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Items: 39

1.

Inhibition of telomerase induces alternative lengthening of telomeres during human esophageal carcinogenesis.

Queisser A, Heeg S, Thaler M, von Werder A, Opitz OG.

Cancer Genet. 2013 Nov;206(11):374-86. doi: 10.1016/j.cancergen.2013.10.001. Epub 2013 Oct 11.

PMID:
24331919
2.

The many faces of chondrosarcoma of bone, own cases and review of the literature with an emphasis on radiology, pathology and treatment.

Herget GW, Uhl M, Opitz OG, Adler CP, Südkamp NP, Knöller S.

Acta Chir Orthop Traumatol Cech. 2011;78(6):501-9. Review.

PMID:
22217402
3.

Impact of preoperative targeted therapy on postoperative complications after resection of colorectal liver metastases.

Neeff HP, Drognitz O, Klock A, Illerhaus G, Opitz OG, Hopt UT, Makowiec F.

Int J Colorectal Dis. 2012 May;27(5):635-45. doi: 10.1007/s00384-011-1360-z. Epub 2011 Dec 6.

PMID:
22139030
4.

Occurrence of multipolar mitoses and association with Aurora-A/-B kinases and p53 mutations in aneuploid esophageal carcinoma cells.

Fichter CD, Herz C, Münch C, Opitz OG, Werner M, Lassmann S.

BMC Cell Biol. 2011 Apr 6;12:13. doi: 10.1186/1471-2121-12-13.

5.

EGFR overexpression induces activation of telomerase via PI3K/AKT-mediated phosphorylation and transcriptional regulation through Hif1-alpha in a cellular model of oral-esophageal carcinogenesis.

Heeg S, Hirt N, Queisser A, Schmieg H, Thaler M, Kunert H, Quante M, Goessel G, von Werder A, Harder J, Beijersbergen R, Blum HE, Nakagawa H, Opitz OG.

Cancer Sci. 2011 Feb;102(2):351-60. doi: 10.1111/j.1349-7006.2010.01796.x. Epub 2010 Dec 12.

6.

Chemotherapy, liver injury, and postoperative complications in colorectal liver metastases.

Makowiec F, Möhrle S, Neeff H, Drognitz O, Illerhaus G, Opitz OG, Hopt UT, zur Hausen A.

J Gastrointest Surg. 2011 Jan;15(1):153-64. doi: 10.1007/s11605-010-1368-7.

PMID:
21061183
7.

EGFR and HER2 expression in advanced biliary tract cancer.

Harder J, Waiz O, Otto F, Geissler M, Olschewski M, Weinhold B, Blum HE, Schmitt-Graeff A, Opitz OG.

World J Gastroenterol. 2009 Sep 28;15(36):4511-7.

8.

Potential germline epimutations in Lynch syndrome: more evidence for genetics superseding epigenetics in inactivation of DNA mismatch repair genes in hereditary colorectal cancer.

Ebert MP, Opitz OG.

Gastroenterology. 2009 Oct;137(4):1524-7. doi: 10.1053/j.gastro.2009.08.020. Epub 2009 Aug 28. No abstract available.

PMID:
19717130
9.

Telomere dysfunction and DNA damage checkpoints in diseases and cancer of the gastrointestinal tract.

Rudolph KL, Hartmann D, Opitz OG.

Gastroenterology. 2009 Sep;137(3):754-62. doi: 10.1053/j.gastro.2009.07.037. Epub 2009 Jul 18. Review. No abstract available.

PMID:
19619548
10.

The miR-200 family: central player for gain and loss of the epithelial phenotype.

Spaderna S, Brabletz T, Opitz OG.

Gastroenterology. 2009 May;136(5):1835-7. doi: 10.1053/j.gastro.2009.03.009. Epub 2009 Mar 25. No abstract available.

PMID:
19324106
11.

CpG-island methylation of the ER promoter in colorectal cancer: analysis of micrometastases in lymph nodes from UICC stage I and II patients.

Harder J, Engelstaedter V, Usadel H, Lassmann S, Werner M, Baier P, Otto F, Varbanova M, Schaeffner E, Olschewski M, Blum HE, Opitz OG.

Br J Cancer. 2009 Jan 27;100(2):360-5. doi: 10.1038/sj.bjc.6604859. Epub 2009 Jan 13.

12.

The new look of colorectal cancer stem cells.

Lassmann S, Opitz OG.

Gastroenterology. 2008 Apr;134(4):1262-4. doi: 10.1053/j.gastro.2008.02.050. No abstract available.

PMID:
18395109
13.

Quantitative promoter methylation analysis of hepatocellular carcinoma, cirrhotic and normal liver.

Harder J, Opitz OG, Brabender J, Olschewski M, Blum HE, Nomoto S, Usadel H.

Int J Cancer. 2008 Jun 15;122(12):2800-4. doi: 10.1002/ijc.23433.

14.

Chronic colitis due to an epithelial barrier defect: the role of kindlin-1 isoforms.

Kern JS, Herz C, Haan E, Moore D, Nottelmann S, von Lilien T, Greiner P, Schmitt-Graeff A, Opitz OG, Bruckner-Tuderman L, Has C.

J Pathol. 2007 Dec;213(4):462-70.

PMID:
17955455
15.

Inducing cellular senescence using defined genetic elements.

Nakagawa H, Opitz OG.

Methods Mol Biol. 2007;371:167-78. Review.

PMID:
17634581
16.

Interleukin-10 and viral clearance: translation to viral hepatitis.

Thimme R, Opitz OG.

Gastroenterology. 2007 Jun;132(7):2611-3. No abstract available.

PMID:
17570238
17.

[Gastric cancer--risk factors and medical therapy].

Harder J, Opitz OG.

Praxis (Bern 1994). 2006 Jun 21;95(25-26):1021-8. Review. German.

PMID:
16836062
18.

In vitro transformation models: modeling human cancer.

Heeg S, Doebele M, von Werder A, Opitz OG.

Cell Cycle. 2006 Mar;5(6):630-4. Epub 2006 Mar 15. Review.

PMID:
16582608
19.

Telomere dysfunction and loss of p53 cooperate in defective mitotic segregation of chromosomes in cancer cells.

Pantic M, Zimmermann S, El Daly H, Opitz OG, Popp S, Boukamp P, Martens UM.

Oncogene. 2006 Jul 27;25(32):4413-20. Epub 2006 Mar 20.

PMID:
16547498
20.

Effect of vardenafil, an inhibitor of phosphodiesterase-5, on portal haemodynamics in normal and cirrhotic liver -- results of a pilot study.

Deibert P, Schumacher YO, Ruecker G, Opitz OG, Blum HE, Rössle M, Kreisel W.

Aliment Pharmacol Ther. 2006 Jan 1;23(1):121-8.

21.

Creating oral squamous cancer cells: a cellular model of oral-esophageal carcinogenesis.

Goessel G, Quante M, Hahn WC, Harada H, Heeg S, Suliman Y, Doebele M, von Werder A, Fulda C, Nakagawa H, Rustgi AK, Blum HE, Opitz OG.

Proc Natl Acad Sci U S A. 2005 Oct 25;102(43):15599-604. Epub 2005 Oct 20.

22.

Telomeres, telomerase and malignant transformation.

Opitz OG.

Curr Mol Med. 2005 Mar;5(2):219-26. Review.

PMID:
15974876
23.

Differential transcriptional regulation of human telomerase in a cellular model representing important genetic alterations in esophageal squamous carcinogenesis.

Quante M, Heeg S, von Werder A, Goessel G, Fulda C, Doebele M, Nakagawa H, Beijersbergen R, Blum HE, Opitz OG.

Carcinogenesis. 2005 Nov;26(11):1879-89. Epub 2005 Jun 15.

PMID:
15958520
24.

A mouse model of oral-esophageal carcinogenesis.

Opitz OG, Quante M, von Werder A, Heeg S, Blum HE.

Onkologie. 2005 Jan;28(1):44-8.

PMID:
15696643
25.

[Cholestatic liver diseases].

Thimme R, Opitz OG, Blum HE, Kreisel W.

Ther Umsch. 2004 Aug;61(8):521-7. Review. German.

PMID:
15457969
26.

Ha-Ras(G12V) induces senescence in primary and immortalized human esophageal keratinocytes with p53 dysfunction.

Takaoka M, Harada H, Deramaudt TB, Oyama K, Andl CD, Johnstone CN, Rhoades B, Enders GH, Opitz OG, Nakagawa H.

Oncogene. 2004 Sep 2;23(40):6760-8.

PMID:
15273725
27.

Telomerase induces immortalization of human esophageal keratinocytes without p16INK4a inactivation.

Harada H, Nakagawa H, Oyama K, Takaoka M, Andl CD, Jacobmeier B, von Werder A, Enders GH, Opitz OG, Rustgi AK.

Mol Cancer Res. 2003 Aug;1(10):729-38.

28.

A mouse model of human oral-esophageal cancer.

Opitz OG, Harada H, Suliman Y, Rhoades B, Sharpless NE, Kent R, Kopelovich L, Nakagawa H, Rustgi AK.

J Clin Invest. 2002 Sep;110(6):761-9.

29.

[Cholestatic liver diseases: diagnosis and therapy of primary sclerosing cholangitis].

Opitz OG, Thimme R, Kreisel W.

Dtsch Med Wochenschr. 2002 Sep 6;127(36):1827-30. Review. German. No abstract available.

PMID:
12215927
30.

[Cholestatic liver diseases: diagnosis and therapy of primary biliary cirrhosis].

Thimme R, Opitz OG, Kreisel W.

Dtsch Med Wochenschr. 2002 Sep 6;127(36):1823-6. Review. German. No abstract available.

PMID:
12215926
31.

Cell cycle dysregulation in oral cancer.

Todd R, Hinds PW, Munger K, Rustgi AK, Opitz OG, Suliman Y, Wong DT.

Crit Rev Oral Biol Med. 2002;13(1):51-61. Review.

PMID:
12097237
32.

Cyclin D1 overexpression and p53 inactivation immortalize primary oral keratinocytes by a telomerase-independent mechanism.

Opitz OG, Suliman Y, Hahn WC, Harada H, Blum HE, Rustgi AK.

J Clin Invest. 2001 Sep;108(5):725-32.

33.

p63 expression is associated with p53 loss in oral-esophageal epithelia of p53-deficient mice.

Suliman Y, Opitz OG, Avadhani A, Burns TC, El-Deiry W, Wong DT, Rustgi AK.

Cancer Res. 2001 Sep 1;61(17):6467-73.

35.

The Krüppel-like transcriptional factors Zf9 and GKLF coactivate the human keratin 4 promoter and physically interact.

Okano J, Opitz OG, Nakagawa H, Jenkins TD, Friedman SL, Rustgi AK.

FEBS Lett. 2000 May 4;473(1):95-100.

36.

Dual function of the epithelial specific ets transcription factor, ELF3, in modulating differentiation.

Brembeck FH, Opitz OG, Libermann TA, Rustgi AK.

Oncogene. 2000 Apr 6;19(15):1941-9.

37.

Cellular characterization and successful transfection of serially subcultured normal human esophageal keratinocytes.

Compton CC, Warland G, Nakagawa H, Opitz OG, Rustgi AK.

J Cell Physiol. 1998 Nov;177(2):274-81.

PMID:
9766524
38.
39.

Transactivation of the human keratin 4 and Epstein-Barr virus ED-L2 promoters by gut-enriched Krüppel-like factor.

Jenkins TD, Opitz OG, Okano J, Rustgi AK.

J Biol Chem. 1998 Apr 24;273(17):10747-54.

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