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Items: 31


Host-Derived Leukotriene B4 Is Critical for Resistance against Invasive Pulmonary Aspergillosis.

Caffrey-Carr AK, Hilmer KM, Kowalski CH, Shepardson KM, Temple RM, Cramer RA, Obar JJ.

Front Immunol. 2018 Jan 11;8:1984. doi: 10.3389/fimmu.2017.01984. eCollection 2017.


Type III interferon is a critical regulator of innate antifungal immunity.

Espinosa V, Dutta O, McElrath C, Du P, Chang YJ, Cicciarelli B, Pitler A, Whitehead I, Obar JJ, Durbin JE, Kotenko SV, Rivera A.

Sci Immunol. 2017 Oct 6;2(16). pii: eaan5357. doi: 10.1126/sciimmunol.aan5357.


IL-1α is Critical for Resistance Against Highly Virulent Aspergillus fumigatus Isolates.

Caffrey-Carr AK, Kowalski CH, Beattie SR, Blaseg NA, Upshaw CR, Thammahong A, Lust HE, Tang YW, Hohl TM, Cramer RA, Obar JJ.

Infect Immun. 2017 Sep 25. pii: IAI.00661-17. doi: 10.1128/IAI.00661-17. [Epub ahead of print]


Aspergillus fumigatus Trehalose-Regulatory Subunit Homolog Moonlights To Mediate Cell Wall Homeostasis through Modulation of Chitin Synthase Activity.

Thammahong A, Caffrey-Card AK, Dhingra S, Obar JJ, Cramer RA.

MBio. 2017 Apr 25;8(2). pii: e00056-17. doi: 10.1128/mBio.00056-17.


Filamentous fungal carbon catabolite repression supports metabolic plasticity and stress responses essential for disease progression.

Beattie SR, Mark KMK, Thammahong A, Ries LNA, Dhingra S, Caffrey-Carr AK, Cheng C, Black CC, Bowyer P, Bromley MJ, Obar JJ, Goldman GH, Cramer RA.

PLoS Pathog. 2017 Apr 19;13(4):e1006340. doi: 10.1371/journal.ppat.1006340. eCollection 2017 Apr.


Heterogeneity among Isolates Reveals that Fitness in Low Oxygen Correlates with Aspergillus fumigatus Virulence.

Kowalski CH, Beattie SR, Fuller KK, McGurk EA, Tang YW, Hohl TM, Obar JJ, Cramer RA Jr.

MBio. 2016 Sep 20;7(5). pii: e01515-16. doi: 10.1128/mBio.01515-16.


Alarmin(g) the innate immune system to invasive fungal infections.

Caffrey AK, Obar JJ.

Curr Opin Microbiol. 2016 Aug;32:135-143. doi: 10.1016/j.mib.2016.06.002. Epub 2016 Jun 27. Review.


New advances in invasive aspergillosis immunobiology leading the way towards personalized therapeutic approaches.

Obar JJ, Hohl TM, Cramer RA.

Cytokine. 2016 Aug;84:63-73. doi: 10.1016/j.cyto.2016.05.015. Epub 2016 May 30. Review.


Editorial: Vγ9Vδ2 T cells: triple costimulation goes the distance.

Sheridan BS, Obar JJ.

J Leukoc Biol. 2016 Apr;99(4):515-7. doi: 10.1189/jlb.1CE1115-522R. No abstract available.


Early Effector CD8 T Cells Display Plasticity in Populating the Short-Lived Effector and Memory-Precursor Pools Following Bacterial or Viral Infection.

Plumlee CR, Obar JJ, Colpitts SL, Jellison ER, Haining WN, Lefrancois L, Khanna KM.

Sci Rep. 2015 Jul 20;5:12264. doi: 10.1038/srep12264.


Mast cells and influenza a virus: association with allergic responses and beyond.

Graham AC, Temple RM, Obar JJ.

Front Immunol. 2015 May 18;6:238. doi: 10.3389/fimmu.2015.00238. eCollection 2015. Review.


IL-1α signaling is critical for leukocyte recruitment after pulmonary Aspergillus fumigatus challenge.

Caffrey AK, Lehmann MM, Zickovich JM, Espinosa V, Shepardson KM, Watschke CP, Hilmer KM, Thammahong A, Barker BM, Rivera A, Cramer RA, Obar JJ.

PLoS Pathog. 2015 Jan 28;11(1):e1004625. doi: 10.1371/journal.ppat.1004625. eCollection 2015 Jan.


Myeloid derived hypoxia inducible factor 1-alpha is required for protection against pulmonary Aspergillus fumigatus infection.

Shepardson KM, Jhingran A, Caffrey A, Obar JJ, Suratt BT, Berwin BL, Hohl TM, Cramer RA.

PLoS Pathog. 2014 Sep 25;10(9):e1004378. doi: 10.1371/journal.ppat.1004378. eCollection 2014 Sep.


Agonistic anti-CD40 enhances the CD8+ T cell response during vesicular stomatitis virus infection.

Zickovich JM, Meyer SI, Yagita H, Obar JJ.

PLoS One. 2014 Aug 28;9(8):e106060. doi: 10.1371/journal.pone.0106060. eCollection 2014.


Tracking cytotoxic potential in vivo.

Obar JJ, Sheridan BS.

Cell Mol Immunol. 2015 Jul;12(4):505-7. doi: 10.1038/cmi.2014.69. Epub 2014 Jul 28. Review. No abstract available.


Inflammatory response of mast cells during influenza A virus infection is mediated by active infection and RIG-I signaling.

Graham AC, Hilmer KM, Zickovich JM, Obar JJ.

J Immunol. 2013 May 1;190(9):4676-84. doi: 10.4049/jimmunol.1202096. Epub 2013 Mar 22.


A potential new pathway for PD-L1 costimulation of the CD8-T cell response to Listeria monocytogenes infection.

Xu D, Fu HH, Obar JJ, Park JJ, Tamada K, Yagita H, Lefrançois L.

PLoS One. 2013;8(2):e56539. doi: 10.1371/journal.pone.0056539. Epub 2013 Feb 11.


Cutting edge: the role of IFN-α receptor and MyD88 signaling in induction of IL-15 expression in vivo.

Colpitts SL, Stoklasek TA, Plumlee CR, Obar JJ, Guo C, Lefrançois L.

J Immunol. 2012 Mar 15;188(6):2483-7. doi: 10.4049/jimmunol.1103609. Epub 2012 Feb 10.


Pathogen-induced inflammatory environment controls effector and memory CD8+ T cell differentiation.

Obar JJ, Jellison ER, Sheridan BS, Blair DA, Pham QM, Zickovich JM, Lefrançois L.

J Immunol. 2011 Nov 15;187(10):4967-78. doi: 10.4049/jimmunol.1102335. Epub 2011 Oct 10.


Once a killer, always a killer: from cytotoxic T cell to memory cell.

Lefrançois L, Obar JJ.

Immunol Rev. 2010 May;235(1):206-18. doi: 10.1111/j.0105-2896.2010.00895.x. Review.


Early signals during CD8 T cell priming regulate the generation of central memory cells.

Obar JJ, Lefrançois L.

J Immunol. 2010 Jul 1;185(1):263-72. doi: 10.4049/jimmunol.1000492. Epub 2010 Jun 2.


Early events governing memory CD8+ T-cell differentiation.

Obar JJ, Lefrançois L.

Int Immunol. 2010 Aug;22(8):619-25. doi: 10.1093/intimm/dxq053. Epub 2010 May 26. Review.


Memory CD8+ T cell differentiation.

Obar JJ, Lefrançois L.

Ann N Y Acad Sci. 2010 Jan;1183:251-66. doi: 10.1111/j.1749-6632.2009.05126.x. Review.


CD4+ T cell regulation of CD25 expression controls development of short-lived effector CD8+ T cells in primary and secondary responses.

Obar JJ, Molloy MJ, Jellison ER, Stoklasek TA, Zhang W, Usherwood EJ, Lefrançois L.

Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):193-8. doi: 10.1073/pnas.0909945107. Epub 2009 Dec 4.


Endogenous naive CD8+ T cell precursor frequency regulates primary and memory responses to infection.

Obar JJ, Khanna KM, Lefrançois L.

Immunity. 2008 Jun;28(6):859-69. doi: 10.1016/j.immuni.2008.04.010. Epub 2008 May 22.


CD80 and CD86 control antiviral CD8+ T-cell function and immune surveillance of murine gammaherpesvirus 68.

Fuse S, Obar JJ, Bellfy S, Leung EK, Zhang W, Usherwood EJ.

J Virol. 2006 Sep;80(18):9159-70.


Gammaherpesvirus persistence alters key CD8 T-cell memory characteristics and enhances antiviral protection.

Obar JJ, Fuse S, Leung EK, Bellfy SC, Usherwood EJ.

J Virol. 2006 Sep;80(17):8303-15.


IL-15-independent proliferative renewal of memory CD8+ T cells in latent gammaherpesvirus infection.

Obar JJ, Crist SG, Leung EK, Usherwood EJ.

J Immunol. 2004 Aug 15;173(4):2705-14.


Quantitative analysis of LP-BM5 murine leukemia retrovirus RNA using real-time RT-PCR.

Cook WJ, Green KA, Obar JJ, Green WR.

J Virol Methods. 2003 Mar;108(1):49-58.


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