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Items: 1 to 50 of 118

1.

Mussel-inspired 3D fiber scaffolds for heart-on-a-chip toxicity studies of engineered nanomaterials.

Ahn S, Ardoña HAM, Lind JU, Eweje F, Kim SL, Gonzalez GM, Liu Q, Zimmerman JF, Pyrgiotakis G, Zhang Z, Beltran-Huarac J, Carpinone P, Moudgil BM, Demokritou P, Parker KK.

Anal Bioanal Chem. 2018 May 10. doi: 10.1007/s00216-018-1106-7. [Epub ahead of print]

PMID:
29744562
2.

Traction force microscopy of engineered cardiac tissues.

Pasqualini FS, Agarwal A, O'Connor BB, Liu Q, Sheehy SP, Parker KK.

PLoS One. 2018 Mar 28;13(3):e0194706. doi: 10.1371/journal.pone.0194706. eCollection 2018.

3.

Production-scale fibronectin nanofibers promote wound closure and tissue repair in a dermal mouse model.

Chantre CO, Campbell PH, Golecki HM, Buganza AT, Capulli AK, Deravi LF, Dauth S, Sheehy SP, Paten JA, Gledhill K, Doucet YS, Abaci HE, Ahn S, Pope BD, Ruberti JW, Hoerstrup SP, Christiano AM, Parker KK.

Biomaterials. 2018 Jun;166:96-108. doi: 10.1016/j.biomaterials.2018.03.006. Epub 2018 Mar 5.

PMID:
29549768
4.

Formation of Multi-Component Extracellular Matrix Protein Fibers.

Ahn S, Lee KY, Parker KK, Shin K.

Sci Rep. 2018 Jan 30;8(1):1913. doi: 10.1038/s41598-018-20371-8.

5.

Soy Protein/Cellulose Nanofiber Scaffolds Mimicking Skin Extracellular Matrix for Enhanced Wound Healing.

Ahn S, Chantre CO, Gannon AR, Lind JU, Campbell PH, Grevesse T, O'Connor BB, Parker KK.

Adv Healthc Mater. 2018 May;7(9):e1701175. doi: 10.1002/adhm.201701175. Epub 2018 Jan 23.

PMID:
29359866
6.

Automated fabrication of photopatterned gelatin hydrogels for organ-on-chips applications.

Nawroth JC, Scudder LL, Halvorson RT, Tresback J, Ferrier JP, Sheehy SP, Cho A, Kannan S, Sunyovszki I, Goss JA, Campbell PH, Parker KK.

Biofabrication. 2018 Jan 16;10(2):025004. doi: 10.1088/1758-5090/aa96de.

PMID:
29337695
7.

Cardiac microphysiological devices with flexible thin-film sensors for higher-throughput drug screening.

Lind JU, Yadid M, Perkins I, O'Connor BB, Eweje F, Chantre CO, Hemphill MA, Yuan H, Campbell PH, Vlassak JJ, Parker KK.

Lab Chip. 2017 Oct 25;17(21):3692-3703. doi: 10.1039/c7lc00740j.

8.

Comparative analysis of poly-glycolic acid-based hybrid polymer starter matrices for in vitro tissue engineering.

Generali M, Kehl D, Capulli AK, Parker KK, Hoerstrup SP, Weber B.

Colloids Surf B Biointerfaces. 2017 Oct 1;158:203-212. doi: 10.1016/j.colsurfb.2017.06.046. Epub 2017 Jul 1.

PMID:
28697435
9.

Fabrication of Millimeter-Long Carbon Tubular Nanostructures Using the Self-Rolling Process Inherent in Elastic Protein Layers.

Ko H, Deravi LF, Park SJ, Jang J, Lee T, Kang C, Lee JS, Parker KK, Shin K.

Adv Mater. 2017 Aug;29(31). doi: 10.1002/adma.201701732. Epub 2017 Jun 19.

PMID:
28627043
10.

Organs-on-Chips with combined multi-electrode array and transepithelial electrical resistance measurement capabilities.

Maoz BM, Herland A, Henry OYF, Leineweber WD, Yadid M, Doyle J, Mannix R, Kujala VJ, FitzGerald EA, Parker KK, Ingber DE.

Lab Chip. 2017 Jun 27;17(13):2294-2302. doi: 10.1039/c7lc00412e.

PMID:
28608907
11.

JetValve: Rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement.

Capulli AK, Emmert MY, Pasqualini FS, Kehl D, Caliskan E, Lind JU, Sheehy SP, Park SJ, Ahn S, Weber B, Goss JA, Hoerstrup SP, Parker KK.

Biomaterials. 2017 Jul;133:229-241. doi: 10.1016/j.biomaterials.2017.04.033. Epub 2017 Apr 18.

PMID:
28445803
12.

Toward improved myocardial maturity in an organ-on-chip platform with immature cardiac myocytes.

Sheehy SP, Grosberg A, Qin P, Behm DJ, Ferrier JP, Eagleson MA, Nesmith AP, Krull D, Falls JG, Campbell PH, McCain ML, Willette RN, Hu E, Parker KK.

Exp Biol Med (Maywood). 2017 Nov;242(17):1643-1656. doi: 10.1177/1535370217701006. Epub 2017 Mar 26.

PMID:
28343439
13.

Safety and efficacy of cardiopoietic stem cells in the treatment of post-infarction left-ventricular dysfunction - From cardioprotection to functional repair in a translational pig infarction model.

Emmert MY, Wolint P, Jakab A, Sheehy SP, Pasqualini FS, Nguyen TD, Hilbe M, Seifert B, Weber B, Brokopp CE, Macejovska D, Caliskan E, von Eckardstein A, Schwartlander R, Vogel V, Falk V, Parker KK, Gyöngyösi M, Hoerstrup SP.

Biomaterials. 2017 Apr;122:48-62. doi: 10.1016/j.biomaterials.2016.11.029. Epub 2016 Nov 23.

PMID:
28107664
14.

Mechanotransduction and Metabolism in Cardiomyocyte Microdomains.

Pasqualini FS, Nesmith AP, Horton RE, Sheehy SP, Parker KK.

Biomed Res Int. 2016;2016:4081638. doi: 10.1155/2016/4081638. Epub 2016 Dec 4. Review.

15.

Neurons derived from different brain regions are inherently different in vitro: a novel multiregional brain-on-a-chip.

Dauth S, Maoz BM, Sheehy SP, Hemphill MA, Murty T, Macedonia MK, Greer AM, Budnik B, Parker KK.

J Neurophysiol. 2017 Mar 1;117(3):1320-1341. doi: 10.1152/jn.00575.2016. Epub 2016 Dec 28.

16.

Matched-Comparative Modeling of Normal and Diseased Human Airway Responses Using a Microengineered Breathing Lung Chip.

Benam KH, Novak R, Nawroth J, Hirano-Kobayashi M, Ferrante TC, Choe Y, Prantil-Baun R, Weaver JC, Bahinski A, Parker KK, Ingber DE.

Cell Syst. 2016 Nov 23;3(5):456-466.e4. doi: 10.1016/j.cels.2016.10.003. Epub 2016 Oct 27.

17.

Instrumented cardiac microphysiological devices via multimaterial three-dimensional printing.

Lind JU, Busbee TA, Valentine AD, Pasqualini FS, Yuan H, Yadid M, Park SJ, Kotikian A, Nesmith AP, Campbell PH, Vlassak JJ, Lewis JA, Parker KK.

Nat Mater. 2017 Mar;16(3):303-308. doi: 10.1038/nmat4782. Epub 2016 Oct 24.

18.

Organ Chips: Quality Assurance Systems in Regenerative Medicine.

Pasqualini FS, Emmert MY, Parker KK, Hoerstrup SP.

Clin Pharmacol Ther. 2017 Jan;101(1):31-34. doi: 10.1002/cpt.527. Epub 2016 Nov 21.

19.

A human in vitro model of Duchenne muscular dystrophy muscle formation and contractility.

Nesmith AP, Wagner MA, Pasqualini FS, O'Connor BB, Pincus MJ, August PR, Parker KK.

J Cell Biol. 2016 Oct 10;215(1):47-56. Epub 2016 Oct 3.

20.

Generation of human muscle fibers and satellite-like cells from human pluripotent stem cells in vitro.

Chal J, Al Tanoury Z, Hestin M, Gobert B, Aivio S, Hick A, Cherrier T, Nesmith AP, Parker KK, Pourquié O.

Nat Protoc. 2016 Oct;11(10):1833-50. doi: 10.1038/nprot.2016.110. Epub 2016 Sep 1.

21.

Phototactic guidance of a tissue-engineered soft-robotic ray.

Park SJ, Gazzola M, Park KS, Park S, Di Santo V, Blevins EL, Lind JU, Campbell PH, Dauth S, Capulli AK, Pasqualini FS, Ahn S, Cho A, Yuan H, Maoz BM, Vijaykumar R, Choi JW, Deisseroth K, Lauder GV, Mahadevan L, Parker KK.

Science. 2016 Jul 8;353(6295):158-62. doi: 10.1126/science.aaf4292.

22.

Microenvironmental Control of Adipocyte Fate and Function.

Pope BD, Warren CR, Parker KK, Cowan CA.

Trends Cell Biol. 2016 Oct;26(10):745-755. doi: 10.1016/j.tcb.2016.05.005. Epub 2016 Jun 4. Review.

PMID:
27268909
23.

Acute pergolide exposure stiffens engineered valve interstitial cell tissues and reduces contractility in vitro.

Capulli AK, MacQueen LA, O'Connor BB, Dauth S, Parker KK.

Cardiovasc Pathol. 2016 Jul-Aug;25(4):316-324. doi: 10.1016/j.carpath.2016.04.004. Epub 2016 Apr 25.

24.

Coupling primary and stem cell-derived cardiomyocytes in an in vitro model of cardiac cell therapy.

Aratyn-Schaus Y, Pasqualini FS, Yuan H, McCain ML, Ye GJ, Sheehy SP, Campbell PH, Parker KK.

J Cell Biol. 2016 Feb 15;212(4):389-97. doi: 10.1083/jcb.201508026. Epub 2016 Feb 8.

25.

Angiotensin II Induced Cardiac Dysfunction on a Chip.

Horton RE, Yadid M, McCain ML, Sheehy SP, Pasqualini FS, Park SJ, Cho A, Campbell P, Parker KK.

PLoS One. 2016 Jan 25;11(1):e0146415. doi: 10.1371/journal.pone.0146415. eCollection 2016.

26.

Extracellular matrix protein expression is brain region dependent.

Dauth S, Grevesse T, Pantazopoulos H, Campbell PH, Maoz BM, Berretta S, Parker KK.

J Comp Neurol. 2016 May 1;524(7):1309-36. doi: 10.1002/cne.23965. Epub 2016 Feb 1.

PMID:
26780384
27.

Fibrous scaffolds for building hearts and heart parts.

Capulli AK, MacQueen LA, Sheehy SP, Parker KK.

Adv Drug Deliv Rev. 2016 Jan 15;96:83-102. doi: 10.1016/j.addr.2015.11.020. Epub 2015 Dec 4. Review.

28.

Diagnostic tools for evaluating the impact of Focal Axonal Swellings arising in neurodegenerative diseases and/or traumatic brain injury.

Maia PD, Hemphill MA, Zehnder B, Zhang C, Parker KK, Kutz JN.

J Neurosci Methods. 2015 Sep 30;253:233-43. doi: 10.1016/j.jneumeth.2015.06.022. Epub 2015 Jul 16.

PMID:
26188255
29.

Cytoskeletal prestress regulates nuclear shape and stiffness in cardiac myocytes.

Lee H, Adams WJ, Alford PW, McCain ML, Feinberg AW, Sheehy SP, Goss JA, Parker KK.

Exp Biol Med (Maywood). 2015 Nov;240(11):1543-54. doi: 10.1177/1535370215583799. Epub 2015 Apr 23.

30.

Metrics for assessing cytoskeletal orientational correlations and consistency.

Drew NK, Eagleson MA, Baldo DB Jr, Parker KK, Grosberg A.

PLoS Comput Biol. 2015 Apr 7;11(4):e1004190. doi: 10.1371/journal.pcbi.1004190. eCollection 2015 Apr.

31.

Self-organizing large-scale extracellular-matrix protein networks.

Ahn S, Deravi LF, Park SJ, Dabiri BE, Kim JS, Parker KK, Shin K.

Adv Mater. 2015 May 13;27(18):2838-45. doi: 10.1002/adma.201405556. Epub 2015 Mar 31. No abstract available.

PMID:
25833069
32.

Opposite rheological properties of neuronal microcompartments predict axonal vulnerability in brain injury.

Grevesse T, Dabiri BE, Parker KK, Gabriele S.

Sci Rep. 2015 Mar 30;5:9475. doi: 10.1038/srep09475.

33.

Traumatic brain injury and the neuronal microenvironment: a potential role for neuropathological mechanotransduction.

Hemphill MA, Dauth S, Yu CJ, Dabiri BE, Parker KK.

Neuron. 2015 Mar 18;85(6):1177-92. doi: 10.1016/j.neuron.2015.02.041. Review.

34.

Structural phenotyping of stem cell-derived cardiomyocytes.

Pasqualini FS, Sheehy SP, Agarwal A, Aratyn-Schaus Y, Parker KK.

Stem Cell Reports. 2015 Mar 10;4(3):340-7. doi: 10.1016/j.stemcr.2015.01.020. Epub 2015 Feb 26.

35.

Engineered in vitro disease models.

Benam KH, Dauth S, Hassell B, Herland A, Jain A, Jang KJ, Karalis K, Kim HJ, MacQueen L, Mahmoodian R, Musah S, Torisawa YS, van der Meer AD, Villenave R, Yadid M, Parker KK, Ingber DE.

Annu Rev Pathol. 2015;10:195-262. doi: 10.1146/annurev-pathol-012414-040418. Review.

PMID:
25621660
36.

Effect of solvent evaporation on fiber morphology in rotary jet spinning.

Golecki HM, Yuan H, Glavin C, Potter B, Badrossamay MR, Goss JA, Phillips MD, Parker KK.

Langmuir. 2014 Nov 11;30(44):13369-74. doi: 10.1021/la5023104. Epub 2014 Oct 29.

37.

The role of mechanotransduction on vascular smooth muscle myocytes' [corrected] cytoskeleton and contractile function.

Ye GJ, Nesmith AP, Parker KK.

Anat Rec (Hoboken). 2014 Sep;297(9):1758-69. doi: 10.1002/ar.22983. Review. Erratum in: Anat Rec (Hoboken). 2015 Mar;298(3):637.

38.

Human airway musculature on a chip: an in vitro model of allergic asthmatic bronchoconstriction and bronchodilation.

Nesmith AP, Agarwal A, McCain ML, Parker KK.

Lab Chip. 2014 Oct 21;14(20):3925-36. doi: 10.1039/c4lc00688g.

39.

Approaching the in vitro clinical trial: engineering organs on chips.

Capulli AK, Tian K, Mehandru N, Bukhta A, Choudhury SF, Suchyta M, Parker KK.

Lab Chip. 2014 Sep 7;14(17):3181-6. doi: 10.1039/c4lc00276h.

40.

Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies.

Wang G, McCain ML, Yang L, He A, Pasqualini FS, Agarwal A, Yuan H, Jiang D, Zhang D, Zangi L, Geva J, Roberts AE, Ma Q, Ding J, Chen J, Wang DZ, Li K, Wang J, Wanders RJ, Kulik W, Vaz FM, Laflamme MA, Murry CE, Chien KR, Kelley RI, Church GM, Parker KK, Pu WT.

Nat Med. 2014 Jun;20(6):616-23. doi: 10.1038/nm.3545. Epub 2014 May 11.

41.

Micromolded gelatin hydrogels for extended culture of engineered cardiac tissues.

McCain ML, Agarwal A, Nesmith HW, Nesmith AP, Parker KK.

Biomaterials. 2014 Jul;35(21):5462-71. doi: 10.1016/j.biomaterials.2014.03.052. Epub 2014 Apr 14.

42.

Matrix elasticity regulates the optimal cardiac myocyte shape for contractility.

McCain ML, Yuan H, Pasqualini FS, Campbell PH, Parker KK.

Am J Physiol Heart Circ Physiol. 2014 Jun 1;306(11):H1525-39. doi: 10.1152/ajpheart.00799.2013. Epub 2014 Mar 28.

43.

Quality metrics for stem cell-derived cardiac myocytes.

Sheehy SP, Pasqualini F, Grosberg A, Park SJ, Aratyn-Schaus Y, Parker KK.

Stem Cell Reports. 2014 Mar 6;2(3):282-94. doi: 10.1016/j.stemcr.2014.01.015. eCollection 2014 Mar 11.

44.

Three-dimensional paper-based model for cardiac ischemia.

Mosadegh B, Dabiri BE, Lockett MR, Derda R, Campbell P, Parker KK, Whitesides GM.

Adv Healthc Mater. 2014 Jul;3(7):1036-43. doi: 10.1002/adhm.201300575. Epub 2014 Feb 12.

45.

The structure-function relationships of a natural nanoscale photonic device in cuttlefish chromatophores.

Deravi LF, Magyar AP, Sheehy SP, Bell GR, Mäthger LM, Senft SL, Wardill TJ, Lane WS, Kuzirian AM, Hanlon RT, Hu EL, Parker KK.

J R Soc Interface. 2014 Jan 29;11(93):20130942. doi: 10.1098/rsif.2013.0942. Print 2014 Apr 6.

46.

Engineering hybrid polymer-protein super-aligned nanofibers via rotary jet spinning.

Badrossamay MR, Balachandran K, Capulli AK, Golecki HM, Agarwal A, Goss JA, Kim H, Shin K, Parker KK.

Biomaterials. 2014 Mar;35(10):3188-97. doi: 10.1016/j.biomaterials.2013.12.072. Epub 2014 Jan 20.

47.

The contractile strength of vascular smooth muscle myocytes is shape dependent.

Ye GJ, Aratyn-Schaus Y, Nesmith AP, Pasqualini FS, Alford PW, Parker KK.

Integr Biol (Camb). 2014 Feb;6(2):152-63. doi: 10.1039/c3ib40230d.

PMID:
24406783
48.

Functional differences in engineered myocardium from embryonic stem cell-derived versus neonatal cardiomyocytes.

Feinberg AW, Ripplinger CM, van der Meer P, Sheehy SP, Domian I, Chien KR, Parker KK.

Stem Cell Reports. 2013 Nov 7;1(5):387-96. doi: 10.1016/j.stemcr.2013.10.004. eCollection 2013.

49.

Micropatterning Alginate Substrates for in vitro Cardiovascular Muscle on a Chip.

Agarwal A, Farouz Y, Nesmith AP, Deravi LF, McCain ML, Parker KK.

Adv Funct Mater. 2013 Aug 12;23(30):3738-3746.

50.

Microfluidic heart on a chip for higher throughput pharmacological studies.

Agarwal A, Goss JA, Cho A, McCain ML, Parker KK.

Lab Chip. 2013 Sep 21;13(18):3599-608. doi: 10.1039/c3lc50350j.

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