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Items: 1 to 50 of 182

1.

Association of Regulatory T-Cell Expansion With Progression of Amyotrophic Lateral Sclerosis: A Study of Humans and a Transgenic Mouse Model.

Sheean RK, McKay FC, Cretney E, Bye CR, Perera ND, Tomas D, Weston RA, Scheller KJ, Djouma E, Menon P, Schibeci SD, Marmash N, Yerbury JJ, Nutt SL, Booth DR, Stewart GJ, Kiernan MC, Vucic S, Turner BJ.

JAMA Neurol. 2018 Mar 5. doi: 10.1001/jamaneurol.2018.0035. [Epub ahead of print]

PMID:
29507931
2.

Environmental sensing by mature B cells is controlled by the transcription factors PU.1 and SpiB.

Willis SN, Tellier J, Liao Y, Trezise S, Light A, O'Donnell K, Garrett-Sinha LA, Shi W, Tarlinton DM, Nutt SL.

Nat Commun. 2017 Nov 10;8(1):1426. doi: 10.1038/s41467-017-01605-1.

3.

Interleukin-12 from CD103+ Batf3-Dependent Dendritic Cells Required for NK-Cell Suppression of Metastasis.

Mittal D, Vijayan D, Putz EM, Aguilera AR, Markey KA, Straube J, Kazakoff S, Nutt SL, Takeda K, Hill GR, Waddell N, Smyth MJ.

Cancer Immunol Res. 2017 Dec;5(12):1098-1108. doi: 10.1158/2326-6066.CIR-17-0341. Epub 2017 Oct 25.

PMID:
29070650
4.

Natural-Killer-like B Cells Display the Phenotypic and Functional Characteristics of Conventional B Cells.

Kerdiles YM, Almeida FF, Thompson T, Chopin M, Vienne M, Bruhns P, Huntington ND, Raulet DH, Nutt SL, Belz GT, Vivier E.

Immunity. 2017 Aug 15;47(2):199-200. doi: 10.1016/j.immuni.2017.07.026. No abstract available.

5.

Standing out from the crowd: How to identify plasma cells.

Tellier J, Nutt SL.

Eur J Immunol. 2017 Aug;47(8):1276-1279. doi: 10.1002/eji.201747168.

PMID:
28787106
6.

Correction: TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1.

Etemadi N, Chopin M, Anderton H, Tanzer MC, Rickard JA, Abeysekera W, Hall C, Spall SK, Wang B, Xiong Y, Hla T, Pitson SM, Bonder CS, Wong WW, Ernst M, Smyth GK, Vaux DL, Nutt SL, Nachbur U, Silke J.

Elife. 2017 Jun 27;6. pii: e29849. doi: 10.7554/eLife.29849. No abstract available.

7.

IL-17-producing γδ T cells switch migratory patterns between resting and activated states.

McKenzie DR, Kara EE, Bastow CR, Tyllis TS, Fenix KA, Gregor CE, Wilson JJ, Babb R, Paton JC, Kallies A, Nutt SL, Brüstle A, Mack M, Comerford I, McColl SR.

Nat Commun. 2017 Jun 5;8:15632. doi: 10.1038/ncomms15632.

8.

Genome-Wide Identification of Target Genes for the Key B Cell Transcription Factor Ets1.

Saelee P, Kearly A, Nutt SL, Garrett-Sinha LA.

Front Immunol. 2017 Apr 7;8:383. doi: 10.3389/fimmu.2017.00383. eCollection 2017.

9.

The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger.

Keightley MC, Carradice DP, Layton JE, Pase L, Bertrand JY, Wittig JG, Dakic A, Badrock AP, Cole NJ, Traver D, Nutt SL, McCoey J, Buckle AM, Heath JK, Lieschke GJ.

Nat Commun. 2017 Apr 6;8:14911. doi: 10.1038/ncomms14911.

10.

A non-canonical function of Ezh2 preserves immune homeostasis.

Vasanthakumar A, Xu D, Lun AT, Kueh AJ, van Gisbergen KP, Iannarella N, Li X, Yu L, Wang D, Williams BR, Lee SC, Majewski IJ, Godfrey DI, Smyth GK, Alexander WS, Herold MJ, Kallies A, Nutt SL, Allan RS.

EMBO Rep. 2017 Apr;18(4):619-631. doi: 10.15252/embr.201643237. Epub 2017 Feb 21.

11.

Effector Regulatory T Cell Differentiation and Immune Homeostasis Depend on the Transcription Factor Myb.

Dias S, D'Amico A, Cretney E, Liao Y, Tellier J, Bruggeman C, Almeida FF, Leahy J, Belz GT, Smyth GK, Shi W, Nutt SL.

Immunity. 2017 Jan 17;46(1):78-91. doi: 10.1016/j.immuni.2016.12.017.

12.

NKG2C/E Marks the Unique Cytotoxic CD4 T Cell Subset, ThCTL, Generated by Influenza Infection.

Marshall NB, Vong AM, Devarajan P, Brauner MD, Kuang Y, Nayar R, Schutten EA, Castonguay CH, Berg LJ, Nutt SL, Swain SL.

J Immunol. 2017 Feb 1;198(3):1142-1155. doi: 10.4049/jimmunol.1601297. Epub 2016 Dec 28.

13.

Mature IgM-expressing plasma cells sense antigen and develop competence for cytokine production upon antigenic challenge.

Blanc P, Moro-Sibilot L, Barthly L, Jagot F, This S, de Bernard S, Buffat L, Dussurgey S, Colisson R, Hobeika E, Fest T, Taillardet M, Thaunat O, Sicard A, Mondière P, Genestier L, Nutt SL, Defrance T.

Nat Commun. 2016 Dec 7;7:13600. doi: 10.1038/ncomms13600.

14.

Opposing Development of Cytotoxic and Follicular Helper CD4 T Cells Controlled by the TCF-1-Bcl6 Nexus.

Donnarumma T, Young GR, Merkenschlager J, Eksmond U, Bongard N, Nutt SL, Boyer C, Dittmer U, Le-Trilling VT, Trilling M, Bayer W, Kassiotis G.

Cell Rep. 2016 Nov 1;17(6):1571-1583. doi: 10.1016/j.celrep.2016.10.013.

15.

Acetylation of the Cd8 Locus by KAT6A Determines Memory T Cell Diversity.

Newman DM, Sakaguchi S, Lun A, Preston S, Pellegrini M, Khamina K, Bergthaler A, Nutt SL, Smyth GK, Voss AK, Thomas T, Ellmeier W, Belz GT, Allan RS.

Cell Rep. 2016 Sep 20;16(12):3311-3321. doi: 10.1016/j.celrep.2016.08.056.

16.

Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation.

Achuthan A, Cook AD, Lee MC, Saleh R, Khiew HW, Chang MW, Louis C, Fleetwood AJ, Lacey DC, Christensen AD, Frye AT, Lam PY, Kusano H, Nomura K, Steiner N, Förster I, Nutt SL, Olshansky M, Turner SJ, Hamilton JA.

J Clin Invest. 2016 Sep 1;126(9):3453-66. doi: 10.1172/JCI87828. Epub 2016 Aug 15.

17.

Long-Lived Plasma Cells Have a Sweet Tooth.

Corcoran LM, Nutt SL.

Immunity. 2016 Jul 19;45(1):3-5. doi: 10.1016/j.immuni.2016.07.003.

18.

Dynamic changes in Id3 and E-protein activity orchestrate germinal center and plasma cell development.

Gloury R, Zotos D, Zuidscherwoude M, Masson F, Liao Y, Hasbold J, Corcoran LM, Hodgkin PD, Belz GT, Shi W, Nutt SL, Tarlinton DM, Kallies A.

J Exp Med. 2016 May 30;213(6):1095-111. doi: 10.1084/jem.20152003. Epub 2016 May 23.

19.

RUNX2 Mediates Plasmacytoid Dendritic Cell Egress from the Bone Marrow and Controls Viral Immunity.

Chopin M, Preston SP, Lun ATL, Tellier J, Smyth GK, Pellegrini M, Belz GT, Corcoran LM, Visvader JE, Wu L, Nutt SL.

Cell Rep. 2016 Apr 26;15(4):866-878. doi: 10.1016/j.celrep.2016.03.066. Epub 2016 Apr 14.

20.

Th17 cell differentiation proceeds independently of IRF8.

Newman DM, Leung PS, Putoczki TL, Nutt SL, Cretney E.

Immunol Cell Biol. 2016 Sep;94(8):796-801. doi: 10.1038/icb.2016.33. Epub 2016 May 3.

PMID:
27140932
21.

A molecular threshold for effector CD8(+) T cell differentiation controlled by transcription factors Blimp-1 and T-bet.

Xin A, Masson F, Liao Y, Preston S, Guan T, Gloury R, Olshansky M, Lin JX, Li P, Speed TP, Smyth GK, Ernst M, Leonard WJ, Pellegrini M, Kaech SM, Nutt SL, Shi W, Belz GT, Kallies A.

Nat Immunol. 2016 Apr;17(4):422-32. doi: 10.1038/ni.3410. Epub 2016 Mar 7.

22.

PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia.

Pang SH, Minnich M, Gangatirkar P, Zheng Z, Ebert A, Song G, Dickins RA, Corcoran LM, Mullighan CG, Busslinger M, Huntington ND, Nutt SL, Carotta S.

Leukemia. 2016 Jun;30(6):1375-87. doi: 10.1038/leu.2016.27. Epub 2016 Mar 2.

23.

Correction: Blimp-1-Dependent IL-10 Production by Tr1 Cells Regulates TNF-Mediated Tissue Pathology.

Montes de Oca M, Kumar R, de Labastida Rivera F, Amante FH, Sheel M, Faleiro RJ, Bunn PT, Best SE, Beattie L, Ng SS, Edwards CL, Muller W, Cretney E, Nutt SL, Smyth MJ, Haque A, Hill GR, Sundar S, Kallies A, Engwerda CR.

PLoS Pathog. 2016 Feb 12;12(2):e1005460. doi: 10.1371/journal.ppat.1005460. eCollection 2016 Feb. No abstract available.

24.

The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15.

Delconte RB, Shi W, Sathe P, Ushiki T, Seillet C, Minnich M, Kolesnik TB, Rankin LC, Mielke LA, Zhang JG, Busslinger M, Smyth MJ, Hutchinson DS, Nutt SL, Nicholson SE, Alexander WS, Corcoran LM, Vivier E, Belz GT, Carotta S, Huntington ND.

Immunity. 2016 Jan 19;44(1):103-115. doi: 10.1016/j.immuni.2015.12.007. Epub 2016 Jan 12.

25.

Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation.

Minnich M, Tagoh H, Bönelt P, Axelsson E, Fischer M, Cebolla B, Tarakhovsky A, Nutt SL, Jaritz M, Busslinger M.

Nat Immunol. 2016 Mar;17(3):331-43. doi: 10.1038/ni.3349. Epub 2016 Jan 18.

26.

Blimp-1 controls plasma cell function through the regulation of immunoglobulin secretion and the unfolded protein response.

Tellier J, Shi W, Minnich M, Liao Y, Crawford S, Smyth GK, Kallies A, Busslinger M, Nutt SL.

Nat Immunol. 2016 Mar;17(3):323-30. doi: 10.1038/ni.3348. Epub 2016 Jan 18.

27.

Blimp-1-Dependent IL-10 Production by Tr1 Cells Regulates TNF-Mediated Tissue Pathology.

Montes de Oca M, Kumar R, de Labastida Rivera F, Amante FH, Sheel M, Faleiro RJ, Bunn PT, Best SE, Beattie L, Ng SS, Edwards CL, Muller W, Cretney E, Nutt SL, Smyth MJ, Haque A, Hill GR, Sundar S, Kallies A, Engwerda CR.

PLoS Pathog. 2016 Jan 14;12(1):e1005398. doi: 10.1371/journal.ppat.1005398. eCollection 2016 Jan. Erratum in: PLoS Pathog. 2016 Feb;12(2):e1005460.

28.

Severe Malaria Infections Impair Germinal Center Responses by Inhibiting T Follicular Helper Cell Differentiation.

Ryg-Cornejo V, Ioannidis LJ, Ly A, Chiu CY, Tellier J, Hill DL, Preston SP, Pellegrini M, Yu D, Nutt SL, Kallies A, Hansen DS.

Cell Rep. 2016 Jan 5;14(1):68-81. doi: 10.1016/j.celrep.2015.12.006. Epub 2015 Dec 24.

29.

TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1.

Etemadi N, Chopin M, Anderton H, Tanzer MC, Rickard JA, Abeysekera W, Hall C, Spall SK, Wang B, Xiong Y, Hla T, Pitson SM, Bonder CS, Wong WW, Ernst M, Smyth GK, Vaux DL, Nutt SL, Nachbur U, Silke J.

Elife. 2015 Dec 23;4. pii: e10592. doi: 10.7554/eLife.10592. Erratum in: Elife. 2017 Jun 27;6:.

30.

Whole transcriptome analysis for T cell receptor-affinity and IRF4-regulated clonal expansion of T cells.

Shi W, Man K, Smyth GK, Nutt SL, Kallies A.

Genom Data. 2014 Nov 1;2:396-8. doi: 10.1016/j.gdata.2014.10.019. eCollection 2014 Dec.

31.

The flavors of plasma cells.

Corcoran LM, Nutt SL.

Oncotarget. 2015 Oct 20;6(32):32305-6. doi: 10.18632/oncotarget.4631. No abstract available.

32.

Interleukin-21-Producing CD4(+) T Cells Promote Type 2 Immunity to House Dust Mites.

Coquet JM, Schuijs MJ, Smyth MJ, Deswarte K, Beyaert R, Braun H, Boon L, Karlsson Hedestam GB, Nutt SL, Hammad H, Lambrecht BN.

Immunity. 2015 Aug 18;43(2):318-30. doi: 10.1016/j.immuni.2015.07.015.

33.

Pillars Article: Commitment to the B-lymphoid lineage depends on the transcription factor Pax5. Nature. 1999. 401: 556-562.

Nutt SL, Heavey B, Rolink AG, Busslinger M.

J Immunol. 2015 Aug 1;195(3):766-72. No abstract available.

34.

Targeting Antigen to Clec9A Primes Follicular Th Cell Memory Responses Capable of Robust Recall.

Kato Y, Zaid A, Davey GM, Mueller SN, Nutt SL, Zotos D, Tarlinton DM, Shortman K, Lahoud MH, Heath WR, Caminschi I.

J Immunol. 2015 Aug 1;195(3):1006-14. doi: 10.4049/jimmunol.1500767. Epub 2015 Jun 22.

35.

c-Myb is required for plasma cell migration to bone marrow after immunization or infection.

Good-Jacobson KL, O'Donnell K, Belz GT, Nutt SL, Tarlinton DM.

J Exp Med. 2015 Jun 29;212(7):1001-9. doi: 10.1084/jem.20150191. Epub 2015 Jun 15.

36.

Erratum: The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells.

Vasanthakumar A, Moro K, Xin A, Liao Y, Gloury R, Kawamoto S, Fagarasan S, Mielke LA, Afshar-Sterle S, Masters SL, Nakae S, Saito H, Wentworth JM, Li P, Liao W, Leonard WJ, Smyth GK, Shi W, Nutt SL, Koyasu S, Kallies A.

Nat Immunol. 2015 May;16(5):544. doi: 10.1038/ni0515-544d. No abstract available.

PMID:
25898200
37.

Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells.

Shi W, Liao Y, Willis SN, Taubenheim N, Inouye M, Tarlinton DM, Smyth GK, Hodgkin PD, Nutt SL, Corcoran LM.

Nat Immunol. 2015 Jun;16(6):663-73. doi: 10.1038/ni.3154. Epub 2015 Apr 20.

PMID:
25894659
38.

Effect of thymic stimulation of CD4+ T cell expansion on disease onset and progression in mutant SOD1 mice.

Sheean RK, Weston RH, Perera ND, D'Amico A, Nutt SL, Turner BJ.

J Neuroinflammation. 2015 Feb 27;12:40. doi: 10.1186/s12974-015-0254-3.

39.

Mitochondrial function provides instructive signals for activation-induced B-cell fates.

Jang KJ, Mano H, Aoki K, Hayashi T, Muto A, Nambu Y, Takahashi K, Itoh K, Taketani S, Nutt SL, Igarashi K, Shimizu A, Sugai M.

Nat Commun. 2015 Apr 10;6:6750. doi: 10.1038/ncomms7750.

40.

Regulation of early T-lineage gene expression and developmental progression by the progenitor cell transcription factor PU.1.

Champhekar A, Damle SS, Freedman G, Carotta S, Nutt SL, Rothenberg EV.

Genes Dev. 2015 Apr 15;29(8):832-48. doi: 10.1101/gad.259879.115. Epub 2015 Apr 6.

41.

PU.1 downregulation in murine radiation-induced acute myeloid leukaemia (AML): from molecular mechanism to human AML.

Verbiest T, Bouffler S, Nutt SL, Badie C.

Carcinogenesis. 2015 Apr;36(4):413-9. doi: 10.1093/carcin/bgv016. Epub 2015 Mar 6. Review.

42.

The generation of antibody-secreting plasma cells.

Nutt SL, Hodgkin PD, Tarlinton DM, Corcoran LM.

Nat Rev Immunol. 2015 Mar;15(3):160-71. doi: 10.1038/nri3795. Epub 2015 Feb 20. Review.

PMID:
25698678
43.

Donald Metcalf (1929-2014).

Nutt SL.

Immunol Cell Biol. 2015 Mar;93(3):219-20. doi: 10.1038/icb.2015.11. Epub 2015 Feb 10. No abstract available.

PMID:
25666093
44.

Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia.

Witkowski MT, Cimmino L, Hu Y, Trimarchi T, Tagoh H, McKenzie MD, Best SA, Tuohey L, Willson TA, Nutt SL, Busslinger M, Aifantis I, Smyth GK, Dickins RA.

Leukemia. 2015 Jun;29(6):1301-11. doi: 10.1038/leu.2015.27. Epub 2015 Feb 6.

45.

MOZ regulates B-cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development.

Sheikh BN, Lee SC, El-Saafin F, Vanyai HK, Hu Y, Pang SH, Grabow S, Strasser A, Nutt SL, Alexander WS, Smyth GK, Voss AK, Thomas T.

Blood. 2015 Mar 19;125(12):1910-21. doi: 10.1182/blood-2014-08-594655. Epub 2015 Jan 20.

46.

The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells.

Vasanthakumar A, Moro K, Xin A, Liao Y, Gloury R, Kawamoto S, Fagarasan S, Mielke LA, Afshar-Sterle S, Masters SL, Nakae S, Saito H, Wentworth JM, Li P, Liao W, Leonard WJ, Smyth GK, Shi W, Nutt SL, Koyasu S, Kallies A.

Nat Immunol. 2015 Mar;16(3):276-85. doi: 10.1038/ni.3085. Epub 2015 Jan 19. Erratum in: Nat Immunol. 2015 May;16(5):544.

PMID:
25599561
47.

Interleukin-10-producing plasmablasts exert regulatory function in autoimmune inflammation.

Matsumoto M, Baba A, Yokota T, Nishikawa H, Ohkawa Y, Kayama H, Kallies A, Nutt SL, Sakaguchi S, Takeda K, Kurosaki T, Baba Y.

Immunity. 2014 Dec 18;41(6):1040-51. doi: 10.1016/j.immuni.2014.10.016. Epub 2014 Nov 4.

48.

Peripheral natural killer cell maturation depends on the transcription factor Aiolos.

Holmes ML, Huntington ND, Thong RP, Brady J, Hayakawa Y, Andoniou CE, Fleming P, Shi W, Smyth GK, Degli-Esposti MA, Belz GT, Kallies A, Carotta S, Smyth MJ, Nutt SL.

EMBO J. 2014 Nov 18;33(22):2721-34. doi: 10.15252/embj.201487900. Epub 2014 Oct 15.

49.

The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation.

Carotta S, Willis SN, Hasbold J, Inouye M, Pang SH, Emslie D, Light A, Chopin M, Shi W, Wang H, Morse HC 3rd, Tarlinton DM, Corcoran LM, Hodgkin PD, Nutt SL.

J Exp Med. 2014 Oct 20;211(11):2169-81. doi: 10.1084/jem.20140425. Epub 2014 Oct 6.

50.

The miR-155-PU.1 axis acts on Pax5 to enable efficient terminal B cell differentiation.

Lu D, Nakagawa R, Lazzaro S, Staudacher P, Abreu-Goodger C, Henley T, Boiani S, Leyland R, Galloway A, Andrews S, Butcher G, Nutt SL, Turner M, Vigorito E.

J Exp Med. 2014 Oct 20;211(11):2183-98. doi: 10.1084/jem.20140338. Epub 2014 Oct 6.

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