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Items: 14


Targeting TAO Kinases Using a New Inhibitor Compound Delays Mitosis and Induces Mitotic Cell Death in Centrosome Amplified Breast Cancer Cells.

Koo CY, Giacomini C, Reyes-Corral M, Olmos Y, Tavares IA, Marson CM, Linardopoulos S, Tutt AN, Morris JDH.

Mol Cancer Ther. 2017 Nov;16(11):2410-2421. doi: 10.1158/1535-7163.MCT-17-0077. Epub 2017 Aug 22.


Membrane Binding by CHMP7 Coordinates ESCRT-III-Dependent Nuclear Envelope Reformation.

Olmos Y, Perdrix-Rosell A, Carlton JG.

Curr Biol. 2016 Oct 10;26(19):2635-2641. doi: 10.1016/j.cub.2016.07.039. Epub 2016 Sep 8.


Regulation of endothelial dynamics by PGC-1α relies on ROS control of VEGF-A signaling.

García-Quintans N, Prieto I, Sánchez-Ramos C, Luque A, Arza E, Olmos Y, Monsalve M.

Free Radic Biol Med. 2016 Apr;93:41-51. doi: 10.1016/j.freeradbiomed.2016.01.021. Epub 2016 Jan 29.


The ESCRT machinery: new roles at new holes.

Olmos Y, Carlton JG.

Curr Opin Cell Biol. 2016 Feb;38:1-11. doi: 10.1016/ Epub 2016 Jan 15. Review.


ESCRT-III controls nuclear envelope reformation.

Olmos Y, Hodgson L, Mantell J, Verkade P, Carlton JG.

Nature. 2015 Jun 11;522(7555):236-9. doi: 10.1038/nature14503. Epub 2015 Jun 3.


SIRT6 modulates paclitaxel and epirubicin resistance and survival in breast cancer.

Khongkow M, Olmos Y, Gong C, Gomes AR, Monteiro LJ, Yagüe E, Cavaco TB, Khongkow P, Man EP, Laohasinnarong S, Koo CY, Harada-Shoji N, Tsang JW, Coombes RC, Schwer B, Khoo US, Lam EW.

Carcinogenesis. 2013 Jul;34(7):1476-86. doi: 10.1093/carcin/bgt098. Epub 2013 Mar 20.


SirT1 regulation of antioxidant genes is dependent on the formation of a FoxO3a/PGC-1α complex.

Olmos Y, Sánchez-Gómez FJ, Wild B, García-Quintans N, Cabezudo S, Lamas S, Monsalve M.

Antioxid Redox Signal. 2013 Nov 1;19(13):1507-21. doi: 10.1089/ars.2012.4713. Epub 2013 Apr 15.


Peroxisome proliferator-activated receptors-α and -γ, and cAMP-mediated pathways, control retinol-binding protein-4 gene expression in brown adipose tissue.

Rosell M, Hondares E, Iwamoto S, Gonzalez FJ, Wabitsch M, Staels B, Olmos Y, Monsalve M, Giralt M, Iglesias R, Villarroya F.

Endocrinology. 2012 Mar;153(3):1162-73. doi: 10.1210/en.2011-1367. Epub 2012 Jan 17.


Peroxisome proliferator-activated receptor α (PPARα) induces PPARγ coactivator 1α (PGC-1α) gene expression and contributes to thermogenic activation of brown fat: involvement of PRDM16.

Hondares E, Rosell M, Díaz-Delfín J, Olmos Y, Monsalve M, Iglesias R, Villarroya F, Giralt M.

J Biol Chem. 2011 Dec 16;286(50):43112-22. doi: 10.1074/jbc.M111.252775. Epub 2011 Oct 27.


ERβ1 represses FOXM1 expression through targeting ERα to control cell proliferation in breast cancer.

Horimoto Y, Hartman J, Millour J, Pollock S, Olmos Y, Ho KK, Coombes RC, Poutanen M, Mäkelä SI, El-Bahrawy M, Speirs V, Lam EW.

Am J Pathol. 2011 Sep;179(3):1148-56. doi: 10.1016/j.ajpath.2011.05.052. Epub 2011 Jul 16.


The complex biology of FOXO.

Monsalve M, Olmos Y.

Curr Drug Targets. 2011 Aug;12(9):1322-50. Review.


Interplay between SIRT proteins and tumour suppressor transcription factors in chemotherapeutic resistance of cancer.

Olmos Y, Brosens JJ, Lam EW.

Drug Resist Updat. 2011 Feb;14(1):35-44. doi: 10.1016/j.drup.2010.12.001. Epub 2010 Dec 30. Review.


Inactivation of Foxo3a and subsequent downregulation of PGC-1 alpha mediate nitric oxide-induced endothelial cell migration.

Borniquel S, García-Quintáns N, Valle I, Olmos Y, Wild B, Martínez-Granero F, Soria E, Lamas S, Monsalve M.

Mol Cell Biol. 2010 Aug;30(16):4035-44. doi: 10.1128/MCB.00175-10. Epub 2010 Jun 14.


Mutual dependence of Foxo3a and PGC-1alpha in the induction of oxidative stress genes.

Olmos Y, Valle I, Borniquel S, Tierrez A, Soria E, Lamas S, Monsalve M.

J Biol Chem. 2009 May 22;284(21):14476-84. doi: 10.1074/jbc.M807397200. Epub 2009 Mar 26.

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