Sort by
Items per page

Send to

Choose Destination

Search results

Items: 35


Inhibition of DDR1-BCR signalling by nilotinib as a new therapeutic strategy for metastatic colorectal cancer.

Jeitany M, Leroy C, Tosti P, Lafitte M, Le Guet J, Simon V, Bonenfant D, Robert B, Grillet F, Mollevi C, El Messaoudi S, Otandault A, Canterel-Thouennon L, Busson M, Thierry AR, Martineau P, Pannequin J, Roche S, Sirvent A.

EMBO Mol Med. 2018 Feb 9. pii: e7918. doi: 10.15252/emmm.201707918. [Epub ahead of print]


[Cancer stem cells and metastatic dissemination].

Pannequin J.

Bull Cancer. 2017 Dec;104(12):1091-1093. doi: 10.1016/j.bulcan.2017.10.014. Epub 2017 Nov 15. French. No abstract available.


[Cancer stem cells in colon cancer].

Pannequin J.

Bull Cancer. 2017 Dec;104(12):1072-1074. doi: 10.1016/j.bulcan.2017.10.016. Epub 2017 Nov 16. French. No abstract available.


Translational reprogramming of colorectal cancer cells induced by 5-fluorouracil through a miRNA-dependent mechanism.

Bash-Imam Z, Thérizols G, Vincent A, Lafôrets F, Polay Espinoza M, Pion N, Macari F, Pannequin J, David A, Saurin JC, Mertani HC, Textoris J, Auboeuf D, Catez F, Dalla Venezia N, Dutertre M, Marcel V, Diaz JJ.

Oncotarget. 2017 Jul 11;8(28):46219-46233. doi: 10.18632/oncotarget.17597.


Bases fondamentales du processus métastatique.

Pascussi JM, Giraud J, Samalin E, Grillet F, Pannequin J.

Bull Cancer. 2016 Jun;103(6 Suppl 1):S39-47. doi: 10.1016/S0007-4551(16)30144-8. Review. French.


Circulating tumour cells from patients with colorectal cancer have cancer stem cell hallmarks in ex vivo culture.

Grillet F, Bayet E, Villeronce O, Zappia L, Lagerqvist EL, Lunke S, Charafe-Jauffret E, Pham K, Molck C, Rolland N, Bourgaux JF, Prudhomme M, Philippe C, Bravo S, Boyer JC, Canterel-Thouennon L, Taylor GR, Hsu A, Pascussi JM, Hollande F, Pannequin J.

Gut. 2017 Oct;66(10):1802-1810. doi: 10.1136/gutjnl-2016-311447. Epub 2016 Jul 25.


Pregnane X-receptor promotes stem cell-mediated colon cancer relapse.

Planque C, Rajabi F, Grillet F, Finetti P, Bertucci F, Gironella M, Lozano JJ, Beucher B, Giraud J, Garambois V, Vincent C, Brown D, Caillo L, Kantar J, Pelegrin A, Prudhomme M, Ripoche J, Bourgaux JF, Ginestier C, Castells A, Hollande F, Pannequin J, Pascussi JM.

Oncotarget. 2016 Aug 30;7(35):56558-56573. doi: 10.18632/oncotarget.10646.


Autocrine Secretion of Progastrin Promotes the Survival and Self-Renewal of Colon Cancer Stem-like Cells.

Giraud J, Failla LM, Pascussi JM, Lagerqvist EL, Ollier J, Finetti P, Bertucci F, Ya C, Gasmi I, Bourgaux JF, Prudhomme M, Mazard T, Ait-Arsa I, Houhou L, Birnbaum D, Pélegrin A, Vincent C, Ryall JG, Joubert D, Pannequin J, Hollande F.

Cancer Res. 2016 Jun 15;76(12):3618-28. doi: 10.1158/0008-5472.CAN-15-1497. Epub 2016 May 4.


Antibiotics inhibit sphere-forming ability in suspension culture.

Relier S, Yazdani L, Ayad O, Choquet A, Bourgaux JF, Prudhomme M, Pannequin J, Macari F, David A.

Cancer Cell Int. 2016 Feb 12;16:6. doi: 10.1186/s12935-016-0277-6. eCollection 2016.


TRM6/61 connects PKCα with translational control through tRNAi(Met) stabilization: impact on tumorigenesis.

Macari F, El-Houfi Y, Boldina G, Xu H, Khoury-Hanna S, Ollier J, Yazdani L, Zheng G, Bièche I, Legrand N, Paulet D, Durrieu S, Byström A, Delbecq S, Lapeyre B, Bauchet L, Pannequin J, Hollande F, Pan T, Teichmann M, Vagner S, David A, Choquet A, Joubert D.

Oncogene. 2016 Apr 7;35(14):1785-96. doi: 10.1038/onc.2015.244. Epub 2015 Aug 3.


The p53 isoform Δ133p53β promotes cancer stem cell potential.

Arsic N, Gadea G, Lagerqvist EL, Busson M, Cahuzac N, Brock C, Hollande F, Gire V, Pannequin J, Roux P.

Stem Cell Reports. 2015 Apr 14;4(4):531-40. doi: 10.1016/j.stemcr.2015.02.001. Epub 2015 Mar 5.


Characterization of a novel PXR isoform with potential dominant-negative properties.

Breuker C, Planque C, Rajabi F, Nault JC, Couchy G, Zucman-Rossi J, Evrard A, Kantar J, Chevet E, Bioulac-Sage P, Ramos J, Assenat E, Joubert D, Pannequin J, Hollande F, Pascussi JM.

J Hepatol. 2014 Sep;61(3):609-16. doi: 10.1016/j.jhep.2014.04.030. Epub 2014 May 2.


RIP140 increases APC expression and controls intestinal homeostasis and tumorigenesis.

Lapierre M, Bonnet S, Bascoul-Mollevi C, Ait-Arsa I, Jalaguier S, Del Rio M, Plateroti M, Roepman P, Ychou M, Pannequin J, Hollande F, Parker M, Cavailles V.

J Clin Invest. 2014 May;124(5):1899-913. doi: 10.1172/JCI65178. Epub 2014 Mar 25.


SLAP displays tumour suppressor functions in colorectal cancer via destabilization of the SRC substrate EPHA2.

Naudin C, Sirvent A, Leroy C, Larive R, Simon V, Pannequin J, Bourgaux JF, Pierre J, Robert B, Hollande F, Roche S.

Nat Commun. 2014;5:3159. doi: 10.1038/ncomms4159.


Essential requirement for β-arrestin2 in mouse intestinal tumors with elevated Wnt signaling.

Bonnans C, Flacelière M, Grillet F, Dantec C, Desvignes JP, Pannequin J, Severac D, Dubois E, Bibeau F, Escriou V, Crespy P, Journot L, Hollande F, Joubert D.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):3047-52. doi: 10.1073/pnas.1109457109. Epub 2012 Feb 6.


The long road to colorectal cancer therapy: searching for the right signals.

Hollande F, Pannequin J, Joubert D.

Drug Resist Updat. 2010 Feb-Apr;13(1-2):44-56. doi: 10.1016/j.drup.2009.01.002. Epub 2010 Feb 21. Review.


Symplekin promotes tumorigenicity by up-regulating claudin-2 expression.

Buchert M, Papin M, Bonnans C, Darido C, Raye WS, Garambois V, Pélegrin A, Bourgaux JF, Pannequin J, Joubert D, Hollande F.

Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2628-33. doi: 10.1073/pnas.0903747107. Epub 2010 Jan 25.


Src family tyrosine kinases-driven colon cancer cell invasion is induced by Csk membrane delocalization.

Sirvent A, Bénistant C, Pannequin J, Veracini L, Simon V, Bourgaux JF, Hollande F, Cruzalegui F, Roche S.

Oncogene. 2010 Mar 4;29(9):1303-15. doi: 10.1038/onc.2009.450. Epub 2009 Dec 14.


The wnt target jagged-1 mediates the activation of notch signaling by progastrin in human colorectal cancer cells.

Pannequin J, Bonnans C, Delaunay N, Ryan J, Bourgaux JF, Joubert D, Hollande F.

Cancer Res. 2009 Aug 1;69(15):6065-73. doi: 10.1158/0008-5472.CAN-08-2409. Epub 2009 Jul 21.


The symplekin/ZONAB complex inhibits intestinal cell differentiation by the repression of AML1/Runx1.

Buchert M, Darido C, Lagerqvist E, Sedello A, Cazevieille C, Buchholz F, Bourgaux JF, Pannequin J, Joubert D, Hollande F.

Gastroenterology. 2009 Jul;137(1):156-64, 164.e1-3. doi: 10.1053/j.gastro.2009.03.037. Epub 2009 Mar 27.


Defective claudin-7 regulation by Tcf-4 and Sox-9 disrupts the polarity and increases the tumorigenicity of colorectal cancer cells.

Darido C, Buchert M, Pannequin J, Bastide P, Zalzali H, Mantamadiotis T, Bourgaux JF, Garambois V, Jay P, Blache P, Joubert D, Hollande F.

Cancer Res. 2008 Jun 1;68(11):4258-68. doi: 10.1158/0008-5472.CAN-07-5805.


Phosphatidylethanol accumulation promotes intestinal hyperplasia by inducing ZONAB-mediated cell density increase in response to chronic ethanol exposure.

Pannequin J, Delaunay N, Darido C, Maurice T, Crespy P, Frohman MA, Balda MS, Matter K, Joubert D, Bourgaux JF, Bali JP, Hollande F.

Mol Cancer Res. 2007 Nov;5(11):1147-57.


Beta-catenin/Tcf-4 inhibition after progastrin targeting reduces growth and drives differentiation of intestinal tumors.

Pannequin J, Delaunay N, Buchert M, Surrel F, Bourgaux JF, Ryan J, Boireau S, Coelho J, Pélegrin A, Singh P, Shulkes A, Yim M, Baldwin GS, Pignodel C, Lambeau G, Jay P, Joubert D, Hollande F.

Gastroenterology. 2007 Nov;133(5):1554-68. Epub 2007 Oct 24.


Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium.

Bastide P, Darido C, Pannequin J, Kist R, Robine S, Marty-Double C, Bibeau F, Scherer G, Joubert D, Hollande F, Blache P, Jay P.

J Cell Biol. 2007 Aug 13;178(4):635-48.


DNA-methylation-dependent alterations of claudin-4 expression in human bladder carcinoma.

Boireau S, Buchert M, Samuel MS, Pannequin J, Ryan JL, Choquet A, Chapuis H, Rebillard X, Avancès C, Ernst M, Joubert D, Mottet N, Hollande F.

Carcinogenesis. 2007 Feb;28(2):246-58. Epub 2006 Jul 8.


Glycine-extended gastrin activates two independent tyrosine-kinases in upstream of p85/p110 phosphatidylinositol 3-kinase in human colonic tumour cells.

Ferrand A, Kowalski-Chauvel A, Pannequin J, Bertrand C, Fourmy D, Dufresne M, Seva C.

World J Gastroenterol. 2006 Mar 28;12(12):1859-64.


Glycine-extended gastrin stimulates cell proliferation and migration through a Rho- and ROCK-dependent pathway, not a Rac/Cdc42-dependent pathway.

He H, Pannequin J, Tantiongco JP, Shulkes A, Baldwin GS.

Am J Physiol Gastrointest Liver Physiol. 2005 Sep;289(3):G478-88. Epub 2005 Apr 21.


Divergent roles for ferric ions in the biological activity of amidated and non-amidated gastrins.

Pannequin J, Tantiongco JP, Kovac S, Shulkes A, Baldwin GS.

J Endocrinol. 2004 May;181(2):315-25.


A novel effect of bismuth ions: selective inhibition of the biological activity of glycine-extended gastrin.

Pannequin J, Kovac S, Tantiongco JP, Norton RS, Shulkes A, Barnham KJ, Baldwin GS.

J Biol Chem. 2004 Jan 23;279(4):2453-60. Epub 2003 Oct 6.


Preparation of biologically active recombinant human progastrin(1-80).

McQueen K, Kovac S, Ho PK, Rorison K, Pannequin J, Neumann G, Shulkes A, Baldwin GS.

J Protein Chem. 2002 Oct;21(7):465-71.


Ferric ions are essential for the biological activity of the hormone glycine-extended gastrin.

Pannequin J, Barnham KJ, Hollande F, Shulkes A, Norton RS, Baldwin GS.

J Biol Chem. 2002 Dec 13;277(50):48602-9. Epub 2002 Sep 20.


C-terminal heptapeptide of gastrin inhibits astrocytomas motility by interacting with a new gastrin binding site.

Pannequin J, Oiry C, Morel C, Kucharczak J, Camby I, Kiss R, Gagne D, Galleyrand JC, Martinez J.

J Pharmacol Exp Ther. 2002 Jul;302(1):274-82.


Gastrin induces over-expression of genes involved in human U373 glioblastoma cell migration.

Kucharczak J, Pannequin J, Camby I, Decaestecker C, Kiss R, Martinez J.

Oncogene. 2001 Oct 25;20(48):7021-8.


A synthetic glycine-extended bombesin analogue interacts with the GRP/bombesin receptor.

Oiry C, Pannequin J, Bernad N, Artis AM, Galleyrand JC, Devin C, Cristau M, Fehrentz JA, Martinez J.

Eur J Pharmacol. 2000 Sep 1;403(1-2):17-25.


L-365,260 inhibits in vitro acid secretion by interacting with a PKA pathway.

Oiry C, Pannequin J, Cormier A, Galleyrand JC, Martinez J.

Br J Pharmacol. 1999 May;127(1):259-67.

Supplemental Content

Loading ...
Support Center