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Items: 1 to 50 of 61

1.

Tomatoes protect against development of UV-induced keratinocyte carcinoma via metabolomic alterations.

Cooperstone JL, Tober KL, Riedl KM, Teegarden MD, Cichon MJ, Francis DM, Schwartz SJ, Oberyszyn TM.

Sci Rep. 2017 Jul 11;7(1):5106. doi: 10.1038/s41598-017-05568-7.

2.

Transcriptional regulation of ataxia-telangiectasia and Rad3-related protein by activated p21-activated kinase-1 protects keratinocytes in UV-B-induced premalignant skin lesions.

Beesetti S, Mavuluri J, Surabhi RP, Oberyszyn TM, Tober K, Pitani RS, Joseph LD, Venkatraman G, Rayala SK.

Oncogene. 2017 Nov 2;36(44):6154-6163. doi: 10.1038/onc.2017.218. Epub 2017 Jul 10.

PMID:
28692051
3.

25-Hydroxyvitamin D3 and its C-3 epimer are elevated in the skin and serum of Skh-1 mice supplemented with dietary vitamin D3.

Teegarden MD, Campbell AR, Cooperstone JL, Tober KL, Schwartz SJ, Oberyszyn TM.

Mol Nutr Food Res. 2017 Oct;61(10). doi: 10.1002/mnfr.201700293. Epub 2017 Jul 20.

PMID:
28589636
4.

Ultraviolet radiation accelerates NRas-mutant melanomagenesis: A cooperative effect blocked by sunscreen.

Hennessey RC, Holderbaum AM, Bonilla A, Delaney C, Gillahan JE, Tober KL, Oberyszyn TM, Zippin JH, Burd CE.

Pigment Cell Melanoma Res. 2017 Sep;30(5):477-487. doi: 10.1111/pcmr.12601. Epub 2017 Jul 4.

PMID:
28544727
5.

Cyclosporine A immunosuppression drives catastrophic squamous cell carcinoma through IL-22.

Abikhair M, Mitsui H, Yanofsky V, Roudiani N, Ovits C, Bryan T, Oberyszyn TM, Tober KL, Gonzalez J, Krueger JG, Felsen D, Carucci JA.

JCI Insight. 2016 Jun 2;1(8):e86434.

6.

Sex differences in skin carotenoid deposition and acute UVB-induced skin damage in SKH-1 hairless mice after consumption of tangerine tomatoes.

Kopec RE, Schick J, Tober KL, Riedl KM, Francis DM, Young GS, Schwartz SJ, Oberyszyn TM.

Mol Nutr Food Res. 2015 Dec;59(12):2491-501. doi: 10.1002/mnfr.201500317. Epub 2015 Oct 20.

7.

Endogenous Retinoic Acid Required to Maintain the Epidermis Following Ultraviolet Light Exposure in SKH-1 Hairless Mice.

Gressel KL, Duncan FJ, Oberyszyn TM, La Perle KM, Everts HB.

Photochem Photobiol. 2015 Jul-Aug;91(4):901-8. doi: 10.1111/php.12441. Epub 2015 Mar 28.

8.

Role of vitamin D3 in modulation of ΔNp63α expression during UVB induced tumor formation in SKH-1 mice.

Hill NT, Gracia-Maldonado GH, Leonard MK, Harper AR, Tober KL, Oberyszyn TM, Kadakia MP.

PLoS One. 2014 Sep 5;9(9):e107052. doi: 10.1371/journal.pone.0107052. eCollection 2014.

9.

Isothiocyanate metabolism, distribution, and interconversion in mice following consumption of thermally processed broccoli sprouts or purified sulforaphane.

Bricker GV, Riedl KM, Ralston RA, Tober KL, Oberyszyn TM, Schwartz SJ.

Mol Nutr Food Res. 2014 Oct;58(10):1991-2000. doi: 10.1002/mnfr.201400104. Epub 2014 Jul 28.

10.

MIF antagonist (CPSI-1306) protects against UVB-induced squamous cell carcinoma.

Nagarajan P, Tober KL, Riggenbach JA, Kusewitt DF, Lehman AM, Sielecki T, Pruitt J, Satoskar AR, Oberyszyn TM.

Mol Cancer Res. 2014 Sep;12(9):1292-302. doi: 10.1158/1541-7786.MCR-14-0255-T. Epub 2014 May 21.

11.

Extended UVB Exposures Alter Tumorigenesis and Treatment Efficacy in a Murine Model of Cutaneous Squamous Cell Carcinoma.

Burns EM, Tober KL, Riggenbach JA, Kusewitt DF, Young GS, Oberyszyn TM.

J Skin Cancer. 2013;2013:246848. doi: 10.1155/2013/246848. Epub 2013 Oct 27.

12.

Slug expression in mouse skin and skin tumors is not regulated by p53.

Perez CJ, Rundhaug JE, Johnson DG, Oberyszyn TM, Tober KL, Kusewitt DF.

J Invest Dermatol. 2014 Feb;134(2):566-568. doi: 10.1038/jid.2013.363. Epub 2013 Sep 5. No abstract available.

13.

Ultraviolet light exposure stimulates HMGB1 release by keratinocytes.

Johnson KE, Wulff BC, Oberyszyn TM, Wilgus TA.

Arch Dermatol Res. 2013 Nov;305(9):805-15. doi: 10.1007/s00403-013-1401-2. Epub 2013 Aug 13.

14.

Differential effects of topical vitamin E and C E Ferulic® treatments on ultraviolet light B-induced cutaneous tumor development in Skh-1 mice.

Burns EM, Tober KL, Riggenbach JA, Kusewitt DF, Young GS, Oberyszyn TM.

PLoS One. 2013 May 14;8(5):e63809. doi: 10.1371/journal.pone.0063809. Print 2013.

15.

Preventative topical diclofenac treatment differentially decreases tumor burden in male and female Skh-1 mice in a model of UVB-induced cutaneous squamous cell carcinoma.

Burns EM, Tober KL, Riggenbach JA, Schick JS, Lamping KN, Kusewitt DF, Young GS, Oberyszyn TM.

Carcinogenesis. 2013 Feb;34(2):370-7. doi: 10.1093/carcin/bgs349. Epub 2012 Nov 3.

16.

High-anxious individuals show increased chronic stress burden, decreased protective immunity, and increased cancer progression in a mouse model of squamous cell carcinoma.

Dhabhar FS, Saul AN, Holmes TH, Daugherty C, Neri E, Tillie JM, Kusewitt D, Oberyszyn TM.

PLoS One. 2012;7(4):e33069. doi: 10.1371/journal.pone.0033069. Epub 2012 Apr 25.

17.

UV light B-mediated inhibition of skin catalase activity promotes Gr-1+ CD11b+ myeloid cell expansion.

Sullivan NJ, Tober KL, Burns EM, Schick JS, Riggenbach JA, Mace TA, Bill MA, Young GS, Oberyszyn TM, Lesinski GB.

J Invest Dermatol. 2012 Mar;132(3 Pt 1):695-702. doi: 10.1038/jid.2011.329. Epub 2011 Oct 27.

18.

Short-term stress enhances cellular immunity and increases early resistance to squamous cell carcinoma.

Dhabhar FS, Saul AN, Daugherty C, Holmes TH, Bouley DM, Oberyszyn TM.

Brain Behav Immun. 2010 Jan;24(1):127-37. doi: 10.1016/j.bbi.2009.09.004. Epub 2009 Sep 16.

19.

Celecoxib reduces the effects of acute and chronic UVB exposure in mice treated with therapeutically relevant immunosuppressive drugs.

Wulff BC, Thomas-Ahner JM, Schick JS, Oberyszyn TM.

Int J Cancer. 2010 Jan 1;126(1):11-8. doi: 10.1002/ijc.24749.

20.

Topical treatment with black raspberry extract reduces cutaneous UVB-induced carcinogenesis and inflammation.

Duncan FJ, Martin JR, Wulff BC, Stoner GD, Tober KL, Oberyszyn TM, Kusewitt DF, Van Buskirk AM.

Cancer Prev Res (Phila). 2009 Jul;2(7):665-72. doi: 10.1158/1940-6207.CAPR-08-0193.

21.

Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells.

Sullivan NJ, Sasser AK, Axel AE, Vesuna F, Raman V, Ramirez N, Oberyszyn TM, Hall BM.

Oncogene. 2009 Aug 20;28(33):2940-7. doi: 10.1038/onc.2009.180. Epub 2009 Jul 6.

22.

Chromosomal aberrations in UVB-induced tumors of immunosuppressed mice.

Dworkin AM, Tober KL, Duncan FJ, Yu L, VanBuskirk AM, Oberyszyn TM, Toland AE.

Genes Chromosomes Cancer. 2009 Jun;48(6):490-501. doi: 10.1002/gcc.20657.

23.

Macrophage migration inhibitory factor (MIF) plays a critical role in pathogenesis of ultraviolet-B (UVB) -induced nonmelanoma skin cancer (NMSC).

Martin J, Duncan FJ, Keiser T, Shin S, Kusewitt DF, Oberyszyn T, Satoskar AR, VanBuskirk AM.

FASEB J. 2009 Mar;23(3):720-30. doi: 10.1096/fj.08-119628. Epub 2008 Oct 24.

PMID:
18952710
24.

The hairless mouse in skin research.

Benavides F, Oberyszyn TM, VanBuskirk AM, Reeve VE, Kusewitt DF.

J Dermatol Sci. 2009 Jan;53(1):10-8. doi: 10.1016/j.jdermsci.2008.08.012. Epub 2008 Oct 19. Review.

25.

Sirolimus reduces the incidence and progression of UVB-induced skin cancer in SKH mice even with co-administration of cyclosporine A.

Wulff BC, Kusewitt DF, VanBuskirk AM, Thomas-Ahner JM, Duncan FJ, Oberyszyn TM.

J Invest Dermatol. 2008 Oct;128(10):2467-73. doi: 10.1038/jid.2008.121. Epub 2008 May 8.

26.

Regulation of scar formation by vascular endothelial growth factor.

Wilgus TA, Ferreira AM, Oberyszyn TM, Bergdall VK, Dipietro LA.

Lab Invest. 2008 Jun;88(6):579-90. doi: 10.1038/labinvest.2008.36. Epub 2008 Apr 21.

27.

Beta 2-microglobulin deficient mice catabolize IgG more rapidly than FcRn- alpha-chain deficient mice.

Kim J, Bronson CL, Wani MA, Oberyszyn TM, Mohanty S, Chaudhury C, Hayton WL, Robinson JM, Anderson CL.

Exp Biol Med (Maywood). 2008 May;233(5):603-9. doi: 10.3181/0710-RM-270. Epub 2008 Mar 28.

PMID:
18375831
28.

Non-melanoma skin cancer: importance of gender, immunosuppressive status and vitamin D.

Oberyszyn TM.

Cancer Lett. 2008 Mar 18;261(2):127-36. doi: 10.1016/j.canlet.2008.01.009. Epub 2008 Feb 11. Review.

PMID:
18267352
29.

Hmga1 null mice are less susceptible to chemically induced skin carcinogenesis.

Visone R, Iuliano R, Palmieri D, Server IN, Chiappetta G, De Martino I, Fedele M, Costinean S, Oberyszyn TM, Kusewitt DF, Croce CM, Fusco A.

Eur J Cancer. 2008 Jan;44(2):318-25. Epub 2007 Dec 26.

PMID:
18155899
30.

Topical treatment with OGG1 enzyme affects UVB-induced skin carcinogenesis.

Wulff BC, Schick JS, Thomas-Ahner JM, Kusewitt DF, Yarosh DB, Oberyszyn TM.

Photochem Photobiol. 2008 Mar-Apr;84(2):317-21. Epub 2007 Dec 17.

PMID:
18086242
31.

Clinically relevant immunosuppressants influence UVB-induced tumor size through effects on inflammation and angiogenesis.

Duncan FJ, Wulff BC, Tober KL, Ferketich AK, Martin J, Thomas-Ahner JM, Allen SD, Kusewitt DF, Oberyszyn TM, Vanbuskirk AM.

Am J Transplant. 2007 Dec;7(12):2693-703. Epub 2007 Oct 17.

32.

Possible cross-regulation of the E prostanoid receptors.

Tober KL, Thomas-Ahner JM, Maruyama T, Oberyszyn TM.

Mol Carcinog. 2007 Aug;46(8):711-5. Review.

PMID:
17538953
33.

Inflammation and wound healing.

Oberyszyn TM.

Front Biosci. 2007 May 1;12:2993-9. Review.

PMID:
17485276
34.

Gender differences in UVB-induced skin carcinogenesis, inflammation, and DNA damage.

Thomas-Ahner JM, Wulff BC, Tober KL, Kusewitt DF, Riggenbach JA, Oberyszyn TM.

Cancer Res. 2007 Apr 1;67(7):3468-74. Epub 2007 Mar 27.

35.

Depletion of CD4+ cells exacerbates the cutaneous response to acute and chronic UVB exposure.

Hatton JL, Parent A, Tober KL, Hoppes T, Wulff BC, Duncan FJ, Kusewitt DF, VanBuskirk AM, Oberyszyn TM.

J Invest Dermatol. 2007 Jun;127(6):1507-15. Epub 2007 Mar 15.

36.

Accelerated transferrin degradation in HFE-deficient mice is associated with increased transferrin saturation.

Chaudhury C, Kim J, Mehnaz S, Wani MA, Oberyszyn TM, Bronson CL, Mohanty S, Hayton WL, Robinson JM, Anderson CL.

J Nutr. 2006 Dec;136(12):2993-8.

PMID:
17116709
37.

Effects of UVB on E prostanoid receptor expression in murine skin.

Tober KL, Thomas-Ahner JM, Kusewitt DF, Oberyszyn TM.

J Invest Dermatol. 2007 Jan;127(1):214-21. Epub 2006 Aug 17.

38.

Importance of the EP(1) receptor in cutaneous UVB-induced inflammation and tumor development.

Tober KL, Wilgus TA, Kusewitt DF, Thomas-Ahner JM, Maruyama T, Oberyszyn TM.

J Invest Dermatol. 2006 Jan;126(1):205-11.

39.

Chronic stress and susceptibility to skin cancer.

Saul AN, Oberyszyn TM, Daugherty C, Kusewitt D, Jones S, Jewell S, Malarkey WB, Lehman A, Lemeshow S, Dhabhar FS.

J Natl Cancer Inst. 2005 Dec 7;97(23):1760-7.

40.

Hydrogen peroxide disrupts scarless fetal wound repair.

Wilgus TA, Bergdall VK, Dipietro LA, Oberyszyn TM.

Wound Repair Regen. 2005 Sep-Oct;13(5):513-9.

PMID:
16176460
41.
42.

The impact of cyclooxygenase-2 mediated inflammation on scarless fetal wound healing.

Wilgus TA, Bergdall VK, Tober KL, Hill KJ, Mitra S, Flavahan NA, Oberyszyn TM.

Am J Pathol. 2004 Sep;165(3):753-61.

43.

Treatment with 5-fluorouracil and celecoxib displays synergistic regression of ultraviolet light B-induced skin tumors.

Wilgus TA, Breza TS Jr, Tober KL, Oberyszyn TM.

J Invest Dermatol. 2004 Jun;122(6):1488-94.

44.

Inhibition of cutaneous ultraviolet light B-mediated inflammation and tumor formation with topical celecoxib treatment.

Wilgus TA, Koki AT, Zweifel BS, Kusewitt DF, Rubal PA, Oberyszyn TM.

Mol Carcinog. 2003 Oct;38(2):49-58.

PMID:
14502644
45.

Chemotherapeutic efficacy of topical celecoxib in a murine model of ultraviolet light B-induced skin cancer.

Wilgus TA, Koki AT, Zweifel BS, Rubal PA, Oberyszyn TM.

Mol Carcinog. 2003 Sep;38(1):33-9.

PMID:
12949841
46.

Inhibition of ultraviolet light B-induced cutaneous inflammation by a specific cyclooxygenase-2 inhibitor.

Wilgus TA, Parrett ML, Ross MS, Tober KL, Robertson FM, Oberyszyn TM.

Adv Exp Med Biol. 2002;507:85-92.

PMID:
12664569
47.

Reduction of scar formation in full-thickness wounds with topical celecoxib treatment.

Wilgus TA, Vodovotz Y, Vittadini E, Clubbs EA, Oberyszyn TM.

Wound Repair Regen. 2003 Jan-Feb;11(1):25-34.

PMID:
12581424
48.

Protection of human keratinocyte mtDNA by low-level nitric oxide.

Shokolenko I, Oberyszyn TM, D'Ambrosio SM, Saavedra JE, Keefer LK, LeDoux SP, Wilson GL, Robertson FM.

Nitric Oxide. 2001 Dec;5(6):555-60.

PMID:
11730362
49.

Inhibition of cutaneous UV light-induced tumor necrosis factor-alpha protein production by Allotrap 1258, a novel immunomodulatory peptide.

Oberyszyn TM, Robertson FM, Tober KL, Ross MS, Parrett ML, Wilgus TA, Iyer S, Woo J, Buelow R.

Photochem Photobiol. 2001 Feb;73(2):184-90.

PMID:
11272733
50.

Topical application of a selective cyclooxygenase inhibitor suppresses UVB mediated cutaneous inflammation.

Wilgus TA, Ross MS, Parrett ML, Oberyszyn TM.

Prostaglandins Other Lipid Mediat. 2000 Oct;62(4):367-84.

PMID:
11060900

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