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Items: 6


Combined treatment of adenosine nucleoside inhibitor NITD008 and histone deacetylase inhibitor vorinostat represents an immunotherapy strategy to ameliorate West Nile virus infection.

Nelson J, Roe K, Orillo B, Shi PY, Verma S.

Antiviral Res. 2015 Oct;122:39-45. doi: 10.1016/j.antiviral.2015.07.008. Epub 2015 Jul 29.


Reduced immune cell infiltration and increased pro-inflammatory mediators in the brain of Type 2 diabetic mouse model infected with West Nile virus.

Kumar M, Roe K, Nerurkar PV, Orillo B, Thompson KS, Verma S, Nerurkar VR.

J Neuroinflammation. 2014 Apr 21;11:80. doi: 10.1186/1742-2094-11-80.


Inflammasome adaptor protein Apoptosis-associated speck-like protein containing CARD (ASC) is critical for the immune response and survival in west Nile virus encephalitis.

Kumar M, Roe K, Orillo B, Muruve DA, Nerurkar VR, Gale M Jr, Verma S.

J Virol. 2013 Apr;87(7):3655-67. doi: 10.1128/JVI.02667-12. Epub 2013 Jan 9.


Impaired virus clearance, compromised immune response and increased mortality in type 2 diabetic mice infected with West Nile virus.

Kumar M, Roe K, Nerurkar PV, Namekar M, Orillo B, Verma S, Nerurkar VR.

PLoS One. 2012;7(8):e44682. doi: 10.1371/journal.pone.0044682. Epub 2012 Aug 31.


West Nile virus-induced disruption of the blood-brain barrier in mice is characterized by the degradation of the junctional complex proteins and increase in multiple matrix metalloproteinases.

Roe K, Kumar M, Lum S, Orillo B, Nerurkar VR, Verma S.

J Gen Virol. 2012 Jun;93(Pt 6):1193-203. doi: 10.1099/vir.0.040899-0. Epub 2012 Mar 7.

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