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Items: 1 to 50 of 60

1.

The LAM Lung Cell and Its Human Cell Models.

Steagall WK, Pacheco-Rodriguez G, Darling TN, Torre O, Harari S, Moss J.

Am J Respir Cell Mol Biol. 2018 Feb 6. doi: 10.1165/rcmb.2017-0403TR. [Epub ahead of print]

PMID:
29406787
2.

Effect of beta-agonists on LAM progression and treatment.

Le K, Steagall WK, Stylianou M, Pacheco-Rodriguez G, Darling TN, Vaughan M, Moss J.

Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E944-E953. doi: 10.1073/pnas.1719960115. Epub 2018 Jan 16.

PMID:
29339522
3.

BRAF and NRAS mutations in circulating Langerhans-like CD1a+ cells in a patient with pulmonary Langerhans' cell histiocytosis.

Zhang L, Pacheco-Rodriguez G, Steagall WK, Kato J, Colby TV, Haughey M, Moss J.

Eur Respir J. 2017 Oct 12;50(4). pii: 1700521. doi: 10.1183/13993003.00521-2017. Print 2017 Oct. No abstract available.

PMID:
29025887
4.

TRIM23 mediates virus-induced autophagy via activation of TBK1.

Sparrer KMJ, Gableske S, Zurenski MA, Parker ZM, Full F, Baumgart GJ, Kato J, Pacheco-Rodriguez G, Liang C, Pornillos O, Moss J, Vaughan M, Gack MU.

Nat Microbiol. 2017 Nov;2(11):1543-1557. doi: 10.1038/s41564-017-0017-2. Epub 2017 Sep 4.

5.

CA-125 in Disease Progression and Treatment of Lymphangioleiomyomatosis.

Glasgow CG, Pacheco-Rodriguez G, Steagall WK, Haughey ME, Julien-Williams PA, Stylianou MP, Gochuico BR, Moss J.

Chest. 2018 Feb;153(2):339-348. doi: 10.1016/j.chest.2017.05.018. Epub 2017 May 30.

PMID:
28576630
6.

Aberrant SYK Kinase Signaling Is Essential for Tumorigenesis Induced by TSC2 Inactivation.

Cui Y, Steagall WK, Lamattina AM, Pacheco-Rodriguez G, Stylianou M, Kidambi P, Stump B, Golzarri F, Rosas IO, Priolo C, Henske EP, Moss J, El-Chemaly S.

Cancer Res. 2017 Mar 15;77(6):1492-1502. doi: 10.1158/0008-5472.CAN-16-2755. Epub 2017 Feb 15.

7.

Benign Metastasizing Leiomyoma.

Pacheco-Rodriguez G, Taveira-DaSilva AM, Moss J.

Clin Chest Med. 2016 Sep;37(3):589-95. doi: 10.1016/j.ccm.2016.04.019. Epub 2016 Jun 25. Review.

PMID:
27514603
8.

Genetic heterogeneity of circulating cells from patients with lymphangioleiomyomatosis with and without lung transplantation.

Steagall WK, Zhang L, Cai X, Pacheco-Rodriguez G, Moss J.

Am J Respir Crit Care Med. 2015 Apr 1;191(7):854-6. doi: 10.1164/rccm.201412-2170LE. No abstract available.

9.

Tuberous sclerosis complex 2 loss of heterozygosity in patients with lung disease and cancer.

Zhang L, Pacheco-Rodriguez G, Steagall WK, Kato J, Haughey M, Fontana JR, Manganiello VC, Moss J.

Am J Respir Crit Care Med. 2015 Feb 1;191(3):352-5. doi: 10.1164/rccm.201408-1480LE. No abstract available.

10.

Antibody αPEP13h reacts with lymphangioleiomyomatosis cells in lung nodules.

Valencia JC, Steagall WK, Zhang Y, Fetsch P, Abati A, Tsukada K, Billings E, Hearing VJ, Yu ZX, Pacheco-Rodriguez G, Moss J.

Chest. 2015 Mar;147(3):771-777. doi: 10.1378/chest.14-0380.

11.

Electrophoretic characterization of the Mammalian nuclear matrix proteome, nuclear envelope, nucleoli and covalently bound ADP-ribose polymers: potential applications to cancer.

Aranda XG, Racho RG, Pacheco-Rodríguez G, Alvarez-González R.

Cancer Genomics Proteomics. 2014 Sep-Oct;11(5):217-23.

PMID:
25331794
12.

Nuclear localization of vascular endothelial growth factor-D and regulation of c-Myc-dependent transcripts in human lung fibroblasts.

El-Chemaly S, Pacheco-Rodriguez G, Malide D, Meza-Carmen V, Kato J, Cui Y, Padilla PI, Samidurai A, Gochuico BR, Moss J.

Am J Respir Cell Mol Biol. 2014 Jul;51(1):34-42. doi: 10.1165/rcmb.2013-0417OC.

13.

Sirolimus decreases circulating lymphangioleiomyomatosis cells in patients with lymphangioleiomyomatosis.

Cai X, Pacheco-Rodriguez G, Haughey M, Samsel L, Xu S, Wu HP, McCoy JP, Stylianou M, Darling TN, Moss J.

Chest. 2014 Jan;145(1):108-112. doi: 10.1378/chest.13-1071.

14.

Sex-specific lung diseases: effect of oestrogen on cultured cells and in animal models.

Shim B, Pacheco-Rodriguez G, Kato J, Darling TN, Vaughan M, Moss J.

Eur Respir Rev. 2013 Sep 1;22(129):302-11. doi: 10.1183/09059180.00002813. Review.

15.

Osteoprotegerin contributes to the metastatic potential of cells with a dysfunctional TSC2 tumor-suppressor gene.

Steagall WK, Pacheco-Rodriguez G, Glasgow CG, Ikeda Y, Lin JP, Zheng G, Moss J.

Am J Pathol. 2013 Sep;183(3):938-50. doi: 10.1016/j.ajpath.2013.05.024. Epub 2013 Jul 16.

16.

Pulmonary lymphangiomatosis.

Satria MN, Pacheco-Rodriguez G, Moss J.

Lymphat Res Biol. 2011;9(4):191-3. doi: 10.1089/lrb.2011.0023.

17.

Regulation of growth factor receptor degradation by ADP-ribosylation factor domain protein (ARD) 1.

Meza-Carmen V, Pacheco-Rodriguez G, Kang GS, Kato J, Donati C, Zhang CY, Vichi A, Payne DM, El-Chemaly S, Stylianou M, Moss J, Vaughan M.

Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10454-9. doi: 10.1073/pnas.1103867108. Epub 2011 Jun 8.

18.

Erythropoietin-driven proliferation of cells with mutations in the tumor suppressor gene TSC2.

Ikeda Y, Taveira-DaSilva AM, Pacheco-Rodriguez G, Steagall WK, El-Chemaly S, Gochuico BR, May RM, Hathaway OM, Li S, Wang JA, Darling TN, Stylianou M, Moss J.

Am J Physiol Lung Cell Mol Physiol. 2011 Jan;300(1):L64-72. doi: 10.1152/ajplung.00095.2010. Epub 2010 Oct 29.

19.

The role of chemokines in migration of metastatic-like lymphangioleiomyomatosis cells.

Pacheco-Rodriguez G, Moss J.

Crit Rev Immunol. 2010;30(4):387-94. Review.

20.

Lymphangioleiomyomatosis (LAM): molecular insights lead to targeted therapies.

Glasgow CG, Steagall WK, Taveira-Dasilva A, Pacheco-Rodriguez G, Cai X, El-Chemaly S, Moses M, Darling T, Moss J.

Respir Med. 2010 Jul;104 Suppl 1:S45-58. doi: 10.1016/j.rmed.2010.03.017.

21.

Phenotypic characterization of disseminated cells with TSC2 loss of heterozygosity in patients with lymphangioleiomyomatosis.

Cai X, Pacheco-Rodriguez G, Fan QY, Haughey M, Samsel L, El-Chemaly S, Wu HP, McCoy JP, Steagall WK, Lin JP, Darling TN, Moss J.

Am J Respir Crit Care Med. 2010 Dec 1;182(11):1410-8. doi: 10.1164/rccm.201003-0489OC. Epub 2010 Jul 16.

22.

Effects of prolactin on TSC2-null Eker rat cells and in pulmonary lymphangioleiomyomatosis.

Terasaki Y, Yahiro K, Pacheco-Rodriguez G, Steagall WK, Stylianou MP, Evans JF, Walker AM, Moss J.

Am J Respir Crit Care Med. 2010 Aug 15;182(4):531-9. doi: 10.1164/rccm.200911-1737OC. Epub 2010 Apr 22.

23.

Lymphangioleiomyomatosis and TSC2-/- cells.

Darling TN, Pacheco-Rodriguez G, Gorio A, Lesma E, Walker C, Moss J.

Lymphat Res Biol. 2010 Mar;8(1):59-69. doi: 10.1089/lrb.2009.0031. Review.

24.

The natural history of lymphangioleiomyomatosis: markers of severity, rate of progression and prognosis.

Taveira-DaSilva AM, Pacheco-Rodriguez G, Moss J.

Lymphat Res Biol. 2010 Mar;8(1):9-19. doi: 10.1089/lrb.2009.0024.

25.

Involvement of lymphatics in lymphangioleiomyomatosis.

Glasgow CG, Taveira-DaSilva A, Pacheco-Rodriguez G, Steagall WK, Tsukada K, Cai X, El-Chemaly S, Moss J.

Lymphat Res Biol. 2009 Dec;7(4):221-8. doi: 10.1089/lrb.2009.0017.

26.

Lymphatics in idiopathic pulmonary fibrosis: new insights into an old disease.

El-Chemaly S, Pacheco-Rodriguez G, Ikeda Y, Malide D, Moss J.

Lymphat Res Biol. 2009 Dec;7(4):197-203. doi: 10.1089/lrb.2009.0014. Review.

27.

Interaction of phosphodiesterase 3A with brefeldin A-inhibited guanine nucleotide-exchange proteins BIG1 and BIG2 and effect on ARF1 activity.

Puxeddu E, Uhart M, Li CC, Ahmad F, Pacheco-Rodriguez G, Manganiello VC, Moss J, Vaughan M.

Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6158-63. doi: 10.1073/pnas.0901558106. Epub 2009 Mar 30.

28.

Abnormal lymphangiogenesis in idiopathic pulmonary fibrosis with insights into cellular and molecular mechanisms.

El-Chemaly S, Malide D, Zudaire E, Ikeda Y, Weinberg BA, Pacheco-Rodriguez G, Rosas IO, Aparicio M, Ren P, MacDonald SD, Wu HP, Nathan SD, Cuttitta F, McCoy JP, Gochuico BR, Moss J.

Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3958-63. doi: 10.1073/pnas.0813368106. Epub 2009 Feb 23.

29.

Chemokine-enhanced chemotaxis of lymphangioleiomyomatosis cells with mutations in the tumor suppressor TSC2 gene.

Pacheco-Rodriguez G, Kumaki F, Steagall WK, Zhang Y, Ikeda Y, Lin JP, Billings EM, Moss J.

J Immunol. 2009 Feb 1;182(3):1270-7.

30.

Calcitonin gene-related peptide receptor expression in alternatively activated monocytes/macrophages during irreversible pulpitis.

Caviedes-Bucheli J, Moreno GC, López MP, Bermeo-Noguera AM, Pacheco-Rodríguez G, Cuellar A, Muñoz HR.

J Endod. 2008 Aug;34(8):945-9. doi: 10.1016/j.joen.2008.05.011.

PMID:
18634925
31.

Association of guanine nucleotide-exchange protein BIG1 in HepG2 cell nuclei with nucleolin, U3 snoRNA, and fibrillarin.

Padilla PI, Uhart M, Pacheco-Rodriguez G, Peculis BA, Moss J, Vaughan M.

Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3357-61. doi: 10.1073/pnas.0712387105. Epub 2008 Feb 21.

32.

Mesenchymal-epithelial interactions involving epiregulin in tuberous sclerosis complex hamartomas.

Li S, Takeuchi F, Wang JA, Fan Q, Komurasaki T, Billings EM, Pacheco-Rodriguez G, Moss J, Darling TN.

Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3539-44. doi: 10.1073/pnas.0712397105. Epub 2008 Feb 21.

33.

Unfolded protein response and cell death after depletion of brefeldin A-inhibited guanine nucleotide-exchange protein GBF1.

Citterio C, Vichi A, Pacheco-Rodriguez G, Aponte AM, Moss J, Vaughan M.

Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2877-82. doi: 10.1073/pnas.0712224105. Epub 2008 Feb 14.

34.

TSC2 loss in lymphangioleiomyomatosis cells correlated with expression of CD44v6, a molecular determinant of metastasis.

Pacheco-Rodriguez G, Steagall WK, Crooks DM, Stevens LA, Hashimoto H, Li S, Wang JA, Darling TN, Moss J.

Cancer Res. 2007 Nov 1;67(21):10573-81.

35.

ARL4D recruits cytohesin-2/ARNO to modulate actin remodeling.

Li CC, Chiang TC, Wu TS, Pacheco-Rodriguez G, Moss J, Lee FJ.

Mol Biol Cell. 2007 Nov;18(11):4420-37. Epub 2007 Sep 5.

36.

Association of brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BIG2) with recycling endosomes during transferrin uptake.

Shen X, Xu KF, Fan Q, Pacheco-Rodriguez G, Moss J, Vaughan M.

Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2635-40. Epub 2006 Feb 13.

37.

Tissue-specific renin-angiotensin system in pulmonary lymphangioleiomyomatosis.

Valencia JC, Pacheco-Rodriguez G, Carmona AK, Xavier J, Bruneval P, Riemenschneider WK, Ikeda Y, Yu ZX, Ferrans VJ, Moss J.

Am J Respir Cell Mol Biol. 2006 Jul;35(1):40-7. Epub 2006 Feb 10.

38.

Effect of protein kinase A on accumulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) in HepG2 cell nuclei.

Citterio C, Jones HD, Pacheco-Rodriguez G, Islam A, Moss J, Vaughan M.

Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2683-8. Epub 2006 Feb 8.

39.

Cytohesin-1: structure, function, and ARF activation.

Pacheco-Rodriguez G, Moss J, Vaughan M.

Methods Enzymol. 2005;404:184-95.

PMID:
16413269
40.

MCP-1 overexpressed in tuberous sclerosis lesions acts as a paracrine factor for tumor development.

Li S, Takeuchi F, Wang JA, Fuller C, Pacheco-Rodriguez G, Moss J, Darling TN.

J Exp Med. 2005 Sep 5;202(5):617-24. Epub 2005 Aug 29.

42.

Interaction of BIG2, a brefeldin A-inhibited guanine nucleotide-exchange protein, with exocyst protein Exo70.

Xu KF, Shen X, Li H, Pacheco-Rodriguez G, Moss J, Vaughan M.

Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):2784-9. Epub 2005 Feb 10.

43.

E3 ubiquitin ligase activity of the trifunctional ARD1 (ADP-ribosylation factor domain protein 1).

Vichi A, Payne DM, Pacheco-Rodriguez G, Moss J, Vaughan M.

Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):1945-50. Epub 2005 Jan 31.

44.

Molecular and genetic analysis of disseminated neoplastic cells in lymphangioleiomyomatosis.

Crooks DM, Pacheco-Rodriguez G, DeCastro RM, McCoy JP Jr, Wang JA, Kumaki F, Darling T, Moss J.

Proc Natl Acad Sci U S A. 2004 Dec 14;101(50):17462-7. Epub 2004 Dec 6.

45.

Nuclear localization and molecular partners of BIG1, a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP-ribosylation factors.

Padilla PI, Pacheco-Rodriguez G, Moss J, Vaughan M.

Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):2752-7. Epub 2004 Feb 18.

46.

Interaction of FK506-binding protein 13 with brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1): effects of FK506.

Padilla PI, Chang MJ, Pacheco-Rodriguez G, Adamik R, Moss J, Vaughan M.

Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2322-7. Epub 2003 Feb 26.

47.

Protein kinase A-anchoring (AKAP) domains in brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BIG2).

Li H, Adamik R, Pacheco-Rodriguez G, Moss J, Vaughan M.

Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1627-32. Epub 2003 Feb 5.

48.

ARF-directed guanine-nucleotide-exchange (GEP) proteins.

Pacheco-Rodriguez G, Moss J, Vaughan M.

Methods Mol Biol. 2002;189:181-9. No abstract available.

PMID:
12094586
49.

Giles F. Filley Lecture. Genetics and gene expression in lymphangioleiomyomatosis.

Pacheco-Rodriguez G, Kristof AS, Stevens LA, Zhang Y, Crooks D, Moss J.

Chest. 2002 Mar;121(3 Suppl):56S-60S.

PMID:
11893686
50.

BIG1 and BIG2: brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors.

Pacheco-Rodriguez G, Moss J, Vaughan M.

Methods Enzymol. 2002;345:397-404. No abstract available.

PMID:
11665623

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