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Items: 1 to 50 of 577

1.

Lesion Index-Guided Ablation Facilitates Continuous, Transmural, and Durable Lesions in a Porcine Recovery Model.

Whitaker J, Fish J, Harrison J, Chubb H, Williams SE, Fastl T, Corrado C, Van Zaen J, Gibbs J, O'Neill L, Mukherjee R, Rittey D, Thorsten J, Donskoy E, Sohal M, Rajani R, Niederer S, Wright M, O'Neill MD.

Circ Arrhythm Electrophysiol. 2018 Apr;11(4):e005892. doi: 10.1161/CIRCEP.117.005892.

PMID:
29654131
2.

Loss of microRNA-21 Influences the Gut Microbiota Causing Reduced Susceptibility in a Murine Model of Colitis.

Johnston DGW, Williams MA, Thaiss CA, Cabrera-Rubio R, Raverdeau M, McEntee C, Cotter PD, Elinav E, O'Neill LAJ, Corr SC.

J Crohns Colitis. 2018 Mar 28. doi: 10.1093/ecco-jcc/jjy038. [Epub ahead of print]

PMID:
29608690
3.

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.

Mills EL, Ryan DG, Prag HA, Dikovskaya D, Menon D, Zaslona Z, Jedrychowski MP, Costa ASH, Higgins M, Hams E, Szpyt J, Runtsch MC, King MS, McGouran JF, Fischer R, Kessler BM, McGettrick AF, Hughes MM, Carroll RG, Booty LM, Knatko EV, Meakin PJ, Ashford MLJ, Modis LK, Brunori G, Sévin DC, Fallon PG, Caldwell ST, Kunji ERS, Chouchani ET, Frezza C, Dinkova-Kostova AT, Hartley RC, Murphy MP, O'Neill LA.

Nature. 2018 Apr 5;556(7699):113-117. doi: 10.1038/nature25986. Epub 2018 Mar 28.

PMID:
29590092
4.

Reply to Tagliabue.

Pearce W, Hartley S, Helliwell R, O'Neill L.

EMBO Rep. 2018 Apr;19(4). pii: e45954. doi: 10.15252/embr.201845954. Epub 2018 Mar 7. No abstract available.

PMID:
29514864
5.

Macrophages Remember Cheeseburgers and Promote Inflammation via NLRP3.

O'Neill LAJ, Zaslona Z.

Trends Mol Med. 2018 Apr;24(4):335-337. doi: 10.1016/j.molmed.2018.02.005. Epub 2018 Feb 23.

PMID:
29483038
6.

Evidence against a role for NLRP3-driven islet inflammation in db/db mice.

Kammoun HL, Allen TL, Henstridge DC, Barre S, Coll RC, Lancaster GI, Cron L, Reibe S, Chan JY, Bensellam M, Laybutt DR, Butler MS, Robertson AAB, O'Neill LA, Cooper MA, Febbraio MA.

Mol Metab. 2018 Apr;10:66-73. doi: 10.1016/j.molmet.2018.02.001. Epub 2018 Feb 7.

7.

An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation.

Carroll RG, Zasłona Z, Galván-Peña S, Koppe EL, Sévin DC, Angiari S, Triantafilou M, Triantafilou K, Modis LK, O'Neill LA.

J Biol Chem. 2018 Apr 13;293(15):5509-5521. doi: 10.1074/jbc.RA118.001921. Epub 2018 Feb 20.

8.

A Role for the Krebs Cycle Intermediate Citrate in Metabolic Reprogramming in Innate Immunity and Inflammation.

Williams NC, O'Neill LAJ.

Front Immunol. 2018 Feb 5;9:141. doi: 10.3389/fimmu.2018.00141. eCollection 2018. Review.

9.

Patient experiences of a physiotherapy-led multidisciplinary rehabilitative intervention after successful treatment for oesophago-gastric cancer.

Bennett AE, O'Neill L, Connolly D, Guinan EM, Boland L, Doyle SL, O'Sullivan J, Reynolds JV, Hussey J.

Support Care Cancer. 2018 Feb 18. doi: 10.1007/s00520-018-4112-6. [Epub ahead of print]

PMID:
29455302
10.

Synthesis, characterisation and DNA intercalation studies of regioisomers of ruthenium (II) polypyridyl complexes.

Perdisatt L, Moqadasi S, O'Neill L, Hessman G, Ghion A, Warraich MQM, Casey A, O'Connor C.

J Inorg Biochem. 2018 May;182:71-82. doi: 10.1016/j.jinorgbio.2018.01.018. Epub 2018 Feb 9.

PMID:
29452882
11.

Canakinumab for Atherosclerotic Disease.

O'Neill LA, Cooper MA.

N Engl J Med. 2018 Jan 11;378(2):198-9. doi: 10.1056/NEJMc1714635. No abstract available.

PMID:
29322757
12.

Multidisciplinary rehabilitation across the esophageal cancer journey.

O'Neill L, Gannon J, Guinan E, Reynolds JV, Hussey J.

J Thorac Dis. 2017 Dec;9(12):E1140-E1142. doi: 10.21037/jtd.2017.11.72. No abstract available.

13.

Epicardial electroanatomical mapping, radiofrequency ablation, and lesion imaging in the porcine left ventricle under real-time magnetic resonance imaging guidance-an in vivo feasibility study.

Mukherjee RK, Roujol S, Chubb H, Harrison J, Williams S, Whitaker J, O'Neill L, Silberbauer J, Neji R, Schneider R, Pohl T, Lloyd T, O'Neill M, Razavi R.

Europace. 2017 Dec 26. doi: 10.1093/europace/eux341. [Epub ahead of print]

PMID:
29294008
14.

GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity.

Menon D, Innes A, Oakley AJ, Dahlstrom JE, Jensen LM, Brüstle A, Tummala P, Rooke M, Casarotto MG, Baell JB, Nguyen N, Xie Y, Cuellar M, Strasser J, Dahlin JL, Walters MA, Burgio G, O'Neill LAJ, Board PG.

Sci Rep. 2017 Dec 19;7(1):17832. doi: 10.1038/s41598-017-17861-6.

15.

Metabolic regulation of NLRP3.

Hughes MM, O'Neill LAJ.

Immunol Rev. 2018 Jan;281(1):88-98. doi: 10.1111/imr.12608. Review.

PMID:
29247992
16.

Loss of the molecular clock in myeloid cells exacerbates T cell-mediated CNS autoimmune disease.

Sutton CE, Finlay CM, Raverdeau M, Early JO, DeCourcey J, Zaslona Z, O'Neill LAJ, Mills KHG, Curtis AM.

Nat Commun. 2017 Dec 12;8(1):1923. doi: 10.1038/s41467-017-02111-0.

17.

Sarcopenia during neoadjuvant therapy for oesophageal cancer: characterising the impact on muscle strength and physical performance.

Guinan EM, Doyle SL, Bennett AE, O'Neill L, Gannon J, Elliott JA, O'Sullivan J, Reynolds JV, Hussey J.

Support Care Cancer. 2018 May;26(5):1569-1576. doi: 10.1007/s00520-017-3993-0. Epub 2017 Dec 2.

PMID:
29197960
18.

Efficacy of a Micro-Prompting Technology in Reducing Support Needed by People With Severe Acquired Brain Injury in Activities of Daily Living: A Randomized Control Trial.

OʼNeill B, Best C, OʼNeill L, Ramos SDS, Gillespie A.

J Head Trauma Rehabil. 2017 Nov 29. doi: 10.1097/HTR.0000000000000358. [Epub ahead of print]

PMID:
29194177
19.

GOTcha: lncRNA-ACOD1 targets metabolism during viral infection.

Runtsch MC, O'Neill LA.

Cell Res. 2018 Feb;28(2):137-138. doi: 10.1038/cr.2017.153. Epub 2017 Dec 1.

PMID:
29192676
20.

Why are NGOs sceptical of genome editing? NGOs' opposition to agricultural biotechnologies is rooted in scepticism about the framing of problems and solutions, rather than just emotion and dogma.

Helliwell R, Hartley S, Pearce W, O'Neill L.

EMBO Rep. 2017 Dec;18(12):2090-2093. doi: 10.15252/embr.201744385. Epub 2017 Nov 2. No abstract available.

PMID:
29097395
21.

Pyruvate Kinase M2 Is Required for the Expression of the Immune Checkpoint PD-L1 in Immune Cells and Tumors.

Palsson-McDermott EM, Dyck L, Zasłona Z, Menon D, McGettrick AF, Mills KHG, O'Neill LA.

Front Immunol. 2017 Oct 13;8:1300. doi: 10.3389/fimmu.2017.01300. eCollection 2017.

22.

Acceptability of the Fitbit in behavioural activation therapy for depression: a qualitative study.

Chum J, Kim MS, Zielinski L, Bhatt M, Chung D, Yeung S, Litke K, McCabe K, Whattam J, Garrick L, O'Neill L, Goyert S, Merrifield C, Patel Y, Samaan Z.

Evid Based Ment Health. 2017 Nov;20(4):128-133. doi: 10.1136/eb-2017-102763. Epub 2017 Oct 22.

23.

Long-lived tissue resident HIV-1 specific memory CD8+ T cells are generated by skin immunization with live virus vectored microneedle arrays.

Zaric M, Becker PD, Hervouet C, Kalcheva P, Ibarzo Yus B, Cocita C, O'Neill LA, Kwon SY, Klavinskis LS.

J Control Release. 2017 Dec 28;268:166-175. doi: 10.1016/j.jconrel.2017.10.026. Epub 2017 Oct 19.

24.

Prophylactic Catheter Ablation for Ventricular Tachycardia: Are We There Yet?

Mukherjee RK, O'Neill L, O'Neill MD.

Arrhythm Electrophysiol Rev. 2017 Aug;6(3):125-128. doi: 10.15420/aer.2017:17:1.

25.

Qualitative analysis of MMI raters' scorings of medical school candidates: A matter of taste?

Christensen MK, Lykkegaard E, Lund O, O'Neill LD.

Adv Health Sci Educ Theory Pract. 2018 May;23(2):289-310. doi: 10.1007/s10459-017-9794-x. Epub 2017 Sep 27.

PMID:
28956195
26.

Are parrots poor at motor self-regulation or is the cylinder task poor at measuring it?

Kabadayi C, Krasheninnikova A, O'Neill L, van de Weijer J, Osvath M, von Bayern AMP.

Anim Cogn. 2017 Nov;20(6):1137-1146. doi: 10.1007/s10071-017-1131-5. Epub 2017 Sep 19.

27.

MyD88 is an essential component of retinoic acid-induced differentiation in human pluripotent embryonal carcinoma cells.

Sulaiman G, Cooke A, Ffrench B, Gasch C, Abdullai OA, O'Connor K, Elbaruni S, Blackshields G, Spillane C, Keegan H, McEneaney V, Knittel R, Rogers A, Jeffery IB, Doyle B, Bates M, d'Adhemar C, Lee MY, Campbell EL, Moynagh PN, Higgins DG, O'Toole S, O'Neill L, O'Leary JJ, Gallagher MF.

Cell Death Differ. 2017 Nov;24(11):1975-1986. doi: 10.1038/cdd.2017.124. Epub 2017 Sep 8.

PMID:
28885616
28.

Specific inhibition of NLRP3 in chikungunya disease reveals a role for inflammasomes in alphavirus-induced inflammation.

Chen W, Foo SS, Zaid A, Teng TS, Herrero LJ, Wolf S, Tharmarajah K, Vu LD, van Vreden C, Taylor A, Freitas JR, Li RW, Woodruff TM, Gordon R, Ojcius DM, Nakaya HI, Kanneganti TD, O'Neill LAJ, Robertson AAB, King NJ, Suhrbier A, Cooper MA, Ng LFP, Mahalingam S.

Nat Microbiol. 2017 Oct;2(10):1435-1445. doi: 10.1038/s41564-017-0015-4. Epub 2017 Aug 28.

PMID:
28848230
29.

Evaluating and Extending the Ocean Wind Climate Data Record.

Wentz FJ, Ricciardulli L, Rodriguez E, Stiles BW, Bourassa MA, Long DG, Hoffman RN, Stoffelen A, Verhoef A, O'Neill LW, Farrar JT, Vandemark D, Fore AG, Hristova-Veleva SM, Turk FJ, Gaston R, Tyler D.

IEEE J Sel Top Appl Earth Obs Remote Sens. 2017 May;10(5):2165-2185. doi: 10.1109/JSTARS.2016.2643641. Epub 2017 May 23.

30.

Discharges with surgical procedures performed less often than once per month per hospital account for two-thirds of hospital costs of inpatient surgery.

O'Neill L, Dexter F, Park SH, Epstein RH.

J Clin Anesth. 2017 Sep;41:99-103. doi: 10.1016/j.jclinane.2017.07.003. Epub 2017 Jul 21.

PMID:
28802622
31.

Uncommon combinations of ICD10-PCS or ICD-9-CM operative procedure codes account for most inpatient surgery at half of Texas hospitals.

O'Neill L, Dexter F, Park SH, Epstein RH.

J Clin Anesth. 2017 Sep;41:65-70. doi: 10.1016/j.jclinane.2017.06.002. Epub 2017 Jun 30.

PMID:
28802614
32.

Suspected Pediatric Influenza Risk-Stratification Algorithm: A Clinical Decision Tool.

Evers PD, Starr M, McNeil MJ, OʼNeill L, Posa A, Savage T, Migita R.

Pediatr Emerg Care. 2017 Aug 1. doi: 10.1097/PEC.0000000000001243. [Epub ahead of print]

PMID:
28763405
33.

Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling.

Hughes MM, Lavrencic P, Coll RC, Ve T, Ryan DG, Williams NC, Menon D, Mansell A, Board PG, Mobli M, Kobe B, O'Neill LAJ.

Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):E6480-E6489. doi: 10.1073/pnas.1701868114. Epub 2017 Jul 24.

34.

A guiding map for inflammation.

Netea MG, Balkwill F, Chonchol M, Cominelli F, Donath MY, Giamarellos-Bourboulis EJ, Golenbock D, Gresnigt MS, Heneka MT, Hoffman HM, Hotchkiss R, Joosten LAB, Kastner DL, Korte M, Latz E, Libby P, Mandrup-Poulsen T, Mantovani A, Mills KHG, Nowak KL, O'Neill LA, Pickkers P, van der Poll T, Ridker PM, Schalkwijk J, Schwartz DA, Siegmund B, Steer CJ, Tilg H, van der Meer JWM, van de Veerdonk FL, Dinarello CA.

Nat Immunol. 2017 Jul 19;18(8):826-831. doi: 10.1038/ni.3790.

PMID:
28722720
35.

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy.

To EE, Vlahos R, Luong R, Halls ML, Reading PC, King PT, Chan C, Drummond GR, Sobey CG, Broughton BRS, Starkey MR, van der Sluis R, Lewin SR, Bozinovski S, O'Neill LAJ, Quach T, Porter CJH, Brooks DA, O'Leary JJ, Selemidis S.

Nat Commun. 2017 Jul 12;8(1):69. doi: 10.1038/s41467-017-00057-x.

36.

Response to letter: 'Bear tracks hypothesis: from atrial fibrillation to atrial fibrosis syndrome in stroke risk assessment'.

O'Neill L, Harrison J, O'Neill M, Williams SE.

Expert Rev Cardiovasc Ther. 2017 Aug;15(8):563. doi: 10.1080/14779072.2017.1355240. Epub 2017 Jul 14. No abstract available.

PMID:
28699363
37.

Krebs cycle rewired for macrophage and dendritic cell effector functions.

Ryan DG, O'Neill LAJ.

FEBS Lett. 2017 Oct;591(19):2992-3006. doi: 10.1002/1873-3468.12744. Epub 2017 Jul 26. Review.

PMID:
28685841
38.

The effect of activation rate on left atrial bipolar voltage in patients with paroxysmal atrial fibrillation.

Williams SE, Linton N, O'Neill L, Harrison J, Whitaker J, Mukherjee R, Rinaldi CA, Gill J, Niederer S, Wright M, O'Neill M.

J Cardiovasc Electrophysiol. 2017 Sep;28(9):1028-1036. doi: 10.1111/jce.13282.

39.

MicroRNA-21 Limits Uptake of Listeria monocytogenes by Macrophages to Reduce the Intracellular Niche and Control Infection.

Johnston DGW, Kearney J, Zasłona Z, Williams MA, O'Neill LAJ, Corr SC.

Front Cell Infect Microbiol. 2017 May 23;7:201. doi: 10.3389/fcimb.2017.00201. eCollection 2017.

40.

The intracellular chloride channel proteins CLIC1 and CLIC4 induce IL-1β transcription and activate the NLRP3 inflammasome.

Domingo-Fernández R, Coll RC, Kearney J, Breit S, O'Neill LAJ.

J Biol Chem. 2017 Jul 21;292(29):12077-12087. doi: 10.1074/jbc.M117.797126. Epub 2017 Jun 2.

PMID:
28576828
41.

A pilot mobile integrated healthcare program for frequent utilizers of emergency department services.

Nejtek VA, Aryal S, Talari D, Wang H, O'Neill L.

Am J Emerg Med. 2017 Nov;35(11):1702-1705. doi: 10.1016/j.ajem.2017.04.061. Epub 2017 Apr 27.

PMID:
28495031
42.

Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome.

Neudecker V, Haneklaus M, Jensen O, Khailova L, Masterson JC, Tye H, Biette K, Jedlicka P, Brodsky KS, Gerich ME, Mack M, Robertson AAB, Cooper MA, Furuta GT, Dinarello CA, O'Neill LA, Eltzschig HK, Masters SL, McNamee EN.

J Exp Med. 2017 Jun 5;214(6):1737-1752. doi: 10.1084/jem.20160462. Epub 2017 May 9.

43.

Mitochondria are the powerhouses of immunity.

Mills EL, Kelly B, O'Neill LAJ.

Nat Immunol. 2017 Apr 18;18(5):488-498. doi: 10.1038/ni.3704. Review.

PMID:
28418387
44.

Macrophage Immunometabolism: Where Are We (Going)?

Van den Bossche J, O'Neill LA, Menon D.

Trends Immunol. 2017 Jun;38(6):395-406. doi: 10.1016/j.it.2017.03.001. Epub 2017 Apr 7. Review.

PMID:
28396078
45.

The circadian protein BMAL1 in myeloid cells is a negative regulator of allergic asthma.

Zasłona Z, Case S, Early JO, Lalor SJ, McLoughlin RM, Curtis AM, O'Neill LAJ.

Am J Physiol Lung Cell Mol Physiol. 2017 Jun 1;312(6):L855-L860. doi: 10.1152/ajplung.00072.2017. Epub 2017 Mar 23.

PMID:
28336811
46.

The RNA-binding protein Tristetraprolin (TTP) is a critical negative regulator of the NLRP3 inflammasome.

Haneklaus M, O'Neil JD, Clark AR, Masters SL, O'Neill LAJ.

J Biol Chem. 2017 Apr 28;292(17):6869-6881. doi: 10.1074/jbc.M116.772947. Epub 2017 Mar 16.

PMID:
28302726
47.

Combined Electric and Acoustic Stimulation With Hearing Preservation: Effect of Cochlear Implant Low-Frequency Cutoff on Speech Understanding and Perceived Listening Difficulty.

Gifford RH, Davis TJ, Sunderhaus LW, Menapace C, Buck B, Crosson J, O'Neill L, Beiter A, Segel P.

Ear Hear. 2017 Sep/Oct;38(5):539-553. doi: 10.1097/AUD.0000000000000418.

PMID:
28301392
48.

The Induction of Pro-IL-1β by Lipopolysaccharide Requires Endogenous Prostaglandin E2 Production.

Zasłona Z, Pålsson-McDermott EM, Menon D, Haneklaus M, Flis E, Prendeville H, Corcoran SE, Peters-Golden M, O'Neill LAJ.

J Immunol. 2017 May 1;198(9):3558-3564. doi: 10.4049/jimmunol.1602072. Epub 2017 Mar 15.

PMID:
28298525
49.

Immunometabolism and the land of milk and honey.

O'Neill L.

Nat Rev Immunol. 2017 Apr;17(4):217. doi: 10.1038/nri.2017.22. Epub 2017 Mar 13. No abstract available.

PMID:
28287105
50.

Clinical, electrophysiological and imaging predictors of atrial fibrillation ablation outcome.

O'Neill L, Harrison J, O'Neill M, Williams SE.

Expert Rev Cardiovasc Ther. 2017 Apr;15(4):289-305. doi: 10.1080/14779072.2017.1303378. Epub 2017 Mar 17. Review.

PMID:
28267401

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