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A Mouse Model of Intestinal Partial Obstruction.

Ha SE, Wei L, Jorgensen BG, Lee MY, Park PJ, Poudrier SM, Ro S.

J Vis Exp. 2018 Mar 5;(133). doi: 10.3791/57381.


Epidemiology and Clinical Management of Traumatic Spine Injuries at a Major Government Hospital in Cambodia.

Choi JH, Park PJ, Din V, Sam N, Iv V, Park KB.

Asian Spine J. 2017 Dec;11(6):908-916. doi: 10.4184/asj.2017.11.6.908. Epub 2017 Dec 7.


Aging and neurodegeneration are associated with increased mutations in single human neurons.

Lodato MA, Rodin RE, Bohrson CL, Coulter ME, Barton AR, Kwon M, Sherman MA, Vitzthum CM, Luquette LJ, Yandava CN, Yang P, Chittenden TW, Hatem NE, Ryu SC, Woodworth MB, Park PJ, Walsh CA.

Science. 2018 Feb 2;359(6375):555-559. doi: 10.1126/science.aao4426. Epub 2017 Dec 7.


PaSD-qc: quality control for single cell whole-genome sequencing data using power spectral density estimation.

Sherman MA, Barton AR, Lodato MA, Vitzthum C, Coulter ME, Walsh CA, Park PJ.

Nucleic Acids Res. 2018 Feb 28;46(4):e20. doi: 10.1093/nar/gkx1195.


Corrigendum: The 4D nucleome project.

Dekker J, Belmont AS, Guttman M, Leshyk VO, Lis JT, Lomvardas S, Mirny LA, O'Shea CC, Park PJ, Ren B, Politz JCR, Shendure J, Zhong S; 4D Nucleome Network.

Nature. 2017 Dec 14;552(7684):278. doi: 10.1038/nature24667. Epub 2017 Nov 22.


Prevalence and detection of low-allele-fraction variants in clinical cancer samples.

Shin HT, Choi YL, Yun JW, Kim NKD, Kim SY, Jeon HJ, Nam JY, Lee C, Ryu D, Kim SC, Park K, Lee E, Bae JS, Son DS, Joung JG, Lee J, Kim ST, Ahn MJ, Lee SH, Ahn JS, Lee WY, Oh BY, Park YH, Lee JE, Lee KH, Kim HC, Kim KM, Im YH, Park K, Park PJ, Park WY.

Nat Commun. 2017 Nov 9;8(1):1377. doi: 10.1038/s41467-017-01470-y.


Bivalent complexes of PRC1 with orthologs of BRD4 and MOZ/MORF target developmental genes in Drosophila.

Kang H, Jung YL, McElroy KA, Zee BM, Wallace HA, Woolnough JL, Park PJ, Kuroda MI.

Genes Dev. 2017 Oct 1;31(19):1988-2002. doi: 10.1101/gad.305987.117. Epub 2017 Oct 25.


Understanding patient preferences for femoral central venous catheterization among patients with sickle cell disease.

Park PJ, Cole SS, Bercu ZL, Martin J, Newsome J.

J Vasc Access. 2018 Mar;19(2):199-200. doi: 10.5301/jva.5000794. Epub 2018 Feb 19. No abstract available.


The 4D nucleome project.

Dekker J, Belmont AS, Guttman M, Leshyk VO, Lis JT, Lomvardas S, Mirny LA, O'Shea CC, Park PJ, Ren B, Politz JCR, Shendure J, Zhong S; 4D Nucleome Network.

Nature. 2017 Sep 13;549(7671):219-226. doi: 10.1038/nature23884. Erratum in: Nature. 2017 Nov 22;:.


VEGF amplifies transcription through ETS1 acetylation to enable angiogenesis.

Chen J, Fu Y, Day DS, Sun Y, Wang S, Liang X, Gu F, Zhang F, Stevens SM, Zhou P, Li K, Zhang Y, Lin RZ, Smith LEH, Zhang J, Sun K, Melero-Martin JM, Han Z, Park PJ, Zhang B, Pu WT.

Nat Commun. 2017 Aug 29;8(1):383. doi: 10.1038/s41467-017-00405-x.


Taurine Attenuates Epithelial-Mesenchymal Transition-Related Genes in Human Prostate Cancer Cells.

Tang Y, Kim YS, Choi EJ, Hwang YJ, Yun YS, Bae SM, Park PJ, Kim EK.

Adv Exp Med Biol. 2017;975:1203-1212. doi: 10.1007/978-94-024-1079-2_96.


Protective Effect of Taurine on Mice with Doxorubicin-induced Acute Kidney Injury.

Kim YS, Sung SH, Tang Y, Choi EJ, Choi YJ, Hwang YJ, Park PJ, Kim EK.

Adv Exp Med Biol. 2017;975:1191-1201. doi: 10.1007/978-94-024-1079-2_95.


Taurine Attenuates Doxorubicin-Induced Toxicity on B16F10 Cells.

Kim YS, Kim EK, Hwang JW, Kim WS, Shin WB, Natarajan SB, Moon SH, Jeon BT, Park PJ.

Adv Exp Med Biol. 2017;975:1179-1190. doi: 10.1007/978-94-024-1079-2_94.


Antioxidant Effect of Taurine-Rich Paroctopus dofleini Extracts Through Inhibiting ROS Production Against LPS-Induced Oxidative Stress In Vitro and In Vivo Model.

Kim YS, Kim EK, Jeon NJ, Ryu BI, Hwang JW, Choi EJ, Moon SH, Jeon BT, Park PJ.

Adv Exp Med Biol. 2017;975:1165-1177. doi: 10.1007/978-94-024-1079-2_93.


Antioxidant Activity of Extract from the Cephalothorax of Fenneropenaeus chinensis.

Kim YS, Kim EK, Ryu BI, Jeon NJ, Hwang JW, Choi EJ, Moon SH, Jeon BT, Park PJ.

Adv Exp Med Biol. 2017;975:1153-1163. doi: 10.1007/978-94-024-1079-2_92.


Fermented Asterina pectinifera with Cordyceps militaris Mycelia Induced Apoptosis in B16F10 Melanoma Cells.

Kim YS, Kim EK, Hwang JW, Kim JS, Kim H, Dong X, Natarajan SB, Moon SH, Jeon BT, Park PJ.

Adv Exp Med Biol. 2017;975:1141-1152. doi: 10.1007/978-94-024-1079-2_91.


Neuroprotective Effect of Taurine-Rich Cuttlefish (Sepia officinalis) Extract Against Hydrogen Peroxide-Induced Oxidative Stress in SH-SY5Y Cells.

Kim YS, Kim EK, Hwang JW, Kim JS, Shin WB, Dong X, Nawarathna WPAS, Moon SH, Jeon BT, Park PJ.

Adv Exp Med Biol. 2017;975:243-254. doi: 10.1007/978-94-024-1079-2_22.


Transcriptome analysis of PDGFRα+ cells identifies T-type Ca2+ channel CACNA1G as a new pathological marker for PDGFRα+ cell hyperplasia.

Ha SE, Lee MY, Kurahashi M, Wei L, Jorgensen BG, Park C, Park PJ, Redelman D, Sasse KC, Becker LS, Sanders KM, Ro S.

PLoS One. 2017 Aug 14;12(8):e0182265. doi: 10.1371/journal.pone.0182265. eCollection 2017.


Clinical Application of Targeted Deep Sequencing in Solid-Cancer Patients and Utility for Biomarker-Selected Clinical Trials.

Kim ST, Kim KM, Kim NKD, Park JO, Ahn S, Yun JW, Kim KT, Park SH, Park PJ, Kim HC, Sohn TS, Choi DI, Cho JH, Heo JS, Kwon W, Lee H, Min BH, Hong SN, Park YS, Lim HY, Kang WK, Park WY, Lee J.

Oncologist. 2017 Oct;22(10):1169-1177. doi: 10.1634/theoncologist.2017-0020. Epub 2017 Jul 12.


The medicolegal landscape of spine surgery: how do surgeons fare?

Makhni MC, Park PJ, Jimenez J, Saifi C, Caldwell JM, Ha A, Figueroa-Santana B, Lehman RA Jr, Weidenbaum M.

Spine J. 2018 Feb;18(2):209-215. doi: 10.1016/j.spinee.2017.06.038. Epub 2017 Jun 30.


The Utility of Screening Colonoscopy During Kidney Transplant Evaluation.

Zheng Y, Chaung KV, Park PJ, Augustine JJ, Sarabu N, Schulak JA, Sanchez EQ, Humphreville VR, Ammori JB, Woodside KJ.

Exp Clin Transplant. 2017 Dec;15(6):602-608. doi: 10.6002/ect.2016.0214. Epub 2017 Jun 16.


A molecular portrait of microsatellite instability across multiple cancers.

Cortes-Ciriano I, Lee S, Park WY, Kim TM, Park PJ.

Nat Commun. 2017 Jun 6;8:15180. doi: 10.1038/ncomms15180.


A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations.

Zhang Y, Kwok-Shing Ng P, Kucherlapati M, Chen F, Liu Y, Tsang YH, de Velasco G, Jeong KJ, Akbani R, Hadjipanayis A, Pantazi A, Bristow CA, Lee E, Mahadeshwar HS, Tang J, Zhang J, Yang L, Seth S, Lee S, Ren X, Song X, Sun H, Seidman J, Luquette LJ, Xi R, Chin L, Protopopov A, Westbrook TF, Shelley CS, Choueiri TK, Ittmann M, Van Waes C, Weinstein JN, Liang H, Henske EP, Godwin AK, Park PJ, Kucherlapati R, Scott KL, Mills GB, Kwiatkowski DJ, Creighton CJ.

Cancer Cell. 2017 Jun 12;31(6):820-832.e3. doi: 10.1016/j.ccell.2017.04.013. Epub 2017 May 18.


Engineering and Functional Characterization of Fusion Genes Identifies Novel Oncogenic Drivers of Cancer.

Lu H, Villafane N, Dogruluk T, Grzeskowiak CL, Kong K, Tsang YH, Zagorodna O, Pantazi A, Yang L, Neill NJ, Kim YW, Creighton CJ, Verhaak RG, Mills GB, Park PJ, Kucherlapati R, Scott KL.

Cancer Res. 2017 Jul 1;77(13):3502-3512. doi: 10.1158/0008-5472.CAN-16-2745. Epub 2017 May 16.


Clonal History and Genetic Predictors of Transformation Into Small-Cell Carcinomas From Lung Adenocarcinomas.

Lee JK, Lee J, Kim S, Kim S, Youk J, Park S, An Y, Keam B, Kim DW, Heo DS, Kim YT, Kim JS, Kim SH, Lee JS, Lee SH, Park K, Ku JL, Jeon YK, Chung DH, Park PJ, Kim J, Kim TM, Ju YS.

J Clin Oncol. 2017 Sep 10;35(26):3065-3074. doi: 10.1200/JCO.2016.71.9096. Epub 2017 May 12.


PPARγ-mediated G-protein coupled receptor 120 signaling pathway promotes transcriptional activation of miR-143 in adipocytes.

Bae IS, Park PJ, Lee JH, Cho EG, Lee TR, Kim SH.

Gene. 2017 Aug 30;626:64-69. doi: 10.1016/j.gene.2017.05.016. Epub 2017 May 8.


Specific visible radiation facilitates lipolysis in mature 3T3-L1 adipocytes via rhodopsin-dependent β3-adrenergic signaling.

Park PJ, Cho JY, Cho EG.

Eur J Cell Biol. 2017 Jun;96(4):301-311. doi: 10.1016/j.ejcb.2017.03.015. Epub 2017 Apr 27.


Moringa oleifera from Cambodia Ameliorates Oxidative Stress, Hyperglycemia, and Kidney Dysfunction in Type 2 Diabetic Mice.

Tang Y, Choi EJ, Han WC, Oh M, Kim J, Hwang JY, Park PJ, Moon SH, Kim YS, Kim EK.

J Med Food. 2017 May;20(5):502-510. doi: 10.1089/jmf.2016.3792. Epub 2017 May 3.


Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network.

McConnell MJ, Moran JV, Abyzov A, Akbarian S, Bae T, Cortes-Ciriano I, Erwin JA, Fasching L, Flasch DA, Freed D, Ganz J, Jaffe AE, Kwan KY, Kwon M, Lodato MA, Mills RE, Paquola ACM, Rodin RE, Rosenbluh C, Sestan N, Sherman MA, Shin JH, Song S, Straub RE, Thorpe J, Weinberger DR, Urban AE, Zhou B, Gage FH, Lehner T, Senthil G, Walsh CA, Chess A, Courchesne E, Gleeson JG, Kidd JM, Park PJ, Pevsner J, Vaccarino FM; Brain Somatic Mosaicism Network.

Science. 2017 Apr 28;356(6336). pii: eaal1641. doi: 10.1126/science.aal1641. Epub 2017 Apr 27. Review.


Immune-Stimulatory Effects of Althaea rosea Flower Extracts through the MAPK Signaling Pathway in RAW264.7 Cells.

Kim YS, Kim EK, Nawarathna WPAS, Dong X, Shin WB, Park JS, Moon SH, Park PJ.

Molecules. 2017 Apr 25;22(5). pii: E679. doi: 10.3390/molecules22050679.


Transcriptome of interstitial cells of Cajal reveals unique and selective gene signatures.

Lee MY, Ha SE, Park C, Park PJ, Fuchs R, Wei L, Jorgensen BG, Redelman D, Ward SM, Sanders KM, Ro S.

PLoS One. 2017 Apr 20;12(4):e0176031. doi: 10.1371/journal.pone.0176031. eCollection 2017.


NGSCheckMate: software for validating sample identity in next-generation sequencing studies within and across data types.

Lee S, Lee S, Ouellette S, Park WY, Lee EA, Park PJ.

Nucleic Acids Res. 2017 Jun 20;45(11):e103. doi: 10.1093/nar/gkx193.


Spt5 Plays Vital Roles in the Control of Sense and Antisense Transcription Elongation.

Shetty A, Kallgren SP, Demel C, Maier KC, Spatt D, Alver BH, Cramer P, Park PJ, Winston F.

Mol Cell. 2017 Apr 6;66(1):77-88.e5. doi: 10.1016/j.molcel.2017.02.023. Epub 2017 Mar 30.


DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells.

Choi J, Clement K, Huebner AJ, Webster J, Rose CM, Brumbaugh J, Walsh RM, Lee S, Savol A, Etchegaray JP, Gu H, Boyle P, Elling U, Mostoslavsky R, Sadreyev R, Park PJ, Gygi SP, Meissner A, Hochedlinger K.

Cell Stem Cell. 2017 May 4;20(5):706-719.e7. doi: 10.1016/j.stem.2017.03.002. Epub 2017 Mar 30.


Biosynthesis of Oligomeric Anthocyanins from Grape Skin Extracts.

Hwang JW, Natarajan SB, Kim YS, Kim EK, Lee JW, Moon SH, Jeon BT, Park PJ.

Molecules. 2017 Mar 21;22(3). pii: E497. doi: 10.3390/molecules22030497.


The SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers.

Alver BH, Kim KH, Lu P, Wang X, Manchester HE, Wang W, Haswell JR, Park PJ, Roberts CW.

Nat Commun. 2017 Mar 6;8:14648. doi: 10.1038/ncomms14648.


Serum response factor regulates smooth muscle contractility via myotonic dystrophy protein kinases and L-type calcium channels.

Lee MY, Park C, Ha SE, Park PJ, Berent RM, Jorgensen BG, Corrigan RD, Grainger N, Blair PJ, Slivano OJ, Miano JM, Ward SM, Smith TK, Sanders KM, Ro S.

PLoS One. 2017 Feb 2;12(2):e0171262. doi: 10.1371/journal.pone.0171262. eCollection 2017.


Ocular promoting activity of grape polyphenols-A review.

Natarajan SB, Hwang JW, Kim YS, Kim EK, Park PJ.

Environ Toxicol Pharmacol. 2017 Mar;50:83-90. doi: 10.1016/j.etap.2016.12.004. Epub 2016 Dec 9. Review.


upSET, the Drosophila homologue of SET3, Is Required for Viability and the Proper Balance of Active and Repressive Chromatin Marks.

McElroy KA, Jung YL, Zee BM, Wang CI, Park PJ, Kuroda MI.

G3 (Bethesda). 2017 Feb 9;7(2):625-635. doi: 10.1534/g3.116.037788.


Pregnancy-Associated Risk Factors of Postpartum Breast Cancer in Korea: A Nationwide Health Insurance Database Study.

Kang EJ, Seo JH, Kim LY, Park GU, Oh MJ, Park PJ, Cho GJ.

PLoS One. 2016 Dec 15;11(12):e0168469. doi: 10.1371/journal.pone.0168469. eCollection 2016.


ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice.

Mathur R, Alver BH, San Roman AK, Wilson BG, Wang X, Agoston AT, Park PJ, Shivdasani RA, Roberts CW.

Nat Genet. 2017 Feb;49(2):296-302. doi: 10.1038/ng.3744. Epub 2016 Dec 12.


SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation.

Wang X, Lee RS, Alver BH, Haswell JR, Wang S, Mieczkowski J, Drier Y, Gillespie SM, Archer TC, Wu JN, Tzvetkov EP, Troisi EC, Pomeroy SL, Biegel JA, Tolstorukov MY, Bernstein BE, Park PJ, Roberts CW.

Nat Genet. 2017 Feb;49(2):289-295. doi: 10.1038/ng.3746. Epub 2016 Dec 12.


The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts.

Saini N, Roberts SA, Klimczak LJ, Chan K, Grimm SA, Dai S, Fargo DC, Boyer JC, Kaufmann WK, Taylor JA, Lee E, Cortes-Ciriano I, Park PJ, Schurman SH, Malc EP, Mieczkowski PA, Gordenin DA.

PLoS Genet. 2016 Oct 27;12(10):e1006385. doi: 10.1371/journal.pgen.1006385. eCollection 2016 Oct.


Genome Sequence Variability Predicts Drug Precautions and Withdrawals from the Market.

Lee KH, Baik SY, Lee SY, Park CH, Park PJ, Kim JH.

PLoS One. 2016 Sep 30;11(9):e0162135. doi: 10.1371/journal.pone.0162135. eCollection 2016.


Structural identification of the lipopolysaccharide-binding capability of a cupin-family protein from Helicobacter pylori.

Sim DW, Kim JH, Kim HY, Jang JH, Lee WC, Kim EH, Park PJ, Lee KH, Won HS.

FEBS Lett. 2016 Sep;590(17):2997-3004. doi: 10.1002/1873-3468.12332. Epub 2016 Aug 11.


Validation of the Intensive Care Unit Early Warning Dashboard: Quality Improvement Utilizing a Retrospective Case-Control Evaluation.

Kavanaugh MJ, So JD, Park PJ, Davis KL.

Telemed J E Health. 2017 Feb;23(2):88-95. doi: 10.1089/tmj.2016.0073. Epub 2016 Jul 8.


Anatomic Investigation of Commonly Used Landmarks for Evaluating Rotation During Forearm Fracture Reduction.

Weinberg DS, Park PJ, Boden KA, Malone KJ, Cooperman DR, Liu RW.

J Bone Joint Surg Am. 2016 Jul 6;98(13):1103-12. doi: 10.2106/JBJS.15.00845.


Copy number analysis of whole-genome data using BIC-seq2 and its application to detection of cancer susceptibility variants.

Xi R, Lee S, Xia Y, Kim TM, Park PJ.

Nucleic Acids Res. 2016 Jul 27;44(13):6274-86. doi: 10.1093/nar/gkw491. Epub 2016 Jun 3.


Comprehensive analysis of promoter-proximal RNA polymerase II pausing across mammalian cell types.

Day DS, Zhang B, Stevens SM, Ferrari F, Larschan EN, Park PJ, Pu WT.

Genome Biol. 2016 Jun 3;17(1):120. doi: 10.1186/s13059-016-0984-2.


Next-generation sequencing-based detection of germline L1-mediated transductions.

Tica J, Lee E, Untergasser A, Meiers S, Garfield DA, Gokcumen O, Furlong EE, Park PJ, Stütz AM, Korbel JO.

BMC Genomics. 2016 May 10;17:342. doi: 10.1186/s12864-016-2670-x.

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