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Items: 1 to 50 of 910

1.

[Twenty-Five Cases of Locally Advanced Rectal Cancer That Underwent Laparoscopic Surgery after Preoperative Chemotherapy].

Okuda H, Nakahara M, Yano T, Bekki T, Takechi H, Yoshikawa T, Mochizuki T, Abe T, Fujikuni N, Sasada T, Yamaki M, Amano H, Noriyuki T.

Gan To Kagaku Ryoho. 2017 Nov;44(12):1772-1774. Japanese.

PMID:
29394771
2.

CCR2 upregulation in DRG neurons plays a crucial role in gastric hyperalgesia associated with diabetic gastropathy.

Aye-Mon A, Hori K, Kozakai Y, Nakagawa T, Hiraga S, Nakamura T, Shiraishi Y, Okuda H, Ozaki N.

Mol Pain. 2018 Jan-Dec;14:1744806917751322. doi: 10.1177/1744806917751322.

3.

First-line chemotherapy with S-1 alone or S-1 plus cisplatin for elderly patients with advanced gastric cancer: a multicenter propensity score matched study.

Makiyama A, Kunieda K, Noguchi M, Kajiwara T, Tamura T, Takeda K, Sugiyama J, Minashi K, Moriwaki T, Sugimoto N, Nagase M, Negoro Y, Tsuda T, Shimodaira H, Okano N, Tsuji A, Sakai D, Yanagihara K, Ueda S, Tamura S, Otsu S, Honda T, Matsushita Y, Okuno T, Kashiwada T, Nozaki A, Ebi M, Okuda H, Shimokawa M, Hironaka S, Hyodo I, Baba E, Boku N, Muro K, Esaki T.

Gastric Cancer. 2018 Jan 20. doi: 10.1007/s10120-018-0797-y. [Epub ahead of print]

PMID:
29353332
4.

β-cell-specific overexpression of adiponectin receptor 1 does not improve diabetes mellitus in Akita mice.

Choi J, Kobayashi H, Okuda H, Harada KH, Takeda M, Fujimoto H, Yamane S, Tanaka D, Youssefian S, Inagaki N, Koizumi A.

PLoS One. 2018 Jan 5;13(1):e0190863. doi: 10.1371/journal.pone.0190863. eCollection 2018.

5.

Recent Progress of Bypass Surgery to the Dialysis-Dependent Patients with Critical Limb Ischemia.

Azuma N, Kikuchi S, Okuda H, Miyake K, Koya A.

Ann Vasc Dis. 2017 Sep 25;10(3). pii: ra.17-00076. doi: 10.3400/avd.ra.17-00076.

6.

Katanin-like 2 (KATNAL2) functions in multiple aspects of haploid male germ cell development in the mouse.

Dunleavy JEM, Okuda H, O'Connor AE, Merriner DJ, O'Donnell L, Jamsai D, Bergmann M, O'Bryan MK.

PLoS Genet. 2017 Nov 14;13(11):e1007078. doi: 10.1371/journal.pgen.1007078. eCollection 2017 Nov.

7.

Skin Necrosis Due to the Extravasation of Irritant Anticancer Agents.

Okuda H, Masatsugu A, Takako S, Arai R.

Intern Med. 2017 Nov 1. doi: 10.2169/internalmedicine.9329-17. [Epub ahead of print]

8.

A review of functional heterogeneity among astrocytes and the CS56-specific antibody-mediated detection of a subpopulation of astrocytes in adult brains.

Okuda H.

Anat Sci Int. 2018 Mar;93(2):161-168. doi: 10.1007/s12565-017-0420-z. Epub 2017 Oct 31. Review.

PMID:
29086253
9.

Activation of TGF-β signaling induces cell death via the unfolded protein response in Fuchs endothelial corneal dystrophy.

Okumura N, Hashimoto K, Kitahara M, Okuda H, Ueda E, Watanabe K, Nakahara M, Sato T, Kinoshita S, Tourtas T, Schlötzer-Schrehardt U, Kruse F, Koizumi N.

Sci Rep. 2017 Jul 28;7(1):6801. doi: 10.1038/s41598-017-06924-3.

10.

Complete torsion of gallbladder following laparoscopic cholecystectomy: A case study.

Bekki T, Abe T, Amano H, Fujikuni N, Okuda H, Sasada T, Yamaki M, Kobayashi T, Noriyuki T, Nakahara M.

Int J Surg Case Rep. 2017;37:257-260. doi: 10.1016/j.ijscr.2017.06.051. Epub 2017 Jun 29.

11.

Sustained Activation of the Unfolded Protein Response Induces Cell Death in Fuchs' Endothelial Corneal Dystrophy.

Okumura N, Kitahara M, Okuda H, Hashimoto K, Ueda E, Nakahara M, Kinoshita S, Young RD, Quantock AJ, Tourtas T, Schlötzer-Schrehardt U, Kruse F, Koizumi N.

Invest Ophthalmol Vis Sci. 2017 Jul 1;58(9):3697-3707. doi: 10.1167/iovs.16-21023.

PMID:
28727885
12.

Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, isopropyl acetate and propyleneimine, and classifications on carcinogenicity, occupational sensitizer and reproductive toxicant.

Committee for Recommendation of Occupational Exposure Limits, Japan Society for Occupational Health, Azuma K, Endo G, Endo Y, Fukushima T, Hara K, Hori H, Horie S, Horiguchi H, Ichiba M, Ichihara G, Ikeda M, Ishitake T, Ito A, Ito Y, Iwasawa S, Kamijima M, Karita K, Katoh T, Kawai T, Kawamoto T, Kishi R, Kumagai S, Kusaka Y, Matsumoto A, Miyagawa M, Miyauchi H, Morimoto Y, Nagano K, Naito H, Nakajima T, Nomiyama T, Okuda H, Omae K, Sakurai H, Sato K, Sobue T, Suwazono Y, Takebayashi T, Takeshita T, Takeuchi A, Takeuchi A, Tanaka M, Tanaka S, Tsukahara T, Tsunoda M, Ueno S, Ueyama J, Umeda Y, Yamano Y, Yamauchi T, Yano E.

J Occup Health. 2017 Jul 27;59(4):364-366. doi: 10.1539/joh.17-0148-OP. Epub 2017 Jun 26. No abstract available.

13.

Five-weekly S-1 plus cisplatin therapy combined with trastuzumab therapy in HER2-positive gastric cancer: a phase II trial and biomarker study (WJOG7212G).

Miura Y, Sukawa Y, Hironaka S, Mori M, Nishikawa K, Tokunaga S, Okuda H, Sakamoto T, Taku K, Nishikawa K, Moriwaki T, Negoro Y, Kimura Y, Uchino K, Shinozaki K, Shinozaki H, Musha N, Yoshiyama H, Tsuda T, Miyata Y, Sugimoto N, Shirakawa T, Ito M, Yonesaka K, Yoshimura K, Boku N, Nosho K, Takano T, Hyodo I.

Gastric Cancer. 2018 Jan;21(1):84-95. doi: 10.1007/s10120-017-0725-6. Epub 2017 May 11.

PMID:
28497176
14.

18F-Labeled Pyrido[3,4-d]pyrimidine as an Effective Probe for Imaging of L858R Mutant Epidermal Growth Factor Receptor.

Kimura H, Okuda H, Ishiguro M, Arimitsu K, Makino A, Nishii R, Miyazaki A, Yagi Y, Watanabe H, Kawasaki I, Ono M, Saji H.

ACS Med Chem Lett. 2017 Mar 20;8(4):418-422. doi: 10.1021/acsmedchemlett.6b00520. eCollection 2017 Apr 13.

PMID:
28435529
15.

Cooperative gene activation by AF4 and DOT1L drives MLL-rearranged leukemia.

Okuda H, Stanojevic B, Kanai A, Kawamura T, Takahashi S, Matsui H, Takaori-Kondo A, Yokoyama A.

J Clin Invest. 2017 May 1;127(5):1918-1931. doi: 10.1172/JCI91406. Epub 2017 Apr 10.

16.

Evaluating the Properties of Poly(lactic-co-glycolic acid) Nanoparticle Formulations Encapsulating a Hydrophobic Drug by Using the Quality by Design Approach.

Kozaki M, Kobayashi SI, Goda Y, Okuda H, Sakai-Kato K.

Chem Pharm Bull (Tokyo). 2017;65(3):218-228. doi: 10.1248/cpb.c16-00415.

17.

EZH2 expression is a prognostic biomarker in patients with colorectal cancer treated with anti-EGFR therapeutics.

Yamamoto I, Nosho K, Kanno S, Igarashi H, Kurihara H, Ishigami K, Ishiguro K, Mitsuhashi K, Maruyama R, Koide H, Okuda H, Hasegawa T, Sukawa Y, Okita K, Takemasa I, Yamamoto H, Shinomura Y, Nakase H.

Oncotarget. 2017 Mar 14;8(11):17810-17818. doi: 10.18632/oncotarget.14863.

18.

Systematic characterization of human testis-specific actin capping protein β3 as a possible biomarker for male infertility.

Soda T, Miyagawa Y, Ueda N, Takezawa K, Okuda H, Fukuhara S, Fujita K, Kiuchi H, Uemura M, Okamoto Y, Tsujimura A, Tanaka H, Nonomura N.

Hum Reprod. 2017 Mar 1;32(3):514-522. doi: 10.1093/humrep/dew353.

PMID:
28104696
19.

A review of reproductive and developmental toxicity of silver nanoparticles in laboratory animals.

Ema M, Okuda H, Gamo M, Honda K.

Reprod Toxicol. 2017 Jan;67:149-164. doi: 10.1016/j.reprotox.2017.01.005. Epub 2017 Jan 11. Review.

PMID:
28088501
20.

Adrenal failure due to bilateral adrenal metastasis of rectal cancer: A case report.

Imaoka Y, Kuranishi F, Ogawa Y, Okuda H, Nakahara M.

Int J Surg Case Rep. 2017;31:1-4. doi: 10.1016/j.ijscr.2016.12.011. Epub 2016 Dec 21.

21.

LRGUK1 is part of a multiprotein complex required for manchette function and male fertility.

Okuda H, DeBoer K, O'Connor AE, Merriner DJ, Jamsai D, O'Bryan MK.

FASEB J. 2017 Mar;31(3):1141-1152. doi: 10.1096/fj.201600909R. Epub 2016 Dec 21.

PMID:
28003339
22.
23.

Radiofrequency Ablation Guided by Contrast-Enhanced Sonography versus B-Mode Sonography for Hepatocellular Carcinoma after Transcatheter Arterial Chemoembolization.

Kawasaki T, Hata KY, Kinoshita D, Takayama M, Okuda H, Mizuno S, Kudo M.

Dig Dis. 2016;34(6):692-695. Epub 2016 Oct 17.

PMID:
27750239
24.

Randomized study of FOLFIRI plus either panitumumab or bevacizumab for wild-type KRAS colorectal cancer-WJOG 6210G.

Shitara K, Yonesaka K, Denda T, Yamazaki K, Moriwaki T, Tsuda M, Takano T, Okuda H, Nishina T, Sakai K, Nishio K, Tokunaga S, Yamanaka T, Boku N, Hyodo I, Muro K.

Cancer Sci. 2016 Dec;107(12):1843-1850. doi: 10.1111/cas.13098.

25.

Changes in endothelial cell proliferation and vascular permeability after systemic lipopolysaccharide administration in the subfornical organ.

Morita-Takemura S, Nakahara K, Tatsumi K, Okuda H, Tanaka T, Isonishi A, Wanaka A.

J Neuroimmunol. 2016 Sep 15;298:132-7. doi: 10.1016/j.jneuroim.2016.06.011. Epub 2016 Jul 1.

PMID:
27609286
26.

TBP loading by AF4 through SL1 is the major rate-limiting step in MLL fusion-dependent transcription.

Okuda H, Takahashi S, Takaori-Kondo A, Yokoyama A.

Cell Cycle. 2016 Oct 17;15(20):2712-22. doi: 10.1080/15384101.2016.1222337. Epub 2016 Aug 26.

27.

Occupational Exposure Limits of lead, dimethylamine, n-butyl-2,3-epoxypropyl ether, and 2-ethyl-1-hexanol and carcinogenicity and occupational sensitizer classification.

Committee for Recommendation of Occupational Exposure Limits, Japan Society for Occupational Health, Azuma K, Endo G, Endo Y, Hara K, Harada K, Hori H, Horie S, Horiguchi H, Ichiba M, Ichihara G, Ikeda M, Ishitake T, Ito A, Iwasawa S, Kamijima M, Karita K, Kawai T, Kawamoto T, Koizumi A, Kumagai S, Kusaka Y, Miyagawa M, Morimoto Y, Nagano K, Nasu T, Nomiyama T, Omae K, Sato K, Okuda H, Sakurai H, Sobue T, Suwazono Y, Takebayashi T, Takeshita T, Takeuchi A, Tanaka M, Tanaka S, Tsukahara T, Tsunoda M, Ueno S, Yamano Y, Yamauchi T, Yano E.

J Occup Health. 2016 Sep 13;58(4 Spec No):385-7. doi: 10.1539/joh.16-0155-OP. Epub 2016 Jul 30. No abstract available.

28.

Voluntary Exercise Induces Astrocytic Structural Plasticity in the Globus Pallidus.

Tatsumi K, Okuda H, Morita-Takemura S, Tanaka T, Isonishi A, Shinjo T, Terada Y, Wanaka A.

Front Cell Neurosci. 2016 Jun 21;10:165. doi: 10.3389/fncel.2016.00165. eCollection 2016.

29.

Assessment of cancer pain in a patient with communication difficulties: a case report.

Okimasa S, Saito Y, Okuda H, Fukuda T, Yano M, Okamoto Y, Ono E, Ohdan H.

J Med Case Rep. 2016 Jun 2;10(1):148. doi: 10.1186/s13256-016-0935-2.

30.

Hedgehog Signaling Components Are Expressed in Choroidal Neovascularization in Laser-induced Retinal Lesion.

Nochioka K, Okuda H, Tatsumi K, Morita S, Ogata N, Wanaka A.

Acta Histochem Cytochem. 2016 Apr 28;49(2):67-74. doi: 10.1267/ahc.15036. Epub 2016 Apr 9.

31.

Atomic Force Microscopic Analysis of the Effect of Lipid Composition on Liposome Membrane Rigidity.

Takechi-Haraya Y, Sakai-Kato K, Abe Y, Kawanishi T, Okuda H, Goda Y.

Langmuir. 2016 Jun 21;32(24):6074-82. doi: 10.1021/acs.langmuir.6b00741. Epub 2016 Jun 9.

PMID:
27232007
32.

Infantile Pain Episodes Associated with Novel Nav1.9 Mutations in Familial Episodic Pain Syndrome in Japanese Families.

Okuda H, Noguchi A, Kobayashi H, Kondo D, Harada KH, Youssefian S, Shioi H, Kabata R, Domon Y, Kubota K, Kitano Y, Takayama Y, Hitomi T, Ohno K, Saito Y, Asano T, Tominaga M, Takahashi T, Koizumi A.

PLoS One. 2016 May 25;11(5):e0154827. doi: 10.1371/journal.pone.0154827. eCollection 2016.

33.

WNT7A Regulation by miR-15b in Ovarian Cancer.

MacLean JA 2nd, King ML, Okuda H, Hayashi K.

PLoS One. 2016 May 19;11(5):e0156109. doi: 10.1371/journal.pone.0156109. eCollection 2016.

34.

Analysis of lipoprotein profiles of healthy cats by gel-permeation high-performance liquid chromatography.

Mizutani H, Sako T, Okuda H, Arai N, Kuriyama K, Mori A, Yoshimura I, Koyama H.

J Vet Med Sci. 2016 Sep 1;78(8):1277-81. doi: 10.1292/jvms.16-0052. Epub 2016 May 7.

35.

Observation of liposomes of differing lipid composition in aqueous medium by means of atomic force microscopy.

Takechi-Haraya Y, Sakai-Kato K, Abe Y, Kawanishi T, Okuda H, Goda Y.

Microscopy (Oxf). 2016 Aug;65(4):383-9. doi: 10.1093/jmicro/dfw011. Epub 2016 Mar 28.

PMID:
27020464
36.

Serum HER2 as an adjunct to assess HER2 status for advanced gastric cancer: A prospective multicenter trial (SHERLOCK).

Saito M, Yamashita K, Arimura Y, Kaneto H, Okuda H, Nojima M, Hagiwara T, Suzuki K, Adachi T, Goto A, Nakachi K, Yawata A, Yoshimoto M, Tanuma T, Adachi Y, Yamaoka S, Mizukoshi T, Kawayama M, Hamamoto Y, Shinomura Y.

Acta Oncol. 2016;55(3):309-17. doi: 10.3109/0284186X.2015.1107189. Epub 2016 Jan 12.

PMID:
26757197
37.

Direct Interaction between the Voltage Sensors Produces Cooperative Sustained Deactivation in Voltage-gated H+ Channel Dimers.

Okuda H, Yonezawa Y, Takano Y, Okamura Y, Fujiwara Y.

J Biol Chem. 2016 Mar 11;291(11):5935-47. doi: 10.1074/jbc.M115.666834. Epub 2016 Jan 11.

38.

Biological Monitoring of Human Exposure to Neonicotinoids Using Urine Samples, and Neonicotinoid Excretion Kinetics.

Harada KH, Tanaka K, Sakamoto H, Imanaka M, Niisoe T, Hitomi T, Kobayashi H, Okuda H, Inoue S, Kusakawa K, Oshima M, Watanabe K, Yasojima M, Takasuga T, Koizumi A.

PLoS One. 2016 Jan 5;11(1):e0146335. doi: 10.1371/journal.pone.0146335. eCollection 2016.

39.

Hedgehog Signaling Modulates the Release of Gliotransmitters from Cultured Cerebellar Astrocytes.

Okuda H, Tatsumi K, Morita-Takemura S, Nakahara K, Nochioka K, Shinjo T, Terada Y, Wanaka A.

Neurochem Res. 2016 Feb;41(1-2):278-89. doi: 10.1007/s11064-015-1791-y. Epub 2015 Dec 22.

PMID:
26694649
40.

AF4 uses the SL1 components of RNAP1 machinery to initiate MLL fusion- and AEP-dependent transcription.

Okuda H, Kanai A, Ito S, Matsui H, Yokoyama A.

Nat Commun. 2015 Nov 23;6:8869. doi: 10.1038/ncomms9869.

41.

Interaction kinetics of serum proteins with liposomes and their effect on phospholipase-induced liposomal drug release.

Shibata H, Yoshida H, Izutsu K, Haishima Y, Kawanishi T, Okuda H, Goda Y.

Int J Pharm. 2015 Nov 30;495(2):827-39. doi: 10.1016/j.ijpharm.2015.09.053. Epub 2015 Sep 26.

PMID:
26410758
42.

Nanoclusters first: a hierarchical phase transformation in a novel Mg alloy.

Okuda H, Yamasaki M, Kawamura Y, Tabuchi M, Kimizuka H.

Sci Rep. 2015 Sep 21;5:14186. doi: 10.1038/srep14186.

43.

Analysis of Distribution of Ingredients in Commercially Available Clarithromycin Tablets Using Near-Infrared Chemical Imaging with Principal Component Analysis and Partial Least Squares.

Koide T, Yamamoto Y, Fukami T, Katori N, Okuda H, Hiyama Y.

Chem Pharm Bull (Tokyo). 2015;63(9):663-8. doi: 10.1248/cpb.c14-00811.

44.

Effects of lipid composition on the properties of doxorubicin-loaded liposomes.

Sakai-Kato K, Nanjo K, Kawanishi T, Okuda H, Goda Y.

Ther Deliv. 2015 Jul;6(7):785-94. doi: 10.4155/tde.15.29.

PMID:
26228772
45.

Portable hyperspectral imager with continuous wave green laser for identification and detection of untreated latent fingerprints on walls.

Nakamura A, Okuda H, Nagaoka T, Akiba N, Kurosawa K, Kuroki K, Ichikawa F, Torao A, Sota T.

Forensic Sci Int. 2015 Sep;254:100-5. doi: 10.1016/j.forsciint.2015.06.031. Epub 2015 Jul 8.

PMID:
26207675
46.

Effect of Knockout of Mdr1a and Mdr1b ABCB1 Genes on the Systemic Exposure of a Doxorubicin-Conjugated Block Copolymer in Mice.

Sakai-Kato K, Nanjo K, Kusuhara H, Nishiyama N, Kataoka K, Kawanishi T, Okuda H, Goda Y.

Mol Pharm. 2015 Sep 8;12(9):3175-83. doi: 10.1021/acs.molpharmaceut.5b00234. Epub 2015 Aug 5.

PMID:
26194248
47.

Biochemical and Functional Characterization of RNF213 (Mysterin) R4810K, a Susceptibility Mutation of Moyamoya Disease, in Angiogenesis In Vitro and In Vivo.

Kobayashi H, Matsuda Y, Hitomi T, Okuda H, Shioi H, Matsuda T, Imai H, Sone M, Taura D, Harada KH, Habu T, Takagi Y, Miyamoto S, Koizumi A.

J Am Heart Assoc. 2015 Jun 30;4(7). pii: e002146. doi: 10.1161/JAHA.115.002146.

48.

Heterogeneous vascular permeability and alternative diffusion barrier in sensory circumventricular organs of adult mouse brain.

Morita S, Furube E, Mannari T, Okuda H, Tatsumi K, Wanaka A, Miyata S.

Cell Tissue Res. 2016 Feb;363(2):497-511. doi: 10.1007/s00441-015-2207-7. Epub 2015 Jun 6.

PMID:
26048259
49.

Japanese bioanalytical method validation guideline: the world's first regulatory guideline dedicated to ligand-binding assays.

Imazato-Hirano M, Taniguchi Y, Kakehi M, Kuze Y, Nakamura T, Minamide Y, Miya K, Hosogi J, Katashima M, Maekawa K, Okuda H, Niimi S, Kawasaki N, Ishii-Watabe A, Katori N.

Bioanalysis. 2015;7(9):1151-6. doi: 10.4155/bio.15.43. No abstract available.

PMID:
26039811
50.

Exact helical polymer synthesis by a two-point-covalent-linking protocol between C2-chiral spirobifluorene and C2- or C(s)-symmetric anthraquinone monomers.

Yi Z, Okuda H, Koyama Y, Seto R, Uchida S, Sogawa H, Kuwata S, Takata T.

Chem Commun (Camb). 2015 Jul 4;51(52):10423-6. doi: 10.1039/c5cc02086g.

PMID:
26028037

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