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Items: 27


Antibody-mediated blockade of JMJD6 interaction with collagen I exerts antifibrotic and antimetastatic activities.

Miotti S, Gulino A, Ferri R, Parenza M, Chronowska A, Lecis D, Sangaletti S, Tagliabue E, Tripodo C, Colombo MP.

FASEB J. 2017 Dec;31(12):5356-5370. doi: 10.1096/fj.201700377R. Epub 2017 Aug 8.


Trabectedin Overrides Osteosarcoma Differentiative Block and Reprograms the Tumor Immune Environment Enabling Effective Combination with Immune Checkpoint Inhibitors.

Ratti C, Botti L, Cancila V, Galvan S, Torselli I, Garofalo C, Manara MC, Bongiovanni L, Valenti CF, Burocchi A, Parenza M, Cappetti B, Sangaletti S, Tripodo C, Scotlandi K, Colombo MP, Chiodoni C.

Clin Cancer Res. 2017 Sep 1;23(17):5149-5161. doi: 10.1158/1078-0432.CCR-16-3186. Epub 2017 Jun 9.


Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills Seminal Vesicle Epithelial-Stromal Tumors by Targeting PDGFR-β.

Jachetti E, Rigoni A, Bongiovanni L, Arioli I, Botti L, Parenza M, Cancila V, Chiodoni C, Festinese F, Bellone M, Tardanico R, Tripodo C, Colombo MP.

Mol Cancer Ther. 2017 Feb;16(2):365-375. doi: 10.1158/1535-7163.MCT-16-0466. Epub 2016 Dec 15.


Mesenchymal Transition of High-Grade Breast Carcinomas Depends on Extracellular Matrix Control of Myeloid Suppressor Cell Activity.

Sangaletti S, Tripodo C, Santangelo A, Castioni N, Portararo P, Gulino A, Botti L, Parenza M, Cappetti B, Orlandi R, Tagliabue E, Chiodoni C, Colombo MP.

Cell Rep. 2016 Sep 27;17(1):233-248. doi: 10.1016/j.celrep.2016.08.075.


Ultrasound-guided intra-tumor injection of combined immunotherapy cures mice from orthotopic prostate cancer.

Mauri G, Chiodoni C, Parenza M, Arioli I, Tripodo C, Colombo MP.

Cancer Immunol Immunother. 2013 Dec;62(12):1811-9. doi: 10.1007/s00262-013-1486-7. Epub 2013 Oct 18.


Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity.

Sangaletti S, Tripodo C, Chiodoni C, Guarnotta C, Cappetti B, Casalini P, Piconese S, Parenza M, Guiducci C, Vitali C, Colombo MP.

Blood. 2012 Oct 11;120(15):3007-18. doi: 10.1182/blood-2012-03-416156. Epub 2012 Aug 29.


SPARC oppositely regulates inflammation and fibrosis in bleomycin-induced lung damage.

Sangaletti S, Tripodo C, Cappetti B, Casalini P, Chiodoni C, Piconese S, Santangelo A, Parenza M, Arioli I, Miotti S, Colombo MP.

Am J Pathol. 2011 Dec;179(6):3000-10. doi: 10.1016/j.ajpath.2011.08.027. Epub 2011 Oct 11. Erratum in: Am J Pathol. 2012 Mar;180(3):1324.


Mast cell targeting hampers prostate adenocarcinoma development but promotes the occurrence of highly malignant neuroendocrine cancers.

Pittoni P, Tripodo C, Piconese S, Mauri G, Parenza M, Rigoni A, Sangaletti S, Colombo MP.

Cancer Res. 2011 Sep 15;71(18):5987-97. doi: 10.1158/0008-5472.CAN-11-1637. Epub 2011 Sep 6.


Macrophage-derived SPARC bridges tumor cell-extracellular matrix interactions toward metastasis.

Sangaletti S, Di Carlo E, Gariboldi S, Miotti S, Cappetti B, Parenza M, Rumio C, Brekken RA, Chiodoni C, Colombo MP.

Cancer Res. 2008 Nov 1;68(21):9050-9. doi: 10.1158/0008-5472.CAN-08-1327.


In Ewing's sarcoma CCN3(NOV) inhibits proliferation while promoting migration and invasion of the same cell type.

Benini S, Perbal B, Zambelli D, Colombo MP, Manara MC, Serra M, Parenza M, Martinez V, Picci P, Scotlandi K.

Oncogene. 2005 Jun 23;24(27):4349-61.


Reconstitution of human telomerase reverse transcriptase expression rescues colorectal carcinoma cells from in vitro senescence: evidence against immortality as a constitutive trait of tumor cells.

Dalerba P, Guiducci C, Poliani PL, Cifola I, Parenza M, Frattini M, Gallino G, Carnevali I, Di Giulio I, Andreola S, Lombardo C, Rivoltini L, Schweighoffer T, Belli F, Colombo MP, Parmiani G, Castelli C.

Cancer Res. 2005 Mar 15;65(6):2321-9.


Enhanced efficacy of tumor cell vaccines transfected with secretable hsp70.

Massa C, Guiducci C, Arioli I, Parenza M, Colombo MP, Melani C.

Cancer Res. 2004 Feb 15;64(4):1502-8.


Autologous and MHC class I-negative allogeneic tumor cells secreting IL-12 together cure disseminated A20 lymphoma.

Curti A, Parenza M, Colombo MP.

Blood. 2003 Jan 15;101(2):568-75. Epub 2002 Aug 22.


HOXB7: a key factor for tumor-associated angiogenic switch.

Carè A, Felicetti F, Meccia E, Bottero L, Parenza M, Stoppacciaro A, Peschle C, Colombo MP.

Cancer Res. 2001 Sep 1;61(17):6532-9.


IgG2a induced by interleukin (IL) 12-producing tumor cell vaccines but not IgG1 induced by IL-4 vaccine is associated with the eradication of experimental metastases.

Rodolfo M, Melani C, Zilocchi C, Cappetti B, Luison E, Arioli I, Parenza M, Canevari S, Colombo MP.

Cancer Res. 1998 Dec 15;58(24):5812-7.


Interleukin 12 gene therapy of MHC-negative murine melanoma metastases.

Nanni P, Rossi I, De Giovanni C, Landuzzi L, Nicoletti G, Stoppacciaro A, Parenza M, Colombo MP, Lollini PL.

Cancer Res. 1998 Mar 15;58(6):1225-30.


Amount of interleukin 12 available at the tumor site is critical for tumor regression.

Colombo MP, Vagliani M, Spreafico F, Parenza M, Chiodoni C, Melani C, Stoppacciaro A.

Cancer Res. 1996 Jun 1;56(11):2531-4.


Hypoxic tumor cell death and modulation of endothelial adhesion molecules in the regression of granulocyte colony-stimulating factor-transduced tumors.

Colombo MP, Lombardi L, Melani C, Parenza M, Baroni C, Ruco L, Stoppacciaro A.

Am J Pathol. 1996 Feb;148(2):473-83.


Interleukin 12 potentiates the curative effect of a vaccine based on interleukin 2-transduced tumor cells.

Vagliani M, Rodolfo M, Cavallo F, Parenza M, Melani C, Parmiani G, Forni G, Colombo MP.

Cancer Res. 1996 Feb 1;56(3):467-70.


Regression of an established tumor genetically modified to release granulocyte colony-stimulating factor requires granulocyte-T cell cooperation and T cell-produced interferon gamma.

Stoppacciaro A, Melani C, Parenza M, Mastracchio A, Bassi C, Baroni C, Parmiani G, Colombo MP.

J Exp Med. 1993 Jul 1;178(1):151-61.


Granulocyte colony-stimulating factor gene transfer suppresses tumorigenicity of a murine adenocarcinoma in vivo.

Colombo MP, Ferrari G, Stoppacciaro A, Parenza M, Rodolfo M, Mavilio F, Parmiani G.

J Exp Med. 1991 Apr 1;173(4):889-97.


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