindner C, van Lunzen J, Hauber J, Buchholz F.

Nat Biotechnol. 2016 Apr;34(4):401-9. doi: 10.1038/nbt.3467. Epub 2016 Feb 22.


RNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates fasudil as an antileukemic drug.

Wermke M, Camgoz A, Paszkowski-Rogacz M, Thieme S, von Bonin M, Dahl A, Platzbecker U, Theis M, Ehninger G, Brenner S, Bornhäuser M, Buchholz F.

Blood. 2015 Jun 11;125(24):3760-8. doi: 10.1182/blood-2014-07-590646. Epub 2015 Apr 30.


Targeting Human Long Noncoding Transcripts by Endoribonuclease-Prepared siRNAs.

Theis M, Paszkowski-Rogacz M, Weisswange I, Chakraborty D, Buchholz F.

J Biomol Screen. 2015 Sep;20(8):1018-26. doi: 10.1177/1087057115583448. Epub 2015 Apr 24.


Universal Tre (uTre) recombinase specifically targets the majority of HIV-1 isolates.

Karpinski J, Chemnitz J, Hauber I, Abi-Ghanem J, Paszkowski-Rogacz M, Surendranath V, Chakrabort D, Hackmann K, Schröck E, Pisabarro MT, Hauber J, Buchholz F.

J Int AIDS Soc. 2014 Nov 2;17(4 Suppl 3):19706. doi: 10.7448/IAS.17.4.19706. eCollection 2014.


Stage-specific binding profiles of cohesin in resting and activated B lymphocytes suggest a role for cohesin in immunoglobulin class switching and maturation.

Günal-Sadık G, Paszkowski-Rogacz M, Singaravelu K, Beyer A, Buchholz F, Jessberger R.

PLoS One. 2014 Nov 6;9(11):e111748. doi: 10.1371/journal.pone.0111748. eCollection 2014.


Another brick in the wall: RNAi Screens identify new barriers in iPSC reprogramming.

Winzi M, Paszkowski-Rogacz M, Buchholz F.

Cell Stem Cell. 2014 Aug 7;15(2):116-8. doi: 10.1016/j.stem.2014.07.008.


Multipose binding in molecular docking.

Atkovska K, Samsonov SA, Paszkowski-Rogacz M, Pisabarro MT.

Int J Mol Sci. 2014 Feb 14;15(2):2622-45. doi: 10.3390/ijms15022622.


The mammalian adult neurogenesis gene ontology (MANGO) provides a structural framework for published information on genes regulating adult hippocampal neurogenesis.

Overall RW, Paszkowski-Rogacz M, Kempermann G.

PLoS One. 2012;7(11):e48527. doi: 10.1371/journal.pone.0048527. Epub 2012 Nov 5.


Polycomb group ring finger 1 cooperates with Runx1 in regulating differentiation and self-renewal of hematopoietic cells.

Ross K, Sedello AK, Todd GP, Paszkowski-Rogacz M, Bird AW, Ding L, Grinenko T, Behrens K, Hubner N, Mann M, Waskow C, Stocking C, Buchholz F.

Blood. 2012 May 3;119(18):4152-61. doi: 10.1182/blood-2011-09-382390. Epub 2012 Mar 12.


Combined RNAi and localization for functionally dissecting long noncoding RNAs.

Chakraborty D, Kappei D, Theis M, Nitzsche A, Ding L, Paszkowski-Rogacz M, Surendranath V, Berger N, Schulz H, Saar K, Hubner N, Buchholz F.

Nat Methods. 2012 Feb 12;9(4):360-2. doi: 10.1038/nmeth.1894.


A systematic RNAi synthetic interaction screen reveals a link between p53 and snoRNP assembly.

Krastev DB, Slabicki M, Paszkowski-Rogacz M, Hubner NC, Junqueira M, Shevchenko A, Mann M, Neugebauer KM, Buchholz F.

Nat Cell Biol. 2011 Jun 5;13(7):809-18. doi: 10.1038/ncb2264.


RAD21 cooperates with pluripotency transcription factors in the maintenance of embryonic stem cell identity.

Nitzsche A, Paszkowski-Rogacz M, Matarese F, Janssen-Megens EM, Hubner NC, Schulz H, de Vries I, Ding L, Huebner N, Mann M, Stunnenberg HG, Buchholz F.

PLoS One. 2011 May 12;6(5):e19470. doi: 10.1371/journal.pone.0019470.


From RNAi screens to molecular function in embryonic stem cells.

Ding L, Poser I, Paszkowski-Rogacz M, Buchholz F.

Stem Cell Rev. 2012 Mar;8(1):32-42. doi: 10.1007/s12015-011-9269-z. Review.


A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia.

Słabicki M, Theis M, Krastev DB, Samsonov S, Mundwiller E, Junqueira M, Paszkowski-Rogacz M, Teyra J, Heninger AK, Poser I, Prieur F, Truchetto J, Confavreux C, Marelli C, Durr A, Camdessanche JP, Brice A, Shevchenko A, Pisabarro MT, Stevanin G, Buchholz F.

PLoS Biol. 2010 Jun 29;8(6):e1000408. doi: 10.1371/journal.pbio.1000408.


PhenoFam-gene set enrichment analysis through protein structural information.

Paszkowski-Rogacz M, Slabicki M, Pisabarro MT, Buchholz F.

BMC Bioinformatics. 2010 May 17;11:254. doi: 10.1186/1471-2105-11-254.


SKAnking with Ska3: essential role of Ska3 in cell division revealed by combined phenotypic profiling.

Theis M, Paszkowski-Rogacz M, Buchholz F.

Cell Cycle. 2009 Nov 1;8(21):3435-7. Epub 2009 Nov 16. No abstract available.


Comparative profiling identifies C13orf3 as a component of the Ska complex required for mammalian cell division.

Theis M, Slabicki M, Junqueira M, Paszkowski-Rogacz M, Sontheimer J, Kittler R, Heninger AK, Glatter T, Kruusmaa K, Poser I, Hyman AA, Pisabarro MT, Gstaiger M, Aebersold R, Shevchenko A, Buchholz F.

EMBO J. 2009 May 20;28(10):1453-65. doi: 10.1038/emboj.2009.114. Epub 2009 Apr 23.


A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity.

Ding L, Paszkowski-Rogacz M, Nitzsche A, Slabicki MM, Heninger AK, de Vries I, Kittler R, Junqueira M, Shevchenko A, Schulz H, Hubner N, Doss MX, Sachinidis A, Hescheler J, Iacone R, Anastassiadis K, Stewart AF, Pisabarro MT, Caldarelli A, Poser I, Theis M, Buchholz F.

Cell Stem Cell. 2009 May 8;4(5):403-15. doi: 10.1016/j.stem.2009.03.009. Epub 2009 Apr 2.


SCOWLP classification: structural comparison and analysis of protein binding regions.

Teyra J, Paszkowski-Rogacz M, Anders G, Pisabarro MT.

BMC Bioinformatics. 2008 Jan 8;9:9. doi: 10.1186/1471-2105-9-9.

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