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Items: 23

1.

Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening.

Verissimo CS, Overmeer RM, Ponsioen B, Drost J, Mertens S, Verlaan-Klink I, Gerwen BV, van der Ven M, Wetering MV, Egan DA, Bernards R, Clevers H, Bos JL, Snippert HJ.

Elife. 2016 Nov 15;5. pii: e18489. doi: 10.7554/eLife.18489.

2.

Sequential cancer mutations in cultured human intestinal stem cells.

Drost J, van Jaarsveld RH, Ponsioen B, Zimberlin C, van Boxtel R, Buijs A, Sachs N, Overmeer RM, Offerhaus GJ, Begthel H, Korving J, van de Wetering M, Schwank G, Logtenberg M, Cuppen E, Snippert HJ, Medema JP, Kops GJ, Clevers H.

Nature. 2015 May 7;521(7550):43-7. doi: 10.1038/nature14415. Epub 2015 Apr 29.

PMID:
25924068
3.

DNA damage response and transcription.

Lagerwerf S, Vrouwe MG, Overmeer RM, Fousteri MI, Mullenders LH.

DNA Repair (Amst). 2011 Jul 15;10(7):743-50. doi: 10.1016/j.dnarep.2011.04.024. Epub 2011 May 31. Review.

PMID:
21622031
4.

Combined promoter methylation analysis of CADM1 and MAL: an objective triage tool for high-risk human papillomavirus DNA-positive women.

Hesselink AT, Heideman DA, Steenbergen RD, Coupé VM, Overmeer RM, Rijkaart D, Berkhof J, Meijer CJ, Snijders PJ.

Clin Cancer Res. 2011 Apr 15;17(8):2459-65. doi: 10.1158/1078-0432.CCR-10-2548. Epub 2011 Mar 9.

5.

Replication protein A safeguards genome integrity by controlling NER incision events.

Overmeer RM, Moser J, Volker M, Kool H, Tomkinson AE, van Zeeland AA, Mullenders LH, Fousteri M.

J Cell Biol. 2011 Feb 7;192(3):401-15. doi: 10.1083/jcb.201006011. Epub 2011 Jan 31.

6.

UV-induced photolesions elicit ATR-kinase-dependent signaling in non-cycling cells through nucleotide excision repair-dependent and -independent pathways.

Vrouwe MG, Pines A, Overmeer RM, Hanada K, Mullenders LH.

J Cell Sci. 2011 Feb 1;124(Pt 3):435-46. doi: 10.1242/jcs.075325. Epub 2011 Jan 11.

7.

Combined CADM1 and MAL promoter methylation analysis to detect (pre-)malignant cervical lesions in high-risk HPV-positive women.

Overmeer RM, Louwers JA, Meijer CJ, van Kemenade FJ, Hesselink AT, Daalmeijer NF, Wilting SM, Heideman DA, Verheijen RH, Zaal A, van Baal WM, Berkhof J, Snijders PJ, Steenbergen RD.

Int J Cancer. 2011 Nov 1;129(9):2218-25. doi: 10.1002/ijc.25890. Epub 2011 Mar 11.

8.

Replication factor C recruits DNA polymerase delta to sites of nucleotide excision repair but is not required for PCNA recruitment.

Overmeer RM, Gourdin AM, Giglia-Mari A, Kool H, Houtsmuller AB, Siegal G, Fousteri MI, Mullenders LH, Vermeulen W.

Mol Cell Biol. 2010 Oct;30(20):4828-39. doi: 10.1128/MCB.00285-10. Epub 2010 Aug 16.

9.

hTERT promoter activity and CpG methylation in HPV-induced carcinogenesis.

de Wilde J, Kooter JM, Overmeer RM, Claassen-Kramer D, Meijer CJ, Snijders PJ, Steenbergen RD.

BMC Cancer. 2010 Jun 9;10:271. doi: 10.1186/1471-2407-10-271.

10.

Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells.

Ogi T, Limsirichaikul S, Overmeer RM, Volker M, Takenaka K, Cloney R, Nakazawa Y, Niimi A, Miki Y, Jaspers NG, Mullenders LH, Yamashita S, Fousteri MI, Lehmann AR.

Mol Cell. 2010 Mar 12;37(5):714-27. doi: 10.1016/j.molcel.2010.02.009.

11.

RNF4 and VHL regulate the proteasomal degradation of SUMO-conjugated Hypoxia-Inducible Factor-2alpha.

van Hagen M, Overmeer RM, Abolvardi SS, Vertegaal AC.

Nucleic Acids Res. 2010 Apr;38(6):1922-31. doi: 10.1093/nar/gkp1157. Epub 2009 Dec 21.

12.

Repression of MAL tumour suppressor activity by promoter methylation during cervical carcinogenesis.

Overmeer RM, Henken FE, Bierkens M, Wilting SM, Timmerman I, Meijer CJ, Snijders PJ, Steenbergen RD.

J Pathol. 2009 Nov;219(3):327-36. doi: 10.1002/path.2598.

PMID:
19662663
13.

MAL promoter hypermethylation as a novel prognostic marker in gastric cancer.

Buffart TE, Overmeer RM, Steenbergen RD, Tijssen M, van Grieken NC, Snijders PJ, Grabsch HI, van de Velde CJ, Carvalho B, Meijer GA.

Br J Cancer. 2008 Dec 2;99(11):1802-7. doi: 10.1038/sj.bjc.6604777. Epub 2008 Nov 11.

14.

Association between dense CADM1 promoter methylation and reduced protein expression in high-grade CIN and cervical SCC.

Overmeer RM, Henken FE, Snijders PJ, Claassen-Kramer D, Berkhof J, Helmerhorst TJ, Heideman DA, Wilting SM, Murakami Y, Ito A, Meijer CJ, Steenbergen RD.

J Pathol. 2008 Aug;215(4):388-97. doi: 10.1002/path.2367.

PMID:
18498117
15.

Differential effects of combined Ad5- delta 24RGD and radiation therapy in in vitro versus in vivo models of malignant glioma.

Lamfers ML, Idema S, Bosscher L, Heukelom S, Moeniralm S, van der Meulen-Muileman IH, Overmeer RM, van der Valk P, van Beusechem VW, Gerritsen WR, Vandertop WP, Dirven CM.

Clin Cancer Res. 2007 Dec 15;13(24):7451-8.

16.

Sequential gene promoter methylation during HPV-induced cervical carcinogenesis.

Henken FE, Wilting SM, Overmeer RM, van Rietschoten JG, Nygren AO, Errami A, Schouten JP, Meijer CJ, Snijders PJ, Steenbergen RD.

Br J Cancer. 2007 Nov 19;97(10):1457-64. Epub 2007 Oct 30.

17.

Validity of bioluminescence measurements for noninvasive in vivo imaging of tumor load in small animals.

Klerk CP, Overmeer RM, Niers TM, Versteeg HH, Richel DJ, Buckle T, Van Noorden CJ, van Tellingen O.

Biotechniques. 2007 Jul;43(1 Suppl):7-13, 30. Review.

18.

Chinese hamster cell mutant, V-C8, a model for analysis of Brca2 function.

Wiegant WW, Overmeer RM, Godthelp BC, van Buul PP, Zdzienicka MZ.

Mutat Res. 2006 Aug 30;600(1-2):79-88. Epub 2006 Apr 27.

PMID:
16643964
19.

In-training assessment: qualitative study of effects on supervision and feedback in an undergraduate clinical rotation.

Daelmans HE, Overmeer RM, van der Hem-Stokroos HH, Scherpbier AJ, Stehouwer CD, van der Vleuten CP.

Med Educ. 2006 Jan;40(1):51-8.

PMID:
16441323
20.

Inhibition of angiogenesis and HGF-cMET-elicited malignant processes in human hepatocellular carcinoma cells using adenoviral vector-mediated NK4 gene therapy.

Heideman DA, Overmeer RM, van Beusechem VW, Lamers WH, Hakvoort TB, Snijders PJ, Craanen ME, Offerhaus GJ, Meijer CJ, Gerritsen WR.

Cancer Gene Ther. 2005 Dec;12(12):954-62.

PMID:
15905856
21.

Adenoviral vector-mediated expression of a gene encoding secreted, EpCAM-targeted carboxylesterase-2 sensitises colon cancer spheroids to CPT-11.

Oosterhoff D, Overmeer RM, de Graaf M, van der Meulen IH, Giaccone G, van Beusechem VW, Haisma HJ, Pinedo HM, Gerritsen WR.

Br J Cancer. 2005 Mar 14;92(5):882-7.

22.

Conditionally replicating adenoviruses expressing short hairpin RNAs silence the expression of a target gene in cancer cells.

Carette JE, Overmeer RM, Schagen FH, Alemany R, Barski OA, Gerritsen WR, Van Beusechem VW.

Cancer Res. 2004 Apr 15;64(8):2663-7.

23.

The Arabidopsis AtLIG4 gene is required for the repair of DNA damage, but not for the integration of Agrobacterium T-DNA.

van Attikum H, Bundock P, Overmeer RM, Lee LY, Gelvin SB, Hooykaas PJ.

Nucleic Acids Res. 2003 Jul 15;31(14):4247-55.

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