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Items: 1 to 50 of 131

1.

What is the Minimal Clinically Important Difference for 3He MRI Ventilation Defects?

Eddy RL, Svenningsen S, McCormack DG, Parraga G.

Eur Respir J. 2018 Apr 12. pii: 1800324. doi: 10.1183/13993003.00324-2018. [Epub ahead of print] No abstract available.

PMID:
29650564
2.

Predictive value for cardiovascular events of common carotid intima media thickness and its rate of change in individuals at high cardiovascular risk - Results from the PROG-IMT collaboration.

Lorenz MW, Gao L, Ziegelbauer K, Norata GD, Empana JP, Schmidtmann I, Lin HJ, McLachlan S, Bokemark L, Ronkainen K, Amato M, Schminke U, Srinivasan SR, Lind L, Okazaki S, Stehouwer CDA, Willeit P, Polak JF, Steinmetz H, Sander D, Poppert H, Desvarieux M, Ikram MA, Johnsen SH, Staub D, Sirtori CR, Iglseder B, Beloqui O, Engström G, Friera A, Rozza F, Xie W, Parraga G, Grigore L, Plichart M, Blankenberg S, Su TC, Schmidt C, Tuomainen TP, Veglia F, Völzke H, Nijpels G, Willeit J, Sacco RL, Franco OH, Uthoff H, Hedblad B, Suarez C, Izzo R, Zhao D, Wannarong T, Catapano A, Ducimetiere P, Espinola-Klein C, Chien KL, Price JF, Bergström G, Kauhanen J, Tremoli E, Dörr M, Berenson G, Kitagawa K, Dekker JM, Kiechl S, Sitzer M, Bickel H, Rundek T, Hofman A, Mathiesen EB, Castelnuovo S, Landecho MF, Rosvall M, Gabriel R, de Luca N, Liu J, Baldassarre D, Kavousi M, de Groot E, Bots ML, Yanez DN, Thompson SG; PROG-IMT study group.

PLoS One. 2018 Apr 12;13(4):e0191172. doi: 10.1371/journal.pone.0191172. eCollection 2018.

3.

Oscillometry and Pulmonary MRI Measurements of Ventilation Heterogeneity in Obstructive Lung Disease: Relationship to Quality of Life and Disease Control.

Young HM, Guo F, Eddy RL, Maksym G, Parraga G.

J Appl Physiol (1985). 2018 Mar 15. doi: 10.1152/japplphysiol.01031.2017. [Epub ahead of print]

PMID:
29543132
4.

Free-breathing Pulmonary MR Imaging to Quantify Regional Ventilation.

Capaldi DPI, Eddy RL, Svenningsen S, Guo F, Baxter JSH, McLeod AJ, Nair P, McCormack DG, Parraga G; Canadian Respiratory Research Network.

Radiology. 2018 May;287(2):693-704. doi: 10.1148/radiol.2018171993. Epub 2018 Feb 22.

PMID:
29470939
5.

Effect of wine on carotid atherosclerosis in type 2 diabetes: a 2-year randomized controlled trial.

Golan R, Shai I, Gepner Y, Harman-Boehm I, Schwarzfuchs D, Spence JD, Parraga G, Buchanan D, Witkow S, Friger M, Liberty IF, Sarusi B, Ben-Avraham S, Sefarty D, Bril N, Rein M, Cohen N, Ceglarek U, Thiery J, Stumvoll M, Blüher M, Stampfer MJ, Rudich A, Henkin Y.

Eur J Clin Nutr. 2018 Jan 29. doi: 10.1038/s41430-018-0091-4. [Epub ahead of print]

PMID:
29379143
6.

Sputum Eosinophilia and Magnetic Resonance Imaging Ventilation Heterogeneity in Severe Asthma.

Svenningsen S, Eddy RL, Lim HF, Cox PG, Nair P, Parraga G.

Am J Respir Crit Care Med. 2018 Apr 1;197(7):876-884. doi: 10.1164/rccm.201709-1948OC.

PMID:
29313707
7.

On the Potential Role of MRI Biomarkers of COPD to Guide Bronchoscopic Lung Volume Reduction.

Adams CJ, Capaldi DPI, Di Cesare R, McCormack DG, Parraga G; Canadian Respiratory Research Network.

Acad Radiol. 2018 Feb;25(2):159-168. doi: 10.1016/j.acra.2017.08.010. Epub 2017 Oct 16.

PMID:
29051040
8.

MRI and CT lung biomarkers: Towards an in vivo understanding of lung biomechanics.

Young HM, Eddy RL, Parraga G.

Clin Biomech (Bristol, Avon). 2017 Sep 29. pii: S0268-0033(17)30210-3. doi: 10.1016/j.clinbiomech.2017.09.016. [Epub ahead of print] Review.

PMID:
29037603
9.

Through the Looking Glass and What Was Found There: Imaging Biomarkers of Chronic Obstructive Pulmonary Disease.

Capaldi DPI, Parraga G.

Am J Respir Crit Care Med. 2017 Dec 1;196(11):1364-1366. doi: 10.1164/rccm.201707-1473ED. No abstract available.

PMID:
28813162
10.

Sensitive three-dimensional ultrasound assessment of carotid atherosclerosis by weighted average of local vessel wall and plaque thickness change.

Cheng J, Ukwatta E, Shavakh S, Chow TWS, Parraga G, Spence JD, Chiu B.

Med Phys. 2017 Oct;44(10):5280-5292. doi: 10.1002/mp.12507. Epub 2017 Aug 31.

PMID:
28782187
11.

Pulmonary 3He Magnetic Resonance Imaging Biomarkers of Regional Airspace Enlargement in Alpha-1 Antitrypsin Deficiency.

Lessard E, Young HM, Bhalla A, Pike D, Sheikh K, McCormack DG, Ouriadov A, Parraga G.

Acad Radiol. 2017 Nov;24(11):1402-1411. doi: 10.1016/j.acra.2017.05.008. Epub 2017 Jun 20.

PMID:
28645458
12.

Free-breathing Functional Pulmonary MRI: Response to Bronchodilator and Bronchoprovocation in Severe Asthma.

Capaldi DPI, Sheikh K, Eddy RL, Guo F, Svenningsen S, Nair P, McCormack DG, Parraga G; Canadian Respiratory Research Network.

Acad Radiol. 2017 Oct;24(10):1268-1276. doi: 10.1016/j.acra.2017.04.012. Epub 2017 May 24.

PMID:
28551402
13.

Mild chronic obstructive pulmonary disease: why spirometry is not sufficient!

Elbehairy AF, Parraga G, Webb KA, Neder JA, O'Donnell DE; Canadian Respiratory Research Network (CRRN).

Expert Rev Respir Med. 2017 Jul;11(7):549-563. doi: 10.1080/17476348.2017.1334553. Epub 2017 Jun 5.

PMID:
28548545
14.

A pilot randomised clinical trial of mepolizumab in COPD with eosinophilic bronchitis.

Dasgupta A, Kjarsgaard M, Capaldi D, Radford K, Aleman F, Boylan C, Altman LC, Wight TN, Parraga G, O'Byrne PM, Nair P.

Eur Respir J. 2017 Mar 15;49(3). pii: 1602486. doi: 10.1183/13993003.02486-2016. Print 2017 Mar. No abstract available.

PMID:
28298405
15.

MRI ventilation abnormalities predict quality-of-life and lung function changes in mild-to-moderate COPD: longitudinal TINCan study.

Kirby M, Eddy RL, Pike D, Svenningsen S, Coxson HO, Sin DD, McCormack DG, Parraga G; Canadian Respiratory Research Network.

Thorax. 2017 May;72(5):475-477. doi: 10.1136/thoraxjnl-2016-209770. Epub 2017 Mar 3.

PMID:
28258250
16.

Thoracic CT-MRI coregistration for regional pulmonary structure-function measurements of obstructive lung disease.

Guo F, Svenningsen S, Kirby M, Capaldi DP, Sheikh K, Fenster A, Parraga G.

Med Phys. 2017 May;44(5):1718-1733. doi: 10.1002/mp.12160. Epub 2017 Apr 11.

PMID:
28206676
17.

Pulmonary MRI morphometry modeling of airspace enlargement in chronic obstructive pulmonary disease and alpha-1 antitrypsin deficiency.

Ouriadov A, Lessard E, Sheikh K, Parraga G; Canadian Respiratory Research Network.

Magn Reson Med. 2018 Jan;79(1):439-448. doi: 10.1002/mrm.26642. Epub 2017 Feb 15.

PMID:
28198571
18.
19.

Three-dimensional ultrasound measurements of carotid vessel wall and plaque thickness and their relationship with pulmonary abnormalities in ex-smokers without airflow limitation.

Cheng J, Pike D, Chow TW, Kirby M, Parraga G, Chiu B.

Int J Cardiovasc Imaging. 2016 Sep;32(9):1391-1402. Epub 2016 Jun 24.

PMID:
27342610
20.

Ultrashort echo time MRI biomarkers of asthma.

Sheikh K, Guo F, Capaldi DP, Ouriadov A, Eddy RL, Svenningsen S, Parraga G; Canadian Respiratory Research Network.

J Magn Reson Imaging. 2017 Apr;45(4):1204-1215. doi: 10.1002/jmri.25503. Epub 2016 Oct 12.

PMID:
27731948
21.

Noncystic Fibrosis Bronchiectasis: Regional Abnormalities and Response to Airway Clearance Therapy Using Pulmonary Functional Magnetic Resonance Imaging.

Svenningsen S, Guo F, McCormack DG, Parraga G.

Acad Radiol. 2017 Jan;24(1):4-12. doi: 10.1016/j.acra.2016.08.021. Epub 2016 Oct 4.

PMID:
27717759
22.

Why Is Your Patient Still Short of Breath? Understanding the Complex Pathophysiology of Dyspnea in Chronic Kidney Disease.

Salerno FR, Parraga G, McIntyre CW.

Semin Dial. 2017 Jan;30(1):50-57. doi: 10.1111/sdi.12548. Epub 2016 Sep 28. Review.

PMID:
27680887
23.

Management of COPD: Is there a role for quantitative imaging?

Kirby M, van Beek EJR, Seo JB, Biederer J, Nakano Y, Coxson HO, Parraga G.

Eur J Radiol. 2017 Jan;86:335-342. doi: 10.1016/j.ejrad.2016.08.022. Epub 2016 Aug 28. Review.

PMID:
27592252
24.

Anatomical pulmonary magnetic resonance imaging segmentation for regional structure-function measurements of asthma.

Guo F, Svenningsen S, Eddy RL, Capaldi DPI, Sheikh K, Fenster A, Parraga G.

Med Phys. 2016 Jun;43(6):2911-2926. doi: 10.1118/1.4948999.

PMID:
27277040
25.

Is ventilation heterogeneity related to asthma control?

Svenningsen S, Nair P, Guo F, McCormack DG, Parraga G.

Eur Respir J. 2016 Aug;48(2):370-9. doi: 10.1183/13993003.00393-2016. Epub 2016 May 12.

26.

Imaging how and where we breathe oxygen: another Big Short?

Capaldi DP, Guo F, Parraga G.

J Thorac Dis. 2016 Mar;8(3):E204-7. doi: 10.21037/jtd.2016.01.83. No abstract available.

27.

Hyperpolarized 3He magnetic resonance imaging ventilation defects in asthma: relationship to airway mechanics.

Leary D, Svenningsen S, Guo F, Bhatawadekar S, Parraga G, Maksym GN.

Physiol Rep. 2016 Apr;4(7). pii: e12761. doi: 10.14814/phy2.12761.

28.

Imaging Biomarkers in Lymphangioleiomyomatosis Clinical Trials. A Wolf in Sheep's Clothing?

Washko GR, Parraga G.

Ann Am Thorac Soc. 2016 Mar;13(3):307-8. doi: 10.1513/AnnalsATS.201512-818ED. No abstract available.

PMID:
26963351
29.

Regional Heterogeneity of Chronic Obstructive Pulmonary Disease Phenotypes: Pulmonary (3)He Magnetic Resonance Imaging and Computed Tomography.

Pike D, Kirby M, Eddy RL, Guo F, Capaldi DP, Ouriadov A, McCormack DG, Parraga G.

COPD. 2016 Oct;13(5):601-9. doi: 10.3109/15412555.2015.1123682. Epub 2016 Jan 20.

PMID:
26788765
30.

Ventilation Heterogeneity in Never-smokers and COPD:: Comparison of Pulmonary Functional Magnetic Resonance Imaging with the Poorly Communicating Fraction Derived From Plethysmography.

Davis C, Sheikh K, Pike D, Svenningsen S, McCormack DG, O'Donnell D, Neder JA, Parraga G; Canadian Respiratory Research Network.

Acad Radiol. 2016 Apr;23(4):398-405. doi: 10.1016/j.acra.2015.10.022. Epub 2016 Jan 8.

PMID:
26774739
31.

Pulmonary Imaging Biomarkers of Gas Trapping and Emphysema in COPD: (3)He MR Imaging and CT Parametric Response Maps.

Capaldi DP, Zha N, Guo F, Pike D, McCormack DG, Kirby M, Parraga G.

Radiology. 2016 May;279(2):597-608. doi: 10.1148/radiol.2015151484. Epub 2016 Jan 8.

PMID:
26744928
32.

Three-Dimensional Ultrasound of Carotid Plaque.

Spence JD, Parraga G.

Neuroimaging Clin N Am. 2016 Feb;26(1):69-80. doi: 10.1016/j.nic.2015.09.006. Review.

PMID:
26610661
33.

Pulmonary Artery Abnormalities in Ex-smokers with and without Airflow Obstruction.

Lindenmaier TJ, Kirby M, Paulin G, Mielniczuk L, Cunningham IA, Mura M, Licskai C, Parraga G.

COPD. 2016;13(2):224-34. doi: 10.3109/15412555.2015.1074666. Epub 2015 Nov 25.

PMID:
26606693
34.

Second-order Texture Measurements of (3)He Ventilation MRI: Proof-of-concept Evaluation of Asthma Bronchodilator Response.

Zha N, Pike D, Svenningsen S, Capaldi DP, McCormack DG, Parraga G.

Acad Radiol. 2016 Feb;23(2):176-85. doi: 10.1016/j.acra.2015.10.010. Epub 2015 Nov 18.

PMID:
26601971
35.

Noninvasive quantification of alveolar morphometry in elderly never- and ex-smokers.

Paulin GA, Ouriadov A, Lessard E, Sheikh K, McCormack DG, Parraga G.

Physiol Rep. 2015 Oct;3(10). pii: e12583. doi: 10.14814/phy2.12583.

36.

Oscillatory Positive Expiratory Pressure in Chronic Obstructive Pulmonary Disease.

Svenningsen S, Paulin GA, Sheikh K, Guo F, Hasany A, Kirby M, Rezai RE, McCormack DG, Parraga G.

COPD. 2016;13(1):66-74. doi: 10.3109/15412555.2015.1043523. Epub 2015 Oct 2.

PMID:
26430763
37.

This is what COPD looks like.

Sheikh K, Coxson HO, Parraga G.

Respirology. 2016 Feb;21(2):224-36. doi: 10.1111/resp.12611. Epub 2015 Aug 26. Review.

38.

Pulmonary CT and MRI phenotypes that help explain chronic pulmonary obstruction disease pathophysiology and outcomes.

Hoffman EA, Lynch DA, Barr RG, van Beek EJ, Parraga G; IWPFI Investigators.

J Magn Reson Imaging. 2016 Mar;43(3):544-57. doi: 10.1002/jmri.25010. Epub 2015 Jul 22. Review.

39.

Early stage radiation-induced lung injury detected using hyperpolarized (129) Xe Morphometry: Proof-of-concept demonstration in a rat model.

Ouriadov A, Fox M, Hegarty E, Parraga G, Wong E, Santyr GE.

Magn Reson Med. 2016 Jun;75(6):2421-31. doi: 10.1002/mrm.25825. Epub 2015 Jul 8.

PMID:
26154889
40.

COPD: Do Imaging Measurements of Emphysema and Airway Disease Explain Symptoms and Exercise Capacity?

Kirby M, Pike D, Sin DD, Coxson HO, McCormack DG, Parraga G.

Radiology. 2015 Dec;277(3):872-80. doi: 10.1148/radiol.2015150037. Epub 2015 Jul 7.

PMID:
26151081
41.

Ventilation heterogeneity in ex-smokers without airflow limitation.

Pike D, Kirby M, Guo F, McCormack DG, Parraga G.

Acad Radiol. 2015 Aug;22(8):1068-78. doi: 10.1016/j.acra.2015.04.006. Epub 2015 May 23.

PMID:
26008133
42.

Globally optimal co-segmentation of three-dimensional pulmonary ¹H and hyperpolarized ³He MRI with spatial consistence prior.

Guo F, Yuan J, Rajchl M, Svenningsen S, Capaldi DP, Sheikh K, Fenster A, Parraga G.

Med Image Anal. 2015 Jul;23(1):43-55. doi: 10.1016/j.media.2015.04.001. Epub 2015 Apr 17.

PMID:
25958028
43.

Pulmonary imaging abnormalities in an adult case of congenital lobar emphysema.

Pike D, Mohan S, Ma W, Lewis JF, Parraga G.

J Radiol Case Rep. 2015 Feb 28;9(2):9-15. doi: 10.3941/jrcr.v9i2.2048. eCollection 2015 Feb.

44.

Magnetic resonance imaging biomarkers of chronic obstructive pulmonary disease prior to radiation therapy for non-small cell lung cancer.

Sheikh K, Capaldi DP, Hoover DA, Palma DA, Yaremko BP, Parraga G.

Eur J Radiol Open. 2015 May 26;2:81-9. doi: 10.1016/j.ejro.2015.05.003. eCollection 2015.

45.

Functional lung avoidance for individualized radiotherapy (FLAIR): study protocol for a randomized, double-blind clinical trial.

Hoover DA, Capaldi DP, Sheikh K, Palma DA, Rodrigues GB, Dar AR, Yu E, Dingle B, Landis M, Kocha W, Sanatani M, Vincent M, Younus J, Kuruvilla S, Gaede S, Parraga G, Yaremko BP.

BMC Cancer. 2014 Dec 11;14:934. doi: 10.1186/1471-2407-14-934.

46.

Free-breathing pulmonary 1H and Hyperpolarized 3He MRI: comparison in COPD and bronchiectasis.

Capaldi DP, Sheikh K, Guo F, Svenningsen S, Etemad-Rezai R, Coxson HO, Leipsic JA, McCormack DG, Parraga G.

Acad Radiol. 2015 Mar;22(3):320-9. doi: 10.1016/j.acra.2014.10.003. Epub 2014 Dec 6.

PMID:
25491735
47.

Pulmonary hyperpolarized (129) Xe morphometry for mapping xenon gas concentrations and alveolar oxygen partial pressure: Proof-of-concept demonstration in healthy and COPD subjects.

Ouriadov A, Farag A, Kirby M, McCormack DG, Parraga G, Santyr GE.

Magn Reson Med. 2015 Dec;74(6):1726-32. doi: 10.1002/mrm.25550. Epub 2014 Dec 5.

PMID:
25483611
48.

Hyperpolarized 3He and 129Xe magnetic resonance imaging apparent diffusion coefficients: physiological relevance in older never- and ex-smokers.

Kirby M, Ouriadov A, Svenningsen S, Owrangi A, Wheatley A, Etemad-Rezai R, Santyr GE, McCormack DG, Parraga G.

Physiol Rep. 2014 Jul 16;2(7). pii: e12068. doi: 10.14814/phy2.12068.

49.

Pulmonary functional magnetic resonance imaging: asthma temporal-spatial maps.

Svenningsen S, Guo F, Kirby M, Choy S, Wheatley A, McCormack DG, Parraga G.

Acad Radiol. 2014 Nov;21(11):1402-10. doi: 10.1016/j.acra.2014.08.002.

PMID:
25300720
50.

Longitudinal Computed Tomography and Magnetic Resonance Imaging of COPD: Thoracic Imaging Network of Canada (TINCan) Study Objectives.

Kirby M, Pike D, McCormack DG, Lam S, Coxson HO, Parraga G.

Chronic Obstr Pulm Dis. 2014 Sep 25;1(2):200-211. doi: 10.15326/jcopdf.1.2.2014.0136.

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