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Items: 27


Conditional deletion of pejvakin in adult outer hair cells causes progressive hearing loss in mice.

Harris SL, Kazmierczak M, Pangršič T, Shah P, Chuchvara N, Barrantes-Freer A, Moser T, Schwander M.

Neuroscience. 2017 Mar 6;344:380-393. doi: 10.1016/j.neuroscience.2016.12.055. Epub 2017 Jan 9.


Hair cell synaptic dysfunction, auditory fatigue and thermal sensitivity in otoferlin Ile515Thr mutants.

Strenzke N, Chakrabarti R, Al-Moyed H, Müller A, Hoch G, Pangrsic T, Yamanbaeva G, Lenz C, Pan KT, Auge E, Geiss-Friedlander R, Urlaub H, Brose N, Wichmann C, Reisinger E.

EMBO J. 2016 Dec 1;35(23):2519-2535. Epub 2016 Oct 11.


Tryptophan-rich basic protein (WRB) mediates insertion of the tail-anchored protein otoferlin and is required for hair cell exocytosis and hearing.

Vogl C, Panou I, Yamanbaeva G, Wichmann C, Mangosing SJ, Vilardi F, Indzhykulian AA, Pangršič T, Santarelli R, Rodriguez-Ballesteros M, Weber T, Jung S, Cardenas E, Wu X, Wojcik SM, Kwan KY, Del Castillo I, Schwappach B, Strenzke N, Corey DP, Lin SY, Moser T.

EMBO J. 2016 Dec 1;35(23):2536-2552. Epub 2016 Jul 25.


EF-hand protein Ca2+ buffers regulate Ca2+ influx and exocytosis in sensory hair cells.

Pangršič T, Gabrielaitis M, Michanski S, Schwaller B, Wolf F, Strenzke N, Moser T.

Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):E1028-37. doi: 10.1073/pnas.1416424112. Epub 2015 Feb 17.


Uniquantal release through a dynamic fusion pore is a candidate mechanism of hair cell exocytosis.

Chapochnikov NM, Takago H, Huang CH, Pangršič T, Khimich D, Neef J, Auge E, Göttfert F, Hell SW, Wichmann C, Wolf F, Moser T.

Neuron. 2014 Sep 17;83(6):1389-403. doi: 10.1016/j.neuron.2014.08.003. Epub 2014 Sep 4.


ATP hydrolysis is critically required for function of CaV1.3 channels in cochlear inner hair cells via fueling Ca2+ clearance.

Weiler S, Krinner S, Wong AB, Moser T, Pangršič T.

J Neurosci. 2014 May 14;34(20):6843-8. doi: 10.1523/JNEUROSCI.4990-13.2014.


Developmental refinement of hair cell synapses tightens the coupling of Ca2+ influx to exocytosis.

Wong AB, Rutherford MA, Gabrielaitis M, Pangrsic T, Göttfert F, Frank T, Michanski S, Hell S, Wolf F, Wichmann C, Moser T.

EMBO J. 2014 Feb 3;33(3):247-64. doi: 10.1002/embj.201387110. Epub 2014 Jan 17.


Modes and regulation of endocytic membrane retrieval in mouse auditory hair cells.

Neef J, Jung S, Wong AB, Reuter K, Pangrsic T, Chakrabarti R, Kügler S, Lenz C, Nouvian R, Boumil RM, Frankel WN, Wichmann C, Moser T.

J Neurosci. 2014 Jan 15;34(3):705-16. doi: 10.1523/JNEUROSCI.3313-13.2014.


Harmonin enhances voltage-dependent facilitation of Cav1.3 channels and synchronous exocytosis in mouse inner hair cells.

Gregory FD, Pangrsic T, Calin-Jageman IE, Moser T, Lee A.

J Physiol. 2013 Jul 1;591(13):3253-69. doi: 10.1113/jphysiol.2013.254367. Epub 2013 Apr 22.


Otoferlin: a multi-C2 domain protein essential for hearing.

Pangršič T, Reisinger E, Moser T.

Trends Neurosci. 2012 Nov;35(11):671-80. doi: 10.1016/j.tins.2012.08.002. Epub 2012 Sep 7. Review.


Molecular anatomy and physiology of exocytosis in sensory hair cells.

Rutherford MA, Pangršič T.

Cell Calcium. 2012 Sep-Oct;52(3-4):327-37. doi: 10.1016/j.ceca.2012.05.008. Epub 2012 Jun 6.


Harmonin inhibits presynaptic Cav1.3 Ca²⁺ channels in mouse inner hair cells.

Gregory FD, Bryan KE, Pangršič T, Calin-Jageman IE, Moser T, Lee A.

Nat Neurosci. 2011 Aug 7;14(9):1109-11. doi: 10.1038/nn.2895.


Exocytosis at the hair cell ribbon synapse apparently operates without neuronal SNARE proteins.

Nouvian R, Neef J, Bulankina AV, Reisinger E, Pangršič T, Frank T, Sikorra S, Brose N, Binz T, Moser T.

Nat Neurosci. 2011 Apr;14(4):411-3. doi: 10.1038/nn.2774. Epub 2011 Mar 6.


Bassoon and the synaptic ribbon organize Ca²+ channels and vesicles to add release sites and promote refilling.

Frank T, Rutherford MA, Strenzke N, Neef A, Pangršič T, Khimich D, Fejtova A, Gundelfinger ED, Liberman MC, Harke B, Bryan KE, Lee A, Egner A, Riedel D, Moser T.

Neuron. 2010 Nov 18;68(4):724-38. doi: 10.1016/j.neuron.2010.10.027. Erratum in: Neuron. 2010 Dec 22;68(6):1202. Fetjova, Anna [corrected to Fejtova, Anna].


Hearing requires otoferlin-dependent efficient replenishment of synaptic vesicles in hair cells.

Pangrsic T, Lasarow L, Reuter K, Takago H, Schwander M, Riedel D, Frank T, Tarantino LM, Bailey JS, Strenzke N, Brose N, Müller U, Reisinger E, Moser T.

Nat Neurosci. 2010 Jul;13(7):869-76. doi: 10.1038/nn.2578. Epub 2010 Jun 20.


Regulated exocytosis and vesicle trafficking in astrocytes.

Kreft M, Potokar M, Stenovec M, Pangrsic T, Zorec R.

Ann N Y Acad Sci. 2009 Jan;1152:30-42. doi: 10.1111/j.1749-6632.2008.04005.x. Review.


EAAT2 density at the astrocyte plasma membrane and Ca(2 + )-regulated exocytosis.

Stenovec M, Kreft M, Grilc S, Pangrsic T, Zorec R.

Mol Membr Biol. 2008 Apr;25(3):203-15. doi: 10.1080/09687680701790925.


Ca2+-dependent mobility of vesicles capturing anti-VGLUT1 antibodies.

Stenovec M, Kreft M, Grilc S, Potokar M, Kreft ME, Pangrsic T, Zorec R.

Exp Cell Res. 2007 Nov 1;313(18):3809-18. Epub 2007 Aug 31.


Exocytotic release of ATP from cultured astrocytes.

Pangrsic T, Potokar M, Stenovec M, Kreft M, Fabbretti E, Nistri A, Pryazhnikov E, Khiroug L, Giniatullin R, Zorec R.

J Biol Chem. 2007 Sep 28;282(39):28749-58. Epub 2007 Jul 12.


Cytoskeleton and vesicle mobility in astrocytes.

Potokar M, Kreft M, Li L, Daniel Andersson J, Pangrsic T, Chowdhury HH, Pekny M, Zorec R.

Traffic. 2007 Jan;8(1):12-20.


Astrocyte swelling leads to membrane unfolding, not membrane insertion.

Pangrsic T, Potokar M, Haydon PG, Zorec R, Kreft M.

J Neurochem. 2006 Oct;99(2):514-23.


FM1-43 measurements of local exocytotic events in rat melanotrophs.

Sikdar SK, Kreft M, Pangrsic T, Grilc S, Zorec R.

FEBS Lett. 2005 Dec 5;579(29):6575-80. Epub 2005 Nov 9.


Vesicle mobility studied in cultured astrocytes.

Potokar M, Kreft M, Pangrsic T, Zorec R.

Biochem Biophys Res Commun. 2005 Apr 8;329(2):678-83.


Light dependence of oxygen consumption by blowfly eyes recorded with a magnetic diver balance.

Pangrsic T, Stusek P, Belusic G, Zupancic G.

J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2005 Jan;191(1):75-84. Epub 2004 Nov 19.


Properties of Ca(2+)-dependent exocytosis in cultured astrocytes.

Kreft M, Stenovec M, Rupnik M, Grilc S, Krzan M, Potokar M, Pangrsic T, Haydon PG, Zorec R.

Glia. 2004 May;46(4):437-45.


Fusion-related release of glutamate from astrocytes.

Zhang Q, Pangrsic T, Kreft M, Krzan M, Li N, Sul JY, Halassa M, Van Bockstaele E, Zorec R, Haydon PG.

J Biol Chem. 2004 Mar 26;279(13):12724-33. Epub 2004 Jan 13.


Calcium-dependent exocytosis of atrial natriuretic peptide from astrocytes.

Krzan M, Stenovec M, Kreft M, Pangrsic T, Grilc S, Haydon PG, Zorec R.

J Neurosci. 2003 Mar 1;23(5):1580-3.

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