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Items: 12

1.

Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptake.

Niemi M, Pasanen MK, Neuvonen PJ.

Pharmacol Rev. 2011 Mar;63(1):157-81. doi: 10.1124/pr.110.002857. Epub 2011 Jan 18. Review.

2.

Different effects of the ABCG2 c.421C>A SNP on the pharmacokinetics of fluvastatin, pravastatin and simvastatin.

Keskitalo JE, Pasanen MK, Neuvonen PJ, Niemi M.

Pharmacogenomics. 2009 Oct;10(10):1617-24. doi: 10.2217/pgs.09.85.

PMID:
19842935
3.

Effect of SLCO1B1 polymorphism on the plasma concentrations of bile acids and bile acid synthesis marker in humans.

Xiang X, Han Y, Neuvonen M, Pasanen MK, Kalliokoski A, Backman JT, Laitila J, Neuvonen PJ, Niemi M.

Pharmacogenet Genomics. 2009 Jun;19(6):447-57. doi: 10.1097/FPC.0b013e32832bcf7b.

PMID:
19387419
4.

Polymorphism of the hepatic influx transporter organic anion transporting polypeptide 1B1 is associated with increased cholesterol synthesis rate.

Pasanen MK, Miettinen TA, Gylling H, Neuvonen PJ, Niemi M.

Pharmacogenet Genomics. 2008 Oct;18(10):921-6. doi: 10.1097/FPC.0b013e32830c1b5f.

PMID:
18794729
5.

Global analysis of genetic variation in SLCO1B1.

Pasanen MK, Neuvonen PJ, Niemi M.

Pharmacogenomics. 2008 Jan;9(1):19-33.

PMID:
18154446
6.

Different effects of SLCO1B1 polymorphism on the pharmacokinetics of atorvastatin and rosuvastatin.

Pasanen MK, Fredrikson H, Neuvonen PJ, Niemi M.

Clin Pharmacol Ther. 2007 Dec;82(6):726-33. Epub 2007 May 2.

PMID:
17473846
7.

SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid.

Pasanen MK, Neuvonen M, Neuvonen PJ, Niemi M.

Pharmacogenet Genomics. 2006 Dec;16(12):873-9.

PMID:
17108811
8.

Association of genetic polymorphism in ABCC2 with hepatic multidrug resistance-associated protein 2 expression and pravastatin pharmacokinetics.

Niemi M, Arnold KA, Backman JT, Pasanen MK, Gödtel-Armbrust U, Wojnowski L, Zanger UM, Neuvonen PJ, Eichelbaum M, Kivistö KT, Lang T.

Pharmacogenet Genomics. 2006 Nov;16(11):801-8.

PMID:
17047488
9.

SLCO1B1 polymorphism and sex affect the pharmacokinetics of pravastatin but not fluvastatin.

Niemi M, Pasanen MK, Neuvonen PJ.

Clin Pharmacol Ther. 2006 Oct;80(4):356-66.

PMID:
17015053
10.

Itraconazole, gemfibrozil and their combination markedly raise the plasma concentrations of loperamide.

Niemi M, Tornio A, Pasanen MK, Fredrikson H, Neuvonen PJ, Backman JT.

Eur J Clin Pharmacol. 2006 Jun;62(6):463-72. Epub 2006 Apr 27.

PMID:
16758263
11.

Frequencies of single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide 1B1 SLCO1B1 gene in a Finnish population.

Pasanen MK, Backman JT, Neuvonen PJ, Niemi M.

Eur J Clin Pharmacol. 2006 Jun;62(6):409-15. Epub 2006 Apr 21.

PMID:
16758257
12.

Comparison of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) as inhibitors of cytochrome P450 2C8.

Tornio A, Pasanen MK, Laitila J, Neuvonen PJ, Backman JT.

Basic Clin Pharmacol Toxicol. 2005 Aug;97(2):104-8.

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