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Items: 1 to 50 of 80

1.

Influence of CYP2D6, CYP3A4, CYP3A5 and ABCB1 Polymorphisms on Pharmacokinetics and Safety of Aripiprazole in Healthy Volunteers.

Belmonte C, Ochoa D, Román M, Saiz-Rodríguez M, Wojnicz A, Gómez-Sánchez CI, Martín-Vílchez S, Abad-Santos F.

Basic Clin Pharmacol Toxicol. 2018 Jan 11. doi: 10.1111/bcpt.12960. [Epub ahead of print]

PMID:
29325225
2.

Effective phospholipids removing microelution-solid phase extraction LC-MS/MS method for simultaneous plasma quantification of aripiprazole and dehydro-aripiprazole: Application to human pharmacokinetic studies.

Wojnicz A, Belmonte C, Koller D, Ruiz-Nuño A, Román M, Ochoa D, Abad-Santos F.

J Pharm Biomed Anal. 2018 Mar 20;151:116-125. doi: 10.1016/j.jpba.2017.12.049. Epub 2017 Dec 28.

PMID:
29324280
3.

Evolution, dynamics and dysregulation of kinase signalling.

Ochoa D, Bradley D, Beltrao P.

Curr Opin Struct Biol. 2018 Jan 6;48:133-140. doi: 10.1016/j.sbi.2017.12.008. [Epub ahead of print] Review.

PMID:
29316484
4.

Polymorphisms associated with adalimumab and infliximab response in moderate-to-severe plaque psoriasis.

Ovejero-Benito MC, Prieto-Pérez R, Llamas-Velasco M, Muñoz-Aceituno E, Reolid A, Saiz-Rodríguez M, Belmonte C, Román M, Ochoa D, Talegón M, Cabaleiro T, Daudén E, Abad-Santos F.

Pharmacogenomics. 2018 Jan;19(1):7-16. doi: 10.2217/pgs-2017-0143. Epub 2017 Dec 1.

PMID:
29192552
5.

Effect of Polymorphisms on the Pharmacokinetics, Pharmacodynamics and Safety of Sertraline in Healthy Volunteers.

Saiz-Rodríguez M, Belmonte C, Román M, Ochoa D, Koller D, Talegón M, Ovejero-Benito MC, López-Rodríguez R, Cabaleiro T, Abad-Santos F.

Basic Clin Pharmacol Toxicol. 2017 Nov 14. doi: 10.1111/bcpt.12938. [Epub ahead of print]

PMID:
29136336
6.

Pharmacogenetics of trazodone in healthy volunteers: association with pharmacokinetics, pharmacodynamics and safety.

Saiz-Rodríguez M, Belmonte C, Derqui-Fernández N, Cabaleiro T, Román M, Ochoa D, Talegón M, Ovejero-Benito MC, Abad-Santos F.

Pharmacogenomics. 2017 Nov;18(16):1491-1502. doi: 10.2217/pgs-2017-0116. Epub 2017 Oct 24.

PMID:
29061081
7.

A Pilot Trial of a Lifestyle Intervention for Stroke Survivors: Design of Healthy Eating and Lifestyle after Stroke (HEALS).

Hill VA, Vickrey BG, Cheng EM, Valle NP, Ayala-Rivera M, Moreno L, Munoz C, Dombish H, Espinosa A, Wang D, Ochoa D, Chu A, Heymann R, Towfighi A.

J Stroke Cerebrovasc Dis. 2017 Dec;26(12):2806-2813. doi: 10.1016/j.jstrokecerebrovasdis.2017.06.058. Epub 2017 Aug 16.

PMID:
28823491
8.

Connective Tissue Growth Factor Promotes Efficient Generation of Human Induced Pluripotent Stem Cell-Derived Choroidal Endothelium.

Songstad AE, Worthington KS, Chirco KR, Giacalone JC, Whitmore SS, Anfinson KR, Ochoa D, Cranston CM, Riker MJ, Neiman M, Stone EM, Mullins RF, Tucker BA.

Stem Cells Transl Med. 2017 Jun;6(6):1533-1546. doi: 10.1002/sctm.16-0399. Epub 2017 May 5.

9.

Polymorphisms associated with etanercept response in moderate-to-severe plaque psoriasis.

Ovejero-Benito MC, Prieto-Pérez R, Llamas-Velasco M, Belmonte C, Cabaleiro T, Román M, Ochoa D, Talegón M, Saiz-Rodríguez M, Daudén E, Abad-Santos F.

Pharmacogenomics. 2017 May;18(7):631-638. doi: 10.2217/pgs-2017-0014. Epub 2017 May 4.

PMID:
28470127
10.

Epigenetic biomarkers associated with antitumour necrosis factor drug response in moderate-to-severe psoriasis.

Ovejero-Benito MC, Cabaleiro T, Sanz-García A, Llamas-Velasco M, Saiz-Rodríguez M, Prieto-Pérez R, Talegón M, Román M, Ochoa D, Reolid A, Daudén E, Abad-Santos F.

Br J Dermatol. 2017 Mar 30. doi: 10.1111/bjd.15504. [Epub ahead of print] No abstract available.

PMID:
28369750
11.

Nutrition and physical activity transitions in the Ecuadorian Andes: Differences among urban and rural-dwelling women.

Melby CL, Orozco F, Ochoa D, Muquinche M, Padro M, Munoz FN.

Am J Hum Biol. 2017 Jul 8;29(4). doi: 10.1002/ajhb.22986. Epub 2017 Mar 1.

PMID:
28247963
12.

Benchmarking substrate-based kinase activity inference using phosphoproteomic data.

Hernandez-Armenta C, Ochoa D, Gonçalves E, Saez-Rodriguez J, Beltrao P.

Bioinformatics. 2017 Jun 15;33(12):1845-1851. doi: 10.1093/bioinformatics/btx082.

PMID:
28200105
13.

Systematic Analysis of Transcriptional and Post-transcriptional Regulation of Metabolism in Yeast.

Gonçalves E, Raguz Nakic Z, Zampieri M, Wagih O, Ochoa D, Sauer U, Beltrao P, Saez-Rodriguez J.

PLoS Comput Biol. 2017 Jan 10;13(1):e1005297. doi: 10.1371/journal.pcbi.1005297. eCollection 2017 Jan.

14.

Awareness, Comprehension, and Use of Newly Mandated Nutrition Labels Among Mestiza and Indigenous Ecuadorian Women in the Central Andes Region of Ecuador.

Orozco F, Ochoa D, Muquinche M, Padro M, Melby CL.

Food Nutr Bull. 2016 Jan 1:379572116684730. doi: 10.1177/0379572116684730. [Epub ahead of print]

PMID:
28013557
15.

Pharmacogenetics of ustekinumab in patients with moderate-to-severe plaque psoriasis.

Prieto-Pérez R, Llamas-Velasco M, Cabaleiro T, Solano-López G, Márquez B, Román M, Ochoa D, Talegón M, Daudén E, Abad-Santos F.

Pharmacogenomics. 2017 Jan;18(2):157-164. doi: 10.2217/pgs-2016-0122. Epub 2016 Dec 15.

PMID:
27977334
16.

An atlas of human kinase regulation.

Ochoa D, Jonikas M, Lawrence RT, El Debs B, Selkrig J, Typas A, Villén J, Santos SD, Beltrao P.

Mol Syst Biol. 2016 Dec 1;12(12):888. doi: 10.15252/msb.20167295.

17.

Evaluation of the Relationship Between Pharmacokinetics and the Safety of Aripiprazole and Its Cardiovascular Effects in Healthy Volunteers.

Belmonte C, Ochoa D, Román M, Cabaleiro T, Talegón M, Sánchez-Rojas SD, Abad-Santos F.

J Clin Psychopharmacol. 2016 Dec;36(6):608-614.

18.

New polymorphisms associated with response to anti-TNF drugs in patients with moderate-to-severe plaque psoriasis.

Prieto-Pérez R, Solano-López G, Cabaleiro T, Román M, Ochoa D, Talegón M, Baniandrés O, López-Estebaranz JL, de la Cueva P, Daudén E, Abad-Santos F.

Pharmacogenomics J. 2018 Jan;18(1):70-75. doi: 10.1038/tpj.2016.64. Epub 2016 Sep 27.

PMID:
27670765
19.

Using Patient-Specific Induced Pluripotent Stem Cells and Wild-Type Mice to Develop a Gene Augmentation-Based Strategy to Treat CLN3-Associated Retinal Degeneration.

Wiley LA, Burnight ER, Drack AV, Banach BB, Ochoa D, Cranston CM, Madumba RA, East JS, Mullins RF, Stone EM, Tucker BA.

Hum Gene Ther. 2016 Oct;27(10):835-846. doi: 10.1089/hum.2016.049. Epub 2016 Jul 11.

20.

Does Axillary Reverse Mapping Prevent Lymphedema After Lymphadenectomy?

Tummel E, Ochoa D, Korourian S, Betzold R, Adkins L, McCarthy M, Hung S, Kalkwarf K, Gallagher K, Lee JY, Klimberg VS.

Ann Surg. 2017 May;265(5):987-992. doi: 10.1097/SLA.0000000000001778.

PMID:
27163955
21.

Epigenomic Co-localization and Co-evolution Reveal a Key Role for 5hmC as a Communication Hub in the Chromatin Network of ESCs.

Juan D, Perner J, Carrillo de Santa Pau E, Marsili S, Ochoa D, Chung HR, Vingron M, Rico D, Valencia A.

Cell Rep. 2016 Feb 9;14(5):1246-1257. doi: 10.1016/j.celrep.2016.01.008. Epub 2016 Jan 28.

22.

Utility of Pilot Studies for Predicting Ratios and Intrasubject Variability in High-Variability Drugs.

Moreno I, Ochoa D, Román M, Cabaleiro T, Abad-Santos F.

Basic Clin Pharmacol Toxicol. 2016 Aug;119(2):215-21. doi: 10.1111/bcpt.12558. Epub 2016 Feb 9.

23.

Polymorphisms Associated with Age at Onset in Patients with Moderate-to-Severe Plaque Psoriasis.

Prieto-Pérez R, Solano-López G, Cabaleiro T, Román M, Ochoa D, Talegón M, Baniandrés O, López-Estebaranz JL, de la Cueva P, Daudén E, Abad-Santos F.

J Immunol Res. 2015;2015:101879. doi: 10.1155/2015/101879. Epub 2015 Nov 3.

24.

The polymorphism rs763780 in the IL-17F gene is associated with response to biological drugs in patients with psoriasis.

Prieto-Pérez R, Solano-López G, Cabaleiro T, Román M, Ochoa D, Talegón M, Baniandrés O, López Estebaranz JL, de la Cueva P, Daudén E, Abad-Santos F.

Pharmacogenomics. 2015;16(15):1723-31. doi: 10.2217/pgs.15.107. Epub 2015 Sep 29.

PMID:
26415694
25.

Effect of Chondroitin Sulphate on Pro-Inflammatory Mediators and Disease Activity in Patients with Inflammatory Bowel Disease.

Linares PM, Chaparro M, Algaba A, Román M, Moreno Arza I, Abad Santos F, Ochoa D, Guerra I, Bermejo F, Gisbert JP.

Digestion. 2015;92(4):203-10. doi: 10.1159/000439522. Epub 2015 Sep 19.

PMID:
26381879
26.

High Prolactin Excretion in Patients with Diabetes Mellitus and Impaired Renal Function.

Triebel J, Moreno-Vega AI, Vázquez-Membrillo M, Nava G, García-Franco R, López-Star E, Baldivieso-Hurtado O, Ochoa D, Macotela Y, Bertsch T, Martinez de la Escalera G, Clapp C.

Clin Lab. 2015;61(7):709-16.

PMID:
26299069
27.

Paradoxical psoriasiform reactions to anti-TNFα drugs are associated with genetic polymorphisms in patients with psoriasis.

Cabaleiro T, Prieto-Pérez R, Navarro R, Solano G, Román M, Ochoa D, Abad-Santos F, Daudén E.

Pharmacogenomics J. 2016 Aug;16(4):336-40. doi: 10.1038/tpj.2015.53. Epub 2015 Jul 21.

PMID:
26194362
28.

Effect of gender and CYP2C9 and CYP2C8 polymorphisms on the pharmacokinetics of ibuprofen enantiomers.

Ochoa D, Prieto-Pérez R, Román M, Talegón M, Rivas A, Galicia I, Abad-Santos F, Cabaleiro T.

Pharmacogenomics. 2015;16(9):939-48. doi: 10.2217/pgs.15.40. Epub 2015 Jun 30.

PMID:
26122864
29.

Effect of Truncating AUC at 12, 24 and 48 hr When Evaluating the Bioequivalence of Drugs with a Long Half-Life.

Moreno I, Ochoa D, Román M, Cabaleiro T, Abad-Santos F.

Basic Clin Pharmacol Toxicol. 2016 Jan;118(1):53-7. doi: 10.1111/bcpt.12432. Epub 2015 Jul 14.

30.

Kinase-two-hybrid: towards the conditional interactome.

Ochoa D, Beltrao P.

Mol Syst Biol. 2015 Mar 26;11(3):798. doi: 10.15252/msb.20156107.

31.

The SAVE review: sonographic analysis versus excision for axillary staging in breast cancer.

Henry-Tillman R, Glover-Collins K, Preston M, Gallagher K, Tummel E, Robertson YV, Ochoa D, Korourian S, Westbrook K, Klimberg VS.

J Am Coll Surg. 2015 Apr;220(4):560-7. doi: 10.1016/j.jamcollsurg.2014.12.033. Epub 2015 Jan 28.

PMID:
25797740
32.

Detection of significant protein coevolution.

Ochoa D, Juan D, Valencia A, Pazos F.

Bioinformatics. 2015 Jul 1;31(13):2166-73. doi: 10.1093/bioinformatics/btv102. Epub 2015 Feb 24.

PMID:
25717190
33.

New immune system genetic polymorphisms associated with moderate-to-severe plaque psoriasis: a case-control study.

Prieto-Pérez R, Solano-López G, Cabaleiro T, Román M, Ochoa D, Talegón M, Baniandrés O, Estebaranz JL, de la Cueva P, Daudén E, Abad-Santos F.

Br J Dermatol. 2015;172(5):1432-5. doi: 10.1111/bjd.13585. Epub 2015 Mar 18. No abstract available.

PMID:
25639754
34.

Evaluation of the relationship between polymorphisms in CYP2C19 and the pharmacokinetics of omeprazole, pantoprazole and rabeprazole.

Román M, Ochoa D, Sánchez-Rojas SD, Talegón M, Prieto-Pérez R, Rivas Â, Abad-Santos F, Cabaleiro T.

Pharmacogenomics. 2014;15(15):1893-901. doi: 10.2217/pgs.14.141.

PMID:
25495411
35.

Axillary reverse mapping: five-year experience.

Ochoa D, Korourian S, Boneti C, Adkins L, Badgwell B, Klimberg VS.

Surgery. 2014 Nov;156(5):1261-8. doi: 10.1016/j.surg.2014.05.011. Epub 2014 Oct 17.

36.

Practical aspects of protein co-evolution.

Ochoa D, Pazos F.

Front Cell Dev Biol. 2014 Apr 22;2:14. doi: 10.3389/fcell.2014.00014. eCollection 2014. Review.

37.

Advanced locoregional therapies in breast.

Mitchell S, Klimberg VS, Ochoa D, Rusby J, Chang D, Patel R, Park J, Korn JM, Djohan R.

Ann Surg Oncol. 2014 Oct;21(10):3198-203. doi: 10.1245/s10434-014-3916-y. Epub 2014 Jul 30.

PMID:
25074662
38.

Effect of polymorphisms on the pharmacokinetics, pharmacodynamics, and safety of risperidone in healthy volunteers.

Cabaleiro T, Ochoa D, López-Rodríguez R, Román M, Novalbos J, Ayuso C, Abad-Santos F.

Hum Psychopharmacol. 2014 Sep;29(5):459-69. Erratum in: Hum Psychopharmacol. 2015 Nov;30(6):451.

PMID:
25042870
39.

Pharmacogenetics of quetiapine in healthy volunteers: association with pharmacokinetics, pharmacodynamics, and adverse effects.

Cabaleiro T, López-Rodríguez R, Román M, Ochoa D, Novalbos J, Borobia A, Carcas A, Abad-Santos F.

Int Clin Psychopharmacol. 2015 Mar;30(2):82-8. doi: 10.1097/YIC.0000000000000047.

PMID:
25025989
40.

Polymorphisms in CYP2D6 have a greater effect on variability of risperidone pharmacokinetics than gender.

Cabaleiro T, Ochoa D, Román M, Moreno I, López-Rodríguez R, Novalbos J, Abad-Santos F.

Basic Clin Pharmacol Toxicol. 2015 Feb;116(2):124-8. doi: 10.1111/bcpt.12286. Epub 2014 Jul 25.

41.

Long-term results of phase II ablation after breast lumpectomy added to extend intraoperative margins (ABLATE l) trial.

Klimberg VS, Ochoa D, Henry-Tillman R, Hardee M, Boneti C, Adkins LL, McCarthy M, Tummel E, Lee J, Malak S, Makhoul I, Korourian S.

J Am Coll Surg. 2014 Apr;218(4):741-9. doi: 10.1016/j.jamcollsurg.2013.12.032. Epub 2014 Jan 11.

PMID:
24655863
42.

Surgeon-performed touch preparation of breast core needle biopsies may provide accurate same-day diagnosis and expedite treatment planning.

Gadgil PV, Korourian S, Malak S, Ochoa D, Lipschitz R, Henry-Tillman R, Suzanne Klimberg V.

Ann Surg Oncol. 2014 Apr;21(4):1215-21. doi: 10.1245/s10434-013-3440-5. Epub 2013 Dec 31.

PMID:
24378986
43.

Importance of ancillary supplies for subcutaneous immunoglobulin infusion: management of the local infusion site.

Duff C, Ochoa D, Riley P, Murphy E, Zampelli A.

J Infus Nurs. 2013 Nov-Dec;36(6):384-90. doi: 10.1097/NAN.0000000000000009.

PMID:
24202117
44.

Association between psoriasis and polymorphisms in the TNF, IL12B, and IL23R genes in Spanish patients.

Cabaleiro T, Román M, Gallo E, Ochoa D, Tudelilla F, Talegón M, Prieto-Pérez R, García-Díez A, Daudén E, Abad-Santos F.

Eur J Dermatol. 2013 Sep-Oct;23(5):640-5. doi: 10.1684/ejd.2013.2144.

PMID:
24135300
45.

Pharmacogenetics of topical and systemic treatment of psoriasis.

Prieto-Pérez R, Cabaleiro T, Daudén E, Ochoa D, Román M, Abad-Santos F.

Pharmacogenomics. 2013 Oct;14(13):1623-34. doi: 10.2217/pgs.13.163. Review.

PMID:
24088133
46.

Genetics of psoriasis and pharmacogenetics of biological drugs.

Prieto-Pérez R, Cabaleiro T, Daudén E, Ochoa D, Roman M, Abad-Santos F.

Autoimmune Dis. 2013;2013:613086. doi: 10.1155/2013/613086. Epub 2013 Aug 28. Review.

47.

Evaluation of the relationship between polymorphisms in CYP2C8 and CYP2C9 and the pharmacokinetics of celecoxib.

Prieto-Pérez R, Ochoa D, Cabaleiro T, Román M, Sánchez-Rojas SD, Talegón M, Abad-Santos F.

J Clin Pharmacol. 2013 Dec;53(12):1261-7. doi: 10.1002/jcph.169. Epub 2013 Sep 17.

PMID:
23996211
48.

Nipple skin-sparing mastectomy is feasible for advanced disease.

Burdge EC, Yuen J, Hardee M, Gadgil PV, Das C, Henry-Tillman R, Ochoa D, Korourian S, Suzanne Klimberg V.

Ann Surg Oncol. 2013 Oct;20(10):3294-302. doi: 10.1245/s10434-013-3174-4. Epub 2013 Aug 22.

PMID:
23975304
49.

Pharmacodynamic genetic variants related to antipsychotic adverse reactions in healthy volunteers.

López-Rodríguez R, Cabaleiro T, Ochoa D, Román M, Borobia AM, Carcas AJ, Ayuso C, Novalbos J, Abad-Santos F.

Pharmacogenomics. 2013 Jul;14(10):1203-14. doi: 10.2217/pgs.13.106.

PMID:
23859574
50.

[Application of pharmacogenomics and other new technologies to drug development].

Cabaleiro T, Prieto-Pérez R, Ochoa D, Abad-Santos F.

Med Clin (Barc). 2013 Jun 18;140(12):558-63. doi: 10.1016/j.medcli.2013.02.010. Epub 2013 Apr 10. Spanish. No abstract available.

PMID:
23582104

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