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Items: 1 to 50 of 317

1.

Decline of genetic diversity in ancient domestic stallions in Europe.

Wutke S, Sandoval-Castellanos E, Benecke N, Döhle HJ, Friederich S, Gonzalez J, Hofreiter M, Lõugas L, Magnell O, Malaspinas AS, Morales-Muñiz A, Orlando L, Reissmann M, Trinks A, Ludwig A.

Sci Adv. 2018 Apr 18;4(4):eaap9691. doi: 10.1126/sciadv.aap9691. eCollection 2018 Apr.

PMID:
29675468
2.

Detecting signatures of positive selection along defined branches of a population tree using LSD.

Librado P, Orlando L.

Mol Biol Evol. 2018 Mar 29. doi: 10.1093/molbev/msy053. [Epub ahead of print]

PMID:
29617830
3.

Vibrio tapetis Displays an Original Type IV Secretion System in Strains Pathogenic for Bivalve Molluscs.

Dias GM, Bidault A, Le Chevalier P, Choquet G, Der Sarkissian C, Orlando L, Medigue C, Barbe V, Mangenot S, Thompson CC, Thompson FL, Jacq A, Pichereau V, Paillard C.

Front Microbiol. 2018 Feb 19;9:227. doi: 10.3389/fmicb.2018.00227. eCollection 2018.

4.

Convergent genomic signatures of domestication in sheep and goats.

Alberto FJ, Boyer F, Orozco-terWengel P, Streeter I, Servin B, de Villemereuil P, Benjelloun B, Librado P, Biscarini F, Colli L, Barbato M, Zamani W, Alberti A, Engelen S, Stella A, Joost S, Ajmone-Marsan P, Negrini R, Orlando L, Rezaei HR, Naderi S, Clarke L, Flicek P, Wincker P, Coissac E, Kijas J, Tosser-Klopp G, Chikhi A, Bruford MW, Taberlet P, Pompanon F.

Nat Commun. 2018 Mar 6;9(1):813. doi: 10.1038/s41467-018-03206-y.

5.

Ancient genomes revisit the ancestry of domestic and Przewalski's horses.

Gaunitz C, Fages A, Hanghøj K, Albrechtsen A, Khan N, Schubert M, Seguin-Orlando A, Owens IJ, Felkel S, Bignon-Lau O, de Barros Damgaard P, Mittnik A, Mohaseb AF, Davoudi H, Alquraishi S, Alfarhan AH, Al-Rasheid KAS, Crubézy E, Benecke N, Olsen S, Brown D, Anthony D, Massy K, Pitulko V, Kasparov A, Brem G, Hofreiter M, Mukhtarova G, Baimukhanov N, Lõugas L, Onar V, Stockhammer PW, Krause J, Boldgiv B, Undrakhbold S, Erdenebaatar D, Lepetz S, Mashkour M, Ludwig A, Wallner B, Merz V, Merz I, Zaibert V, Willerslev E, Librado P, Outram AK, Orlando L.

Science. 2018 Apr 6;360(6384):111-114. doi: 10.1126/science.aao3297. Epub 2018 Feb 22.

PMID:
29472442
6.

High-Throughput DNA sequencing of ancient wood.

Wagner S, Lagane F, Seguin-Orlando A, Schubert M, Leroy T, Guichoux E, Chancerel E, Bech-Hebelstrup I, Bernard V, Billard C, Billaud Y, Bolliger M, Croutsch C, Čufar K, Eynaud F, Heussner KU, Köninger J, Langenegger F, Leroy F, Lima C, Martinelli N, Momber G, Billamboz A, Nelle O, Palomo A, Piqué R, Ramstein M, Schweichel R, Stäuble H, Tegel W, Terradas X, Verdin F, Plomion C, Kremer A, Orlando L.

Mol Ecol. 2018 Mar;27(5):1138-1154. doi: 10.1111/mec.14514. Epub 2018 Mar 3.

PMID:
29412519
7.

A southern African origin and cryptic structure in the highly mobile plains zebra.

Pedersen CT, Albrechtsen A, Etter PD, Johnson EA, Orlando L, Chikhi L, Siegismund HR, Heller R.

Nat Ecol Evol. 2018 Mar;2(3):491-498. doi: 10.1038/s41559-017-0453-7. Epub 2018 Jan 22.

PMID:
29358610
8.

Terminal Pleistocene Alaskan genome reveals first founding population of Native Americans.

Moreno-Mayar JV, Potter BA, Vinner L, Steinrücken M, Rasmussen S, Terhorst J, Kamm JA, Albrechtsen A, Malaspinas AS, Sikora M, Reuther JD, Irish JD, Malhi RS, Orlando L, Song YS, Nielsen R, Meltzer DJ, Willerslev E.

Nature. 2018 Jan 11;553(7687):203-207. doi: 10.1038/nature25173. Epub 2018 Jan 3.

PMID:
29323294
9.

A new genus of horse from Pleistocene North America.

Heintzman PD, Zazula GD, MacPhee R, Scott E, Cahill JA, McHorse BK, Kapp JD, Stiller M, Wooller MJ, Orlando L, Southon J, Froese DG, Shapiro B.

Elife. 2017 Nov 28;6. pii: e29944. doi: 10.7554/eLife.29944.

10.

Evaluating the impact of domestication and captivity on the horse gut microbiome.

Metcalf JL, Song SJ, Morton JT, Weiss S, Seguin-Orlando A, Joly F, Feh C, Taberlet P, Coissac E, Amir A, Willerslev E, Knight R, McKenzie V, Orlando L.

Sci Rep. 2017 Nov 14;7(1):15497. doi: 10.1038/s41598-017-15375-9.

11.

Genome-wide Ancestry and Demographic History of African-Descendant Maroon Communities from French Guiana and Suriname.

Fortes-Lima C, Gessain A, Ruiz-Linares A, Bortolini MC, Migot-Nabias F, Bellis G, Moreno-Mayar JV, Restrepo BN, Rojas W, Avendaño-Tamayo E, Bedoya G, Orlando L, Salas A, Helgason A, Gilbert MTP, Sikora M, Schroeder H, Dugoujon JM.

Am J Hum Genet. 2017 Nov 2;101(5):725-736. doi: 10.1016/j.ajhg.2017.09.021.

PMID:
29100086
12.

Survival and divergence in a small group: The extraordinary genomic history of the endangered Apennine brown bear stragglers.

Benazzo A, Trucchi E, Cahill JA, Maisano Delser P, Mona S, Fumagalli M, Bunnefeld L, Cornetti L, Ghirotto S, Girardi M, Ometto L, Panziera A, Rota-Stabelli O, Zanetti E, Karamanlidis A, Groff C, Paule L, Gentile L, Vilà C, Vicario S, Boitani L, Orlando L, Fuselli S, Vernesi C, Shapiro B, Ciucci P, Bertorelle G.

Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9589-E9597. doi: 10.1073/pnas.1707279114. Epub 2017 Oct 24.

13.

The Effects of Captivity on the Mammalian Gut Microbiome.

McKenzie VJ, Song SJ, Delsuc F, Prest TL, Oliverio AM, Korpita TM, Alexiev A, Amato KR, Metcalf JL, Kowalewski M, Avenant NL, Link A, Di Fiore A, Seguin-Orlando A, Feh C, Orlando L, Mendelson JR, Sanders J, Knight R.

Integr Comp Biol. 2017 Oct 1;57(4):690-704. doi: 10.1093/icb/icx090.

PMID:
28985326
14.

Ancient genomes show social and reproductive behavior of early Upper Paleolithic foragers.

Sikora M, Seguin-Orlando A, Sousa VC, Albrechtsen A, Korneliussen T, Ko A, Rasmussen S, Dupanloup I, Nigst PR, Bosch MD, Renaud G, Allentoft ME, Margaryan A, Vasilyev SV, Veselovskaya EV, Borutskaya SB, Deviese T, Comeskey D, Higham T, Manica A, Foley R, Meltzer DJ, Nielsen R, Excoffier L, Mirazon Lahr M, Orlando L, Willerslev E.

Science. 2017 Nov 3;358(6363):659-662. doi: 10.1126/science.aao1807. Epub 2017 Oct 5.

PMID:
28982795
15.

Targeting triple negative breast cancer with histone deacetylase inhibitors.

Fedele P, Orlando L, Cinieri S.

Expert Opin Investig Drugs. 2017 Nov;26(11):1199-1206. doi: 10.1080/13543784.2017.1386172. Epub 2017 Oct 8. Review.

PMID:
28952409
16.

Developing a common framework for evaluating the implementation of genomic medicine interventions in clinical care: the IGNITE Network's Common Measures Working Group.

Orlando LA, Sperber NR, Voils C, Nichols M, Myers RA, Wu RR, Rakhra-Burris T, Levy KD, Levy M, Pollin TI, Guan Y, Horowitz CR, Ramos M, Kimmel SE, McDonough CW, Madden EB, Damschroder LJ.

Genet Med. 2017 Sep 14. doi: 10.1038/gim.2017.144. [Epub ahead of print]

17.

Induced Pluripotent Stem Cells: Advances in the Quest for Genetic Stability during Reprogramming Process.

Turinetto V, Orlando L, Giachino C.

Int J Mol Sci. 2017 Sep 13;18(9). pii: E1952. doi: 10.3390/ijms18091952. Review.

18.

Population characteristics of a large whale shark aggregation inferred from seawater environmental DNA.

Sigsgaard EE, Nielsen IB, Bach SS, Lorenzen ED, Robinson DP, Knudsen SW, Pedersen MW, Jaidah MA, Orlando L, Willerslev E, Møller PR, Thomsen PF.

Nat Ecol Evol. 2016 Nov 21;1(1):4. doi: 10.1038/s41559-016-0004.

PMID:
28812572
19.

Brief Report: Human Acute Myeloid Leukemia Reprogramming to Pluripotency Is a Rare Event and Selects for Patient Hematopoietic Cells Devoid of Leukemic Mutations.

Lee JH, Salci KR, Reid JC, Orlando L, Tanasijevic B, Shapovalova Z, Bhatia M.

Stem Cells. 2017 Sep;35(9):2095-2102. doi: 10.1002/stem.2655. Epub 2017 Jul 31.

PMID:
28758276
20.

Developing a 670k genotyping array to tag ~2M SNPs across 24 horse breeds.

Schaefer RJ, Schubert M, Bailey E, Bannasch DL, Barrey E, Bar-Gal GK, Brem G, Brooks SA, Distl O, Fries R, Finno CJ, Gerber V, Haase B, Jagannathan V, Kalbfleisch T, Leeb T, Lindgren G, Lopes MS, Mach N, da Câmara Machado A, MacLeod JN, McCoy A, Metzger J, Penedo C, Polani S, Rieder S, Tammen I, Tetens J, Thaller G, Verini-Supplizi A, Wade CM, Wallner B, Orlando L, Mickelson JR, McCue ME.

BMC Genomics. 2017 Jul 27;18(1):565. doi: 10.1186/s12864-017-3943-8.

21.

Should endocrine therapy still be used as an initial treatment for postmenopausal women with metastatic breast cancer?

Orlando L, Cinieri S.

Future Oncol. 2017 Jul;13(16):1361-1364. doi: 10.2217/fon-2017-0101. Epub 2017 Jul 7. No abstract available.

22.

The wolf reference genome sequence (Canis lupus lupus) and its implications for Canis spp. population genomics.

Gopalakrishnan S, Samaniego Castruita JA, Sinding MS, Kuderna LFK, Räikkönen J, Petersen B, Sicheritz-Ponten T, Larson G, Orlando L, Marques-Bonet T, Hansen AJ, Dalén L, Gilbert MTP.

BMC Genomics. 2017 Jun 29;18(1):495. doi: 10.1186/s12864-017-3883-3.

23.

Sam68 Allows Selective Targeting of Human Cancer Stem Cells.

Benoit YD, Mitchell RR, Risueño RM, Orlando L, Tanasijevic B, Boyd AL, Aslostovar L, Salci KR, Shapovalova Z, Russell J, Eguchi M, Golubeva D, Graham M, Xenocostas A, Trus MR, Foley R, Leber B, Collins TJ, Bhatia M.

Cell Chem Biol. 2017 Jul 20;24(7):833-844.e9. doi: 10.1016/j.chembiol.2017.05.026. Epub 2017 Jun 22.

PMID:
28648376
24.

Challenges and strategies for implementing genomic services in diverse settings: experiences from the Implementing GeNomics In pracTicE (IGNITE) network.

Sperber NR, Carpenter JS, Cavallari LH, J Damschroder L, Cooper-DeHoff RM, Denny JC, Ginsburg GS, Guan Y, Horowitz CR, Levy KD, Levy MA, Madden EB, Matheny ME, Pollin TI, Pratt VM, Rosenman M, Voils CI, W Weitzel K, Wilke RA, Ryanne Wu R, Orlando LA.

BMC Med Genomics. 2017 May 22;10(1):35. doi: 10.1186/s12920-017-0273-2.

25.

Detecting taxonomic and phylogenetic signals in equid cheek teeth: towards new palaeontological and archaeological proxies.

Cucchi T, Mohaseb A, Peigné S, Debue K, Orlando L, Mashkour M.

R Soc Open Sci. 2017 Apr 5;4(4):160997. doi: 10.1098/rsos.160997. eCollection 2017 Apr.

26.

A Robust Framework for Microbial Archaeology.

Warinner C, Herbig A, Mann A, Fellows Yates JA, Weiß CL, Burbano HA, Orlando L, Krause J.

Annu Rev Genomics Hum Genet. 2017 Aug 31;18:321-356. doi: 10.1146/annurev-genom-091416-035526. Epub 2017 Apr 26. Review.

27.

Ancient genomic changes associated with domestication of the horse.

Librado P, Gamba C, Gaunitz C, Der Sarkissian C, Pruvost M, Albrechtsen A, Fages A, Khan N, Schubert M, Jagannathan V, Serres-Armero A, Kuderna LFK, Povolotskaya IS, Seguin-Orlando A, Lepetz S, Neuditschko M, Thèves C, Alquraishi S, Alfarhan AH, Al-Rasheid K, Rieder S, Samashev Z, Francfort HP, Benecke N, Hofreiter M, Ludwig A, Keyser C, Marques-Bonet T, Ludes B, Crubézy E, Leeb T, Willerslev E, Orlando L.

Science. 2017 Apr 28;356(6336):442-445. doi: 10.1126/science.aam5298.

PMID:
28450643
28.

Less effective selection leads to larger genomes.

Lefébure T, Morvan C, Malard F, François C, Konecny-Dupré L, Guéguen L, Weiss-Gayet M, Seguin-Orlando A, Ermini L, Sarkissian C, Charrier NP, Eme D, Mermillod-Blondin F, Duret L, Vieira C, Orlando L, Douady CJ.

Genome Res. 2017 Jun;27(6):1016-1028. doi: 10.1101/gr.212589.116. Epub 2017 Apr 19.

29.

Making genomic medicine evidence-based and patient-centered: a structured review and landscape analysis of comparative effectiveness research.

Phillips KA, Deverka PA, Sox HC, Khoury MJ, Sandy LG, Ginsburg GS, Tunis SR, Orlando LA, Douglas MP.

Genet Med. 2017 Oct;19(10):1081-1091. doi: 10.1038/gim.2017.21. Epub 2017 Apr 13.

30.

Ancient DNA analysis identifies marine mollusc shells as new metagenomic archives of the past.

Der Sarkissian C, Pichereau V, Dupont C, Ilsøe PC, Perrigault M, Butler P, Chauvaud L, Eiríksson J, Scourse J, Paillard C, Orlando L.

Mol Ecol Resour. 2017 Sep;17(5):835-853. doi: 10.1111/1755-0998.12679. Epub 2017 May 12.

31.

Understanding Preferences for Treatment After Hypothetical First-Time Anterior Shoulder Dislocation: Surveying an Online Panel Utilizing a Novel Shared Decision-Making Tool.

Streufert B, Reed SD, Orlando LA, Taylor DC, Huber JC, Mather RC 3rd.

Orthop J Sports Med. 2017 Mar 20;5(3):2325967117695788. doi: 10.1177/2325967117695788. eCollection 2017 Mar.

32.

Evolutionary Patterns and Processes: Lessons from Ancient DNA.

Leonardi M, Librado P, Der Sarkissian C, Schubert M, Alfarhan AH, Alquraishi SA, Al-Rasheid KA, Gamba C, Willerslev E, Orlando L.

Syst Biol. 2017 Jan 1;66(1):e1-e29. doi: 10.1093/sysbio/syw059. Review. Erratum in: Syst Biol. 2017 Jul 1;66(4):660.

33.

Mitogenomic Phylogeny, Diversification, and Biogeography of South American Spiny Rats.

Fabre PH, Upham NS, Emmons LH, Justy F, Leite YL, Carolina Loss A, Orlando L, Tilak MK, Patterson BD, Douzery EJ.

Mol Biol Evol. 2017 Mar 1;34(3):613-633. doi: 10.1093/molbev/msw261.

PMID:
28025278
34.

Human evolution: a tale from ancient genomes.

Llamas B, Willerslev E, Orlando L.

Philos Trans R Soc Lond B Biol Sci. 2017 Feb 5;372(1713). pii: 20150484. Review.

35.

Spotted phenotypes in horses lost attractiveness in the Middle Ages.

Wutke S, Benecke N, Sandoval-Castellanos E, Döhle HJ, Friederich S, Gonzalez J, Hallsson JH, Hofreiter M, Lõugas L, Magnell O, Morales-Muniz A, Orlando L, Pálsdóttir AH, Reissmann M, Ruttkay M, Trinks A, Ludwig A.

Sci Rep. 2016 Dec 7;6:38548. doi: 10.1038/srep38548.

36.

Taming the Past: Ancient DNA and the Study of Animal Domestication.

MacHugh DE, Larson G, Orlando L.

Annu Rev Anim Biosci. 2017 Feb 8;5:329-351. doi: 10.1146/annurev-animal-022516-022747. Epub 2016 Oct 28. Review.

PMID:
27813680
37.

gargammel: a sequence simulator for ancient DNA.

Renaud G, Hanghøj K, Willerslev E, Orlando L.

Bioinformatics. 2017 Feb 15;33(4):577-579. doi: 10.1093/bioinformatics/btw670.

38.

Combining bleach and mild predigestion improves ancient DNA recovery from bones.

Boessenkool S, Hanghøj K, Nistelberger HM, Der Sarkissian C, Gondek AT, Orlando L, Barrett JH, Star B.

Mol Ecol Resour. 2017 Jul;17(4):742-751. doi: 10.1111/1755-0998.12623. Epub 2016 Dec 15.

PMID:
27790833
39.

Response of extensive breast cancer skin metastases to rechallenge with trastuzumab together with low-dose chemotherapy and insulin.

Orlando L, Schiavone P, Calvani N, Fedele P, Goldhirsch A, Cinieri S.

Tumori. 2016 Nov 11;102(Suppl. 2). doi: 10.5301/tj.5000488.

PMID:
27002949
40.

Early cave art and ancient DNA record the origin of European bison.

Soubrier J, Gower G, Chen K, Richards SM, Llamas B, Mitchell KJ, Ho SY, Kosintsev P, Lee MS, Baryshnikov G, Bollongino R, Bover P, Burger J, Chivall D, Crégut-Bonnoure E, Decker JE, Doronichev VB, Douka K, Fordham DA, Fontana F, Fritz C, Glimmerveen J, Golovanova LV, Groves C, Guerreschi A, Haak W, Higham T, Hofman-Kamińska E, Immel A, Julien MA, Krause J, Krotova O, Langbein F, Larson G, Rohrlach A, Scheu A, Schnabel RD, Taylor JF, Tokarska M, Tosello G, van der Plicht J, van Loenen A, Vigne JD, Wooley O, Orlando L, Kowalczyk R, Shapiro B, Cooper A.

Nat Commun. 2016 Oct 18;7:13158. doi: 10.1038/ncomms13158.

41.

Discordance in pathology report after central pathology review: Implications for breast cancer adjuvant treatment.

Orlando L, Viale G, Bria E, Lutrino ES, Sperduti I, Carbognin L, Schiavone P, Quaranta A, Fedele P, Caliolo C, Calvani N, Criscuolo M, Cinieri S.

Breast. 2016 Dec;30:151-155. doi: 10.1016/j.breast.2016.09.015. Epub 2016 Oct 14.

PMID:
27750105
42.

The Evolutionary Origin and Genetic Makeup of Domestic Horses.

Librado P, Fages A, Gaunitz C, Leonardi M, Wagner S, Khan N, Hanghøj K, Alquraishi SA, Alfarhan AH, Al-Rasheid KA, Der Sarkissian C, Schubert M, Orlando L.

Genetics. 2016 Oct;204(2):423-434. Review.

43.

Fast, Accurate and Automatic Ancient Nucleosome and Methylation Maps with epiPALEOMIX.

Hanghøj K, Seguin-Orlando A, Schubert M, Madsen T, Pedersen JS, Willerslev E, Orlando L.

Mol Biol Evol. 2016 Dec;33(12):3284-3298. Epub 2016 Sep 13.

44.

Veno-occlusive disease nurse management: development of a dynamic monitoring tool by the GITMO nursing group.

Botti S, Orlando L, Gargiulo G, Cecco VD, Banfi M, Duranti L, Samarani E, Netti MG, Deiana M, Galuppini V, Pignatelli AC, Ceresoli R, Vedovetto A, Rostagno E, Bambaci M, Dellaversana C, Luminari S, Bonifazi F.

Ecancermedicalscience. 2016 Aug 8;10:661. doi: 10.3332/ecancer.2016.661. eCollection 2016.

45.

Risk management of onco-hematological drugs: how and how fast can we improve?

Altini M, Bernabini M, Marchetti P, Orlando L, Rebesco B, Sirna V.

Tumori. 2016 Aug 29;102(Suppl. 1):15-29. doi: 10.5301/tj.5000540. [Epub ahead of print]

PMID:
27581596
46.

Experimental conditions improving in-solution target enrichment for ancient DNA.

Cruz-Dávalos DI, Llamas B, Gaunitz C, Fages A, Gamba C, Soubrier J, Librado P, Seguin-Orlando A, Pruvost M, Alfarhan AH, Alquraishi SA, Al-Rasheid KAS, Scheu A, Beneke N, Ludwig A, Cooper A, Willerslev E, Orlando L.

Mol Ecol Resour. 2017 May;17(3):508-522. doi: 10.1111/1755-0998.12595. Epub 2016 Sep 18.

PMID:
27566552
47.

Postglacial viability and colonization in North America's ice-free corridor.

Pedersen MW, Ruter A, Schweger C, Friebe H, Staff RA, Kjeldsen KK, Mendoza ML, Beaudoin AB, Zutter C, Larsen NK, Potter BA, Nielsen R, Rainville RA, Orlando L, Meltzer DJ, Kjær KH, Willerslev E.

Nature. 2016 Sep 1;537(7618):45-49. doi: 10.1038/nature19085. Epub 2016 Aug 10.

PMID:
27509852
48.

The origin of ambling horses.

Wutke S, Andersson L, Benecke N, Sandoval-Castellanos E, Gonzalez J, Hallsson JH, Lõugas L, Magnell O, Morales-Muniz A, Orlando L, Pálsdóttir AH, Reissmann M, Muñoz-Rodríguez MB, Ruttkay M, Trinks A, Hofreiter M, Ludwig A.

Curr Biol. 2016 Aug 8;26(15):R697-R699. doi: 10.1016/j.cub.2016.07.001.

49.

Synergistic roles of climate warming and human occupation in Patagonian megafaunal extinctions during the Last Deglaciation.

Metcalf JL, Turney C, Barnett R, Martin F, Bray SC, Vilstrup JT, Orlando L, Salas-Gismondi R, Loponte D, Medina M, De Nigris M, Civalero T, Fernández PM, Gasco A, Duran V, Seymour KL, Otaola C, Gil A, Paunero R, Prevosti FJ, Bradshaw CJ, Wheeler JC, Borrero L, Austin JJ, Cooper A.

Sci Adv. 2016 Jun 17;2(6):e1501682. doi: 10.1126/sciadv.1501682. eCollection 2016 Jun.

50.

Impact of Genetic Testing and Family Health History Based Risk Counseling on Behavior Change and Cognitive Precursors for Type 2 Diabetes.

Wu RR, Myers RA, Hauser ER, Vorderstrasse A, Cho A, Ginsburg GS, Orlando LA.

J Genet Couns. 2017 Feb;26(1):133-140. doi: 10.1007/s10897-016-9988-z. Epub 2016 Jun 14.

PMID:
27296809

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