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Items: 1 to 50 of 119

1.

Fractionation enhances acute oligodendrocyte progenitor cell radiation sensitivity and leads to long term depletion.

Begolly S, Olschowka JA, Love T, Williams JP, O'Banion MK.

Glia. 2018 Apr;66(4):846-861. doi: 10.1002/glia.23288. Epub 2017 Dec 30.

PMID:
29288597
2.

Mitigating coastal landslide damage.

Leshchinsky B, Olsen MJ, Mohney C, Glover-Cutter K, Crook G, Allan J, Bunn M, O'Banion M, Mathews N.

Science. 2017 Sep 8;357(6355):981-982. doi: 10.1126/science.aao1722. No abstract available.

PMID:
28883065
3.

Reduced activation and proliferation of human lymphocytes exposed to respiratory syncytial virus compared to cells exposed to influenza virus.

Fleming EH, Ochoa EE, Nichols JE, O'Banion MK, Salkind AR, Roberts NJ Jr.

J Med Virol. 2018 Jan;90(1):26-33. doi: 10.1002/jmv.24917. Epub 2017 Sep 26.

PMID:
28856681
4.

Neurogenic Effects of Low-Dose Whole-Body HZE (Fe) Ion and Gamma Irradiation.

Sweet TB, Hurley SD, Wu MD, Olschowka JA, Williams JP, O'Banion MK.

Radiat Res. 2016 Dec;186(6):614-623. doi: 10.1667/RR14530.1. Epub 2016 Dec 1.

5.

Fractionation Spares Mice From Radiation-Induced Reductions in Weight Gain But Does Not Prevent Late Oligodendrocyte Lineage Side Effects.

Begolly S, Shrager PG, Olschowka JA, Williams JP, O'Banion MK.

Int J Radiat Oncol Biol Phys. 2016 Oct 1;96(2):449-457. doi: 10.1016/j.ijrobp.2016.05.005. Epub 2016 May 12.

6.

Editorial: mixed soluble fibre in chronic constipation - something new? Authors' reply.

Erdogan A, Rao SS, Thiruvaiyaru D, Lee YY, Coss Adame E, Valestin J, O'Banion M.

Aliment Pharmacol Ther. 2016 Aug;44(3):303. doi: 10.1111/apt.13688. No abstract available.

7.

Addressing the Symptoms or Fixing the Problem? Developing Countermeasures against Normal Tissue Radiation Injury.

Williams JP, Calvi L, Chakkalakal JV, Finkelstein JN, O'Banion MK, Puzas E.

Radiat Res. 2016 Jul;186(1):1-16. doi: 10.1667/RR14473.1. Epub 2016 Jun 22. Review. No abstract available.

8.

Targeting innate immunity for neurodegenerative disorders of the central nervous system.

Andreasson KI, Bachstetter AD, Colonna M, Ginhoux F, Holmes C, Lamb B, Landreth G, Lee DC, Low D, Lynch MA, Monsonego A, O'Banion MK, Pekny M, Puschmann T, Russek-Blum N, Sandusky LA, Selenica ML, Takata K, Teeling J, Town T, Van Eldik LJ.

J Neurochem. 2016 Sep;138(5):653-93. doi: 10.1111/jnc.13667. Review. Erratum in: J Neurochem. 2017 Apr;141(1):151.

9.

Randomised clinical trial: mixed soluble/insoluble fibre vs. psyllium for chronic constipation.

Erdogan A, Rao SS, Thiruvaiyaru D, Lee YY, Coss Adame E, Valestin J, O'Banion M.

Aliment Pharmacol Ther. 2016 Jul;44(1):35-44. doi: 10.1111/apt.13647. Epub 2016 Apr 29.

10.

Brain radiation injury leads to a dose- and time-dependent recruitment of peripheral myeloid cells that depends on CCR2 signaling.

Moravan MJ, Olschowka JA, Williams JP, O'Banion MK.

J Neuroinflammation. 2016 Feb 3;13:30. doi: 10.1186/s12974-016-0496-8.

11.

Arginase 1+ microglia reduce Aβ plaque deposition during IL-1β-dependent neuroinflammation.

Cherry JD, Olschowka JA, O'Banion MK.

J Neuroinflammation. 2015 Nov 4;12:203. doi: 10.1186/s12974-015-0411-8.

12.

Characterization of binge-dosed methamphetamine-induced neurotoxicity and neuroinflammation.

McConnell SE, O'Banion MK, Cory-Slechta DA, Olschowka JA, Opanashuk LA.

Neurotoxicology. 2015 Sep;50:131-41. doi: 10.1016/j.neuro.2015.08.006. Epub 2015 Aug 15.

13.

Are "resting" microglia more "m2"?

Cherry JD, Olschowka JA, O'Banion MK.

Front Immunol. 2014 Nov 18;5:594. doi: 10.3389/fimmu.2014.00594. eCollection 2014. Review. No abstract available.

14.

Does peripheral inflammation contribute to Alzheimer disease? Evidence from animal models.

O'Banion MK.

Neurology. 2014 Aug 5;83(6):480-1. doi: 10.1212/WNL.0000000000000663. Epub 2014 Jul 2. No abstract available.

PMID:
24991028
15.

Central nervous system effects of whole-body proton irradiation.

Sweet TB, Panda N, Hein AM, Das SL, Hurley SD, Olschowka JA, Williams JP, O'Banion MK.

Radiat Res. 2014 Jul;182(1):18-34. doi: 10.1667/RR13699.1. Epub 2014 Jun 17.

PMID:
24937778
16.

Neuroinflammation and M2 microglia: the good, the bad, and the inflamed.

Cherry JD, Olschowka JA, O'Banion MK.

J Neuroinflammation. 2014 Jun 3;11:98. doi: 10.1186/1742-2094-11-98. Review.

17.

Interleukin-1β mediated amyloid plaque clearance is independent of CCR2 signaling in the APP/PS1 mouse model of Alzheimer's disease.

Rivera-Escalera F, Matousek SB, Ghosh S, Olschowka JA, O'Banion MK.

Neurobiol Dis. 2014 Sep;69:124-33. doi: 10.1016/j.nbd.2014.05.018. Epub 2014 May 27.

18.

Thermal injury lowers the threshold for radiation-induced neuroinflammation and cognitive dysfunction.

Cherry JD, Williams JP, O'Banion MK, Olschowka JA.

Radiat Res. 2013 Oct;180(4):398-406. doi: 10.1667/RR3363.1. Epub 2013 Sep 23.

19.

Synthesis of 15-methylene-eburnamonine from (+)-vincamine, evaluation of anticancer activity, and investigation of mechanism of action by quantitative NMR.

Woods JR, Riofski MV, Zheng MM, O'Banion MA, Mo H, Kirshner J, Colby DA.

Bioorg Med Chem Lett. 2013 Nov 1;23(21):5865-9. doi: 10.1016/j.bmcl.2013.08.095. Epub 2013 Sep 6.

20.

It may take more than a shot: alternatives to immunotherapy for Alzheimer's disease.

O'Banion MK.

Biol Psychiatry. 2013 Sep 1;74(5):316-7. doi: 10.1016/j.biopsych.2013.07.003. No abstract available.

PMID:
23932341
21.

Soluble-E-cadherin activates HER and IAP family members in HER2+ and TNBC human breast cancers.

Brouxhon SM, Kyrkanides S, Teng X, O'Banion MK, Clarke R, Byers S, Ma L.

Mol Carcinog. 2014 Nov;53(11):893-906. doi: 10.1002/mc.22048. Epub 2013 Jun 18.

22.

Monoclonal antibody against the ectodomain of E-cadherin (DECMA-1) suppresses breast carcinogenesis: involvement of the HER/PI3K/Akt/mTOR and IAP pathways.

Brouxhon SM, Kyrkanides S, Teng X, Raja V, O'Banion MK, Clarke R, Byers S, Silberfeld A, Tornos C, Ma L.

Clin Cancer Res. 2013 Jun 15;19(12):3234-46. doi: 10.1158/1078-0432.CCR-12-2747. Epub 2013 Apr 25.

23.

Chronic neuron- and age-selective down-regulation of TNF receptor expression in triple-transgenic Alzheimer disease mice leads to significant modulation of amyloid- and Tau-related pathologies.

Montgomery SL, Narrow WC, Mastrangelo MA, Olschowka JA, O'Banion MK, Bowers WJ.

Am J Pathol. 2013 Jun;182(6):2285-97. doi: 10.1016/j.ajpath.2013.02.030. Epub 2013 Apr 6.

24.

Sustained IL-1β expression impairs adult hippocampal neurogenesis independent of IL-1 signaling in nestin+ neural precursor cells.

Wu MD, Montgomery SL, Rivera-Escalera F, Olschowka JA, O'Banion MK.

Brain Behav Immun. 2013 Aug;32:9-18. doi: 10.1016/j.bbi.2013.03.003. Epub 2013 Mar 16.

25.

Sustained interleukin-1β overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model.

Ghosh S, Wu MD, Shaftel SS, Kyrkanides S, LaFerla FM, Olschowka JA, O'Banion MK.

J Neurosci. 2013 Mar 13;33(11):5053-64. doi: 10.1523/JNEUROSCI.4361-12.2013.

26.

Soluble E-cadherin: a critical oncogene modulating receptor tyrosine kinases, MAPK and PI3K/Akt/mTOR signaling.

Brouxhon SM, Kyrkanides S, Teng X, Athar M, Ghazizadeh S, Simon M, O'Banion MK, Ma L.

Oncogene. 2014 Jan 9;33(2):225-35. doi: 10.1038/onc.2012.563. Epub 2013 Jan 14.

27.

Galactic cosmic radiation leads to cognitive impairment and increased aβ plaque accumulation in a mouse model of Alzheimer's disease.

Cherry JD, Liu B, Frost JL, Lemere CA, Williams JP, Olschowka JA, O'Banion MK.

PLoS One. 2012;7(12):e53275. doi: 10.1371/journal.pone.0053275. Epub 2012 Dec 31.

28.

Deletion or activation of the aryl hydrocarbon receptor alters adult hippocampal neurogenesis and contextual fear memory.

Latchney SE, Hein AM, O'Banion MK, DiCicco-Bloom E, Opanashuk LA.

J Neurochem. 2013 May;125(3):430-45. doi: 10.1111/jnc.12130. Epub 2013 Jan 7.

29.

X-ray microbeam irradiation of the contusion-injured rat spinal cord temporarily improves hind-limb function.

Dilmanian FA, Jenkins AL 3rd, Olschowka JA, Zhong Z, Park JY, Desnoyers NR, Sobotka S, Fois GR, Messina CR, Morales M, Hurley SD, Trojanczyk L, Ahmad S, Shahrabi N, Coyle PK, Meek AG, O'Banion MK.

Radiat Res. 2013 Jan;179(1):76-88. doi: 10.1667/RR2921.1. Epub 2012 Dec 5.

PMID:
23216524
30.

Conditional expression of human β-hexosaminidase in the neurons of Sandhoff disease rescues mice from neurodegeneration but not neuroinflammation.

Kyrkanides S, Brouxhon SM, Tallents RH, Miller JN, Olschowka JA, O'Banion MK.

J Neuroinflammation. 2012 Aug 4;9:186.

31.

Interleaved carbon minibeams: an experimental radiosurgery method with clinical potential.

Dilmanian FA, Rusek A, Fois GR, Olschowka J, Desnoyers NR, Park JY, Dioszegi I, Dane B, Wang R, Tomasi D, Lee H, Hurley SD, Coyle PK, Meek AG, O'Banion MK.

Int J Radiat Oncol Biol Phys. 2012 Oct 1;84(2):514-9. doi: 10.1016/j.ijrobp.2011.12.025. Epub 2012 Feb 17.

PMID:
22342299
32.

Neuroinflammation and cognitive dysfunction in chronic disease and aging.

Hein AM, O'Banion MK.

J Neuroimmune Pharmacol. 2012 Mar;7(1):3-6. doi: 10.1007/s11481-011-9340-1. Epub 2012 Jan 18. No abstract available.

PMID:
22252623
33.

Chronic IL-1β-mediated neuroinflammation mitigates amyloid pathology in a mouse model of Alzheimer's disease without inducing overt neurodegeneration.

Matousek SB, Ghosh S, Shaftel SS, Kyrkanides S, Olschowka JA, O'Banion MK.

J Neuroimmune Pharmacol. 2012 Mar;7(1):156-64. doi: 10.1007/s11481-011-9331-2. Epub 2011 Dec 16.

34.

Acute neuroinflammation and neurogenesis: a role for microglial COX-1.

O'Banion MK.

Cell Cycle. 2011 Nov 15;10(22):3819-20. doi: 10.4161/cc.10.22.18193. Epub 2011 Nov 15. No abstract available.

PMID:
22142863
35.

Adult murine hippocampal neurogenesis is inhibited by sustained IL-1β and not rescued by voluntary running.

Wu MD, Hein AM, Moravan MJ, Shaftel SS, Olschowka JA, O'Banion MK.

Brain Behav Immun. 2012 Feb;26(2):292-300. doi: 10.1016/j.bbi.2011.09.012. Epub 2011 Sep 29.

36.

Osteoarthritis accelerates and exacerbates Alzheimer's disease pathology in mice.

Kyrkanides S, Tallents RH, Miller JN, Olschowka ME, Johnson R, Yang M, Olschowka JA, Brouxhon SM, O'Banion MK.

J Neuroinflammation. 2011 Sep 7;8:112. doi: 10.1186/1742-2094-8-112.

37.
38.

Behavioral, structural and molecular changes following long-term hippocampal IL-1β overexpression in transgenic mice.

Hein AM, Zarcone TJ, Parfitt DB, Matousek SB, Carbonari DM, Olschowka JA, O'Banion MK.

J Neuroimmune Pharmacol. 2012 Mar;7(1):145-55. doi: 10.1007/s11481-011-9294-3. Epub 2011 Jul 12.

39.

Medical Scientist Training Programs: federal funding offers support and drives innovation.

Andersen OS, O'Banion MK.

Acad Med. 2010 Oct;85(10):1559. doi: 10.1097/ACM.0b013e3181f1195d. No abstract available.

PMID:
20881674
40.

Neuroinflammatory processes in Alzheimer's disease.

Heneka MT, O'Banion MK, Terwel D, Kummer MP.

J Neural Transm (Vienna). 2010 Aug;117(8):919-47. doi: 10.1007/s00702-010-0438-z. Epub 2010 Jul 15. Review.

PMID:
20632195
41.

Cyclooxygenase-1 mediates prostaglandin E(2) elevation and contextual memory impairment in a model of sustained hippocampal interleukin-1beta expression.

Matousek SB, Hein AM, Shaftel SS, Olschowka JA, Kyrkanides S, O'Banion MK.

J Neurochem. 2010 Jul;114(1):247-58. doi: 10.1111/j.1471-4159.2010.06759.x. Epub 2010 Apr 19.

42.

Sustained hippocampal IL-1beta overexpression impairs contextual and spatial memory in transgenic mice.

Hein AM, Stasko MR, Matousek SB, Scott-McKean JJ, Maier SF, Olschowka JA, Costa AC, O'Banion MK.

Brain Behav Immun. 2010 Feb;24(2):243-53. doi: 10.1016/j.bbi.2009.10.002. Epub 2009 Oct 13.

43.

Sustained expression of interleukin-1beta in mouse hippocampus impairs spatial memory.

Moore AH, Wu M, Shaftel SS, Graham KA, O'Banion MK.

Neuroscience. 2009 Dec 29;164(4):1484-95. doi: 10.1016/j.neuroscience.2009.08.073. Epub 2009 Sep 8.

44.

Prostaglandin E2 synthases in neurologic homeostasis and disease.

O'Banion MK.

Prostaglandins Other Lipid Mediat. 2010 Apr;91(3-4):113-7. doi: 10.1016/j.prostaglandins.2009.04.008. Epub 2009 Apr 22. Review.

45.

Neuroinflammation and memory: the role of prostaglandins.

Hein AM, O'Banion MK.

Mol Neurobiol. 2009 Aug;40(1):15-32. doi: 10.1007/s12035-009-8066-z. Epub 2009 Apr 14. Review.

46.

Restructuring MD-PhD programs: career training or broad education?

Ahn J, Nguyen FT, Mann JR, O'Banion MK.

Acad Med. 2009 Apr;84(4):407; author reply 407-8. doi: 10.1097/ACM.0b013e31819a82d2. No abstract available.

PMID:
19318763
47.

Spinal interleukin-1beta in a mouse model of arthritis and joint pain.

Fiorentino PM, Tallents RH, Miller JN, Brouxhon SM, O'Banion MK, Puzas JE, Kyrkanides S.

Arthritis Rheum. 2008 Oct;58(10):3100-9. doi: 10.1002/art.23866.

48.

Peripheral blood mononuclear cell infiltration and neuroinflammation in the HexB-/- mouse model of neurodegeneration.

Kyrkanides S, Miller AW, Miller JN, Tallents RH, Brouxhon SM, Olschowka ME, O'Banion MK, Olschowka JA.

J Neuroimmunol. 2008 Oct 15;203(1):50-7. doi: 10.1016/j.jneuroim.2008.06.024.

49.

ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration.

Zhong Z, Deane R, Ali Z, Parisi M, Shapovalov Y, O'Banion MK, Stojanovic K, Sagare A, Boillee S, Cleveland DW, Zlokovic BV.

Nat Neurosci. 2008 Apr;11(4):420-2. doi: 10.1038/nn2073. Epub 2008 Mar 16.

50.

The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective.

Shaftel SS, Griffin WS, O'Banion MK.

J Neuroinflammation. 2008 Feb 26;5:7. doi: 10.1186/1742-2094-5-7. Review.

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