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Items: 12


p21 maintains senescent cell viability under persistent DNA damage response by restraining JNK and caspase signaling.

Yosef R, Pilpel N, Papismadov N, Gal H, Ovadya Y, Vadai E, Miller S, Porat Z, Ben-Dor S, Krizhanovsky V.

EMBO J. 2017 Aug 1;36(15):2280-2295. doi: 10.15252/embj.201695553. Epub 2017 Jun 12.


Quantitative identification of senescent cells in aging and disease.

Biran A, Zada L, Abou Karam P, Vadai E, Roitman L, Ovadya Y, Porat Z, Krizhanovsky V.

Aging Cell. 2017 Aug;16(4):661-671. doi: 10.1111/acel.12592. Epub 2017 Apr 28.


Senescent cell death brings hopes to life.

Ovadya Y, Krizhanovsky V.

Cell Cycle. 2017 Jan 2;16(1):9-10. doi: 10.1080/15384101.2016.1232088. Epub 2016 Sep 16. No abstract available.


Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL.

Yosef R, Pilpel N, Tokarsky-Amiel R, Biran A, Ovadya Y, Cohen S, Vadai E, Dassa L, Shahar E, Condiotti R, Ben-Porath I, Krizhanovsky V.

Nat Commun. 2016 Apr 6;7:11190. doi: 10.1038/ncomms11190.


A new Twist in kidney fibrosis.

Ovadya Y, Krizhanovsky V.

Nat Med. 2015 Sep;21(9):975-7. doi: 10.1038/nm.3938. No abstract available.


Senescent cells communicate via intercellular protein transfer.

Biran A, Perelmutter M, Gal H, Burton DG, Ovadya Y, Vadai E, Geiger T, Krizhanovsky V.

Genes Dev. 2015 Apr 15;29(8):791-802. doi: 10.1101/gad.259341.115. Epub 2015 Apr 8.


Senescent cells: SASPected drivers of age-related pathologies.

Ovadya Y, Krizhanovsky V.

Biogerontology. 2014 Dec;15(6):627-42. doi: 10.1007/s10522-014-9529-9. Epub 2014 Sep 13. Review.


Cell isolation induces fate changes of bone marrow mesenchymal cells leading to loss or alternatively to acquisition of new differentiation potentials.

Shoshani O, Ravid O, Massalha H, Aharonov A, Ovadya Y, Pevsner-Fischer M, Leshkowitz D, Zipori D.

Stem Cells. 2014 Aug;32(8):2008-20. doi: 10.1002/stem.1719.


Natural killer cell-dependent anti-fibrotic pathway in liver injury via Toll-like receptor-9.

Abu-Tair L, Axelrod JH, Doron S, Ovadya Y, Krizhanovsky V, Galun E, Amer J, Safadi R.

PLoS One. 2013 Dec 10;8(12):e82571. doi: 10.1371/journal.pone.0082571. eCollection 2013.


GSK3β regulates physiological migration of stem/progenitor cells via cytoskeletal rearrangement.

Lapid K, Itkin T, D'Uva G, Ovadya Y, Ludin A, Caglio G, Kalinkovich A, Golan K, Porat Z, Zollo M, Lapidot T.

J Clin Invest. 2013 Apr;123(4):1705-17. doi: 10.1172/JCI64149. Epub 2013 Mar 8. Erratum in: J Clin Invest. 2013 Jul 1;123(7):3183.


FGF-2 expands murine hematopoietic stem and progenitor cells via proliferation of stromal cells, c-Kit activation, and CXCL12 down-regulation.

Itkin T, Ludin A, Gradus B, Gur-Cohen S, Kalinkovich A, Schajnovitz A, Ovadya Y, Kollet O, Canaani J, Shezen E, Coffin DJ, Enikolopov GN, Berg T, Piacibello W, Hornstein E, Lapidot T.

Blood. 2012 Aug 30;120(9):1843-55. doi: 10.1182/blood-2011-11-394692. Epub 2012 May 29.


S1P promotes murine progenitor cell egress and mobilization via S1P1-mediated ROS signaling and SDF-1 release.

Golan K, Vagima Y, Ludin A, Itkin T, Cohen-Gur S, Kalinkovich A, Kollet O, Kim C, Schajnovitz A, Ovadya Y, Lapid K, Shivtiel S, Morris AJ, Ratajczak MZ, Lapidot T.

Blood. 2012 Mar 15;119(11):2478-88. doi: 10.1182/blood-2011-06-358614. Epub 2012 Jan 25.

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