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Items: 1 to 50 of 302

1.

Post-Ugi Cascade Transformations for Accessing Diverse Chromenopyrrole Collections.

Srinivasulu V, Sieburth SM, El-Awady R, Kariem NM, Tarazi H, O'Connor MJ, Al-Tel TH.

Org Lett. 2018 Feb 2;20(3):836-839. doi: 10.1021/acs.orglett.7b03986. Epub 2018 Jan 12.

PMID:
29327591
2.

Characteristics and Outcomes of Pediatric Heart Failure-Related Emergency Department Visits in the United States: A Population-Based Study.

Mejia EJ, O'Connor MJ, Lin KY, Song L, Griffis H, Mascio CE, Shamszad P, Donoghue A, Ravishankar C, Shaddy RE, Rossano JW.

J Pediatr. 2018 Feb;193:114-118.e3. doi: 10.1016/j.jpeds.2017.10.009. Epub 2017 Dec 6.

PMID:
29221691
3.

The AGE-RAGE axis in an Arab population: The United Arab Emirates Healthy Futures (UAEHFS) pilot study.

Inman CK, Aljunaibi A, Koh H, Abdulle A, Ali R, Alnaeemi A, Al Zaabi E, Oumeziane N, Al Bastaki M, Al-Houqani M, Al-Maskari F, Al Dhaheri A, Shah SM, Abdel Wareth L, Al Mahmeed W, Alsafar H, Al Anouti F, Al Hosani A, Haji M, Galani D, O'Connor MJ, Ahn J, Kirchhoff T, Sherman S, Hayes RB, Li H, Ramasamy R, Schmidt AM.

J Clin Transl Endocrinol. 2017 Aug 14;10:1-8. doi: 10.1016/j.jcte.2017.08.001. eCollection 2017 Dec.

4.

Neoadjuvant olaparib targets hypoxia to improve radioresponse in a homologous recombination-proficient breast cancer model.

Borst GR, Kumareswaran R, Yücel H, Telli S, Do T, McKee T, Zafarana G, Jonkers J, Verheij M, O'Connor MJ, Rottenberg S, Bristow RG.

Oncotarget. 2017 Sep 15;8(50):87638-87646. doi: 10.18632/oncotarget.20936. eCollection 2017 Oct 20.

5.

PARP1 Trapping and DNA Replication Stress Enhance Radiosensitization with Combined WEE1 and PARP Inhibitors.

Parsels LA, Karnak D, Parsels JD, Zhang Q, Vélez-Padilla J, Reichert ZR, Wahl DR, Maybaum J, O'Connor MJ, Lawrence TS, Morgan MA.

Mol Cancer Res. 2018 Feb;16(2):222-232. doi: 10.1158/1541-7786.MCR-17-0455. Epub 2017 Nov 13.

PMID:
29133592
6.

ATR kinase inhibition induces unscheduled origin firing through a Cdc7-dependent association between GINS and And-1.

Moiseeva T, Hood B, Schamus S, O'Connor MJ, Conrads TP, Bakkenist CJ.

Nat Commun. 2017 Nov 9;8(1):1392. doi: 10.1038/s41467-017-01401-x.

7.

Modular Bi-Directional One-Pot Strategies for the Diastereoselective Synthesis of Structurally Diverse Collections of Constrained β-Carboline-Benzoxazepines.

Srinivasulu V, Mazitschek R, Kariem NM, Reddy A, Rabeh WM, Li L, O'Connor MJ, Al-Tel TH.

Chemistry. 2017 Oct 12;23(57):14182-14192. doi: 10.1002/chem.201702495. Epub 2017 Sep 7.

PMID:
28770556
8.

Value of a flow cytometry cross-match in the setting of a negative complement-dependent cytotoxicity cross-match in heart transplant recipients.

Keeshan BC, O'Connor MJ, Lin KY, Monos D, Lind C, Mascio CE, Rame JE, Spray TL, Shaddy RE, Rossano JW.

Clin Transplant. 2017 Oct;31(10). doi: 10.1111/ctr.13064. Epub 2017 Aug 30.

PMID:
28766759
9.

Development of quality metrics for ambulatory pediatric cardiology: Infection prevention.

Johnson JN, Barrett CS, Franklin WH, Graham EM, Halnon NJ, Hattendorf BA, Krawczeski CD, McGovern JJ, O'Connor MJ, Schultz AH, Vinocur JM, Chowdhury D, Anderson JB.

Congenit Heart Dis. 2017 Dec;12(6):756-761. doi: 10.1111/chd.12519. Epub 2017 Jul 25. Review.

PMID:
28741863
10.

Cannabinoid hyperemesis syndrome and topical capsaicin: treating smoke with fire? - the authors reply.

Hafez Z, Mullins ME, Blohm E, O'Connor MJ, Dezieck L, Schwarz ES, Conicella A.

Clin Toxicol (Phila). 2018 Jan;56(1):79. doi: 10.1080/15563650.2017.1349912. Epub 2017 Jul 21. No abstract available.

PMID:
28730852
11.

Multielectron Chemistry within a Model Nickel Metalloprotein: Mechanistic Implications for Acetyl-CoA Synthase.

Manesis AC, O'Connor MJ, Schneider CR, Shafaat HS.

J Am Chem Soc. 2017 Aug 2;139(30):10328-10338. doi: 10.1021/jacs.7b03892. Epub 2017 Jul 21.

PMID:
28675928
12.

The genome and phenome of the green alga Chloroidium sp. UTEX 3007 reveal adaptive traits for desert acclimatization.

Nelson DR, Khraiwesh B, Fu W, Alseekh S, Jaiswal A, Chaiboonchoe A, Hazzouri KM, O'Connor MJ, Butterfoss GL, Drou N, Rowe JD, Harb J, Fernie AR, Gunsalus KC, Salehi-Ashtiani K.

Elife. 2017 Jun 17;6. pii: e25783. doi: 10.7554/eLife.25783.

13.

Long-Term Outcomes of Pediatric Cardiac Patients Supported by Extracorporeal Membrane Oxygenation.

Elias MD, Achuff BJ, Ittenbach RF, Ravishankar C, Spray TL, Fuller S, Montenegro LM, Gaynor JW, O'Connor MJ.

Pediatr Crit Care Med. 2017 Aug;18(8):787-794. doi: 10.1097/PCC.0000000000001227.

PMID:
28598945
14.

NCBO Ontology Recommender 2.0: an enhanced approach for biomedical ontology recommendation.

Martínez-Romero M, Jonquet C, O'Connor MJ, Graybeal J, Pazos A, Musen MA.

J Biomed Semantics. 2017 Jun 7;8(1):21. doi: 10.1186/s13326-017-0128-y.

15.

Resolution of cannabis hyperemesis syndrome with topical capsaicin in the emergency department: a case series.

Dezieck L, Hafez Z, Conicella A, Blohm E, O'Connor MJ, Schwarz ES, Mullins ME.

Clin Toxicol (Phila). 2017 Sep;55(8):908-913. doi: 10.1080/15563650.2017.1324166. Epub 2017 May 11.

PMID:
28494183
16.

Emergency department utilization in pediatric heart transplant recipients.

Wittlieb-Weber CA, Rossano JW, Weber DR, Lin KY, Ravishankar C, Mascio CE, Shaddy RE, O'Connor MJ.

Pediatr Transplant. 2017 Jun;21(4). doi: 10.1111/petr.12936. Epub 2017 Apr 29.

PMID:
28455909
17.

In vitro amplification of H-type atypical bovine spongiform encephalopathy by protein misfolding cyclic amplification.

O'Connor MJ, Bishop K, Workman RG, Maddison BC, Gough KC.

Prion. 2017 Jan 2;11(1):54-64. doi: 10.1080/19336896.2016.1259051. Epub 2017 Feb 8.

18.

Long-Term Responders on Olaparib Maintenance in High-Grade Serous Ovarian Cancer: Clinical and Molecular Characterization.

Lheureux S, Lai Z, Dougherty BA, Runswick S, Hodgson DR, Timms KM, Lanchbury JS, Kaye S, Gourley C, Bowtell D, Kohn EC, Scott C, Matulonis U, Panzarella T, Karakasis K, Burnier JV, Gilks CB, O'Connor MJ, Robertson JD, Ledermann J, Barrett JC, Ho TW, Oza AM.

Clin Cancer Res. 2017 Aug 1;23(15):4086-4094. doi: 10.1158/1078-0432.CCR-16-2615. Epub 2017 Feb 21.

PMID:
28223274
19.

Pharmacologic ATM but not ATR kinase inhibition abrogates p21-dependent G1 arrest and promotes gastrointestinal syndrome after total body irradiation.

Vendetti FP, Leibowitz BJ, Barnes J, Schamus S, Kiesel BF, Abberbock S, Conrads T, Clump DA, Cadogan E, O'Connor MJ, Yu J, Beumer JH, Bakkenist CJ.

Sci Rep. 2017 Feb 1;7:41892. doi: 10.1038/srep41892.

20.

AZD6738, A Novel Oral Inhibitor of ATR, Induces Synthetic Lethality with ATM Deficiency in Gastric Cancer Cells.

Min A, Im SA, Jang H, Kim S, Lee M, Kim DK, Yang Y, Kim HJ, Lee KH, Kim JW, Kim TY, Oh DY, Brown J, Lau A, O'Connor MJ, Bang YJ.

Mol Cancer Ther. 2017 Apr;16(4):566-577. doi: 10.1158/1535-7163.MCT-16-0378. Epub 2017 Jan 30.

PMID:
28138034
21.

Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol.

Liu SL, Sheng R, Jung JH, Wang L, Stec E, O'Connor MJ, Song S, Bikkavilli RK, Winn RA, Lee D, Baek K, Ueda K, Levitan I, Kim KP, Cho W.

Nat Chem Biol. 2017 Mar;13(3):268-274. doi: 10.1038/nchembio.2268. Epub 2016 Dec 26.

PMID:
28024150
22.

Intramolecular Diaza-Diels-Alder Protocol: A New Diastereoselective and Modular One-Step Synthesis of Constrained Polycyclic Frameworks.

Srinivasulu V, Reddy A, Mazitschek R, Lukens AK, Wirth DF, Li L, Naumov P, O'Connor MJ, Al-Tel TH.

Chemistry. 2017 Mar 23;23(17):4137-4148. doi: 10.1002/chem.201605231. Epub 2017 Feb 17.

PMID:
27997727
23.

Prevalence and Risk Factors for Pericardial Effusions Requiring Readmission After Pediatric Cardiac Surgery.

Elias MD, Glatz AC, O'Connor MJ, Schachtner S, Ravishankar C, Mascio CE, Cohen MS.

Pediatr Cardiol. 2017 Mar;38(3):484-494. doi: 10.1007/s00246-016-1540-2. Epub 2016 Nov 30.

PMID:
27900408
24.

Laying a trap to kill cancer cells: PARP inhibitors and their mechanisms of action.

Pommier Y, O'Connor MJ, de Bono J.

Sci Transl Med. 2016 Oct 26;8(362):362ps17. Erratum in: Sci Transl Med. 2016 Dec 7;8(368):368er7.

PMID:
27797957
25.

Anti-tumor activity of the ATR inhibitor AZD6738 in HER2 positive breast cancer cells.

Kim HJ, Min A, Im SA, Jang H, Lee KH, Lau A, Lee M, Kim S, Yang Y, Kim J, Kim TY, Oh DY, Brown J, O'Connor MJ, Bang YJ.

Int J Cancer. 2017 Jan 1;140(1):109-119. doi: 10.1002/ijc.30373. Epub 2016 Oct 21.

26.

A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds.

Bruna A, Rueda OM, Greenwood W, Batra AS, Callari M, Batra RN, Pogrebniak K, Sandoval J, Cassidy JW, Tufegdzic-Vidakovic A, Sammut SJ, Jones L, Provenzano E, Baird R, Eirew P, Hadfield J, Eldridge M, McLaren-Douglas A, Barthorpe A, Lightfoot H, O'Connor MJ, Gray J, Cortes J, Baselga J, Marangoni E, Welm AL, Aparicio S, Serra V, Garnett MJ, Caldas C.

Cell. 2016 Sep 22;167(1):260-274.e22. doi: 10.1016/j.cell.2016.08.041. Epub 2016 Sep 15.

27.

Left Ventricular Rotational Mechanics in Children After Heart Transplantation.

Nawaytou HM, Yubbu P, Montero AE, Nandi D, O'Connor MJ, Shaddy RE, Banerjee A.

Circ Cardiovasc Imaging. 2016 Sep;9(9). pii: e004848. doi: 10.1161/CIRCIMAGING.116.004848.

28.

Mapping the complete glycoproteome of virion-derived HIV-1 gp120 provides insights into broadly neutralizing antibody binding.

Panico M, Bouché L, Binet D, O'Connor MJ, Rahman D, Pang PC, Canis K, North SJ, Desrosiers RC, Chertova E, Keele BF, Bess JW Jr, Lifson JD, Haslam SM, Dell A, Morris HR.

Sci Rep. 2016 Sep 8;6:32956. doi: 10.1038/srep32956.

29.

The PARP Inhibitor AZD2461 Provides Insights into the Role of PARP3 Inhibition for Both Synthetic Lethality and Tolerability with Chemotherapy in Preclinical Models.

Oplustil O'Connor L, Rulten SL, Cranston AN, Odedra R, Brown H, Jaspers JE, Jones L, Knights C, Evers B, Ting A, Bradbury RH, Pajic M, Rottenberg S, Jonkers J, Rudge D, Martin NM, Caldecott KW, Lau A, O'Connor MJ.

Cancer Res. 2016 Oct 15;76(20):6084-6094. Epub 2016 Aug 22.

30.

Gain-of-function mutations in SMAD4 cause a distinctive repertoire of cardiovascular phenotypes in patients with Myhre syndrome.

Lin AE, Michot C, Cormier-Daire V, L'Ecuyer TJ, Matherne GP, Barnes BH, Humberson JB, Edmondson AC, Zackai E, O'Connor MJ, Kaplan JD, Ebeid MR, Krier J, Krieg E, Ghoshhajra B, Lindsay ME.

Am J Med Genet A. 2016 Oct;170(10):2617-31. doi: 10.1002/ajmg.a.37739. Epub 2016 Jun 14. Review.

PMID:
27302097
31.

Clinical Characteristics of Children With Eosinophilic Cardiac Disease.

Butto A, Nandi D, O'Connor MJ.

Circ Heart Fail. 2016 Jun;9(6):e003172. doi: 10.1161/CIRCHEARTFAILURE.116.003172. Epub 2016 Jun 9. No abstract available.

32.

ATM protein is deficient in over 40% of lung adenocarcinomas.

Villaruz LC, Jones H, Dacic S, Abberbock S, Kurland BF, Stabile LP, Siegfried JM, Conrads TP, Smith NR, O'Connor MJ, Pierce AJ, Bakkenist CJ.

Oncotarget. 2016 Sep 6;7(36):57714-57725. doi: 10.18632/oncotarget.9757.

33.

Alcohol Intervention for Adolescents with Fetal Alcohol Spectrum Disorders: Project Step Up, a Treatment Development Study.

O'Connor MJ, Quattlebaum J, Castañeda M, Dipple KM.

Alcohol Clin Exp Res. 2016 Aug;40(8):1744-51. doi: 10.1111/acer.13111. Epub 2016 May 24.

PMID:
27219498
34.

Sequential 1,4-/1,2-Addition of Lithium(trimethylsilyl)diazomethane onto Cyclic Enones to Induce C-C Fragmentation and N-Li Insertion.

O'Connor MJ, Sun C, Guan X, Sabbasani VR, Lee D.

Angew Chem Int Ed Engl. 2016 Feb 5;55(6):2222-5. doi: 10.1002/anie.201510152. Epub 2015 Dec 22.

PMID:
26694997
35.

Familial long QT syndrome and late development of dilated cardiomyopathy in a child with a KCNQ1 mutation: A case report.

Allen KY, Vetter VL, Shah MJ, O'Connor MJ.

HeartRhythm Case Rep. 2015 Dec 18;2(2):128-131. doi: 10.1016/j.hrcr.2015.10.011. eCollection 2016 Mar. No abstract available.

36.

Hospital Charges for Pediatric Heart Failure-Related Hospitalizations from 2000 to 2009.

Nandi D, Lin KY, O'Connor MJ, Elci OU, Kim JJ, Decker JA, Price JF, Zafar F, Morales DL, Denfield SW, Dreyer WJ, Jefferies JL, Rossano JW.

Pediatr Cardiol. 2016 Mar;37(3):512-8. doi: 10.1007/s00246-015-1308-0. Epub 2015 Dec 8.

37.

DFT Studies on the Stereoselectivity of α-Silyloxy Diazoalkane Cycloadditions.

O'Connor MJ, Liu H, Lee D, Zhou T, Xia Y.

Molecules. 2015 Dec 2;20(12):21433-41. doi: 10.3390/molecules201219783.

38.

Targeting the DNA Damage Response in Cancer.

O'Connor MJ.

Mol Cell. 2015 Nov 19;60(4):547-60. doi: 10.1016/j.molcel.2015.10.040. Review.

39.

The orally active and bioavailable ATR kinase inhibitor AZD6738 potentiates the anti-tumor effects of cisplatin to resolve ATM-deficient non-small cell lung cancer in vivo.

Vendetti FP, Lau A, Schamus S, Conrads TP, O'Connor MJ, Bakkenist CJ.

Oncotarget. 2015 Dec 29;6(42):44289-305. doi: 10.18632/oncotarget.6247.

40.

An integrative Raman microscopy-based workflow for rapid in situ analysis of microalgal lipid bodies.

Sharma SK, Nelson DR, Abdrabu R, Khraiwesh B, Jijakli K, Arnoux M, O'Connor MJ, Bahmani T, Cai H, Khapli S, Jagannathan R, Salehi-Ashtiani K.

Biotechnol Biofuels. 2015 Oct 6;8:164. doi: 10.1186/s13068-015-0349-1. eCollection 2015.

41.

Randomized, Double-Blind Phase II Trial With Prospective Classification by ATM Protein Level to Evaluate the Efficacy and Tolerability of Olaparib Plus Paclitaxel in Patients With Recurrent or Metastatic Gastric Cancer.

Bang YJ, Im SA, Lee KW, Cho JY, Song EK, Lee KH, Kim YH, Park JO, Chun HG, Zang DY, Fielding A, Rowbottom J, Hodgson D, O'Connor MJ, Yin X, Kim WH.

J Clin Oncol. 2015 Nov 20;33(33):3858-65. doi: 10.1200/JCO.2014.60.0320. Epub 2015 Aug 17.

PMID:
26282658
42.

Neurobehavioral Disorder Associated with Prenatal Alcohol Exposure (ND-PAE): Proposed DSM-5 Diagnosis.

Kable JA, O'Connor MJ, Olson HC, Paley B, Mattson SN, Anderson SM, Riley EP.

Child Psychiatry Hum Dev. 2016 Apr;47(2):335-46. doi: 10.1007/s10578-015-0566-7. Review.

PMID:
26202432
43.

Changes in the methodology of pre-heart transplant human leukocyte antibody assessment: an analysis of the United Network for Organ Sharing database.

O'Connor MJ, Keeshan BC, Lin KY, Monos D, Lind C, Paridon SM, Mascio CE, Shaddy RE, Rossano JW.

Clin Transplant. 2015 Sep;29(9):842-50. doi: 10.1111/ctr.12590. Epub 2015 Aug 6.

PMID:
26172275
44.

The center for expanded data annotation and retrieval.

Musen MA, Bean CA, Cheung KH, Dumontier M, Durante KA, Gevaert O, Gonzalez-Beltran A, Khatri P, Kleinstein SH, O'Connor MJ, Pouliot Y, Rocca-Serra P, Sansone SA, Wiser JA; CEDAR team.

J Am Med Inform Assoc. 2015 Nov;22(6):1148-52. doi: 10.1093/jamia/ocv048. Epub 2015 Jun 25.

45.

Does the Presence of Scrapie Affect the Ability of Current Statutory Discriminatory Tests To Detect the Presence of Bovine Spongiform Encephalopathy?

Simmons MM, Chaplin MJ, Vickery CM, Simon S, Davis L, Denyer M, Lockey R, Stack MJ, O'Connor MJ, Bishop K, Gough KC, Maddison BC, Thorne L, Spiropoulos J.

J Clin Microbiol. 2015 Aug;53(8):2593-604. doi: 10.1128/JCM.00508-15. Epub 2015 Jun 3.

46.

Sudden cardiac death in pediatric cardiomyopathy: the importance of well-designed population-based studies.

Rossano JW, O'Connor MJ.

J Am Coll Cardiol. 2015 Jun 2;65(21):2311-3. doi: 10.1016/j.jacc.2015.04.004. No abstract available.

47.

Extent of radiosensitization by the PARP inhibitor olaparib depends on its dose, the radiation dose and the integrity of the homologous recombination pathway of tumor cells.

Verhagen CV, de Haan R, Hageman F, Oostendorp TP, Carli AL, O'Connor MJ, Jonkers J, Verheij M, van den Brekel MW, Vens C.

Radiother Oncol. 2015 Sep;116(3):358-65. doi: 10.1016/j.radonc.2015.03.028. Epub 2015 May 13.

PMID:
25981132
48.

Gp120 on HIV-1 Virions Lacks O-Linked Carbohydrate.

Stansell E, Panico M, Canis K, Pang PC, Bouché L, Binet D, O'Connor MJ, Chertova E, Bess J, Lifson JD, Haslam SM, Morris HR, Desrosiers RC, Dell A.

PLoS One. 2015 Apr 27;10(4):e0124784. doi: 10.1371/journal.pone.0124784. eCollection 2015.

49.

Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), enhances anti-tumor effects of the poly (ADP-ribose) polymerase (PARP) inhibitor olaparib in triple-negative breast cancer cells.

Min A, Im SA, Kim DK, Song SH, Kim HJ, Lee KH, Kim TY, Han SW, Oh DY, Kim TY, O'Connor MJ, Bang YJ.

Breast Cancer Res. 2015 Mar 7;17:33. doi: 10.1186/s13058-015-0534-y.

50.

Screening for fetal alcohol spectrum disorders by nonmedical community workers.

O'Connor MJ, Rotheram-Borus MJ, Tomlinson M, Bill C, LeRoux IM, Stewart J.

J Popul Ther Clin Pharmacol. 2014;21(3):e442-52. Epub 2014 Nov 18.

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