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Items: 1 to 50 of 225

1.

STING Signaling Promotes Inflammation in Experimental Acute Pancreatitis.

Zhao Q, Wei Y, Pandol SJ, Li L, Habtezion A.

Gastroenterology. 2018 Feb 6. pii: S0016-5085(18)30156-2. doi: 10.1053/j.gastro.2018.01.065. [Epub ahead of print]

PMID:
29425920
2.

Novel Small Molecule Inhibitors of Protein Kinase D Suppress NF-kappaB Activation and Attenuate the Severity of Rat Cerulein Pancreatitis.

Yuan J, Tan T, Geng M, Tan G, Chheda C, Pandol SJ.

Front Physiol. 2017 Dec 7;8:1014. doi: 10.3389/fphys.2017.01014. eCollection 2017.

3.

Alternation of Gut Microbiota in Patients with Pulmonary Tuberculosis.

Luo M, Liu Y, Wu P, Luo DX, Sun Q, Zheng H, Hu R, Pandol SJ, Li QF, Han YP, Zeng Y.

Front Physiol. 2017 Nov 17;8:822. doi: 10.3389/fphys.2017.00822. eCollection 2017.

4.

Tobacco and alcohol as risk factors for pancreatic cancer.

Korc M, Jeon CY, Edderkaoui M, Pandol SJ, Petrov MS; Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC).

Best Pract Res Clin Gastroenterol. 2017 Oct;31(5):529-536. doi: 10.1016/j.bpg.2017.09.001. Epub 2017 Sep 6. Review.

PMID:
29195672
5.

The Differential Role of Human Cationic Trypsinogen (PRSS1) p.R122H Mutation in Hereditary and Nonhereditary Chronic Pancreatitis: A Systematic Review and Meta-Analysis.

Hu C, Wen L, Deng L, Zhang C, Lugea A, Su HY, Waldron RT, Pandol SJ, Xia Q.

Gastroenterol Res Pract. 2017;2017:9505460. doi: 10.1155/2017/9505460. Epub 2017 Oct 8. Review.

6.

S-adenosylmethionine and methylthioadenosine inhibit cancer metastasis by targeting microRNA 34a/b-methionine adenosyltransferase 2A/2B axis.

Tomasi ML, Cossu C, Spissu Y, Floris A, Ryoo M, Iglesias-Ara A, Wang Q, Pandol SJ, Bhowmick NA, Seki E, Posadas EM, Lu SC.

Oncotarget. 2017 Aug 12;8(45):78851-78869. doi: 10.18632/oncotarget.20234. eCollection 2017 Oct 3.

7.

Uniting Epidemiology and Experimental Disease Models for Alcohol-Related Pancreatic Disease.

Setiawan VW, Monroe K, Lugea A, Yadav D, Pandol S.

Alcohol Res. 2017;38(2):173-182.

8.

Relationship between circulating levels of pancreatic proteolytic enzymes and pancreatic hormones.

Bharmal SH, Pendharkar SA, Singh RG, Goodarzi MO, Pandol SJ, Petrov MS.

Pancreatology. 2017 Nov - Dec;17(6):876-883. doi: 10.1016/j.pan.2017.09.007. Epub 2017 Sep 20.

PMID:
28958690
9.

Human Pancreatic Acinar Cells: Proteomic Characterization, Physiologic Responses, and Organellar Disorders in ex Vivo Pancreatitis.

Lugea A, Waldron RT, Mareninova OA, Shalbueva N, Deng N, Su HY, Thomas DD, Jones EK, Messenger SW, Yang J, Hu C, Gukovsky I, Liu Z, Groblewski GE, Gukovskaya AS, Gorelick FS, Pandol SJ.

Am J Pathol. 2017 Dec;187(12):2726-2743. doi: 10.1016/j.ajpath.2017.08.017. Epub 2017 Sep 19.

PMID:
28935577
10.

Diabetes Mellitus and Obesity as Risk Factors for Pancreatic Cancer.

Eibl G, Cruz-Monserrate Z, Korc M, Petrov MS, Goodarzi MO, Fisher WE, Habtezion A, Lugea A, Pandol SJ, Hart PA, Andersen DK; Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer.

J Acad Nutr Diet. 2017 Sep 11. pii: S2212-2672(17)31087-0. doi: 10.1016/j.jand.2017.07.005. [Epub ahead of print]

PMID:
28919082
11.

Incidence of pancreatic cancer is dramatically increased by a high fat, high calorie diet in KrasG12D mice.

Chang HH, Moro A, Takakura K, Su HY, Mo A, Nakanishi M, Waldron RT, French SW, Dawson DW, Hines OJ, Li G, Go VLW, Sinnett-Smith J, Pandol SJ, Lugea A, Gukovskaya AS, Duff MO, Rosenberg DW, Rozengurt E, Eibl G.

PLoS One. 2017 Sep 8;12(9):e0184455. doi: 10.1371/journal.pone.0184455. eCollection 2017.

12.

M2-like macrophages in the fibrotic liver protect mice against lethal insults through conferring apoptosis resistance to hepatocytes.

Bai L, Liu X, Zheng Q, Kong M, Zhang X, Hu R, Lou J, Ren F, Chen Y, Zheng S, Liu S, Han YP, Duan Z, Pandol SJ.

Sci Rep. 2017 Sep 5;7(1):10518. doi: 10.1038/s41598-017-11303-z.

13.

The Combination of Alcohol and Cigarette Smoke Induces Endoplasmic Reticulum Stress and Cell Death in Pancreatic Acinar Cells.

Lugea A, Gerloff A, Su HY, Xu Z, Go A, Hu C, French SW, Wilson JS, Apte MV, Waldron RT, Pandol SJ.

Gastroenterology. 2017 Dec;153(6):1674-1686. doi: 10.1053/j.gastro.2017.08.036. Epub 2017 Aug 25.

PMID:
28847752
14.

Effect of Serum Triglycerides on Clinical Outcomes in Acute Pancreatitis: Findings From a Regional Integrated Health Care System.

Sue LY, Batech M, Yadav D, Pandol SJ, Blumentals WA, von Krusenstiern LS, Chen W, Wu BU.

Pancreas. 2017 Aug;46(7):874-879. doi: 10.1097/MPA.0000000000000860.

PMID:
28697126
15.

The Potential for Circulating Tumor Cells in Pancreatic Cancer Management.

Pimienta M, Edderkaoui M, Wang R, Pandol S.

Front Physiol. 2017 Jun 2;8:381. doi: 10.3389/fphys.2017.00381. eCollection 2017. Review.

16.

Chronic Pancreatitis: Current Status and Challenges for Prevention and Treatment.

Lew D, Afghani E, Pandol S.

Dig Dis Sci. 2017 Jul;62(7):1702-1712. doi: 10.1007/s10620-017-4602-2. Epub 2017 May 13. Review.

17.

Dynamic Measurement of Disease Activity in Acute Pancreatitis: The Pancreatitis Activity Scoring System.

Wu BU, Batech M, Quezada M, Lew D, Fujikawa K, Kung J, Jamil LH, Chen W, Afghani E, Reicher S, Buxbaum J, Pandol SJ.

Am J Gastroenterol. 2017 Jul;112(7):1144-1152. doi: 10.1038/ajg.2017.114. Epub 2017 May 2.

18.

Cationic Polystyrene Resolves Nonalcoholic Steatohepatitis, Obesity, and Metabolic Disorders by Promoting Eubiosis of Gut Microbiota and Decreasing Endotoxemia.

Zhu A, Chen J, Wu P, Luo M, Zeng Y, Liu Y, Zheng H, Zhang L, Chen Z, Sun Q, Li W, Duan Y, Su D, Xiao Z, Duan Z, Zheng S, Bai L, Zhang X, Ju Z, Li Y, Hu R, Pandol SJ, Han YP.

Diabetes. 2017 Aug;66(8):2137-2143. doi: 10.2337/db17-0070. Epub 2017 Apr 26.

19.

Type 3c (pancreatogenic) diabetes mellitus secondary to chronic pancreatitis and pancreatic cancer.

Hart PA, Bellin MD, Andersen DK, Bradley D, Cruz-Monserrate Z, Forsmark CE, Goodarzi MO, Habtezion A, Korc M, Kudva YC, Pandol SJ, Yadav D, Chari ST; Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer(CPDPC).

Lancet Gastroenterol Hepatol. 2016 Nov;1(3):226-237. doi: 10.1016/S2468-1253(16)30106-6. Epub 2016 Oct 12. Review.

20.

Reply.

Setiawan VW, Monroe KR, Pandol SJ.

Clin Gastroenterol Hepatol. 2017 Jul;15(7):1139. doi: 10.1016/j.cgh.2017.03.036. Epub 2017 Apr 2. No abstract available.

21.

Academic Pancreas Centers of Excellence: Guidance from a multidisciplinary chronic pancreatitis working group at PancreasFest.

Sheth SG, Conwell DL, Whitcomb DC, Alsante M, Anderson MA, Barkin J, Brand R, Cote GA, Freedman SD, Gelrud A, Gorelick F, Lee LS, Morgan K, Pandol S, Singh VK, Yadav D, Wilcox CM, Hart PA.

Pancreatology. 2017 May - Jun;17(3):419-430. doi: 10.1016/j.pan.2017.02.015. Epub 2017 Feb 28.

22.

Sphincter of Oddi Function and Risk Factors for Dysfunction.

Afghani E, Lo SK, Covington PS, Cash BD, Pandol SJ.

Front Nutr. 2017 Jan 30;4:1. doi: 10.3389/fnut.2017.00001. eCollection 2017. Review.

23.

Cathepsin H-Mediated Degradation of HDAC4 for Matrix Metalloproteinase Expression in Hepatic Stellate Cells: Implications of Epigenetic Suppression of Matrix Metalloproteinases in Fibrosis through Stabilization of Class IIa Histone Deacetylases.

Yang Z, Liu Y, Qin L, Wu P, Xia Z, Luo M, Zeng Y, Tsukamoto H, Ju Z, Su D, Kang H, Xiao Z, Zheng S, Duan Z, Hu R, Wang Q, Pandol SJ, Han YP.

Am J Pathol. 2017 Apr;187(4):781-797. doi: 10.1016/j.ajpath.2016.12.001. Epub 2017 Feb 1.

PMID:
28157489
24.

Vitamin D Signaling through Induction of Paneth Cell Defensins Maintains Gut Microbiota and Improves Metabolic Disorders and Hepatic Steatosis in Animal Models.

Su D, Nie Y, Zhu A, Chen Z, Wu P, Zhang L, Luo M, Sun Q, Cai L, Lai Y, Xiao Z, Duan Z, Zheng S, Wu G, Hu R, Tsukamoto H, Lugea A, Liu Z, Pandol SJ, Han YP.

Front Physiol. 2016 Nov 15;7:498. eCollection 2016.

25.

Cadherin-11 Is a Cell Surface Marker Up-Regulated in Activated Pancreatic Stellate Cells and Is Involved in Pancreatic Cancer Cell Migration.

Birtolo C, Pham H, Morvaridi S, Chheda C, Go VL, Ptasznik A, Edderkaoui M, Weisman MH, Noss E, Brenner MB, Larson B, Guindi M, Wang Q, Pandol SJ.

Am J Pathol. 2017 Jan;187(1):146-155. doi: 10.1016/j.ajpath.2016.09.012. Epub 2016 Nov 14.

26.

Aryl Hydrocarbon Receptor Ligands in Cigarette Smoke Induce Production of Interleukin-22 to Promote Pancreatic Fibrosis in Models of Chronic Pancreatitis.

Xue J, Zhao Q, Sharma V, Nguyen LP, Lee YN, Pham KL, Edderkaoui M, Pandol SJ, Park W, Habtezion A.

Gastroenterology. 2016 Dec;151(6):1206-1217. doi: 10.1053/j.gastro.2016.09.064. Epub 2016 Oct 18.

27.

Dietary Factors Reduce Risk of Acute Pancreatitis in a Large Multiethnic Cohort.

Setiawan VW, Pandol SJ, Porcel J, Wei PC, Wilkens LR, Le Marchand L, Pike MC, Monroe KR.

Clin Gastroenterol Hepatol. 2017 Feb;15(2):257-265.e3. doi: 10.1016/j.cgh.2016.08.038. Epub 2016 Sep 5.

28.

Cultured circulating tumor cells and their derived xenografts for personalized oncology.

Wang R, Chu GCY, Mrdenovic S, Annamalai AA, Hendifar AE, Nissen NN, Tomlinson JS, Lewis M, Palanisamy N, Tseng HR, Posadas EM, Freeman MR, Pandol SJ, Zhau HE, Chung LWK.

Asian J Urol. 2016 Oct;3(4):240-253. doi: 10.1016/j.ajur.2016.08.005. Epub 2016 Aug 25. Review.

29.

Essential Role of Lyn in Fibrosis.

Pham H, Birtolo C, Chheda C, Yang W, Rodriguez MD, Liu ST, Gugliotta G, Lewis MS, Cirulli V, Pandol SJ, Ptasznik A.

Front Physiol. 2016 Aug 31;7:387. doi: 10.3389/fphys.2016.00387. eCollection 2016.

30.

Insulin promotes proliferation and fibrosing responses in activated pancreatic stellate cells.

Yang J, Waldron RT, Su HY, Moro A, Chang HH, Eibl G, Ferreri K, Kandeel FR, Lugea A, Li L, Pandol SJ.

Am J Physiol Gastrointest Liver Physiol. 2016 Oct 1;311(4):G675-G687. doi: 10.1152/ajpgi.00251.2016. Epub 2016 Sep 8.

31.

Acceleration of our understanding of recurrent acute and chronic pancreatitis.

Pandol SJ, Forsmark CE, Hart PA; Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC).

Pancreatology. 2016 Sep-Oct;16(5):692-3. doi: 10.1016/j.pan.2016.08.002. Epub 2016 Aug 10. No abstract available.

32.

New insights into the pathways initiating and driving pancreatitis.

Gukovskaya AS, Pandol SJ, Gukovsky I.

Curr Opin Gastroenterol. 2016 Jul 13. [Epub ahead of print]

33.

A bitter pill for type 2 diabetes? The activation of bitter taste receptor TAS2R38 can stimulate GLP-1 release from enteroendocrine L-cells.

Pham H, Hui H, Morvaridi S, Cai J, Zhang S, Tan J, Wu V, Levin N, Knudsen B, Goddard WA 3rd, Pandol SJ, Abrol R.

Biochem Biophys Res Commun. 2016 Jul 1;475(3):295-300. doi: 10.1016/j.bbrc.2016.04.149. Epub 2016 May 18.

34.

Prospective Study of Alcohol Drinking, Smoking, and Pancreatitis: The Multiethnic Cohort.

Setiawan VW, Pandol SJ, Porcel J, Wilkens LR, Le Marchand L, Pike MC, Monroe KR.

Pancreas. 2016 Jul;45(6):819-25. doi: 10.1097/MPA.0000000000000657.

35.

Therapy of pancreatic cancer via an EphA2 receptor-targeted delivery of gemcitabine.

Quinn BA, Wang S, Barile E, Das SK, Emdad L, Sarkar D, De SK, Morvaridi SK, Stebbins JL, Pandol SJ, Fisher PB, Pellecchia M.

Oncotarget. 2016 Mar 29;7(13):17103-10. doi: 10.18632/oncotarget.7931.

36.

Exosome Migration Inhibitory Factor as a Marker and Therapeutic Target for Pancreatic Cancer.

Matsushita H, Yang YM, Pandol SJ, Seki E.

Gastroenterology. 2016 Apr;150(4):1033-5. doi: 10.1053/j.gastro.2016.02.051. Epub 2016 Feb 27. No abstract available.

37.

PKD signaling and pancreatitis.

Yuan J, Pandol SJ.

J Gastroenterol. 2016 Jul;51(7):651-9. doi: 10.1007/s00535-016-1175-3. Epub 2016 Feb 15. Review.

38.

The Unfolded Protein Response Plays a Predominant Homeostatic Role in Response to Mitochondrial Stress in Pancreatic Stellate Cells.

Su HY, Waldron RT, Gong R, Ramanujan VK, Pandol SJ, Lugea A.

PLoS One. 2016 Feb 5;11(2):e0148999. doi: 10.1371/journal.pone.0148999. eCollection 2016.

39.

HDAC3 mediates smoking-induced pancreatic cancer.

Edderkaoui M, Xu S, Chheda C, Morvaridi S, Hu RW, Grippo PJ, Mascariñas E, Principe DR, Knudsen B, Xue J, Habtezion A, Uyeminami D, Pinkerton KE, Pandol SJ.

Oncotarget. 2016 Feb 16;7(7):7747-60. doi: 10.18632/oncotarget.6820.

40.

Macrophages and pancreatic ductal adenocarcinoma.

Habtezion A, Edderkaoui M, Pandol SJ.

Cancer Lett. 2016 Oct 10;381(1):211-6. doi: 10.1016/j.canlet.2015.11.049. Epub 2015 Dec 18. Review.

41.

Phosphatidylinositol 3-Kinase: A Link Between Inflammation and Pancreatic Cancer.

Birtolo C, Go VL, Ptasznik A, Eibl G, Pandol SJ.

Pancreas. 2016 Jan;45(1):21-31. doi: 10.1097/MPA.0000000000000531. Review.

42.

Alcoholic hepatitis: The pivotal role of Kupffer cells.

Suraweera DB, Weeratunga AN, Hu RW, Pandol SJ, Hu R.

World J Gastrointest Pathophysiol. 2015 Nov 15;6(4):90-8. doi: 10.4291/wjgp.v6.i4.90.

43.

Role of YAP and TAZ in pancreatic ductal adenocarcinoma and in stellate cells associated with cancer and chronic pancreatitis.

Morvaridi S, Dhall D, Greene MI, Pandol SJ, Wang Q.

Sci Rep. 2015 Nov 16;5:16759. doi: 10.1038/srep16759.

44.

Acute Pancreatitis-Progress and Challenges: A Report on an International Symposium.

Afghani E, Pandol SJ, Shimosegawa T, Sutton R, Wu BU, Vege SS, Gorelick F, Hirota M, Windsor J, Lo SK, Freeman ML, Lerch MM, Tsuji Y, Melmed GY, Wassef W, Mayerle J.

Pancreas. 2015 Nov;44(8):1195-210. doi: 10.1097/MPA.0000000000000500.

45.

Impact of statin use on survival in patients undergoing resection for early-stage pancreatic cancer.

Wu BU, Chang J, Jeon CY, Pandol SJ, Huang B, Ngor EW, Difronzo AL, Cooper RM.

Am J Gastroenterol. 2015 Aug;110(8):1233-9. doi: 10.1038/ajg.2015.217. Epub 2015 Jul 21.

46.

Characterization of Mouse Models of Early Pancreatic Lesions Induced by Alcohol and Chronic Pancreatitis.

Xu S, Chheda C, Ouhaddi Y, Benhaddou H, Bourhim M, Grippo PJ, Principe DR, Mascariñas E, DeCant B, Tsukamoto H, Pandol SJ, Edderkaoui M.

Pancreas. 2015 Aug;44(6):882-7. doi: 10.1097/MPA.0000000000000380.

47.

Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP.

Mukherjee R, Mareninova OA, Odinokova IV, Huang W, Murphy J, Chvanov M, Javed MA, Wen L, Booth DM, Cane MC, Awais M, Gavillet B, Pruss RM, Schaller S, Molkentin JD, Tepikin AV, Petersen OH, Pandol SJ, Gukovsky I, Criddle DN, Gukovskaya AS, Sutton R; NIHR Pancreas Biomedical Research Unit.

Gut. 2016 Aug;65(8):1333-46. doi: 10.1136/gutjnl-2014-308553. Epub 2015 Jun 12.

48.

What are the macrophages and stellate cells doing in pancreatic adenocarcinoma?

Pandol SJ, Edderkaoui M.

Front Physiol. 2015 May 15;6:125. doi: 10.3389/fphys.2015.00125. eCollection 2015. Review.

49.

Correction: The Association of Statin Use after Cancer Diagnosis with Survival in Pancreatic Cancer Patients: A SEER-Medicare Analysis.

Jeon CY, Pandol SJ, Wu B, Cook-Wiens G, Gottlieb RA, Bairey Merz CN, Goodman MT.

PLoS One. 2015 May 27;10(5):e0128730. doi: 10.1371/journal.pone.0128730. eCollection 2015. No abstract available.

50.

Alternatively activated macrophages promote pancreatic fibrosis in chronic pancreatitis.

Xue J, Sharma V, Hsieh MH, Chawla A, Murali R, Pandol SJ, Habtezion A.

Nat Commun. 2015 May 18;6:7158. doi: 10.1038/ncomms8158.

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