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Items: 37


Food and feed safety of DAS-444Ø6-6 herbicide-tolerant soybean.

Herman RA, Ekmay RD, Schafer BW, Song P, Fast BJ, Papineni S, Shan G, Juberg DR.

Regul Toxicol Pharmacol. 2018 Jan 25;94:70-74. doi: 10.1016/j.yrtph.2018.01.016. [Epub ahead of print] Review.


Evaluation of 30% DAS-444Ø6-6 soybean meal in a subchronic rat toxicity study.

Papineni S, Passage JK, Ekmay RD, Thomas J.

Regul Toxicol Pharmacol. 2018 Jan 6;94:57-69. doi: 10.1016/j.yrtph.2018.01.005. [Epub ahead of print]


No treatment-related effects with aryloxyalkanoate dioxygenase-12 in three 28-day mouse toxicity studies.

Papineni S, Thomas J, Marshall VA, Juberg DR, Herman RA.

Regul Toxicol Pharmacol. 2018 Feb;92:220-225. doi: 10.1016/j.yrtph.2017.12.012. Epub 2017 Dec 16.


Safety evaluation of DAS-44406-6 soybeans in Wistar rats.

Qian Z, Bultman J, Papineni S, He N, Lanigan L, Herman RA, Hard GC.

Regul Toxicol Pharmacol. 2018 Feb;92:152-164. doi: 10.1016/j.yrtph.2017.11.016. Epub 2017 Dec 1.


Functional classification of protein toxins as a basis for bioinformatic screening.

Negi SS, Schein CH, Ladics GS, Mirsky H, Chang P, Rascle JB, Kough J, Sterck L, Papineni S, Jez JM, Pereira Mouriès L, Braun W.

Sci Rep. 2017 Oct 24;7(1):13940. doi: 10.1038/s41598-017-13957-1.


The aryloxyalkanoate dioxygenase-12 (AAD-12) protein is not acutely toxic in mice.

Papineni S, Golden RM, Thomas J.

Food Chem Toxicol. 2017 Dec;110:200-203. doi: 10.1016/j.fct.2017.10.036. Epub 2017 Oct 21.


Evaluation of the safety of a genetically modified DAS-444Ø6-6 soybean meal and hulls in a 90-day dietary toxicity study in rats.

Papineni S, Murray JA, Ricardo E, Dunville CM, Sura RK, Thomas J.

Food Chem Toxicol. 2017 Nov;109(Pt 1):245-252. doi: 10.1016/j.fct.2017.08.048. Epub 2017 Sep 1.


Comparative performance of broilers fed diets containing DAS-44406-6 and non-transgenic soybean meal.

Papineni S, Fletcher DW, Cromwell GL, Ekmay RD.

Poult Sci. 2017 May 1;96(5):1244-1249. doi: 10.3382/ps/pew384.


A predictive data-driven framework for endocrine prioritization: a triazole fungicide case study.

Paul Friedman K, Papineni S, Marty MS, Yi KD, Goetz AK, Rasoulpour RJ, Kwiatkowski P, Wolf DC, Blacker AM, Peffer RC.

Crit Rev Toxicol. 2016 Oct;46(9):785-833. doi: 10.1080/10408444.2016.1193722. Epub 2016 Jun 27. Review.


Assessment of potential adjuvanticity of Cry proteins.

Joshi SS, Barnett B, Doerrer NG, Glenn K, Herman RA, Herouet-Guicheney C, Hunst P, Kough J, Ladics GS, McClain S, Papineni S, Poulsen LK, Rascle JB, Tao AL, van Ree R, Ward J, Bowman CC.

Regul Toxicol Pharmacol. 2016 Aug;79:149-155. doi: 10.1016/j.yrtph.2016.04.005. Epub 2016 Apr 20. Review.


Pronamide: Weight of evidence for potential estrogen, androgen or thyroid effects.

Marty MS, Papineni S, Coady KK, Rasoulpour RJ, Pottenger LH, Eisenbrandt DL.

Regul Toxicol Pharmacol. 2015 Jul;72(2):405-22. doi: 10.1016/j.yrtph.2015.03.016. Epub 2015 Apr 4.


Pronamide: Human relevance of liver-mediated rat leydig cell tumors.

Rasoulpour RJ, Andrus AK, Marty MS, Zhang F, Thomas J, LeBaron MJ, Papineni S, Pottenger LH, Eisenbrandt DL.

Regul Toxicol Pharmacol. 2015 Jul;72(2):394-404. doi: 10.1016/j.yrtph.2015.03.012. Epub 2015 Apr 4.


Mode of action and human relevance of pronamide-induced rat thyroid tumors.

Papineni S, Marty MS, Rasoulpour RJ, LeBaron MJ, Pottenger LH, Eisenbrandt DL.

Regul Toxicol Pharmacol. 2015 Apr;71(3):541-51. doi: 10.1016/j.yrtph.2015.02.012. Epub 2015 Feb 20. Review.


Characterization of nuclear receptor-mediated murine hepatocarcinogenesis of the herbicide pronamide and its human relevance.

LeBaron MJ, Rasoulpour RJ, Gollapudi BB, Sura R, Kan HL, Schisler MR, Pottenger LH, Papineni S, Eisenbrandt DL.

Toxicol Sci. 2014 Nov;142(1):74-92. doi: 10.1093/toxsci/kfu155. Epub 2014 Aug 4.


Inhibition of pituitary tumor-transforming gene-1 in thyroid cancer cells by drugs that decrease specificity proteins.

Chintharlapalli S, Papineni S, Lee SO, Lei P, Jin UH, Sherman SI, Santarpia L, Safe S.

Mol Carcinog. 2011 Sep;50(9):655-67. doi: 10.1002/mc.20738. Epub 2011 Jan 25.


Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth.

Lee SO, Abdelrahim M, Yoon K, Chintharlapalli S, Papineni S, Kim K, Wang H, Safe S.

Cancer Res. 2010 Sep 1;70(17):6824-36. doi: 10.1158/0008-5472.CAN-10-1992. Epub 2010 Jul 21.


Peroxisome proliferator-activated receptor gamma-dependent activity of indole ring-substituted 1,1-bis(3'-indolyl)-1-(p-biphenyl)methanes in cancer cells.

Guo J, Chintharlapalli S, Lee SO, Cho SD, Lei P, Papineni S, Safe S.

Cancer Chemother Pharmacol. 2010 May;66(1):141-50. doi: 10.1007/s00280-009-1144-0. Epub 2009 Oct 13.


p21 expression is induced by activation of nuclear nerve growth factor-induced Balpha (Nur77) in pancreatic cancer cells.

Lee SO, Chintharlapalli S, Liu S, Papineni S, Cho SD, Yoon K, Safe S.

Mol Cancer Res. 2009 Jul;7(7):1169-78. doi: 10.1158/1541-7786.MCR-08-0473. Epub 2009 Jul 7.


Oncogenic microRNA-27a is a target for anticancer agent methyl 2-cyano-3,11-dioxo-18beta-olean-1,12-dien-30-oate in colon cancer cells.

Chintharlapalli S, Papineni S, Abdelrahim M, Abudayyeh A, Jutooru I, Chadalapaka G, Wu F, Mertens-Talcott S, Vanderlaag K, Cho SD, Smith R 3rd, Safe S.

Int J Cancer. 2009 Oct 15;125(8):1965-74. doi: 10.1002/ijc.24530.


Tolfenamic acid inhibits esophageal cancer through repression of specificity proteins and c-Met.

Papineni S, Chintharlapalli S, Abdelrahim M, Lee SO, Burghardt R, Abudayyeh A, Baker C, Herrera L, Safe S.

Carcinogenesis. 2009 Jul;30(7):1193-201. doi: 10.1093/carcin/bgp092. Epub 2009 Apr 30.


Induction of apoptosis and nonsteroidal anti-inflammatory drug-activated gene 1 in pancreatic cancer cells by a glycyrrhetinic acid derivative.

Jutooru I, Chadalapaka G, Chintharlapalli S, Papineni S, Safe S.

Mol Carcinog. 2009 Aug;48(8):692-702. doi: 10.1002/mc.20518.


1,1-Bis(3'-indolyl)-1-(p-chlorophenyl)methane activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth.

Inamoto T, Papineni S, Chintharlapalli S, Cho SD, Safe S, Kamat AM.

Mol Cancer Ther. 2008 Dec;7(12):3825-33. doi: 10.1158/1535-7163.MCT-08-0730.


5,5'-Dibromo-bis(3'-indolyl)methane induces Kruppel-like factor 4 and p21 in colon cancer cells.

Cho SD, Chintharlapalli S, Abdelrahim M, Papineni S, Liu S, Guo J, Lei P, Abudayyeh A, Safe S.

Mol Cancer Ther. 2008 Jul;7(7):2109-20. doi: 10.1158/1535-7163.MCT-07-2311.


Curcumin decreases specificity protein expression in bladder cancer cells.

Chadalapaka G, Jutooru I, Chintharlapalli S, Papineni S, Smith R 3rd, Li X, Safe S.

Cancer Res. 2008 Jul 1;68(13):5345-54. doi: 10.1158/0008-5472.CAN-07-6805.


Cancer chemotherapy with indole-3-carbinol, bis(3'-indolyl)methane and synthetic analogs.

Safe S, Papineni S, Chintharlapalli S.

Cancer Lett. 2008 Oct 8;269(2):326-38. doi: 10.1016/j.canlet.2008.04.021. Epub 2008 May 22. Review.


1,1-bis(3'-indolyl)-1-(p-methoxyphenyl)methane activates Nur77-independent proapoptotic responses in colon cancer cells.

Cho SD, Lei P, Abdelrahim M, Yoon K, Liu S, Guo J, Papineni S, Chintharlapalli S, Safe S.

Mol Carcinog. 2008 Apr;47(4):252-63.


2-cyano-lup-1-en-3-oxo-20-oic acid, a cyano derivative of betulinic acid, activates peroxisome proliferator-activated receptor gamma in colon and pancreatic cancer cells.

Chintharlapalli S, Papineni S, Liu S, Jutooru I, Chadalapaka G, Cho SD, Murthy RS, You Y, Safe S.

Carcinogenesis. 2007 Nov;28(11):2337-46. Epub 2007 Aug 27.


Betulinic acid inhibits prostate cancer growth through inhibition of specificity protein transcription factors.

Chintharlapalli S, Papineni S, Ramaiah SK, Safe S.

Cancer Res. 2007 Mar 15;67(6):2816-23.


The role of xenoestrogenic compounds in the development of breast cancer.

Safe S, Papineni S.

Trends Pharmacol Sci. 2006 Aug;27(8):447-54. Epub 2006 Jul 5. Review.


Activation of Nur77 by selected 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induces apoptosis through nuclear pathways.

Chintharlapalli S, Burghardt R, Papineni S, Ramaiah S, Yoon K, Safe S.

J Biol Chem. 2005 Jul 1;280(26):24903-14. Epub 2005 May 3.


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